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Volumn 130, Issue 11, 2012, Pages 2557-2567

3-Deazaneplanocin A is a promising therapeutic agent for the eradication of tumor-initiating hepatocellular carcinoma cells

Author keywords

cancer stem cell; DZNep; EZH2; hepatocellular carcinoma; tumor initiating cell

Indexed keywords

3 DEAZANEPLANOCIN A; EPITHELIAL CELL ADHESION MOLECULE; FLUOROURACIL; TRANSCRIPTION FACTOR EZH2;

EID: 84859157028     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.26264     Document Type: Article
Times cited : (98)

References (35)
  • 1
    • 0002740313 scopus 로고
    • A quantitative assay for the number of murine lymphoma cells capable of proliferation in vivo
    • Bruce WR, Van Der Gaag H,. A quantitative assay for the number of murine lymphoma cells capable of proliferation in vivo. Nature 1963; 199: 79-80.
    • (1963) Nature , vol.199 , pp. 79-80
    • Bruce, W.R.1    Van Der Gaag, H.2
  • 3
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • Bonnet D, Dick JE,. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997; 3: 730-7.
    • (1997) Nat Med , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 5
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
    • Visvader JE, Lindeman GJ,. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 2008; 8: 755-68.
    • (2008) Nat Rev Cancer , vol.8 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 12
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • Dean M, Fojo T, Bates S,. Tumour stem cells and drug resistance. Nat Rev Cancer 2005; 5: 275-84.
    • (2005) Nat Rev Cancer , vol.5 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 15
    • 0037673984 scopus 로고    scopus 로고
    • Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
    • Lessard J, Sauvageau G,. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 2003; 423: 255-60.
    • (2003) Nature , vol.423 , pp. 255-260
    • Lessard, J.1    Sauvageau, G.2
  • 17
    • 70349469565 scopus 로고    scopus 로고
    • Chromatin dynamics mechanisms of polycomb gene silencing: Knowns and unknowns
    • Simon JA, Kingston RE,. Chromatin dynamics mechanisms of polycomb gene silencing: knowns and unknowns. Nat Rev Mol Cell Biol 2009; 10: 697-708.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 697-708
    • Simon, J.A.1    Kingston, R.E.2
  • 18
    • 41749108163 scopus 로고    scopus 로고
    • Stem cell regulation by polycomb repressors: Postponing commitment
    • Pietersen AM, van Lohuizen M,. Stem cell regulation by polycomb repressors: postponing commitment. Curr Opin Cell Biol 2008; 20: 201-7.
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 201-207
    • Pietersen, A.M.1    Van Lohuizen, M.2
  • 19
    • 77952430646 scopus 로고    scopus 로고
    • The polycomb group gene product Ezh2 regulates proliferation and differentiation of murine hepatic stem/progenitor cells
    • Aoki R, Chiba T, Miyagi S, Negishi M, Konuma T, Taniguchi H, Ogawa M, Yokosuka O, Iwama A,. The polycomb group gene product Ezh2 regulates proliferation and differentiation of murine hepatic stem/progenitor cells. J Hepatol 2010; 52: 854-63.
    • (2010) J Hepatol , vol.52 , pp. 854-863
    • Aoki, R.1    Chiba, T.2    Miyagi, S.3    Negishi, M.4    Konuma, T.5    Taniguchi, H.6    Ogawa, M.7    Yokosuka, O.8    Iwama, A.9
  • 20
    • 67649371461 scopus 로고    scopus 로고
    • DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation
    • Miranda TB, Cortez CC, Yoo CB, Liang G, Abe M, Kelly TK, Marquez VE, Jones PA,. DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation. Mol Cancer Ther 2009; 8: 1579-88.
    • (2009) Mol Cancer Ther , vol.8 , pp. 1579-1588
    • Miranda, T.B.1    Cortez, C.C.2    Yoo, C.B.3    Liang, G.4    Abe, M.5    Kelly, T.K.6    Marquez, V.E.7    Jones, P.A.8
  • 21
    • 34247625135 scopus 로고    scopus 로고
    • Pharmacologic disruption of polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells
    • Tan J, Yang X, Zhuang L, Jiang X, Chen W, Lee PL, Karuturi RK, Tan PB, Liu ET, Yu Q,. Pharmacologic disruption of polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells. Genes Dev 2007; 21: 1050-63.
    • (2007) Genes Dev , vol.21 , pp. 1050-1063
    • Tan, J.1    Yang, X.2    Zhuang, L.3    Jiang, X.4    Chen, W.5    Lee, P.L.6    Karuturi, R.K.7    Tan, P.B.8    Liu, E.T.9    Yu, Q.10
  • 23
    • 75749093015 scopus 로고    scopus 로고
    • Deregulation of H3K27 methylation in cancer
    • Martinez-Garcia E, Licht JD,. Deregulation of H3K27 methylation in cancer. Nat Genet 2010; 42: 100-1.
    • (2010) Nat Genet , vol.42 , pp. 100-101
    • Martinez-Garcia, E.1    Licht, J.D.2
  • 26
    • 48749104292 scopus 로고    scopus 로고
    • The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma
    • Sasaki M, Ikeda H, Itatsu K, Yamaguchi J, Sawada S, Minato H, Ohta T, Nakanuma Y,. The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma. Lab Invest 2008; 88: 873-82.
    • (2008) Lab Invest , vol.88 , pp. 873-882
    • Sasaki, M.1    Ikeda, H.2    Itatsu, K.3    Yamaguchi, J.4    Sawada, S.5    Minato, H.6    Ohta, T.7    Nakanuma, Y.8
  • 28
    • 56149088742 scopus 로고    scopus 로고
    • Differentiation therapy of hepatocellular carcinoma in mice with recombinant adenovirus carrying hepatocyte nuclear factor-4alpha gene
    • Yin C, Lin Y, Zhang X, Chen YX, Zeng X, Yue HY, Hou JL, Deng X, Zhang JP, Han ZG, Xie WF,. Differentiation therapy of hepatocellular carcinoma in mice with recombinant adenovirus carrying hepatocyte nuclear factor-4alpha gene. Hepatology 2008; 48: 1528-39.
    • (2008) Hepatology , vol.48 , pp. 1528-1539
    • Yin, C.1    Lin, Y.2    Zhang, X.3    Chen, Y.X.4    Zeng, X.5    Yue, H.Y.6    Hou, J.L.7    Deng, X.8    Zhang, J.P.9    Han, Z.G.10    Xie, W.F.11
  • 29
    • 71749118560 scopus 로고    scopus 로고
    • Cancer stem cells in hepatocellular carcinoma: Recent progress and perspective
    • Chiba T, Kamiya A, Yokosuka O, Iwama A,. Cancer stem cells in hepatocellular carcinoma: recent progress and perspective. Cancer Lett 2009; 286: 145-53.
    • (2009) Cancer Lett , vol.286 , pp. 145-153
    • Chiba, T.1    Kamiya, A.2    Yokosuka, O.3    Iwama, A.4
  • 30
    • 2942691389 scopus 로고    scopus 로고
    • Stem cell origin of cancer and differentiation therapy
    • Sell S,. Stem cell origin of cancer and differentiation therapy. Crit Rev Oncol Hematol 2004; 51: 1-28.
    • (2004) Crit Rev Oncol Hematol , vol.51 , pp. 1-28
    • Sell, S.1
  • 32
    • 31344466008 scopus 로고    scopus 로고
    • DNA methylation and gene silencing in cancer
    • Baylin SB,. DNA methylation and gene silencing in cancer. Nat Clin Pract Oncol 2005; 2 (Suppl 1): S4-S11.
    • (2005) Nat Clin Pract Oncol , vol.2 , Issue.SUPPL. 1
    • Baylin, S.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.