Hexavalent chromium induced ROS formation, Akt, NF-κB, and MAPK activation, and TNF-α and IL-1α production in keratinocytes

Toxicology Letters

Volumn 198, Issue 2, 2010, Pages 216-224

  Wang, Bour Jr ^a   Sheu, Hamm Ming ^a   Guo, Yue Liang ^b   Lee, Yu Hsuan ^a   Lai, Ching Shu ^a,c   Pan, Min Hsiung ^c   Wang, Ying Jan ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c NATIONAL KAOHSIUNG UNIVERSITY OF APPLIED SCIENCES   (Taiwan)

Author keywords

Chromium hypersensitivity; Hexavalent chromium; Mitogen activated protein kinase; Nuclear factor B; Reactive oxygen species; Tumor necrosis factor

Indexed keywords

CHROMIUM DERIVATIVE; HEXALENT CHROMIUM; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CELL VIABILITY; CONTACT ALLERGY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVATION; FEMALE; GUINEA PIG; HUMAN; HUMAN CELL; KERATINOCYTE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; CELL LINE; CELL SURVIVAL; CHROMIUM; CYTOKINES; DERMATITIS, CONTACT; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GUINEA PIGS; HUMANS; HYDROGEN PEROXIDE; INTERLEUKIN-1; KERATINOCYTES; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SKIN; TUMOR NECROSIS FACTOR-ALPHA;

CAVIA;

EID: 77955921323     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2010.06.024     Document Type: Article

References (57)

1. Anderson R.A. Chromium in the prevention and control of diabetes. Diabetes Metab. 2000, 26:22-27.
2. Avnstorp C. Prevalence of cement eczema in Denmark before and since addition of ferrous sulfate to Danish cement. Acta Derm. Venereol. 1989, 69:151-155.
3. Bagchi D., Bagchi M., Stohs S.J. Chromium (VI)-induced oxidative stress, apoptotic cell death and modulation of p53 tumor suppressor gene. Mol. Cell. Biochem. 2001, 222:149-158.
4. Beaver L.M., Stemmy E.J., Constant S.L., Schwartz A., Little L.G., Gigley J.P., Chun G., Sugden K.D., Ceryak S.M., Patierno S.R. Lung injury, inflammation and Akt signaling following inhalation of particulate hexavalent chromium. Toxicol. Appl. Pharmacol. 2009, 235:47-56.
5. Beissert S., Cavazzana I., Mascia F., Meroni P., Pastore S., Tessari G., Girolomoni G. Mechanisms of immune-mediated skin diseases: an overview. Clin. Exp. Rheumatol. 2006, 24:S1-6.
6. Boukamp P., Petrussevska R.T., Breitkreutz D., Hornung J., Markham A., Fusenig N.E. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J. Cell Biol. 1988, 106:761-771.
7. Bowie A., O'Neill L.A. Oxidative stress and nuclear factor-kappaB activation: a reassessment of the evidence in the light of recent discoveries. Biochem. Pharmacol. 2000, 59:13-23.
8. Bradberry S.M., Vale J.A. Therapeutic review: is ascorbic acid of value in chromium poisoning and chromium dermatitis?. J. Toxicol. Clin. Toxicol. 1999, 37:195-200.
9. Chuang S.M., Liou G.Y., Yang J.L. Activation of JNK, p38 and ERK mitogen-activated protein kinases by chromium(VI) is mediated through oxidative stress but does not affect cytotoxicity. Carcinogenesis 2000, 21:1491-1500.
10. Cohen M.D., Kargacin B., Klein C.B., Costa M. Mechanisms of chromium carcinogenicity and toxicity. Crit. Rev. Toxicol. 1993, 23:255-281.
11. Corsini E., Galli C.L. Cytokines and irritant contact dermatitis. Toxicol. Lett. 1998, 102/103:277-282.
12. Corsini E., Galli C.L. Epidermal cytokines in experimental contact dermatitis. Toxicology 2000, 142:203-211.
13. Cumberbatch M., Dearman R.J., Groves R.W., Antonopoulos C., Kimber I. Differential regulation of epidermal langerhans cell migration by interleukins (IL)-1alpha and IL-1beta during irritant- and allergen-induced cutaneous immune responses. Toxicol. Appl. Pharmacol. 2002, 182:126-135.
14. Curtis A., Morton J., Balafa C., MacNeil S., Gawkrodger D.J., Warren N.D., Evans G.S. The effects of nickel and chromium on human keratinocytes: differences in viability, cell associated metal and IL-1alpha release. Toxicol. In Vitro 2007, 21:809-819.
15. Dumitru C.D., Ceci J.D., Tsatsanis C., Kontoyiannis D., Stamatakis K., Lin J.H., Patriotis C., Jenkins N.A., Copeland N.G., Kollias G., Tsichlis P.N. TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway. Cell 2000, 103:1071-1083.
16. Enk A.H., Katz S.I. Early molecular events in the induction phase of contact sensitivity. Proc. Natl. Acad. Sci. U.S.A. 1992, 89:1398-1402.
17. Faurschou A., Gniadecki R. TNF-alpha stimulates Akt by a distinct aPKC-dependent pathway in premalignant keratinocytes. Exp. Dermatol. 2008, 17:992-997.
18. Feldmeyer L., Keller M., Niklaus G., Hohl D., Werner S., Beer H.D. The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes. Curr. Biol. 2007, 17:1140-1145.
19. Fregert S., Gruvberger B., Sandahl E. Reduction of chromate in cement by iron sulfate. Contact Dermatitis 1979, 5:39-42.
20. Frosch P.J., Menne T., Lepoittevin J.P. Contact Dermatitis 2006, Springer-Verlag, Berlin/Heidelberg. 4th ed.
21. Gaestel M., Kotlyarov A., Kracht M. Targeting innate immunity protein kinase signalling in inflammation. Nat. Rev. Drug Discov. 2009, 8:480-499.
22. Goh C.L., Gan S.L., Ngui S.J. Occupational dermatitis in a prefabrication construction factory. Contact Dermatitis 1986, 15:235-240.
23. Gueniche A., Viac J., Lizard G., Charveron M., Schmitt D. Effect of various metals on intercellular adhesion molecule-1 expression and tumour necrosis factor alpha production by normal human keratinocytes. Arch. Dermatol. Res. 1994, 286:466-470.
24. Guo Y.L., Wang B.J., Yeh K.C., Wang J.C., Kao H.H., Wang M.T., Shih H.C., Chen C.J. Dermatoses in cement workers in southern Taiwan. Contact Dermatitis 1999, 40:1-7.
25. Hartupee J., Li X., Hamilton T. Interleukin 1alpha-induced NFkappaB activation and chemokine mRNA stabilization diverge at IRAK1. J. Biol. Chem. 2008, 283:15689-15693.
26. Hertel R.F. Sources of Exposure and Biological Effects of Chromium 1986, IARC Sci Publ., pp. 63-77.
27. Jamaluddin M., Wang S., Boldogh I., Tian B., Brasier A.R. TNF-alpha-induced NF-kappaB/RelA Ser(276) phosphorylation and enhanceosome formation is mediated by an ROS-dependent PKAc pathway. Cell Signal 2007, 19:1419-1433.
28. Kawai Y., Kubota E., Okabe E. Reactive oxygen species participation in experimentally induced arthritis of the temporomandibular joint in rats. J. Dent. Res. 2000, 79:1489-1495.
29. Kim G., Yurkow E.J. Chromium induces a persistent activation of mitogen-activated protein kinases by a redox-sensitive mechanism in H4 rat hepatoma cells. Cancer Res. 1996, 56:2045-2051.
30. Kondo S., Sauder D.N. Epidermal cytokines in allergic contact dermatitis. J. Am. Acad. Dermatol. 1995, 33:786-800.
31. Lai C.S., Li S., Chai C.Y., Lo C.Y., Ho C.T., Wang Y.J., Pan M.H. Inhibitory effect of citrus 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone on 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumor promotion in mice. Carcinogenesis 2007, 28:2581-2588.
32. Lampert I.A. Expression of HLA-DR (Ia like) antigen on epidermal keratinocytes in human dermatoses. Clin. Exp. Immunol. 1984, 57:93-100.
33. Langard S. One hundred years of chromium and cancer: a review of epidemiological evidence and selected case reports. Am. J. Ind. Med. 1990, 17:189-215.
34. Leonard S.S., Roberts J.R., Antonini J.M., Castranova V., Shi X. PbCrO4 mediates cellular responses via reactive oxygen species. Mol. Cell. Biochem. 2004, 255:171-179.
35. Little M.C., Gawkrodger D.J., MacNeil S. Chromium- and nickel-induced cytotoxicity in normal and transformed human keratinocytes: an investigation of pharmacological approaches to the prevention of Cr(VI)-induced cytotoxicity. Br. J. Dermatol. 1996, 134:199-207.
36. Little M.C., Metcalfe R.A., Haycock J.W., Healy J., Gawkrodger D.J., Mac Neil S. The participation of proliferative keratinocytes in the preimmune response to sensitizing agents. Br. J. Dermatol. 1998, 138:45-56.
37. Luger T.A., Stadler B.M., Katz S.I., Oppenheim J.J. Epidermal cell (keratinocyte)-derived thymocyte-activating factor (ETAF). J. Immunol. 1981, 127:1493-1498.
38. Marks J.G., Elsner P., Deleo V.A. Contact and Occupational Dermatology 2002, Mosby Inc., Missouri.
39. McKenzie R.C., Sauder D.N. The role of keratinocyte cytokines in inflammation and immunity. J. Invest. Dermatol. 1990, 95:105S-107S.
40. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983, 65:55-63.
41. Nielsen N.H., Menne T. Allergic contact sensitization in an unselected Danish population. The Glostrup Allergy Study, Denmark. Acta Derm. Venereol. 1992, 72:456-460.
42. O'Neill L.A. The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress. Immunol. Rev. 2008, 226:10-18.
43. Pick E., Keisari Y. A simple colorimetric method for the measurement of hydrogen peroxide produced by cells in culture. J. Immunol. Methods 1980, 38:161-170.
44. Ringwood L., Li L. The involvement of the interleukin-1 receptor-associated kinases (IRAKs) in cellular signaling networks controlling inflammation. Cytokine 2008, 42:1-7.
45. Rommel C., Camps M., Ji H. PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and beyond?. Nat. Rev. Immunol. 2007, 7:191-201.
46. Sen C.K., Packer L. Antioxidant and redox regulation of gene transcription. FASEB J. 1996, 10:709-720.
47. Shelnutt S.R., Goad P., Belsito D.V. Dermatological toxicity of hexavalent chromium. Crit. Rev. Toxicol. 2007, 37:375-387.
48. Smith H.R., Basketter D.A., McFadden J.P. Irritant dermatitis, irritancy and its role in allergic contact dermatitis. Clin. Exp. Dermatol. 2002, 27:138-146.
49. Sze C.I., Su M., Pugazhenthi S., Jambal P., Hsu L.J., Heath J., Schultz L., Chang N.S. Down-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's disease. J. Biol. Chem. 2004, 279:30498-30506.
50. Uter W., Ruhl R., Pfahlberg A., Geier J., Schnuch A., Gefeller O. Contact allergy in construction workers: results of a multifactorial analysis. Ann. Occup. Hyg. 2004, 48:21-27.
51. Valko M., Morris H., Cronin M.T. Metals, toxicity and oxidative stress. Curr. Med. Chem. 2005, 12:1161-1208.
52. Van Hoogstraten I.M., de Groot J., Boden D., von Blomberg B.M., Kraal G., Scheper R.J. Development of a concomitant nickel and chromium sensitization model in the guinea pig. Int. Arch. Allergy Immunol. 1992, 97:258-266.
53. Wang B.J., Guo Y.L., Chang H.Y., Sheu H.M., Pan M.H., Lee Y.H., Wang Y.J. N-acetylcysteine inhibits chromium hypersensitivity in coadjuvant chromium-sensitized albino guinea pigs by suppressing the effects of reactive oxygen species. Exp. Dermatol. 2010.
54. Winyard P.G., Blake D.R. Antioxidants, redox-regulated transcription factors, and inflammation. Adv. Pharmacol. 1997, 38:403-421.
55. Ye J., Shi X. Gene expression profile in response to chromium-induced cell stress in A549 cells. Mol. Cell. Biochem. 2001, 222:189-197.
56. Ye J., Zhang X., Young H.A., Mao Y., Shi X. Chromium(VI)-induced nuclear factor-kappa B activation in intact cells via free radical reactions. Carcinogenesis 1995, 16:2401-2405.
57. Young C.N., Koepke J.I., Terlecky L.J., Borkin M.S., Boyd Savoy L., Terlecky S.R. Reactive oxygen species in tumor necrosis factor-alpha-activated primary human keratinocytes: implications for psoriasis and inflammatory skin disease. J. Invest. Dermatol. 2008, 128:2606-2614.