-
1
-
-
0020554896
-
Cell transformation by chemical agents - A review and analysis of the literature
-
Heidelberger, C., Freeman, A.E., Pienta, R.J., Sivak, A., Bertram, J.S., Casto, B.C., Dunkel, V.C., Francis, M.W., Kakunaga, T., Little, J.B. & Schechtman, L.M. (1983). Cell transformation by chemical agents - a review and analysis of the literature. Mutation Research 114, 283-385.
-
(1983)
Mutation Research
, vol.114
, pp. 283-385
-
-
Heidelberger, C.1
Freeman, A.E.2
Pienta, R.J.3
Sivak, A.4
Bertram, J.S.5
Casto, B.C.6
Dunkel, V.C.7
Francis, M.W.8
Kakunaga, T.9
Little, J.B.10
Schechtman, L.M.11
-
2
-
-
84969069250
-
Cellular and molecular mechanisms of cell transformation and standardization of transformation assays of established cell lines for the prediction of carcinogenic chemicals: Overview and recommended protocols
-
IARC/NCI/EPA
-
IARC/NCI/EPA (1985). Cellular and molecular mechanisms of cell transformation and standardization of transformation assays of established cell lines for the prediction of carcinogenic chemicals: Overview and recommended protocols. Cancer Research 45, 2395-2399.
-
(1985)
Cancer Research
, vol.45
, pp. 2395-2399
-
-
-
3
-
-
0027485609
-
Transformation of BALB/c 3T3 cells: V. Transformation responses of 168 chemicals compared with mutagenicity in Salmonella and carcinogenicity in rodent bioassays
-
Matthews, E.J., Spalding, J.W. & Tennant, R.W. (1993). Transformation of BALB/c 3T3 cells: V. Transformation responses of 168 chemicals compared with mutagenicity in Salmonella and carcinogenicity in rodent bioassays. Environmental Health Perspectives 101, Suppl. 2, 347-482.
-
(1993)
Environmental Health Perspectives
, vol.101
, Issue.SUPPL. 2
, pp. 347-482
-
-
Matthews, E.J.1
Spalding, J.W.2
Tennant, R.W.3
-
5
-
-
84965831796
-
Two-stage chemical carcinogenesis in cultures of C3H/10T1/2 cells
-
Mondal, S., Brankow, D.W. & Heidelberger, C. (1976). Two-stage chemical carcinogenesis in cultures of C3H/10T1/2 cells. Cancer Research 36, 2254-2260.
-
(1976)
Cancer Research
, vol.36
, pp. 2254-2260
-
-
Mondal, S.1
Brankow, D.W.2
Heidelberger, C.3
-
6
-
-
0024357790
-
Improvement of carcinogen identification in BALB/3T3 cell transformation by application of a 2-stage method
-
Sakai, A. & Sato, M. (1989). Improvement of carcinogen identification in BALB/3T3 cell transformation by application of a 2-stage method. Mutation Research 214, 285-296. (Pubitemid 19245419)
-
(1989)
Mutation Research
, vol.214
, Issue.2
, pp. 285-296
-
-
Sakai, A.1
Sato, M.2
-
7
-
-
0029085520
-
Improvement in the efficiency of the in vitro transformation assay method using BALB/3T3 A31-1-1 cells
-
Tsuchiya, T. & Umeda, M. (1995). Improvement in the efficiency of the in vitro transformation assay method using BALB/3T3 A31-1-1 cells. Carcinogenesis 16, 1887-1894.
-
(1995)
Carcinogenesis
, vol.16
, pp. 1887-1894
-
-
Tsuchiya, T.1
Umeda, M.2
-
8
-
-
0030752647
-
Relationship between exposure to TPA and appearance of transformed cells in MNNG-initiated transformation of BALC/c 3T3 cells
-
DOI 10.1002/(SICI)1097-0215(19971009)73:2<271::AID-IJC18>3.0.CO;2-I
-
Tsuchiya, T. & Umeda, M. (1997). Relationship between exposure to TPA and appearance of transformed cells in MNNG-initiated transformation of BALB/c 3T3 cells. International Journal of Cancer 73, 271-276. (Pubitemid 27448830)
-
(1997)
International Journal of Cancer
, vol.73
, Issue.2
, pp. 271-276
-
-
Tsuchiya, T.1
Umeda, M.2
-
9
-
-
0030722301
-
Improvement of carcinogen detection in the BALB/3T3 cell transformation assay by using a rich basal medium supplemented with low concentration of serum and some growth factors
-
Kajiwara, Y., Ajimi, S., Hosokawa, A. & Maekawa, K. (1997). Improvement of carcinogen detection in the BALB/3T3 cell transformation assay by using a rich basal medium supplemented with low concentration of serum and some growth factors. Mutation Research 393, 81-90.
-
(1997)
Mutation Research
, vol.393
, pp. 81-90
-
-
Kajiwara, Y.1
Ajimi, S.2
Hosokawa, A.3
Maekawa, K.4
-
10
-
-
0038481709
-
Verification of the BALB/c 3T3 cell transformation assay after improvement by using an ITES-medium
-
DOI 10.1016/S0887-2333(03)00050-X
-
Kajiwara, Y. & Ajimi, S. (2003). Verification of the BALB/c 3T3 cell transformation assay after improvement by using an ITES medium. Toxicology in Vitro 17, 489-496. (Pubitemid 36780974)
-
(2003)
Toxicology in Vitro
, vol.17
, Issue.4
, pp. 489-496
-
-
Kajiwara, Y.1
Ajimi, S.2
-
11
-
-
0035010902
-
Improvement of in vitro two-stage transformation assay and determination of the promotional effect of cadmium
-
Fang, M.Z., Kim, D.Y., Lee, H.W. & Cho, M.H. (2001). Improvement of in vitro two-stage transformation assay and determination of the promotional effect of cadmium. Toxicology in Vitro 15, 225-231.
-
(2001)
Toxicology in Vitro
, vol.15
, pp. 225-231
-
-
Fang, M.Z.1
Kim, D.Y.2
Lee, H.W.3
Cho, M.H.4
-
12
-
-
17444388542
-
Inorganic arsenic compounds and methylated metabolites induce morphological transformation in two-stage BALB/c 3T3 cell assay and inhibit metabolic cooperation in V79 cell assay
-
Tsuchiya, T., Tanaka-Kagawa, T., Jinno, H., Tokunaga, H., Sakimoto, K., Ando, M. & Umeda, M. (2005). Inorganic arsenic compounds and methylated metabolites induce morphological transformation in two-stage BALB/c 3T3 cell assay and inhibit metabolic cooperation in V79 cell assay. Toxicological Sciences 84, 344-351.
-
(2005)
Toxicological Sciences
, vol.84
, pp. 344-351
-
-
Tsuchiya, T.1
Tanaka-Kagawa, T.2
Jinno, H.3
Tokunaga, H.4
Sakimoto, K.5
Ando, M.6
Umeda, M.7
-
13
-
-
0032866432
-
An interlaboratory validation study of the improved transformation assay employing Balb/c 3T3 cells: Results of a collaborative study on the two-stage cell transformation assay by the Non-genotoxic Carcinogen Study Group
-
Tsuchiya, T., Umeda, M., Nishiyama, H., Yoshimura, I., Ajimi, S., Asakura, M., Baba, H., Dewa, Y., Ebe, Y., Fushiwaki, Y., Hamada, S., Hamamura, T., Hayashi, M., Iwase, Y., Kajiwara, Y., Kasahara, Y., Kawabata, M., Kitada, E., Kubo, K., Mashiko, K., Miura, D., Mizuhashi, F., Mizuno, F., Nakajima, M., Nakamura, Y., Nobe, N., Oishi, H., Ota, E., Sakai, A., Sato, M., Shimada, S., Sugiyama, T., Takahashi, C., Takeda, Y., Tanaka, N., Toyoizumi, C., Tsutsui, T., Wakuri, S., Yajima, S. & Yajima, N. (1999). An interlaboratory validation study of the improved transformation assay employing Balb/c 3T3 cells: Results of a collaborative study on the two-stage cell transformation assay by the Non-genotoxic Carcinogen Study Group. ATLA 27, 685-702.
-
(1999)
ATLA
, vol.27
, pp. 685-702
-
-
Tsuchiya, T.1
Umeda, M.2
Nishiyama, H.3
Yoshimura, I.4
Ajimi, S.5
Asakura, M.6
Baba, H.7
Dewa, Y.8
Ebe, Y.9
Fushiwaki, Y.10
Hamada, S.11
Hamamura, T.12
Hayashi, M.13
Iwase, Y.14
Kajiwara, Y.15
Kasahara, Y.16
Kawabata, M.17
Kitada, E.18
Kubo, K.19
Mashiko, K.20
Miura, D.21
Mizuhashi, F.22
Mizuno, F.23
Nakajima, M.24
Nakamura, Y.25
Nobe, N.26
Oishi, H.27
Ota, E.28
Sakai, A.29
Sato, M.30
Shimada, S.31
Sugiyama, T.32
Takahashi, C.33
Takeda, Y.34
Tanaka, N.35
Toyoizumi, C.36
Tsutsui, T.37
Wakuri, S.38
Yajima, S.39
Yajima, N.40
more..
-
15
-
-
59849107330
-
Technical modification of the Balb/c 3T3 cell transformation assay: The use of the serum-reduced medium to optimise the practicability of the protocol
-
Hayashi, K., Sasaki, K., Asada, S., Tsuchiya, T., Tanaka, N. & Umeda, M. (2009). Technical modification of the Balb/c 3T3 cell transformation assay: The use of the serum-reduced medium to optimise the practicability of the protocol. ATLA 36, 653-664.
-
(2009)
ATLA
, vol.36
, pp. 653-664
-
-
Hayashi, K.1
Sasaki, K.2
Asada, S.3
Tsuchiya, T.4
Tanaka, N.5
Umeda, M.6
-
16
-
-
0019307710
-
Cell variants showing differential susceptibility to ultraviolet light-induced transformation
-
Kakunaga, T. & Crow, J.D. (1980). Cell variants showing differential susceptibility to ultraviolet light-induced transformation. Science, New York 209, 505-507. (Pubitemid 10022757)
-
(1980)
Science
, vol.209
, Issue.4455
, pp. 505-507
-
-
Kakunaga, T.1
Crow, J.D.2
-
17
-
-
0024850377
-
Cytotoxicity test with simplified crystal violet staining method using microtitre plates and its application to injection drugs
-
DOI 10.1016/0887-2333(89)90039-8
-
Saotome, K., Morita, H. & Umeda, M. (1989). Cytotoxicity test with simplified crystal violet staining method using microtitre plates and its application to injection drugs. Toxicology in Vitro 3, 317-321. (Pubitemid 20019736)
-
(1989)
Toxicology in Vitro
, vol.3
, Issue.4
, pp. 317-321
-
-
Saotome, K.1
Morita, H.2
Umeda, M.3
-
18
-
-
0037182121
-
A new statistical method for evaluation of L5178Y tk+/- Mammalian cell mutation data using microwell method
-
Omori, T., Honma, M., Hayashi, M., Honda, Y. & Yoshimura, I. (2002). A new statistical method for evaluation of L5178Y tk+/- mammalian cell mutation data using microwell method. Mutation Research 517, 199-208.
-
(2002)
Mutation Research
, vol.517
, pp. 199-208
-
-
Omori, T.1
Honma, M.2
Hayashi, M.3
Honda, Y.4
Yoshimura, I.5
-
19
-
-
0037355335
-
A composite statistical procedure for evaluating genotoxicity using cell transformation assay data
-
Nishiyama, H., Tsuchiya, T., Omori, T., Umeda, M. & Yoshimura, I. (2002). A composite statistical procedure for evaluating genotoxicity using cell transformation assay data. Environmetrics 14, 183-192.
-
(2002)
Environmetrics
, vol.14
, pp. 183-192
-
-
Nishiyama, H.1
Tsuchiya, T.2
Omori, T.3
Umeda, M.4
Yoshimura, I.5
-
20
-
-
77956887333
-
Recursive nonparametric testing for dose-response relationship subject to downturn at high dose
-
Simpson, D.G. & Margolin, B. (1986). Recursive nonparametric testing for dose-response relationship subject to downturn at high dose. Biometrika 73, 589-596.
-
(1986)
Biometrika
, vol.73
, pp. 589-596
-
-
Simpson, D.G.1
Margolin, B.2
-
21
-
-
27744493640
-
Detection of initiating as well as promoting activity of chemicals by a novel cell transformation assay using v-Haras-transfected BALB/c3T3 cells (Bhas 42 cells)
-
Asada, S., Sasaki, K., Tanaka, N., Takeda, K., Hayashi, M. & Umeda, M. (2005). Detection of initiating as well as promoting activity of chemicals by a novel cell transformation assay using v-Haras-transfected BALB/c3T3 cells (Bhas 42 cells). Mutation Research 588, 7-21.
-
(2005)
Mutation Research
, vol.588
, pp. 7-21
-
-
Asada, S.1
Sasaki, K.2
Tanaka, N.3
Takeda, K.4
Hayashi, M.5
Umeda, M.6
-
22
-
-
77951659763
-
An interlaboratory collaborative study on a cell transformation assay using Bhas 42 cells
-
Tanaka, N., Sasaki, K., Hayashi, K., Sakai, A., Asada, S., Muramatsu, D., Kuroda, S., Mizuhashi, F., Nagai, M., Suzuki, H., Imamura, T., Asakura, M., Satoh, H., Sakamoto, A., Nakao, R., Hirose, H., Ishii, N. & Umeda, M. (2009). An interlaboratory collaborative study on a cell transformation assay using Bhas 42 cells. AATEX 14, 831-848.
-
(2009)
AATEX
, vol.14
, pp. 831-848
-
-
Tanaka, N.1
Sasaki, K.2
Hayashi, K.3
Sakai, A.4
Asada, S.5
Muramatsu, D.6
Kuroda, S.7
Mizuhashi, F.8
Nagai, M.9
Suzuki, H.10
Imamura, T.11
Asakura, M.12
Satoh, H.13
Sakamoto, A.14
Nakao, R.15
Hirose, H.16
Ishii, N.17
Umeda, M.18
-
23
-
-
0019775477
-
Morphological transformation of C3H/10T 1/2 CL8 cells by alkylating agents
-
DOI 10.1016/0378-4274(81)90001-1
-
Oshiro, Y., Balwierz, P.S. & Molinary, S.V. (1981). Morphological transformation of C3H/10T1/2 CL8 cells by alkylating agents. Toxicology Letters 9, 301-306. (Pubitemid 12201644)
-
(1981)
Toxicology Letters
, vol.9
, Issue.4
, pp. 301-306
-
-
Oshiro, Y.1
Balwierz, P.S.2
Molinary, S.V.3
-
24
-
-
0024509521
-
Study of the ability of phenacetin, acetaminophen, and aspirin to induce cytotoxicity, mutation, and morphological transformation in C3H/10T1/2 clone 8 mouse embryo cells
-
Patierno, S.R., Lehman, N.L., Henderson, B.E. & Landolph, J.R. (1989). Study of the ability of phenacetin, acetaminophen, and aspirin to induce cytotoxicity, mutation, and morphological transformation in C3H/10T1/2 clone 8 mouse embryo cells. Cancer Research 49, 1038-1044.
-
(1989)
Cancer Research
, vol.49
, pp. 1038-1044
-
-
Patierno, S.R.1
Lehman, N.L.2
Henderson, B.E.3
Landolph, J.R.4
-
25
-
-
0023734813
-
Interlaboratory evaluation of the C3H/10T1/2 cell transformation assay
-
Dunkel, V.C., Schechtman, L.M., Tu, A.S., Sivak, A., Lubet, R.A. & Cameron, T.P. (1988). Interlaboratory evaluation of the C3H/10T1/2 cell transformation assay. Environmental & Molecular Mutagenesis 12, 21-31.
-
(1988)
Environmental & Molecular Mutagenesis
, vol.12
, pp. 21-31
-
-
Dunkel, V.C.1
Schechtman, L.M.2
Tu, A.S.3
Sivak, A.4
Lubet, R.A.5
Cameron, T.P.6
-
27
-
-
0019191271
-
Inhibition of induced differentiation of C3H/10T 1/2 clone 8 mouse embryo cells by tumor promoters
-
Mondal, S. & Heidelberger, C. (1980). Inhibition of induced differentiation of C3H/10T1/2 clone 8 mouse embryo cells by tumor promoters. Cancer Research 40, 334-338. (Pubitemid 10140159)
-
(1980)
Cancer Research
, vol.40
, Issue.2
, pp. 334-338
-
-
Mondal, S.1
Heidelberger, C.2
-
28
-
-
0036177896
-
Use of a cell transformation assay with established cell lines, and a metabolic cooperation assay with V79 cells for the detection of tumor promoters: A review
-
Sakai, A., Iwase, Y., Nakamura, Y., Sasaki, K., Tanaka, N. & Umeda, M. (2002). Use of a cell transformation assay with established cell lines, and a metabolic cooperation assay with V79 cells for the detection of tumor promoters: A review. ATLA 30, 33-59.
-
(2002)
ATLA
, vol.30
, pp. 33-59
-
-
Sakai, A.1
Iwase, Y.2
Nakamura, Y.3
Sasaki, K.4
Tanaka, N.5
Umeda, M.6
-
29
-
-
0031419427
-
Orthovanadate, an inhibitor of protein tyrosine phosphatases, acts more potently as a promoter than as an initiator in the BALB/3T3 cell transformation
-
Sakai, A. (1997). Orthovanadate, an inhibitor of protein tyrosine phosphatases, acts more potently as a promoter than as an initiator in the BALB/3T3 cell transformation. Carcinogenesis 18, 1395-1399.
-
(1997)
Carcinogenesis
, vol.18
, pp. 1395-1399
-
-
Sakai, A.1
-
30
-
-
84959814757
-
Tumor-promoting properties of anthralin (1,8,9-anthratriol)
-
Bock, F.G. & Burns, K. (1963). Tumor-promoting properties of anthralin (1,8,9-anthratriol). Journal of the National Cancer Institute 30, 393-398.
-
(1963)
Journal of the National Cancer Institute
, vol.30
, pp. 393-398
-
-
Bock, F.G.1
Burns, K.2
-
31
-
-
0020523825
-
The influence of phenacetin or mechanical perforation on the development of renal pelvic and urinary bladder tumors in FANFT-induced urinary tract carcinogenesis
-
Anderström, C., Johansson, S.L. & von Schultz, L. (1983). The influence of phenacetin or mechanical perforation on the development of renal pelvic and urinary bladder tumors in FANFT-induced urinary tract carcinogenesis. Acta Pathologica, Microbiologica, et Immunologica Scandinavica. Section A, Pathology 91, 373-380.
-
(1983)
Acta Pathologica, Microbiologica, et Immunologica Scandinavica. Section A, Pathology
, vol.91
, pp. 373-380
-
-
Anderström, C.1
Johansson, S.L.2
Von Schultz, L.3
-
32
-
-
0027892520
-
Induction of renal pelvic carcinoma by phenacetin in hydronephrosis- bearing rats of the SD/cShi strain
-
Murai, T., Mori, S., Machino, S., Hosono, M., Takeuchi, Y., Ohara, T., Makino, S., Takeda, R., Hayashi, Y., Iwata, H., Yamamoto, S., Ito, H. & Fukushima, S. (1993). Induction of renal pelvic carcinoma by phenacetin in hydronephrosis-bearing rats of the SD/cShi strain. Cancer Research 53, 4218-4223.
-
(1993)
Cancer Research
, vol.53
, pp. 4218-4223
-
-
Murai, T.1
Mori, S.2
Machino, S.3
Hosono, M.4
Takeuchi, Y.5
Ohara, T.6
Makino, S.7
Takeda, R.8
Hayashi, Y.9
Iwata, H.10
Yamamoto, S.11
Ito, H.12
Fukushima, S.13
-
33
-
-
0028908057
-
Modification by analgesics of lesion development in the urinary tract and various other organs of rats pretreated with dihydroxy-di-N-propylnitrosamine and uracil
-
Shibata, M., Sano, M., Hagiwara, A., Hasegawa, R. & Shirai, T. (1995). Modification by analgesics of lesion development in the urinary tract and various other organs of rats pretreated with dihydroxy-di-N- propylnitrosamine and uracil. Japanese Journal of Cancer Research 86, 160-167.
-
(1995)
Japanese Journal of Cancer Research
, vol.86
, pp. 160-167
-
-
Shibata, M.1
Sano, M.2
Hagiwara, A.3
Hasegawa, R.4
Shirai, T.5
-
34
-
-
0002822405
-
Isolation and characterization of the cocarcinogenic principles from croton oil
-
ed. H. Busch, New York, NY, USA: Academic Press, Inc.
-
Hecker, E. (1971). Isolation and characterization of the cocarcinogenic principles from croton oil. In Methods of Cancer Research, Vol.6 (ed. H. Busch), pp. 439-484. New York, NY, USA: Academic Press, Inc.
-
(1971)
Methods of Cancer Research
, vol.6
, pp. 439-484
-
-
Hecker, E.1
-
35
-
-
0015110691
-
Tumor-promoting activity of phorbol and four diesters of phorbol in mouse skin
-
Baird, W.M. & Boutwell, R.K. (1971). Tumor-promoting activity of phorbol and four diesters of phorbol in mouse skin. Cancer Research 31, 1074-1079.
-
(1971)
Cancer Research
, vol.31
, pp. 1074-1079
-
-
Baird, W.M.1
Boutwell, R.K.2
-
36
-
-
0015405905
-
Systemic promoting action of phorbol in liver and lung carcinogenesis in AKR mice
-
Armuth, V. & Berenblum, I. (1972). Systemic promoting action of phorbol in liver and lung carcinogenesis in AKR mice. Cancer Research 32, 2259-2262.
-
(1972)
Cancer Research
, vol.32
, pp. 2259-2262
-
-
Armuth, V.1
Berenblum, I.2
-
37
-
-
0026090587
-
Cellular retention, cytotoxicity and morphological transformation by vanadium(IV) and vanadium(V) in BALB/3T3 cell lines
-
Sabbioni, E., Pozzi, G., Pintar, A., Casella, L. & Garattini, S. (1991). Cellular retention, cytotoxicity and morphological transformation by vanadium(IV) and vanadium(V) in BALB/3T3 cell lines. Carcinogenesis 12, 47-52.
-
(1991)
Carcinogenesis
, vol.12
, pp. 47-52
-
-
Sabbioni, E.1
Pozzi, G.2
Pintar, A.3
Casella, L.4
Garattini, S.5
-
38
-
-
77951665089
-
-
NIH Research Triangle Park, NC, USA: National Toxicology Program. Available at: Accessed 08.12.09
-
1 mice (Inhalation Studies), NTP TR 507, NIH Publication No. 03-4441, 352pp. Research Triangle Park, NC, USA: National Toxicology Program. Available at: http://ntp.niehs.nih.gov/ntp/htdocs/LT-rpts/tr507.pdf (Accessed 08.12.09).
-
(2002)
1 Mice (Inhalation Studies), NTP TR 507, NIH Publication No. 03-4441
-
-
-
39
-
-
0026352908
-
Effects of transforming growth factor-β on the anchorage-independent growth of murine epithelial JB6 cells
-
Wilder, P.J. & Rizzino, A. (1991). Effects of transforming growth factor-β on the anchorage-independent growth of murine epithelial JB6 cells. Cancer Research 51, 5898-5902.
-
(1991)
Cancer Research
, vol.51
, pp. 5898-5902
-
-
Wilder, P.J.1
Rizzino, A.2
-
40
-
-
0000995727
-
Statistical evaluation of bacterial/mammalian fluctuation tests
-
ed. D.J. Kirkland, Cambridge, UK: Cambridge University Press
-
Robinson, W.D., Green, M.H.L., Cole, J., Healey, M.J.R., Garner, R.C. & Gatehouse, D. (1989). Statistical evaluation of bacterial/mammalian fluctuation tests. In Statistical Evaluation of Mutagenicity Test Data (ed. D.J. Kirkland), 312pp. Cambridge, UK: Cambridge University Press.
-
(1989)
Statistical Evaluation of Mutagenicity Test Data
-
-
Robinson, W.D.1
Green, M.H.L.2
Cole, J.3
Healey, M.J.R.4
Garner, R.C.5
Gatehouse, D.6
|