High-level expression of bioactive recombinant human lysozyme in the milk of transgenic mice using a modified human lactoferrin BAC

Transgenic Research

Volumn 21, Issue 2, 2012, Pages 407-414

  Liu, Shen ^a   Li, Xiangqing ^a   Lu, Dan ^a   Shang, Shengzhe ^a   Wang, Meili ^b   Zheng, Min ^b   Zhang, Ran ^a   Tang, Bo ^a   Li, Qiuyan ^a   Dai, Yunping ^a   Li, Ning ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b GenProtein Biotech Ltd   (China)

Author keywords

Human lactoferrin bacterial artificial chromosome (hLF BAC); Milk; Recombinant human lysozyme (rhLZ); Recombineering; Transgenic mice

Indexed keywords

ANTIINFECTIVE AGENT; LACTOFERRIN; LYSOZYME; RECOMBINANT PROTEIN;

ANIMAL; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; BIOSYNTHESIS; DRUG EFFECT; FEMALE; GENE EXPRESSION REGULATION; GENE VECTOR; GENETIC ENGINEERING; GENETIC TRANSCRIPTION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; HUMAN GENOME; MALE; METABOLISM; METHODOLOGY; MICROBIOLOGICAL EXAMINATION; MICROCOCCUS; MILK; MOUSE; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANIMALS; ANTI-INFECTIVE AGENTS; BLOTTING, WESTERN; CHROMOSOMES, ARTIFICIAL, BACTERIAL; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENETIC ENGINEERING; GENETIC VECTORS; GENOME, HUMAN; HUMANS; LACTOFERRIN; MALE; MICE; MICE, TRANSGENIC; MICROBIAL SENSITIVITY TESTS; MICROCOCCUS; MILK; MURAMIDASE; RECOMBINANT PROTEINS; TRANSCRIPTION, GENETIC;

BACTERIA (MICROORGANISMS); MUS MUSCULUS;

EID: 84859104411     PISSN: 09628819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11248-011-9536-4     Document Type: Article

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