ATP-triggered conformational changes delineate substrate-binding and -folding mechanics of the GroEL chaperonin

Cell

Volumn 149, Issue 1, 2012, Pages 113-123

  Clare, Daniel K ^a   Vasishtan, Daven ^a   Stagg, Scott ^b,d   Quispe, Joel ^b   Farr, George W ^c,e   Topf, Maya ^a   Horwich, Arthur L ^b,c   Saibil, Helen R ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d FLORIDA STATE UNIVERSITY   (United States)

^e Aeromics LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CHAPERONIN; POLYPEPTIDE; PROTEIN GROES; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CRYOELECTRON MICROSCOPY; FORCE; HYDROPHOBICITY; MECHANICS; MOLECULAR DOCKING; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN DOMAIN; PROTEIN FOLDING;

EID: 84859211500     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2012.02.047     Document Type: Article

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