Allergen-induced IgE-dependent gut inflammation in a human PBMC-engrafted murine model of allergy

Journal of Allergy and Clinical Immunology

Volumn 129, Issue 4, 2012, Pages 1126-1135

  Weigmann, Benno ^a   Schughart, Nadja ^b   Wiebe, Christian ^b   Sudowe, Stephan ^b   Lehr, Hans A ^c   Jonuleit, Helmut ^b   Vogel, Lothar ^d   Becker, Christoph ^a   Neurath, Markus F ^a   Grabbe, Stephan ^b   Saloga, Joachim ^b   Bellinghausen, Iris ^b  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c UNIVERSITY INSTITUTE OF PATHOLOGY   (Switzerland)

^d PAUL EHRLICH INSTITUT   (Germany)

Author keywords

allergen; basophils; colon; histamine; Humanized mice; IgE; inflammation; platelet activating factor

Indexed keywords

4 ETHYNYL 3 [3 FLUORO 4 [(2 METHYL 1H IMIDAZO[4,5 C]PYRIDIN 1 YL)METHYL]BENZOYL] N,N DIMETHYL 1H INDOLE 1 CARBOXAMIDE; ALLERGEN; CIMETIDINE; GAMMA INTERFERON; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; MEPYRAMINE; OMALIZUMAB; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST;

ALLERGY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GRASS POLLEN; HAZELNUT; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOLOGY; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SPLEEN; VIDEOENDOSCOPY;

ADMINISTRATION, ORAL; ADMINISTRATION, RECTAL; ALLERGENS; ANIMALS; ANTIBODY SPECIFICITY; CD4-POSITIVE T-LYMPHOCYTES; CYTOKINES; DISEASE MODELS, ANIMAL; GASTRITIS; HISTAMINE ANTAGONISTS; HUMANS; HYPERSENSITIVITY; IMMUNOGLOBULIN E; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; MICE; MICE, KNOCKOUT; MICE, SCID; PLATELET MEMBRANE GLYCOPROTEINS; POLLEN; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, IGE; SPLEEN;

EID: 84859156295     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2011.11.036     Document Type: Article

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