Repeated exposure to sublethal doses of the organophosphorus compound VX activates bdnf expression in mouse brain

Toxicological Sciences

Volumn 126, Issue 2, 2012, Pages 497-505

  Pizarro, Jose M ^a,b   Chang, Wenling E ^b,c   Bah, Mariama J ^b   Wright, Linnzi K M ^a   Saviolakis, George A ^b   Alagappan, Arun ^b   Robison, Christopher L ^a,b   Shah, Jinesh D ^b   Meyerhoff, James L ^b   Cerasoli, Douglas M ^a   Midboe, Eric G ^a   Lumley, Lucille A ^a,b  

^a US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

^b WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^c MITRE CORPORATION   (United States)

Author keywords

BDNF; Chemical warfare nerve agents; Mice; Neurotrophins; Organophosphorus compounds; VX

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA; O ETHYL S [2 (DIISOPROPYLAMINO)ETHYL]METHYLPHOSPHONATE; ORGANOPHOSPHORUS COMPOUND; UNCLASSIFIED DRUG;

AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN DAMAGE; BRAIN REGION; CELL DAMAGE; CELL SURVIVAL; CONTROLLED STUDY; DENTATE GYRUS; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; HIPPOCAMPUS; HYPOTHALAMUS; LETHAL DOSE; MALE; MOUSE; NERVE CELL PLASTICITY; NEUROTOXICITY; NONHUMAN; PROTEIN EXPRESSION; PYRIFORM CORTEX; THALAMUS;

MUS;

EID: 84859089582     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr353     Document Type: Article

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