Activation of both nuclear factor of activated T cells and inhibitor of nuclear factor-κB kinase β-subunit-/nuclear factor-κB is critical for cyclooxygenase-2 induction by benzo[a]pyrene in human bronchial epithelial cells

Cancer Science

Volumn 98, Issue 9, 2007, Pages 1323-1329

  Ding, Jin ^a   Wu, Kangjian ^a   Zhang, Dongyun ^a   Luo, Wenjing ^a   Li, Jingxia ^a   Ouyang, Weiming ^a   Song, Lun ^a   Huang, Chuanshu ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZO[A]PYRENE; CYCLOOXYGENASE 2; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR NFAT;

ARTICLE; BINDING SITE; BRONCHUS MUCOSA; CANCER CELL CULTURE; CARCINOGENESIS; CONTROLLED STUDY; DNA FLANKING REGION; EMBRYO; EPITHELIUM CELL; FIBROBLAST; GENE MUTATION; HUMAN; HUMAN CELL; LUNG CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; UPREGULATION;

AMINO ACID SEQUENCE; BENZO(A)PYRENE; BRONCHI; CELL LINE, TRANSFORMED; CYCLOOXYGENASE 2; ENZYME INDUCTION; HUMANS; I-KAPPA B KINASE; MOLECULAR SEQUENCE DATA; NF-KAPPA B; NFATC TRANSCRIPTION FACTORS; PROTEIN SUBUNITS; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION;

EID: 34547791389     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2007.00530.x     Document Type: Article

References (41)

1. Tammemagi MC, McLaughlin JR, Mullen JBM et al. A study of smoking, p53 tumor suppressor gene alterations and non-small cell lung cancer. Ann Epidemiol 2000; 10: 176-85.
2. Zheng Z, Bepler G, Cantor A, Haura EB. Small tumor size and limited smoking history predicts activated epidermal growth factor receptor in early-stage non-small cell lung cancer. Chest 2005; 128: 308-16.
3. Jackman DM, Johnson BE. Small-cell lung cancer. Lancet 2005; 366: 1385-96.
4. Tsuji PA, Walle T. Inhibition of benzo[a]pyrene-activating enzymes and DNA-binding in human bronchial epithelial BEAS-2B cells by methoxylated flavonoids. Carcinogenesis 2006; 27: 1579-85.
5. Senthilnathan P, Padmavathi R, Banu SM, Sakthisekaran D. Enhancement of antitumor effect of paclitaxel in combination with immunomodulatory Withania somnifera on benzo(a)pyrene induced experimental lung cancer. Chem Biol Interact 2006; 159: 180-5.
6. Selvendiran K, Prince Vijeya Singh J, Sakthisekaran D. In vivo effect of piperine on serum and tissue glycoprotein levels in benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice. Pulm Pharmacol Ther 2006; 19: 107-11.
7. Cosman M, de los Santos C, Fiala R et al. Solution conformation major adduct between carcinogen (+)-anti-benzo[a]pyrene diol epoxide DNA. Proc Natl Acad Sci USA 1992; 89: 1914-18.
8. Slaga T. Inhibition of skin tumor initiation, promotion, and progression by antioxidants and related compounds. Crit Rev Food Sci Nutr 1995; 35: 51-7.
9. Gasparini G, Longo R, Sarmiento R, Morabito A. Inhibitors of cyclo-oxygenase 2: A new class of anticancer agents? Lancet Oncol 2003; 4: 605-15.
10. Subbaramaiah K, Dannenberg AJ. Cyclooxygenase 2: A molecular target for cancer prevention and treatment. Trends Pharmacol Sci 2003; 24: 96-102.
11. Gorgoni B, Caivano M, Arizmendi C, Poli V. The transcription factor C/EBPβ is essential for inducible expression of the cox-2 gene in macrophages but not in fibroblasts. J Biol Chem 2001; 276: 40 769-77.
12. Hogan PG, Chen L, Nardone J, Rao A. Transcriptional regulation by calcium, calcineurin, and NFAT. Genes Dev 2003; 17: 2205-32.
13. Riedl K, Krysan K, Pold M et al. Multifaceted roles of cyclooxygenase-2 in lung cancer. Drug Resist Updat 2004; 7: 169-84.
14. Chen W-S, Wei S-J, Liu JM, Hsiao M, Kou-Lin J, Yang WK. Tumor invasiveness and liver metastasis of colon cancer cells correlated with cyclooxygenase-2 (COX-2) expression and inhibited by a COX-2-selective inhibitor, etodolac. Int J Cancer 2001; 91: 894-9.
15. Subbaramaiah K, Bulic P, Lin Y, Dannenberg AJ, Pasco DS. Development and use of a gene promoter-based screen to identify novel inhibitors of cyclooxygenase-2 transcription. J Biomol Screen 2001; 6: 101-10.
16. Yan Y, Li J, Ouyang W et al. NFAT3 is specifically required for TNF-alpha-induced cyclooxygenase-2 (COX-2) expression and transformation of C141 cells. J Cell Sci 2006; 119: 2985-94.
17. Huang Y, Davidson G, Li J et al. Activation of nuclear factor-κB and not activator protein-1 in cellular response to nickel compounds. Environ Health Perspec Suppl 2002; 110 (Suppl. 5): 835-9.
18. Craig DA, Raymond TJ, Eric AH, Joseph AF, Benjamin FT, James HR. Transformed human bronchial epithelial cells (beas-2b) alter the growth and morphology of normal human bronchial epithelial cells in vitro. Cell Biol Toxicol 1990; 6: 379-98.
19. Weng M-W, Hsiao Y-M, Chen C-J, Wang J-P, Chen W-C, Ko J-L. Benzo[a]pyrene diol epoxide up-regulates COX-2 expression through NF-κB in rat astrocytes. Toxicol Lett 2004; 151: 345-55.
20. Almahmeed T, Boyle JO, Cohen EG et al. Benzo[a]pyrene phenols are more potent inducers of CYP1A1, CYP1B1 and COX-2 than benzo[a]pyrene glucuronides in cell lines derived from the human aerodigestive tract. Carcinogenesis 2004; 25: 793-9.
21. Eckstein LA, Van Quill KR, Bui SK, Uusitalo MS, O'Brien JM. Cyclosporin a inhibits calcineurin/nuclear factor of activated T-cells signaling and induces apoptosis in retinoblastoma cells. Invest Ophthalmol Vis Sci 2005; 46: 782-90.
22. Yiu GK, Toker AK. NFAT induces breast cancer cell invasion by promoting the induction of cyclooxygenase-2. J Biol Chem 2006; 281: 12210-17.
23. Duque J, Fresno M, Iniguez MA. Expression and function of the nuclear factor of activated T cells in colon carcinoma cells: Involvement in regulation of cyclooxygenase-2. J Biol Chem 2005; 280: 8686-93.
24. Jimenez JL, Iniguez MA, Munoz-Fernandez MA, Fresno M. Effect of phosphodiesterase 4 inhibitors on NFAT-dependent cyclooxygenase-2 expression in human T lymphocytes. Cell Signal 2004; 16: 1363.
25. Ouyang W, Ma Q, Li J et al. Benzo[a]pyrene diol-epoxide (B[a]PDE) upregulates COX-2 expression through MAPKs/AP-1 and IKKbeta/NF-kappaB in mouse epidermal C141 cells. Mol Carcinog 2007; 46: 32-41.
26. Kojima MMT, Izuhara K, Uchiyama A, Matsunari Y, Katano M, Tanaka M. Lipopolysaccharide increases cyclo-oxygenase-2 expression in a colon carcinoma cell line through nuclear factor-kappa B activation. Oncogene 2000; 19: 1225-31.
27. Schmedtje JF Jr, Ji Y-S, Liu WL, DuBois RN, Runge MS. Hypoxia induces cyclooxygenase-2 via the NF-κB p65 transcription factor in human vascular endothelial cells. J Biol Chem 1997; 272: 601-8.
28. Sheng H, Shao J, Washington MK, DuBois RN. Prostaglandin E2 increases growth and motility of colorectal carcinoma cells. J Biol Chem 2001; 276: 18 075-81.
29. Smith WL, Garavito RM, DeWitt DL. Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2. J Biol Chem 1996; 271: 33 157-60.
30. Trifan OC, Hla T. Cyclooxygenase-2 modulates cellular growth and promotes tumorigenesis. J Cell Mol Med 2003; 7: 207-22.
31. El-Bayoumy K, Iatropoulos M, Amin S, Hoffmann D, Wynder EL. Increased expression of cyclooxygenase-2 in rat lung tumors induced by the tobacco-specific nitrosamine 4-(methylnitrosamino)-4-(3-pyridyl)-1-butanone: The impact a high-fat diet. Cancer Res 1999; 59: 1400-3.
32. Khuri FR, Wu H, Lee JJ et al. Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer. Clin Cancer Res 2001; 7: 861-7.
33. Castelao JE, Bart RD, DiPerna CA, Sievers EM, Bremner RM. Lung cancer and cyclooxygenase-2. Ann Thorac Surg 2003; 76: 1327-35.
34. Ding J, Zhang X, Li J et al. Nickel compounds render anti-apoptotic effect to human bronchial epithelial Beas-2B cells by induction of COX-2 through IKKβ/p65-dependent, and IKKα- and p50-independent pathways. J Biol Chem 2006; 281: 39 022-32.
35. Ding J, Li J, Xue C et al. Cyclooxygenase-2 induction by arsenite is through a nuclear factor of activated T-cell-dependent pathway and plays an antiapoptotic role in Beas-2B cells. J Biol Chem 2006; 281: 24 405-13.
36. Iniguez MA, Martinez-Martinez S, Punzon C, Redondo JM, Fresno M. An essential role of the nuclear factor of activated T cells in the regulation of the expression of the cyclooxygenase-2 gene in human T lymphocytes. J Biol Chem 2000; 275: 23 627-35.
37. de Gregorio R, Iniguez MA, Fresno M, Alemany S. Cot kinase induces cyclooxygenase-2 expression in T cells through activation of the nuclear factor of activated T cells. J Biol Chem 2001; 276: 27 003-9.
38. Chun K-S, Surh Y-J. Signal transduction pathways regulating cyclooxygenase-2 expression: Potential molecular targets for chemoprevention. Biochem Pharmacol 2004; 68: 1089-100.
39. D'Acquisto F, Iuvone T, Rombola L, Sautebin L, Di Rosa M, Carnuccio R. Involvement of NF-κ B in the regulation of cyclooxygenase-2 protein expression in LPS-stimulated J774 macrophages. FEBS Lett 1997; 418: 175-8.
40. Sugimoto T, Haneda M, Sawano H et al. Endothelin-1 induces cyclooxygenase-2 expression via nuclear factor of activated T-cell transcription factor in glomerular mesangial cells. J Am Soc Nephrol 2001; 12: 1359-68.
41. Serfling E, Berberich-Siebelt F, Avots A et al. NFAT and NF-κB factors-the distant relatives. Int J Biochem Cell Biol 2004; 36: 1166-70.