-
1
-
-
42549088683
-
Thyroid carcinoma: Molecular pathways and therapeutic targets
-
Nikiforov YE. (2008) Thyroid carcinoma: molecular pathways and therapeutic targets. Mod. Pathol. 21(Suppl 2):S37-43.
-
(2008)
Mod. Pathol.
, vol.21
, Issue.SUPPL. 2
-
-
Nikiforov, Y.E.1
-
2
-
-
0242320299
-
Controversies in papillary microcarcinoma of the thyroid
-
Piersanti M, Ezzat S, Asa SL. (2003) Controversies in papillary microcarcinoma of the thyroid. Endocr. Pathol. 14:183-91.
-
(2003)
Endocr. Pathol.
, vol.14
, pp. 183-191
-
-
Piersanti, M.1
Ezzat, S.2
Asa, S.L.3
-
3
-
-
0030726290
-
Pathological tumor-node-metastasis (pTNM) staging for papillary and follicular thyroid carcinomas: A retrospective analysis of 700 patients
-
Loh KC, Greenspan FS, Gee L, Miller TR, Yeo PP. (1997) Pathological tumor-node-metastasis (pTNM) staging for papillary and follicular thyroid carcinomas: a retrospective analysis of 700 patients. J. Clin. Endocrinol. Metab. 82:3553-62.
-
(1997)
J. Clin. Endocrinol. Metab.
, vol.82
, pp. 3553-3562
-
-
Loh, K.C.1
Greenspan, F.S.2
Gee, L.3
Miller, T.R.4
Yeo, P.P.5
-
5
-
-
17244376576
-
Prognostic factors in papillary thyroid cancer: An evaluation of 601 consecutive patients
-
Siironen P, et al. (2005) Prognostic factors in papillary thyroid cancer: an evaluation of 601 consecutive patients. Tumour Biol. 26:57-64.
-
(2005)
Tumour Biol.
, vol.26
, pp. 57-64
-
-
Siironen, P.1
-
6
-
-
0023674310
-
Characterization of the TPR-MET oncogene p65 and the MET protooncogene p140 protein-tyrosine kinases
-
Gonzatti-Haces M, et al. (1988) Characterization of the TPR-MET oncogene p65 and the MET protooncogene p140 protein-tyrosine kinases. Proc. Natl. Acad. Sci. U. S. A. 85:21-5.
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 21-25
-
-
Gonzatti-Haces, M.1
-
7
-
-
0028500509
-
Identification of functional domains in the hepatocyte growth factor and its receptor by molecular engineering
-
Bardelli A, Ponzetto C, Comoglio PM. (1994) Identification of functional domains in the hepatocyte growth factor and its receptor by molecular engineering. J. Biotechnol. 37:109-22.
-
(1994)
J. Biotechnol.
, vol.37
, pp. 109-122
-
-
Bardelli, A.1
Ponzetto, C.2
Comoglio, P.M.3
-
8
-
-
38449103771
-
The biological role of HGF-MET axis in tumor growth and development of metastasis
-
Lesko E, Majka M. (2008) The biological role of HGF-MET axis in tumor growth and development of metastasis. Front. Biosci. 13:1271-80.
-
(2008)
Front. Biosci.
, vol.13
, pp. 1271-1280
-
-
Lesko, E.1
Majka, M.2
-
9
-
-
34250016782
-
Hepatocyte growth factor in invasive growth of carcinomas
-
Desiderio MA. (2007) Hepatocyte growth factor in invasive growth of carcinomas. Cell. Mol. Life Sci. 64:1341-54.
-
(2007)
Cell. Mol. Life Sci.
, vol.64
, pp. 1341-1354
-
-
Desiderio, M.A.1
-
10
-
-
39449117410
-
The shadow of death on the MET tyrosine kinase receptor
-
Tulasne D, Foveau B. (2008) The shadow of death on the MET tyrosine kinase receptor. Cell. Death Differ. 15:427-434.
-
(2008)
Cell. Death Differ.
, vol.15
, pp. 427-434
-
-
Tulasne, D.1
Foveau, B.2
-
11
-
-
4344644698
-
Activation of the hepatocyte growth factor (HGF)-Met system in papillary thyroid cancer: Biological effects of HGF in thyroid cancer cells depend on Met expression levels
-
Mineo R, et al. (2004) Activation of the hepatocyte growth factor (HGF)-Met system in papillary thyroid cancer: biological effects of HGF in thyroid cancer cells depend on Met expression levels. Endocrinology. 145:4355-65.
-
(2004)
Endocrinology.
, vol.145
, pp. 4355-4365
-
-
Mineo, R.1
-
12
-
-
0035031095
-
Met protein and hepatocyte growth factor (HGF) in papillary carcinoma of the thyroid: Evidence for a pathogenetic role in tumourigenesis
-
Ruco LP, Stoppacciaro A, Ballarini F, Prat M, Scarpino S. (2001) Met protein and hepatocyte growth factor (HGF) in papillary carcinoma of the thyroid: evidence for a pathogenetic role in tumourigenesis. J. Pathol. 194:4-8.
-
(2001)
J. Pathol.
, vol.194
, pp. 4-8
-
-
Ruco, L.P.1
Stoppacciaro, A.2
Ballarini, F.3
Prat, M.4
Scarpino, S.5
-
13
-
-
0037242227
-
Hepatocyte growth factor receptor, matrix metalloproteinase-11, tissue inhibitor of metalloproteinase-1, and fibronectin are up-regulated in papillary thyroid carcinoma: A cDNA and tissue microarray study
-
Wasenius VM, Hemmer S, Kettunen E, Knuutila S, Franssila K, Joensuu H. (2003) Hepatocyte growth factor receptor, matrix metalloproteinase-11, tissue inhibitor of metalloproteinase-1, and fibronectin are up-regulated in papillary thyroid carcinoma: a cDNA and tissue microarray study. Clin. Cancer Res. 9:68-75.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 68-75
-
-
Wasenius, V.M.1
Hemmer, S.2
Kettunen, E.3
Knuutila, S.4
Franssila, K.5
Joensuu, H.6
-
14
-
-
35349011718
-
Genome-wide expression analysis of Middle Eastern papillary thyroid cancer reveals c-MET as a novel target for cancer therapy
-
Siraj AK, et al. (2007) Genome-wide expression analysis of Middle Eastern papillary thyroid cancer reveals c-MET as a novel target for cancer therapy. J. Pathol. 213:190-9.
-
(2007)
J. Pathol.
, vol.213
, pp. 190-199
-
-
Siraj, A.K.1
-
17
-
-
33749316735
-
Prevalence of fragile histidine triad expression in tumors from Saudi Arabia: A tissue microarray analysis
-
Bavi P, et al. (2006) Prevalence of fragile histidine triad expression in tumors from Saudi Arabia: a tissue microarray analysis. Cancer Epidemiol. Biomarkers Prev. 15:1708-18.
-
(2006)
Cancer Epidemiol. Biomarkers Prev.
, vol.15
, pp. 1708-1718
-
-
Bavi, P.1
-
18
-
-
53749104732
-
Fatty acid synthase and AKT pathway signaling in a subset of papillary thyroid cancers
-
Uddin S, et al. (2008) Fatty acid synthase and AKT pathway signaling in a subset of papillary thyroid cancers. J. Clin. Endocrinol. Metab. 93:4088-97.
-
(2008)
J. Clin. Endocrinol. Metab.
, vol.93
, pp. 4088-4097
-
-
Uddin, S.1
-
19
-
-
33845501828
-
Role of phosphatidylinositol 33-kinase/AKT pathway in diffuse large B-cell lymphoma survival
-
Uddin S, et al. (2006) Role of phosphatidylinositol 33-kinase/AKT pathway in diffuse large B-cell lymphoma survival. Blood. 108:4178-86.
-
(2006)
Blood.
, vol.108
, pp. 4178-4186
-
-
Uddin, S.1
-
20
-
-
44449124376
-
Clinicopathological analysis of colorectal cancers with PIK3CA mutations in Middle Eastern population
-
Abubaker J, et al. (2008) Clinicopathological analysis of colorectal cancers with PIK3CA mutations in Middle Eastern population. Oncogene. 27:3539-45.
-
(2008)
Oncogene.
, vol.27
, pp. 3539-3545
-
-
Abubaker, J.1
-
21
-
-
19644387196
-
The Akt inhibitor KP372-1 suppresses Akt activity and cell proliferation and induces apoptosis in thyroid cancer cells
-
Mandal M, et al. (2005) The Akt inhibitor KP372-1 suppresses Akt activity and cell proliferation and induces apoptosis in thyroid cancer cells. Br. J. Cancer. 92:1899-905.
-
(2005)
Br. J. Cancer.
, vol.92
, pp. 1899-1905
-
-
Mandal, M.1
-
22
-
-
33344461738
-
Curcumin induces apoptosis via inhibition of PI3v-kinase/AKT pathway in acute T cell leukemias
-
Hussain AR, et al. (2006) Curcumin induces apoptosis via inhibition of PI3v-kinase/AKT pathway in acute T cell leukemias. Apoptosis. 11:245-54.
-
(2006)
Apoptosis.
, vol.11
, pp. 245-254
-
-
Hussain, A.R.1
-
23
-
-
3042801429
-
Inhibition of phosphatidylinositol 33-kinase induces preferentially killing of PTEN-null T leukemias through AKT pathway
-
Uddin S, Hussain A, Al-Hussein K, Platanias LC, Bhatia KG. (2004) Inhibition of phosphatidylinositol 33-kinase induces preferentially killing of PTEN-null T leukemias through AKT pathway. Biochem. Biophys. Res. Commun. 320:932-8.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.320
, pp. 932-938
-
-
Uddin, S.1
Hussain, A.2
Al-Hussein, K.3
Platanias, L.C.4
Bhatia, K.G.5
-
24
-
-
34248582774
-
Sanguinarine-dependent induction of apoptosis in primary effusion lymphoma cells
-
Hussain AR, et al. (2007) Sanguinarine-dependent induction of apoptosis in primary effusion lymphoma cells. Cancer Res. 67:3888-97.
-
(2007)
Cancer Res.
, vol.67
, pp. 3888-3897
-
-
Hussain, A.R.1
-
25
-
-
0347719362
-
Differentiation stage-specific activation of p38 mitogen-activated protein kinase isoforms in primary human erythroid cells
-
Uddin S, Ah-Kang J, Ulaszek J, Mahmud D, Wickrema A. (2004) Differentiation stage-specific activation of p38 mitogen-activated protein kinase isoforms in primary human erythroid cells. Proc. Natl. Acad. Sci. U. S. A. 101:147-52.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 147-152
-
-
Uddin, S.1
Ah-Kang, J.2
Ulaszek, J.3
Mahmud, D.4
Wickrema, A.5
-
26
-
-
17144362835
-
Inhibition of phosphatidylinositol 33-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells
-
Uddin S, et al. (2005) Inhibition of phosphatidylinositol 33-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells. Clin. Cancer Res. 11:3102-8.
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 3102-3108
-
-
Uddin, S.1
-
27
-
-
19544389146
-
c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention
-
Christensen JG, Burrows J, Salgia R. (2005) c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention. Cancer Lett. 225:1-26.
-
(2005)
Cancer Lett.
, vol.225
, pp. 1-26
-
-
Christensen, J.G.1
Burrows, J.2
Salgia, R.3
-
28
-
-
30444451036
-
Functional analysis of HGF/MET signaling and aberrant HGF-activator expression in diffuse large B-cell lymphoma
-
Tjin EP, et al. (2006) Functional analysis of HGF/MET signaling and aberrant HGF-activator expression in diffuse large B-cell lymphoma. Blood. 107:760-8.
-
(2006)
Blood.
, vol.107
, pp. 760-768
-
-
Tjin, E.P.1
-
29
-
-
78650781733
-
HGF/c-Met pathway has a prominent role in mediating antiapoptotic signals through AKT in epithelial ovarian carcinoma
-
Bu R, et al. (2011) HGF/c-Met pathway has a prominent role in mediating antiapoptotic signals through AKT in epithelial ovarian carcinoma. Lab. Invest. 91:124-37.
-
(2011)
Lab. Invest.
, vol.91
, pp. 124-137
-
-
Bu, R.1
-
30
-
-
28144442013
-
Inhibition of the met receptor in mesothelioma
-
Mukohara T, et al. (2005) Inhibition of the met receptor in mesothelioma. Clin. Cancer Res. 11:8122-30.
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 8122-8130
-
-
Mukohara, T.1
-
31
-
-
77951245187
-
Gating of the mitochondrial permeability transition pore by long chain fatty acyl analogs in vivo
-
Samovski D, Kalderon B, Yehuda-Shnaidman E, Bar-Tana J. (2010) Gating of the mitochondrial permeability transition pore by long chain fatty acyl analogs in vivo. J. Biol. Chem. 285:6879-90.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 6879-6890
-
-
Samovski, D.1
Kalderon, B.2
Yehuda-Shnaidman, E.3
Bar-Tana, J.4
-
32
-
-
13244267274
-
Acute promyelocytic leukemia: Recent advances in therapy and molecular basis of response to arsenic therapies
-
Chou WC, Dang CV. (2005) Acute promyelocytic leukemia: recent advances in therapy and molecular basis of response to arsenic therapies. Curr. Opin. Hematol. 12:1-6.
-
(2005)
Curr. Opin. Hematol.
, vol.12
, pp. 1-6
-
-
Chou, W.C.1
Dang, C.V.2
-
33
-
-
27744609173
-
Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5)
-
Jung EM, Lim JH, Lee TJ, Park JW, Choi KS, Kwon TK. (2005) Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5). Carcinogenesis. 26:1905-13.
-
(2005)
Carcinogenesis.
, vol.26
, pp. 1905-1913
-
-
Jung, E.M.1
Lim, J.H.2
Lee, T.J.3
Park, J.W.4
Choi, K.S.5
Kwon, T.K.6
-
34
-
-
0038724909
-
c-Met: Structure, functions and potential for therapeutic inhibition
-
Ma PC, Maulik G, Christensen J, Salgia R. (2003) c-Met: structure, functions and potential for therapeutic inhibition. Cancer Metastasis Rev. 22:309-25.
-
(2003)
Cancer Metastasis Rev.
, vol.22
, pp. 309-325
-
-
Ma, P.C.1
Maulik, G.2
Christensen, J.3
Salgia, R.4
-
35
-
-
0034693753
-
Met receptor tyrosine kinase: Enhanced signaling through adapter proteins
-
Furge KA, Zhang YW, Vande Woude GF. (2000) Met receptor tyrosine kinase: enhanced signaling through adapter proteins. Oncogene. 19:5582-9.
-
(2000)
Oncogene.
, vol.19
, pp. 5582-5589
-
-
Furge, K.A.1
Zhang, Y.W.2
Vande Woude, G.F.3
-
36
-
-
33847746580
-
c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion
-
Sawada K, et al. (2007) c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion. Cancer Res. 67:1670-9.
-
(2007)
Cancer Res.
, vol.67
, pp. 1670-1679
-
-
Sawada, K.1
-
37
-
-
51749095291
-
Effect of a c-Met-specific, ATP-competitive small-molecule inhibitor SU11274 on human ovarian carcinoma cell growth, motility, and invasion
-
Koon EC, et al. (2008) Effect of a c-Met-specific, ATP-competitive small-molecule inhibitor SU11274 on human ovarian carcinoma cell growth, motility, and invasion. Int. J. Gynecol. Cancer. 18:976-84.
-
(2008)
Int. J. Gynecol. Cancer.
, vol.18
, pp. 976-984
-
-
Koon, E.C.1
-
38
-
-
0035793091
-
Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways
-
Xiao GH, Jeffers M, Bellacosa A, Mitsuuchi Y, Vande Woude GF, Testa JR. (2001) Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways. Proc. Natl. Acad. Sci. U. S. A. 98:247-52.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 247-252
-
-
Xiao, G.H.1
Jeffers, M.2
Bellacosa, A.3
Mitsuuchi, Y.4
Vande Woude, G.F.5
Testa, J.R.6
-
39
-
-
0033023940
-
Overexpression of c-Met protein in human thyroid tumors correlated with lymph node metastasis and clinicopathologic stage
-
Chen BK, et al. (1999) Overexpression of c-Met protein in human thyroid tumors correlated with lymph node metastasis and clinicopathologic stage. Pathol. Res. Pract. 195:427-33.
-
(1999)
Pathol. Res. Pract.
, vol.195
, pp. 427-433
-
-
Chen, B.K.1
-
40
-
-
0033731007
-
Over-expression of hepatocyte growth factor/scatter factor (HGF/SF) and the HGF/SF receptor (cMET) are associated with a high risk of metastasis and recurrence for children and young adults with papillary thyroid carcinoma
-
Ramirez R, et al. (2000) Over-expression of hepatocyte growth factor/scatter factor (HGF/SF) and the HGF/SF receptor (cMET) are associated with a high risk of metastasis and recurrence for children and young adults with papillary thyroid carcinoma. Clin. Endocrinol. 53:635-44.
-
(2000)
Clin. Endocrinol.
, vol.53
, pp. 635-644
-
-
Ramirez, R.1
-
41
-
-
50249160548
-
Small molecule c-MET inhibitor PHA665752: Effect on cell growth and motility in papillary thyroid carcinoma
-
Chattopadhyay C, El-Naggar AK, Williams MD, Clayman GL. (2008) Small molecule c-MET inhibitor PHA665752: effect on cell growth and motility in papillary thyroid carcinoma. Head Neck. 30:991-1000.
-
(2008)
Head Neck.
, vol.30
, pp. 991-1000
-
-
Chattopadhyay, C.1
El-Naggar, A.K.2
Williams, M.D.3
Clayman, G.L.4
-
42
-
-
39049169179
-
Clinicopathological analysis of papillary thyroid cancer with PIK3CA alterations in a Middle Eastern population
-
Abubaker J, et al. (2008) Clinicopathological analysis of papillary thyroid cancer with PIK3CA alterations in a Middle Eastern population. J. Clin. Endocrinol. Metab. 93:611-8.
-
(2008)
J. Clin. Endocrinol. Metab.
, vol.93
, pp. 611-618
-
-
Abubaker, J.1
-
43
-
-
33750627809
-
No evidence of ARAF, CRAF and MET mutations in BRAFT1799A negative human papillary thyroid carcinoma
-
Kumagai A, et al. (2006) No evidence of ARAF, CRAF and MET mutations in BRAFT1799A negative human papillary thyroid carcinoma. Endocr. J. 53:615-20.
-
(2006)
Endocr. J.
, vol.53
, pp. 615-620
-
-
Kumagai, A.1
-
44
-
-
14644437742
-
Mechanisms of resistance to TRAIL-induced apoptosis in cancer
-
Zhang L, Fang B. (2005) Mechanisms of resistance to TRAIL-induced apoptosis in cancer. Cancer Gene. Ther. 12:228-37.
-
(2005)
Cancer Gene. Ther.
, vol.12
, pp. 228-237
-
-
Zhang, L.1
Fang, B.2
|