메뉴 건너뛰기




Volumn 40, Issue 6, 2012, Pages 2668-2682

TDP-43 regulates global translational yield by splicing of exon junction complex component SKAR

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA PRECURSOR; S6 KINASE; S6 KINASE 1; TAR DNA BINDING PROTEIN; UNCLASSIFIED DRUG;

EID: 84859361694     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkr1082     Document Type: Article
Times cited : (75)

References (48)
  • 5
    • 77953890823 scopus 로고    scopus 로고
    • TDP-43 and FUS/TLS: Emerging roles in RNA processing and neurodegeneration
    • Lagier-Tourenne, C., Polymenidou, M. and Cleveland, D.W. (2010) TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration. Hum. Mol. Genet., 19, R46-R64
    • (2010) Hum. Mol. Genet. , vol.19
    • Lagier-Tourenne, C.1    Polymenidou, M.2    Cleveland, D.W.3
  • 6
    • 80052968310 scopus 로고    scopus 로고
    • TDP-43 and FUS/TLS: Cellular functions and implications for neurodegeneration
    • Fiesel, F.C. and Kahle, P.J. (2011) TDP-43 and FUS/TLS: cellular functions and implications for neurodegeneration. FEBS J., 278, 3550-3568
    • (2011) FEBS J. , vol.278 , pp. 3550-3568
    • Fiesel, F.C.1    Kahle, P.J.2
  • 7
    • 0029066110 scopus 로고
    • Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs
    • Ou, S.H., Wu, F., Harrich, D., Garcia-Martinez, L.F. and Gaynor, R.B. (1995) Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs. J. Virol., 69, 3584-3596
    • (1995) J. Virol. , vol.69 , pp. 3584-3596
    • Ou, S.H.1    Wu, F.2    Harrich, D.3    Garcia-Martinez, L.F.4    Gaynor, R.B.5
  • 8
    • 37549025044 scopus 로고    scopus 로고
    • A novel CpG-free vertebrate insulator silences the testis-specific SP-10 gene in somatic tissues: Role for TDP-43 in insulator function
    • Abhyankar, M.M., Urekar, C. and Reddi, P.P. (2007) A novel CpG-free vertebrate insulator silences the testis-specific SP-10 gene in somatic tissues: role for TDP-43 in insulator function. J. Biol. Chem., 282, 36143-36154
    • (2007) J. Biol. Chem. , vol.282 , pp. 36143-36154
    • Abhyankar, M.M.1    Urekar, C.2    Reddi, P.P.3
  • 12
    • 0035965309 scopus 로고    scopus 로고
    • Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43 a novel splicing regulator of CFTR exon 9
    • Buratti, E. and Baralle, F.E. (2001) Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9. J. Biol. Chem., 276, 36337-36343
    • (2001) J. Biol. Chem. , vol.276 , pp. 36337-36343
    • Buratti, E.1    Baralle, F.E.2
  • 13
    • 27744554553 scopus 로고    scopus 로고
    • Depletion of TDP 43 overrides the need for exonic and intronic splicing enhancers in the human apoA-II gene
    • DOI 10.1093/nar/gki897
    • Mercado, P.A., Ayala, Y.M., Romano, M., Buratti, E. and Baralle, F.E. (2005) Depletion of TDP 43 overrides the need for exonic and intronic splicing enhancers in the human apoA-II gene. Nucleic Acids Res., 33, 6000-6010 (Pubitemid 41742619)
    • (2005) Nucleic Acids Research , vol.33 , Issue.18 , pp. 6000-6010
    • Mercado, P.A.1    Ayala, Y.M.2    Romano, M.3    Buratti, E.4    Baralle, F.E.5
  • 14
    • 57649174592 scopus 로고    scopus 로고
    • TDP-43 overexpression enhances exon 7 inclusion during the survival of motor neuron pre-mRNA splicing
    • Bose, J.K., Wang, I.F., Hung, L., Tarn, W.Y. and Shen, C.K. (2008) TDP-43 overexpression enhances exon 7 inclusion during the survival of motor neuron pre-mRNA splicing. J. Biol. Chem., 283, 28852-28859
    • (2008) J. Biol. Chem. , vol.283 , pp. 28852-28859
    • Bose, J.K.1    Wang, I.F.2    Hung, L.3    Tarn, W.Y.4    Shen, C.K.5
  • 18
    • 77958604956 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis-associated proteins TDP-43 and FUS/TLS function in a common biochemical complex to co-regulate HDAC6 mRNA
    • Kim, S.H., Shanware, N.P., Bowler, M.J. and Tibbetts, R.S. (2010) Amyotrophic lateral sclerosis-associated proteins TDP-43 and FUS/TLS function in a common biochemical complex to co-regulate HDAC6 mRNA. J. Biol. Chem., 285, 34097-34105
    • (2010) J. Biol. Chem. , vol.285 , pp. 34097-34105
    • Kim, S.H.1    Shanware, N.P.2    Bowler, M.J.3    Tibbetts, R.S.4
  • 19
    • 77958012134 scopus 로고    scopus 로고
    • Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism
    • Chiang, P.M., Ling, J., Jeong, Y.H., Price, D.L., Aja, S.M. and Wong, P.C. (2010) Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism. Proc. Natl Acad. Sci USA, 107, 16320-16324
    • (2010) Proc. Natl Acad. Sci USA , Issue.107 , pp. 16320-16324
    • Chiang, P.M.1    Ling, J.2    Jeong, Y.H.3    Price, D.L.4    Aja, S.M.5    Wong, P.C.6
  • 25
    • 77956850818 scopus 로고    scopus 로고
    • TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
    • Mackenzie, I.R., Rademakers, R. and Neumann, M. (2010) TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia. Lancet Neurol., 9, 995-1007
    • (2010) Lancet Neurol. , vol.9 , pp. 995-1007
    • MacKenzie, I.R.1    Rademakers, R.2    Neumann, M.3
  • 27
    • 41949101770 scopus 로고    scopus 로고
    • SKAR Links Pre-mRNA Splicing to mTOR/S6K1-Mediated Enhanced Translation Efficiency of Spliced mRNAs
    • DOI 10.1016/j.cell.2008.02.031, PII S0092867408002821
    • Ma, X.M., Yoon, S.O., Richardson, C.J., Julich, K. and Blenis, J. (2008) SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs. Cell, 133, 303-313 (Pubitemid 351508301)
    • (2008) Cell , vol.133 , Issue.2 , pp. 303-313
    • Ma, X.M.1    Yoon, S.-O.2    Richardson, C.J.3    Julich, K.4    Blenis, J.5
  • 28
    • 0035794665 scopus 로고    scopus 로고
    • Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping
    • DOI 10.1093/emboj/20.7.1774
    • Buratti, E., Dork, T., Zuccato, E., Pagani, F., Romano, M. and Baralle, F.E. (2001) Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping. EMBO J., 20, 1774-1784 (Pubitemid 32299413)
    • (2001) EMBO Journal , vol.20 , Issue.7 , pp. 1774-1784
    • Buratti, E.1    Dork, T.2    Zuccato, E.3    Pagani, F.4    Romano, M.5    Baralle, F.E.6
  • 29
    • 0037406116 scopus 로고    scopus 로고
    • A quantitative analysis of intron effects on mammalian gene expression
    • DOI 10.1261/rna.5250403
    • Nott, A., Meislin, S.H. and Moore, M.J. (2003) A quantitative analysis of intron effects on mammalian gene expression. RNA, 9, 607-617 (Pubitemid 36505458)
    • (2003) RNA , vol.9 , Issue.5 , pp. 607-617
    • Nott, A.1    Meislin, S.H.2    Moore, M.J.3
  • 32
    • 40749162839 scopus 로고    scopus 로고
    • Estimation and assessment of raw copy numbers at the single locus level
    • DOI 10.1093/bioinformatics/btn016
    • Bengtsson, H., Irizarry, R., Carvalho, B. and Speed, T.P. (2008) Estimation and assessment of raw copy numbers at the single locus level. Bioinformatics, 24, 759-767 (Pubitemid 351386913)
    • (2008) Bioinformatics , vol.24 , Issue.6 , pp. 759-767
    • Bengtsson, H.1    Irizarry, R.2    Carvalho, B.3    Speed, T.P.4
  • 33
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini, Y. and Hochberg, Y. (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Stat. Soc. B, 57, 289-300
    • (1995) J. R. Stat. Soc. B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 34
    • 62349102835 scopus 로고    scopus 로고
    • GenomeGraphs: Integrated genomic data visualization with R
    • Durinck, S., Bullard, J., Spellman, P.T. and Dudoit, S. (2009) GenomeGraphs: integrated genomic data visualization with R. BMC Bioinform., 10, 2
    • (2009) BMC Bioinform. , vol.10 , pp. 2
    • Durinck, S.1    Bullard, J.2    Spellman, P.T.3    Dudoit, S.4
  • 35
    • 24044522270 scopus 로고    scopus 로고
    • BioMart and Bioconductor: A powerful link between biological databases and microarray data analysis
    • DOI 10.1093/bioinformatics/bti525
    • Durinck, S., Moreau, Y., Kasprzyk, A., Davis, S., De Moor, B., Brazma, A. and Huber, W. (2005) BioMart and bioconductor: a powerful link between biological databases and microarray data analysis. Bioinformatics, 21, 3439-3440 (Pubitemid 41222455)
    • (2005) Bioinformatics , vol.21 , Issue.16 , pp. 3439-3440
    • Durinck, S.1    Moreau, Y.2    Kasprzyk, A.3    Davis, S.4    De Moor, B.5    Brazma, A.6    Huber, W.7
  • 37
    • 27844514227 scopus 로고    scopus 로고
    • TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: An important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing
    • DOI 10.1074/jbc.M505557200
    • Buratti, E., Brindisi, A., Giombi, M., Tisminetzky, S., Ayala, Y.M. and Baralle, F.E. (2005) TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: an important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing. J. Biol. Chem., 280, 37572-37584 (Pubitemid 41642366)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.45 , pp. 37572-37584
    • Buratti, E.1    Brindisi, A.2    Giombi, M.3    Tisminetzky, S.4    Ayala, Y.M.5    Baralle, F.E.6
  • 38
    • 72849106592 scopus 로고    scopus 로고
    • RNA processing and its regulation: Global insights into biological networks
    • Licatalosi, D.D. and Darnell, R.B. (2010) RNA processing and its regulation: global insights into biological networks. Nat. Rev. Genet., 11, 75-87
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 75-87
    • Licatalosi, D.D.1    Darnell, R.B.2
  • 39
    • 0038751901 scopus 로고    scopus 로고
    • Identification of a novel protein, PDIP38, that interacts with the p50 subunit of DNA polymerase δ and proliferating cell nuclear antigen
    • DOI 10.1074/jbc.M208694200
    • Liu, L., Rodriguez-Belmonte, E.M., Mazloum, N., Xie, B. and Lee, M.Y. (2003) Identification of a novel protein, PDIP38, that interacts with the p50 subunit of DNA polymerase delta and proliferating cell nuclear antigen. J. Biol. Chem., 278, 10041-10047 (Pubitemid 36800258)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.12 , pp. 10041-10047
    • Liu, L.1    Rodriguez-Belmonte, E.M.2    Mazloum, N.3    Xie, B.4    Lee, M.Y.W.T.5
  • 40
    • 4644303065 scopus 로고    scopus 로고
    • SKAR is a specific target of S6 kinase 1 in cell growth control
    • DOI 10.1016/j.cub.2004.08.061, PII S0960982204006530
    • Richardson, C.J., Broenstrup, M., Fingar, D.C., Julich, K., Ballif, B.A., Gygi, S. and Blenis, J. (2004) SKAR is a specific target of S6 kinase 1 in cell growth control. Curr. Biol., 14, 1540-1549 (Pubitemid 39290051)
    • (2004) Current Biology , vol.14 , Issue.17 , pp. 1540-1549
    • Richardson, C.J.1    Broenstrup, M.2    Fingar, D.C.3    Julich, K.4    Ballif, B.A.5    Gygi, S.6    Blenis, J.7
  • 42
    • 69449101422 scopus 로고    scopus 로고
    • Functional role for senataxin, defective in ataxia oculomotor apraxia type 2, in transcriptional regulation
    • Suraweera, A., Lim, Y., Woods, R., Birrell, G.W., Nasim, T., Becherel, O.J. and Lavin, M.F. (2009) Functional role for senataxin, defective in ataxia oculomotor apraxia type 2, in transcriptional regulation. Hum. Mol. Genet., 18, 3384-3396
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 3384-3396
    • Suraweera, A.1    Lim, Y.2    Woods, R.3    Birrell, G.W.4    Nasim, T.5    Becherel, O.J.6    Lavin, M.F.7
  • 43
    • 34250305505 scopus 로고    scopus 로고
    • Elongator complex: How many roles does it play?
    • DOI 10.1016/j.ceb.2007.04.005, PII S0955067407000579, Nucleus and Gene Expression
    • Svejstrup, J.Q. (2007) Elongator complex: how many roles does it play? Curr. Opin. Cell Biol., 19, 331-336 (Pubitemid 46908882)
    • (2007) Current Opinion in Cell Biology , vol.19 , Issue.3 , pp. 331-336
    • Svejstrup, J.Q.1
  • 45
    • 77949878273 scopus 로고    scopus 로고
    • TDP-43 is a developmentally regulated protein essential for early embryonic development
    • Sephton, C.F., Good, S.K., Atkin, S., Dewey, C.M., Mayer, P. III, Herz, J. and Yu, G. (2010) TDP-43 is a developmentally regulated protein essential for early embryonic development. J. Biol. Chem., 285, 6826-6834
    • (2010) J. Biol. Chem. , vol.285 , pp. 6826-6834
    • Sephton, C.F.1    Good, S.K.2    Atkin, S.3    Dewey, C.M.4    Mayer Iii., P.5    Herz, J.6    Yu, G.7
  • 46
    • 74749107048 scopus 로고    scopus 로고
    • TDP-43, a neuro-pathosignature factor, is essential for early mouse embryogenesis
    • Wu, L.S., Cheng, W.C., Hou, S.C., Yan, Y.T., Jiang, S.T. and Shen, C.K. (2010) TDP-43, a neuro-pathosignature factor, is essential for early mouse embryogenesis. Genesis, 48, 56-62
    • (2010) Genesis , vol.48 , pp. 56-62
    • Wu, L.S.1    Cheng, W.C.2    Hou, S.C.3    Yan, Y.T.4    Jiang, S.T.5    Shen, C.K.6
  • 47
    • 41149151929 scopus 로고    scopus 로고
    • SnapShot: The splicing regulatory machinery
    • e191
    • Gabut, M., Chaudhry, S. and Blencowe, B.J. (2008) SnapShot: the splicing regulatory machinery. Cell, 133, 192 e191
    • (2008) Cell , vol.133 , pp. 192
    • Gabut, M.1    Chaudhry, S.2    Blencowe, B.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.