메뉴 건너뛰기




Volumn 19, Issue 1, 2012, Pages 31-37

Two generation reproductive and developmental toxicity following subchronic exposure of pubescent male mice to di(2-ethylhexyl)phthalate

Author keywords

DEHP; Male mediated effects; Mice; Progeny; Spermatozoa

Indexed keywords

PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER;

EID: 84859343405     PISSN: 12321966     EISSN: 18982263     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (24)

References (67)
  • 1
    • 79954989659 scopus 로고    scopus 로고
    • Potential risk of exposure to selected xenobiotic residues and their fate in the food chain. Part 1: Classification of xenobiotics
    • Iovdijova A, Bencko V. Potential risk of exposure to selected xenobiotic residues and their fate in the food chain. Part 1: Classification of xenobiotics. Ann Agric Environ Med. 2010; 17: 183-192.
    • (2010) Ann Agric Environ Med , vol.17 , pp. 183-192
    • Iovdijova, A.1    Bencko, V.2
  • 3
    • 0242352031 scopus 로고
    • ATSDR, Agency for Toxic Substances and Disease Registry, United States Public Health Service, Atlanta (GA)
    • ATSDR. Toxicological profile for di(2-ethylhexyl)phthalate. Agency for Toxic Substances and Disease Registry, United States Public Health Service, Atlanta (GA) 1989.
    • (1989) Toxicological profile for di(2-ethylhexyl)phthalate
  • 4
    • 0036774846 scopus 로고    scopus 로고
    • Reproductive and neurobehavioral toxicity study of bis(2-ethylhexyl) phthalate (DEHP) administered to mice in the diet
    • Tanaka T. Reproductive and neurobehavioral toxicity study of bis(2-ethylhexyl) phthalate (DEHP) administered to mice in the diet. Food Chem Toxicol. 2002; 40: 1499-1506.
    • (2002) Food Chem Toxicol , vol.40 , pp. 1499-1506
    • Tanaka, T.1
  • 5
    • 84859359644 scopus 로고    scopus 로고
    • Environmental Protection Agency, Office of Ground Water and Drinking Water, Washington DC
    • Environmental Protection Agency. Technical Factsheet on: Di(2-ethyl)Phthalate (DEHP). Office of Ground Water and Drinking Water, Washington DC 1998.
    • (1998) Technical Factsheet on: Di(2-ethyl)Phthalate (DEHP)
  • 6
    • 0026638284 scopus 로고
    • Final report on the safety assessment of butyl benzyl phthalate
    • CIRC (Cosmetic Ingredient Review Committee)
    • CIRC (Cosmetic Ingredient Review Committee): Final report on the safety assessment of butyl benzyl phthalate. J Am Coll Toxicol. 1992; 11: 1-23.
    • (1992) J Am Coll Toxicol , vol.11 , pp. 1-23
  • 7
    • 0002353510 scopus 로고
    • The biochemical toxicology of di(2-ethylhexyl) and related phthalates: Testicular atrophy and hepatocarcinogenesis
    • Albro PW. The biochemical toxicology of di(2-ethylhexyl) and related phthalates: Testicular atrophy and hepatocarcinogenesis. Rev Biochem Toxicol. 1987; 8: 73-119.
    • (1987) Rev Biochem Toxicol , vol.8 , pp. 73-119
    • Albro, P.W.1
  • 10
    • 0016428097 scopus 로고
    • Identification and measurement of plasticizer in neonatal tissues after umbilical carters and blood products
    • Hillman LS, Goodwin LS, Sherman WR. Identification and measurement of plasticizer in neonatal tissues after umbilical carters and blood products. New England J Med. 1975; 292: 381-85.
    • (1975) New England J Med , vol.292 , pp. 381-385
    • Hillman, L.S.1    Goodwin, L.S.2    Sherman, W.R.3
  • 11
    • 0032958503 scopus 로고    scopus 로고
    • Changes in the concentration of erythrocyte membrane during storage of blood in di(2-ethylhexyl)phthalate (DEHP) plasticized poly vinyl chloride (PVC) blood storage bags
    • Manojkumar V, Deepadevi KV, Arun P, Nair KG, Lakshmi LR, Kurup PAS. Changes in the concentration of erythrocyte membrane during storage of blood in di(2-ethylhexyl)phthalate (DEHP) plasticized poly vinyl chloride (PVC) blood storage bags. Ind J Med Res. 1999; 109: 157-163.
    • (1999) Ind J Med Res , vol.109 , pp. 157-163
    • Manojkumar, V.1    Deepadevi, K.V.2    Arun, P.3    Nair, K.G.4    Lakshmi, L.R.5    Kurup, P.A.S.6
  • 12
    • 0022375644 scopus 로고
    • Effects of repeated intravenous infusions of the plasticizer di(2-ethylhexyl)phthalate in young male rats
    • Sjo{double acute}berg P, Lindquist NG, Montin G, Ploen L. Effects of repeated intravenous infusions of the plasticizer di(2-ethylhexyl)phthalate in young male rats. Arch Toxicol. 1985; 58: 78-83.
    • (1985) Arch Toxicol , vol.58 , pp. 78-83
    • Sjoberg, P.1    Lindquist, N.G.2    Montin, G.3    Ploen, L.4
  • 13
    • 0034521058 scopus 로고    scopus 로고
    • The plasticizer diethylhexyl phthalate induced malformations be decreasing fetal testosterone synthesis during sexual differentiation in the male rat
    • Parks LG, Ostby JS, Lambright CR, Abbott BD, Klinefelter GR, Barlow NJ, Gray LE Jr. The plasticizer diethylhexyl phthalate induced malformations be decreasing fetal testosterone synthesis during sexual differentiation in the male rat. Toxicol Sci. 2000; 58: 339-349.
    • (2000) Toxicol Sci , vol.58 , pp. 339-349
    • Parks, L.G.1    Ostby, J.S.2    Lambright, C.R.3    Abbott, B.D.4    Klinefelter, G.R.5    Barlow, N.J.6    Gray Jr., L.E.7
  • 14
    • 0035977842 scopus 로고    scopus 로고
    • Hormones and testis development and possible adverse effects of environmental chemicals
    • Sharpe RM. Hormones and testis development and possible adverse effects of environmental chemicals. Toxicol Lett. 2001; 120: 221-232.
    • (2001) Toxicol Lett , vol.120 , pp. 221-232
    • Sharpe, R.M.1
  • 15
    • 0035194978 scopus 로고    scopus 로고
    • Altered gene profiles and fetal rats testes after in utero exposure to di(n-buthyl)phthalate
    • Shultz VD, Philips S, Sar M, Foster PM, Gaido KW. Altered gene profiles and fetal rats testes after in utero exposure to di(n-buthyl)phthalate. Toxicol Sci. 2001; 64: 235-242.
    • (2001) Toxicol Sci , vol.64 , pp. 235-242
    • Shultz, V.D.1    Philips, S.2    Sar, M.3    Foster, P.M.4    Gaido, K.W.5
  • 16
    • 0036935523 scopus 로고    scopus 로고
    • Gene expression changes induced in mouse liver by di(2-ethylhexyl)phthalate
    • Wong JS, Gill SS. Gene expression changes induced in mouse liver by di(2-ethylhexyl)phthalate. Toxicol Appl Pharmacol. 2002; 185: 180-96.
    • (2002) Toxicol Appl Pharmacol , vol.185 , pp. 180-196
    • Wong, J.S.1    Gill, S.S.2
  • 20
    • 0041304143 scopus 로고    scopus 로고
    • ATSDR, Agency for Toxic Substances and Disease Registry, United States Public Health Service, Atlanta (GA)
    • ATSDR. Toxicological profile for di(2-ethylhexyl)phthalate (DEHP). Agency for Toxic Substances and Disease Registry, United States Public Health Service, Atlanta (GA) 2002.
    • (2002) Toxicological profile for di(2-ethylhexyl)phthalate (DEHP)
  • 21
    • 0034523473 scopus 로고    scopus 로고
    • Prenatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat
    • Gray LE Jr, Ostby J, Furr J, Price M, Veeramachaneni DN, Parks L. Prenatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat. Toxicol Sci. 2000; 58: 350-65.
    • (2000) Toxicol Sci , vol.58 , pp. 350-365
    • Gray Jr., L.E.1    Ostby, J.2    Furr, J.3    Price, M.4    Veeramachaneni, D.N.5    Parks, L.6
  • 22
    • 0035045792 scopus 로고    scopus 로고
    • Abnormalities of sexual development in male rats with in utero and lactational exposure to the antiandrogenic plasticizer di(2-ethylhexyl)phthalate
    • Moore RW, Rudy TA, Lin TM, Ko K, Peterson RE. Abnormalities of sexual development in male rats with in utero and lactational exposure to the antiandrogenic plasticizer di(2-ethylhexyl)phthalate. Environ Health Perspect. 2001; 109: 229-237.
    • (2001) Environ Health Perspect , vol.109 , pp. 229-237
    • Moore, R.W.1    Rudy, T.A.2    Lin, T.M.3    Ko, K.4    Peterson, R.E.5
  • 23
    • 0029083315 scopus 로고
    • The rodent dominant lethal assay: A proposed format for data presentation that alerts to pseudodominant lethal effects
    • Ashby J, Clapp MJL. The rodent dominant lethal assay: a proposed format for data presentation that alerts to pseudodominant lethal effects. Mutat Res. 1995; 330: 209-218
    • (1995) Mutat Res , vol.330 , pp. 209-218
    • Ashby, J.1    Clapp, M.J.L.2
  • 24
    • 0020130673 scopus 로고
    • IARC, Some Industrial Chemicals and Dyestuffs. Summary of Data Reported and Evaluation, IARC, Lyon 1982
    • IARC (1982) Monographs on the Evaluation of Carcinogenic Risk to Humans. Vol. 29: Some Industrial Chemicals and Dyestuffs. Summary of Data Reported and Evaluation, 269-293, IARC, Lyon 1982.
    • (1982) Monographs on the Evaluation of Carcinogenic Risk to Humans , vol.29 , pp. 269-293
  • 25
    • 0018825003 scopus 로고
    • Reduction in sperm count and increase in abnormal sperm in the mouse following X-radiation or injection of 22Na
    • Harrison A, Moore PC. Reduction in sperm count and increase in abnormal sperm in the mouse following X-radiation or injection of 22Na. Health Phys. 1980; 39: 219-224.
    • (1980) Health Phys , vol.39 , pp. 219-224
    • Harrison, A.1    Moore, P.C.2
  • 26
    • 0015980209 scopus 로고
    • Sperm count, egg-fertilization and dominant lethality after X-irradiation of mice
    • Searle AG, Beechey CV. Sperm count, egg-fertilization and dominant lethality after X-irradiation of mice. Mutat Res. 1974; 22: 69-74.
    • (1974) Mutat Res , vol.22 , pp. 69-74
    • Searle, A.G.1    Beechey, C.V.2
  • 27
    • 0021911302 scopus 로고
    • Reproductive effects of inhaled methyl chloride in the male Fisher 344 rat. II. Spermatogonial toxicity and sperm quality
    • Working PK, Bus JS, Hamm TE Jr. Reproductive effects of inhaled methyl chloride in the male Fisher 344 rat. II. Spermatogonial toxicity and sperm quality. Toxicol Appl Pharmacol. 1985; 77: 144-57.
    • (1985) Toxicol Appl Pharmacol , vol.77 , pp. 144-157
    • Working, P.K.1    Bus, J.S.2    Hamm Jr., T.E.3
  • 28
    • 0011796077 scopus 로고
    • Chemical induction of sperm abnormalities in mice
    • Wyrobek AJ, Bruce WR. Chemical induction of sperm abnormalities in mice. Proceed Nat Acad Sci USA. 1975; 72: 4425-4429.
    • (1975) Proceed Nat Acad Sci USA , vol.72 , pp. 4425-4429
    • Wyrobek, A.J.1    Bruce, W.R.2
  • 29
    • 0023919963 scopus 로고
    • A simple technique for quantization of low level of DNA damage in individual cells
    • Singh NP, Mc Coy M, Tice RR, Schneider EL. A simple technique for quantization of low level of DNA damage in individual cells. Exp Cell Res. 1988; 175: 184-191.
    • (1988) Exp Cell Res , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.2    Tice, R.R.3    Schneider, E.L.4
  • 30
    • 0028305534 scopus 로고
    • The effects of various antioxidants and other modifying agents on oxygen-radical-generated damage in human lymphocytes in Comet assay
    • Anderson D, Yu TW, Phillips BJ, Schmezer P. The effects of various antioxidants and other modifying agents on oxygen-radical-generated damage in human lymphocytes in Comet assay. Mutat Res. 1994; 307: 261-71.
    • (1994) Mutat Res , vol.307 , pp. 261-271
    • Anderson, D.1    Yu, T.W.2    Phillips, B.J.3    Schmezer, P.4
  • 32
    • 0017326305 scopus 로고
    • A proposed method for the simultaneous detection of germ cell mutations leading to foetal death (dominant lethality) and of malformations (male teratogenicity)
    • Knudsen I, Hansen EV, Meyer OA, Poulsen E. A proposed method for the simultaneous detection of germ cell mutations leading to foetal death (dominant lethality) and of malformations (male teratogenicity). Mutat Res. 1977; 48: 267-270.
    • (1977) Mutat Res , vol.48 , pp. 267-270
    • Knudsen, I.1    Hansen, E.V.2    Meyer, O.A.3    Poulsen, E.4
  • 33
    • 0027875970 scopus 로고
    • Male-mediated F1 effects in mice exposed to 1,3-butadiene
    • In: Sorsa M, Peltonen K, Vainio H, Hemminki K (Eds., IARC Scientific Publications No. 127, Lyon
    • Anderson D, Edwards AJ, Brinkworth, MH. Male-mediated F1 effects in mice exposed to 1,3-butadiene. In: Sorsa M, Peltonen K, Vainio H, Hemminki K (Eds.). Butadiene and Styrene: assessment of Health Hazards, 171-181. IARC Scientific Publications No. 127, Lyon 1993.
    • (1993) Butadiene and Styrene: Assessment of Health Hazards , pp. 171-181
    • Anderson, D.1    Edwards, A.J.2    Brinkworth, M.H.3
  • 34
    • 0021342762 scopus 로고
    • Induction of congenital malformations in the offspring of male mice treated with X-rays at pre-meiotic and postmeiotic stages
    • Kirk KM, Lyon MF. Induction of congenital malformations in the offspring of male mice treated with X-rays at pre-meiotic and postmeiotic stages. Mutat Res. 1984; 125: 75-85.
    • (1984) Mutat Res , vol.125 , pp. 75-85
    • Kirk, K.M.1    Lyon, M.F.2
  • 35
    • 0345435929 scopus 로고    scopus 로고
    • Effect of prenatal gamma irradiation during the late fetal period on the postnatal development on the mouse
    • Hossain M, Devi PU, Bisht KS. Effect of prenatal gamma irradiation during the late fetal period on the postnatal development on the mouse. Teratology. 1999; 59: 133-38.
    • (1999) Teratology , vol.59 , pp. 133-138
    • Hossain, M.1    Devi, P.U.2    Bisht, K.S.3
  • 39
    • 0030945599 scopus 로고    scopus 로고
    • Differential prenatal toxicity of branched phthalate esters in rats
    • Hellwig J, Freudenberger J, Jackh R. Differential prenatal toxicity of branched phthalate esters in rats. Food Chem Toxicol. 1997; 35: 501-12.
    • (1997) Food Chem Toxicol , vol.35 , pp. 501-512
    • Hellwig, J.1    Freudenberger, J.2    Jackh, R.3
  • 41
    • 67650718148 scopus 로고    scopus 로고
    • Transgenerational effects of di(2-ethylhexyl)phthalate in the male CRL:CD(SD) rat: Added value of assessing multiple offspring per litter
    • Gray LE, Barlow NJ, Howdeshell KL, Ostby JS, Furr JR, Gray CL. Transgenerational effects of di(2-ethylhexyl)phthalate in the male CRL:CD(SD) rat: added value of assessing multiple offspring per litter. Toxicol Sci. 2009; 110: 411-25.
    • (2009) Toxicol Sci , vol.110 , pp. 411-425
    • Gray, L.E.1    Barlow, N.J.2    Howdeshell, K.L.3    Ostby, J.S.4    Furr, J.R.5    Gray, C.L.6
  • 42
    • 0003498377 scopus 로고    scopus 로고
    • IARC, Some Industrial Chemicals Summary of Data Reported and Evaluation, 41-148, IARC, Lyon, 2000
    • IARC (2000) Monographs on the Evaluation of Carcinogenic Risk to Humans. Vol. 77: Some Industrial Chemicals Summary of Data Reported and Evaluation, 41-148, IARC, Lyon, 2000.
    • (2000) Monographs on the Evaluation of Carcinogenic Risk to Humans , vol.77
  • 44
    • 0021916047 scopus 로고
    • Assessment of the teratogenicity of di(2-ethylhexyl) phthalate and mono(2-ethylhexyl)phthalate in mice
    • Shiota K, Mima S. Assessment of the teratogenicity of di(2-ethylhexyl) phthalate and mono(2-ethylhexyl)phthalate in mice. Arch Toxicol. 1985; 56: 263-266.
    • (1985) Arch Toxicol , vol.56 , pp. 263-266
    • Shiota, K.1    Mima, S.2
  • 45
    • 0023125575 scopus 로고
    • Hepatic peroxisome proliferation and hypolipidemic effects of di(2-ethylhexyl)phthalate in neonatal and adult rats
    • Dostal LA, Jenkins WL, Schwetz BA. Hepatic peroxisome proliferation and hypolipidemic effects of di(2-ethylhexyl)phthalate in neonatal and adult rats. Toxicol Appl Pharmacol. 1987; 87: 81-90.
    • (1987) Toxicol Appl Pharmacol , vol.87 , pp. 81-90
    • Dostal, L.A.1    Jenkins, W.L.2    Schwetz, B.A.3
  • 46
    • 75749149769 scopus 로고    scopus 로고
    • Comparative toxicological evaluation of phthalate diesters and metabolites in Sprague-Dawley male rats for risk assessment
    • Kwack SJ, Kim KB, Kim HS, Lee BM. Comparative toxicological evaluation of phthalate diesters and metabolites in Sprague-Dawley male rats for risk assessment. J Toxicol Environ Health A. 2009; 72: 1446-54.
    • (2009) J Toxicol Environ Health A , vol.72 , pp. 1446-1454
    • Kwack, S.J.1    Kim, K.B.2    Kim, H.S.3    Lee, B.M.4
  • 47
    • 0022973652 scopus 로고
    • Effect of di(2-ethylhexyl)phthalate (DEHP) on spermatogenesis in adult rats
    • Parmar D, Srivastava SP, Seth PK. Effect of di(2-ethylhexyl)phthalate (DEHP) on spermatogenesis in adult rats. Toxicology. 1986; 42: 47-55.
    • (1986) Toxicology , vol.42 , pp. 47-55
    • Parmar, D.1    Srivastava, S.P.2    Seth, P.K.3
  • 48
    • 0026558755 scopus 로고
    • Effect of di(2-ethylhexyl)phthalate administration on rat sperm count and on sperm metabolic enzymes
    • Siddiqui A, Srivastava SP. Effect of di(2-ethylhexyl)phthalate administration on rat sperm count and on sperm metabolic enzymes. Bull Environ Contam Toxicol. 1992; 48: 115-19.
    • (1992) Bull Environ Contam Toxicol , vol.48 , pp. 115-119
    • Siddiqui, A.1    Srivastava, S.P.2
  • 49
    • 0022560406 scopus 로고
    • Effects of di(2-ethylhexyl) phthalate on the gonadal pathophysiology, sperm morphology, and reproductive performance of male rats
    • Agarwal DK, Eustis S, Lamb JC, Reel JR, Kluwe WM. Effects of di(2-ethylhexyl) phthalate on the gonadal pathophysiology, sperm morphology, and reproductive performance of male rats. Environ Health Perspect. 1986; 65: 343-50.
    • (1986) Environ Health Perspect , vol.65 , pp. 343-350
    • Agarwal, D.K.1    Eustis, S.2    Lamb, J.C.3    Reel, J.R.4    Kluwe, W.M.5
  • 50
    • 84859347228 scopus 로고    scopus 로고
    • Male-mediated F1 effects in mice exposed to di(2-ethylhexyl)phthalate (DEHP)
    • In: Anderson D, Brinkworth MH (Eds., RSC Publishing
    • Dobrzyńska MM, Czajka U, Tyrkiel EJ. Male-mediated F1 effects in mice exposed to di(2-ethylhexyl)phthalate (DEHP). In: Anderson D, Brinkworth MH (Eds.). Male-mediated developmental toxicity. RSC Publishing 2007.
    • (2007) Male-mediated developmental toxicity
    • Dobrzyńska, M.M.1    Czajka, U.2    Tyrkiel, E.J.3
  • 51
    • 0019995497 scopus 로고
    • Differences in the movement of morphologically normal and abnormal human seminal spermatozoa
    • Katz DF, Diel L, Overstreet JW. Differences in the movement of morphologically normal and abnormal human seminal spermatozoa. Biol Reprod. 1982; 26: 566-70.
    • (1982) Biol Reprod , vol.26 , pp. 566-570
    • Katz, D.F.1    Diel, L.2    Overstreet, J.W.3
  • 52
    • 0037930856 scopus 로고    scopus 로고
    • Study designs for the assessment of male-mediated developmental toxicity
    • In: Robaire B, Hales BF (Eds.,. Kluwer Academic/Plenum Publishers, New York
    • Hales BF, Cyr DG. Study designs for the assessment of male-mediated developmental toxicity. In: Robaire B, Hales BF (Eds.). Advances in male mediated developmental toxicology. 271-77. Kluwer Academic/Plenum Publishers, New York 2003.
    • (2003) Advances in male mediated developmental toxicology , pp. 271-277
    • Hales, B.F.1    Cyr, D.G.2
  • 53
    • 0002621091 scopus 로고
    • The dominant lethal asssay in the mouse
    • In: Kilbey B, Legator M, Nicholl W, Ramel C (Eds., Elsevier, Amsterdam
    • Bateman AJ. The dominant lethal asssay in the mouse. In: Kilbey B, Legator M, Nicholl W, Ramel C (Eds.). Handbook of Mutagenicity test procedures, 325-35. Elsevier, Amsterdam 1977.
    • (1977) Handbook of Mutagenicity test procedures , pp. 325-335
    • Bateman, A.J.1
  • 54
    • 0023751785 scopus 로고
    • Testicular toxicity and reduced Sertoli cell numbers in neonatal rats by di(2-ethylhexyl)phthalate and the recovery of fertility as adults
    • Dostal LA, Chapin RE, Stefanski SA, Harris MW, Schwetz BA. Testicular toxicity and reduced Sertoli cell numbers in neonatal rats by di(2-ethylhexyl)phthalate and the recovery of fertility as adults. Toxicol Appl Pharmacol. 1988; 95: 104-21.
    • (1988) Toxicol Appl Pharmacol , vol.95 , pp. 104-121
    • Dostal, L.A.1    Chapin, R.E.2    Stefanski, S.A.3    Harris, M.W.4    Schwetz, B.A.5
  • 57
    • 0037765476 scopus 로고    scopus 로고
    • Decreased anogenital distance and increased incidence of undescended testes in fetuses of rats given monobenzyl phthalate, a major metabolite of butyl benzyl phthalate
    • Ema M, Miyawaki NE, Hirose A, Kamata E. Decreased anogenital distance and increased incidence of undescended testes in fetuses of rats given monobenzyl phthalate, a major metabolite of butyl benzyl phthalate. Reprod Toxicol. 2003; 17: 407-12.
    • (2003) Reprod Toxicol , vol.17 , pp. 407-412
    • Ema, M.1    Miyawaki, N.E.2    Hirose, A.3    Kamata, E.4
  • 58
    • 69049111032 scopus 로고    scopus 로고
    • Pubertal administration of DEHP delays puberty, suppresses testosterone production, and inhibits reproductive tract development in male Sprague-Dawley and Long-Evants rats
    • Noriega NC, Howdeshell KL, Furr J, Lambright CR, Wilson VS, Gray LE Jr. Pubertal administration of DEHP delays puberty, suppresses testosterone production, and inhibits reproductive tract development in male Sprague-Dawley and Long-Evants rats. Toxicol Sci. 2009; 111: 163-78.
    • (2009) Toxicol Sci , vol.111 , pp. 163-178
    • Noriega, N.C.1    Howdeshell, K.L.2    Furr, J.3    Lambright, C.R.4    Wilson, V.S.5    Gray Jr., L.E.6
  • 59
    • 68049129723 scopus 로고    scopus 로고
    • Effects of di(2-ethylhexyl)phthalate on the testis and testicular gubernaculums of fetal KM mice (Abstr)
    • Song XF, Deng YJ, Zhang DY, Liu X, Wu SD, Wei GH. Effects of di(2-ethylhexyl)phthalate on the testis and testicular gubernaculums of fetal KM mice (Abstr). Zhonghua Nan Ke Xue. 2009; 15: 195-99.
    • (2009) Zhonghua Nan Ke Xue , vol.15 , pp. 195-199
    • Song, X.F.1    Deng, Y.J.2    Zhang, D.Y.3    Liu, X.4    Wu, S.D.5    Wei, G.H.6
  • 60
    • 33749659139 scopus 로고    scopus 로고
    • A dose response study following in utero and lactational exposure to di(2-ethylhexyl)phthalate (DEHP): Reproductive effects on adult male offspring rats
    • Andrade AJ, Grande SW, Talsness CE, Gericke C, Grote K, Golembiewski A, Sterner-Kock A, Chahoud I. A dose response study following in utero and lactational exposure to di(2-ethylhexyl)phthalate (DEHP): reproductive effects on adult male offspring rats. Toxicology. 2006; 228: 85-97.
    • (2006) Toxicology , vol.228 , pp. 85-97
    • Andrade, A.J.1    Grande, S.W.2    Talsness, C.E.3    Gericke, C.4    Grote, K.5    Golembiewski, A.6    Sterner-Kock, A.7    Chahoud, I.8
  • 62
    • 70349679190 scopus 로고    scopus 로고
    • Differential effects of flutamide and di(2-ethylhexyl) phthalate on male reproductive organs in rat model
    • Vo TTB, Jung EM, Dang VH, Jung R, Baek J, Choi KC Jeung EB. Differential effects of flutamide and di(2-ethylhexyl) phthalate on male reproductive organs in rat model. J Reprod Develop. 2009; 55: 400-11.
    • (2009) J Reprod Develop , vol.55 , pp. 400-411
    • Vo, T.T.B.1    Jung, E.M.2    Dang, V.H.3    Jung, R.4    Baek, J.5    Choi, K.C.6    Jeung, E.B.7
  • 63
    • 0026657024 scopus 로고
    • Evidence for decreasing quality of semen during the past 50 years
    • Carlsen E, Giwercman A, Keiding N, Skakkebaek NE. Evidence for decreasing quality of semen during the past 50 years. BMJ. 1992; 305: 609-612.
    • (1992) BMJ , vol.305 , pp. 609-612
    • Carlsen, E.1    Giwercman, A.2    Keiding, N.3    Skakkebaek, N.E.4
  • 64
    • 46349089543 scopus 로고    scopus 로고
    • The fertilization of donor semen between 1982 and 2004 in the industrial area of Upper Silesia (Poland)
    • Horak S, Kamińska J, Olejek A. The fertilization of donor semen between 1982 and 2004 in the industrial area of Upper Silesia (Poland). Ann Agric Environ Med. 2008; 15: 113-118.
    • (2008) Ann Agric Environ Med , vol.15 , pp. 113-118
    • Horak, S.1    Kamińska, J.2    Olejek, A.3
  • 65
    • 0033724655 scopus 로고    scopus 로고
    • The question of declining sperm density revisited: An analysis of 101 studies published 1934-1996
    • Swan SH, Elkin EP, Fenster L. The question of declining sperm density revisited: An analysis of 101 studies published 1934-1996. Environ Health Perspect. 2000; 108: 961-966.
    • (2000) Environ Health Perspect , vol.108 , pp. 961-966
    • Swan, S.H.1    Elkin, E.P.2    Fenster, L.3
  • 66
    • 0019280981 scopus 로고
    • Testicular atrophy produced by phthalate esters
    • Gray TJ, Butterworth KR. Testicular atrophy produced by phthalate esters. Arch Toxicol. 1980; Suppl 4: 432-455.
    • (1980) Arch Toxicol , Issue.SUPPL. 4 , pp. 432-455
    • Gray, T.J.1    Butterworth, K.R.2
  • 67
    • 0021339760 scopus 로고
    • Effect of some phthalates esters and other testicular toxins on primary cultures of testicular cells
    • Gray TJ, Beamand JA. Effect of some phthalates esters and other testicular toxins on primary cultures of testicular cells. Food Chem Toxicol. 1984; 22: 123-31.
    • (1984) Food Chem Toxicol , vol.22 , pp. 123-131
    • Gray, T.J.1    Beamand, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.