메뉴 건너뛰기




Volumn 37, Issue 6, 2009, Pages 1978-1987

Lung injury after hemorrhage is age dependent: Role of peroxisome proliferator-activated receptor γ

Author keywords

Acute lung injury; Aging; Heat shock factor 1; Hemorrhage; Nuclear factor B; Peroxisome proliferator activated receptor

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; HEAT SHOCK TRANSCRIPTION FACTOR 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MYELOPEROXIDASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

EID: 66449130990     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31819feb4d     Document Type: Article
Times cited : (25)

References (53)
  • 1
    • 0036899210 scopus 로고    scopus 로고
    • The injured child is resistant to multiple organ failure: A different inflammatory response?
    • Calkins CM, Bensard DD, Moore EE, et al: The injured child is resistant to multiple organ failure: A different inflammatory response? J Trauma 2002; 53:1058-1063
    • (2002) J Trauma , vol.53 , pp. 1058-1063
    • Calkins, C.M.1    Bensard, D.D.2    Moore, E.E.3
  • 2
    • 0031710055 scopus 로고    scopus 로고
    • Multiple organ failure can be predicted as early as 12 hours after injury
    • Sauaia A, Moore FA, Moore EE, et al: Multiple organ failure can be predicted as early as 12 hours after injury. J Trauma 1998; 45: 291-301
    • (1998) J Trauma , vol.45 , pp. 291-301
    • Sauaia, A.1    Moore, F.A.2    Moore, E.E.3
  • 3
    • 0028918355 scopus 로고
    • Respiratory distress in traumatized and burned children
    • Scannell G, Waxman K, Tominaga GT: Respiratory distress in traumatized and burned children. J Pediatr Surg 1995; 30:612-614
    • (1995) J Pediatr Surg , vol.30 , pp. 612-614
    • Scannell, G.1    Waxman, K.2    Tominaga, G.T.3
  • 4
    • 0030750071 scopus 로고    scopus 로고
    • Systemic blood loss affects NF-κB regulatory mechanisms in the lungs
    • Moine P, Shenkar R, Aneko D, et al: Systemic blood loss affects NF-κB regulatory mechanisms in the lungs. Am J Physiol Lung Cell Mol Physiol 1997; 273:L185-L192
    • (1997) Am J Physiol Lung Cell Mol Physiol , vol.273
    • Moine, P.1    Shenkar, R.2    Aneko, D.3
  • 5
    • 0033565425 scopus 로고    scopus 로고
    • Mechanisms of lung neutrophil activation after hemorrhage or endotoxemia: Roles of reactive oxygen intermediates, NF-κB, and cyclic AMP response element binding protein
    • Shenkar R, Abraham E: Mechanisms of lung neutrophil activation after hemorrhage or endotoxemia: Roles of reactive oxygen intermediates, NF-κB, and cyclic AMP response element binding protein. J Immunol 1999; 163:954-962
    • (1999) J Immunol , vol.163 , pp. 954-962
    • Shenkar, R.1    Abraham, E.2
  • 6
    • 20244373188 scopus 로고    scopus 로고
    • HMGB1 contributes to the development of acute lung injury after hemorrhage
    • Kim JY, Park JS, Strassheim D, et al: HMGB1 contributes to the development of acute lung injury after hemorrhage. Am J Physiol Lung Cell Mol Physiol 2005; 288:L958-L965
    • (2005) Am J Physiol Lung Cell Mol Physiol , vol.288
    • Kim, J.Y.1    Park, J.S.2    Strassheim, D.3
  • 7
    • 33751580324 scopus 로고    scopus 로고
    • Heat shock response and acute lung injury
    • Wheeler DS, Wong HR: Heat shock response and acute lung injury. Free Radic Biol Med 2007; 42:1-14
    • (2007) Free Radic Biol Med , vol.42 , pp. 1-14
    • Wheeler, D.S.1    Wong, H.R.2
  • 8
    • 17644405062 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ is a new therapeutic target in sepsis and inflammation
    • Zingarelli B, Cook JA: Peroxisome proliferator-activated receptor-γ is a new therapeutic target in sepsis and inflammation. Shock 2005; 23:393-399
    • (2005) Shock , vol.23 , pp. 393-399
    • Zingarelli, B.1    Cook, J.A.2
  • 9
    • 0346366979 scopus 로고    scopus 로고
    • 2 and ciglitazone, reduces systemic inflammation in polymicrobial sepsis by modulation of signal transduction pathways
    • 2 and ciglitazone, reduces systemic inflammation in polymicrobial sepsis by modulation of signal transduction pathways. J Immunol 2003; 171:6827-6837
    • (2003) J Immunol , vol.171 , pp. 6827-6837
    • Zingarelli, B.1    Sheehan, M.2    Hake, P.W.3
  • 10
    • 21744458404 scopus 로고    scopus 로고
    • 2), a peroxisome proliferator activated receptor -γ ligand, reduces tissue leukosequestration and mortality in endotoxic shock
    • 2), a peroxisome proliferator activated receptor -γ ligand, reduces tissue leukosequestration and mortality in endotoxic shock. Shock 2005; 24:59-65
    • (2005) Shock , vol.24 , pp. 59-65
    • Kaplan, J.M.1    Cook, J.A.2    Hake, P.W.3
  • 11
    • 34247348681 scopus 로고    scopus 로고
    • Pro-insulin C-peptide exerts beneficial effects in endotoxic shock in mice
    • Vish MG, Hake PW, O'Connor M, et al: Pro-insulin C-peptide exerts beneficial effects in endotoxic shock in mice. Crit Care Med 2007; 35:1348-1355
    • (2007) Crit Care Med , vol.35 , pp. 1348-1355
    • Vish, M.G.1    Hake, P.W.2    O'Connor, M.3
  • 12
    • 26444600114 scopus 로고    scopus 로고
    • Rosiglitazone, a peroxisome proliferator-activated receptor-γ agonist, reduces acute lung injury in endotoxemic rats
    • Liu D, Zeng BX, Zhang SH, et al: Rosiglitazone, a peroxisome proliferator-activated receptor-γ agonist, reduces acute lung injury in endotoxemic rats. Crit Care Med 2005; 33:2309-2316
    • (2005) Crit Care Med , vol.33 , pp. 2309-2316
    • Liu, D.1    Zeng, B.X.2    Zhang, S.H.3
  • 13
    • 35248867156 scopus 로고    scopus 로고
    • 2 and ciglitazone, in reperfusion injury: Role of nuclear factor-κB, heat shock factor 1, and Akt
    • 2 and ciglitazone, in reperfusion injury: Role of nuclear factor-κB, heat shock factor 1, and Akt. Shock 2007; 28:554-563
    • (2007) Shock , vol.28 , pp. 554-563
    • Zingarelli, B.1    Hake, P.W.2    Mangeshkar, P.3
  • 14
    • 0030689044 scopus 로고    scopus 로고
    • Amelioration by mercaptoethylguanidine of the vascular, energetic failure in haemorrhagic shock in the anesthetised rat
    • Zingarelli B, Ischiropoulos H, Salzman AL, et al: Amelioration by mercaptoethylguanidine of the vascular, energetic failure in haemorrhagic shock in the anesthetised rat. Eur J Pharmacol 1997; 338:55-65.
    • (1997) Eur J Pharmacol , vol.338 , pp. 55-65
    • Zingarelli, B.1    Ischiropoulos, H.2    Salzman, A.L.3
  • 15
    • 0024267364 scopus 로고
    • Purified human factor activates heat shock promoter in a HeLa cell-free transcription system
    • Goldenberg CJ, Luo Y, Fenna M, et al: Purified human factor activates heat shock promoter in a HeLa cell-free transcription system. J Biol Chem 1988; 263:19734-19739
    • (1988) J Biol Chem , vol.263 , pp. 19734-19739
    • Goldenberg, C.J.1    Luo, Y.2    Fenna, M.3
  • 17
    • 0037247748 scopus 로고    scopus 로고
    • Nuclear factor-KB as a therapeutic target in critical care medicine
    • Zingarelli B, Sheehan M, Wong HR: Nuclear factor-KB as a therapeutic target in critical care medicine. Crit Care Med 2003; 31: S105-S111
    • (2003) Crit Care Med , vol.31
    • Zingarelli, B.1    Sheehan, M.2    Wong, H.R.3
  • 18
    • 0026341970 scopus 로고
    • Use of rodents as models for the study of "normal aging": Conceptual and practical issues
    • Masoro EJ: Use of rodents as models for the study of "normal aging": Conceptual and practical issues. Neurobiol Aging 1991; 12: 639-643
    • (1991) Neurobiol Aging , vol.12 , pp. 639-643
    • Masoro, E.J.1
  • 19
    • 0018870934 scopus 로고
    • Mortality and growth characteristics of rat strains commonly used in aging research
    • Masoro EJ: Mortality and growth characteristics of rat strains commonly used in aging research. Exp Aging Res 1980; 6:219-233
    • (1980) Exp Aging Res , vol.6 , pp. 219-233
    • Masoro, E.J.1
  • 20
    • 0038678097 scopus 로고    scopus 로고
    • Animal models for hemorrhage and resuscitation research
    • Majde JA: Animal models for hemorrhage and resuscitation research. J Trauma 2003; 54:S100-S105
    • (2003) J Trauma , vol.54
    • Majde, J.A.1
  • 21
    • 33646091523 scopus 로고    scopus 로고
    • Respective contribution of age, mean arterial pressure, and body weight on central arterial distensibility in SHR
    • Labat C, Cunha RS, Challande P, et al: Respective contribution of age, mean arterial pressure, and body weight on central arterial distensibility in SHR. Am J Physiol Heart Circ Physiol 2006; 290:H1534-H1539
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Labat, C.1    Cunha, R.S.2    Challande, P.3
  • 22
    • 7244230974 scopus 로고    scopus 로고
    • Left ventricular pressure-volume relationship in a rat model of advanced aging-associated heart failure
    • Pacher P, Mabley JG, Liaudet L, et al: Left ventricular pressure-volume relationship in a rat model of advanced aging-associated heart failure. Am J Physiol Heart Circ Physiol 2004; 287:H2132-H2137
    • (2004) Am J Physiol Heart Circ Physiol , vol.287
    • Pacher, P.1    Mabley, J.G.2    Liaudet, L.3
  • 23
    • 0031969854 scopus 로고    scopus 로고
    • Aging, changes in the cardiovascular system, and responses to stress
    • Weisfeldt M: Aging, changes in the cardiovascular system, and responses to stress. Am J Hypertens 1998; 11:41S-45S.
    • (1998) Am J Hypertens , vol.11
    • Weisfeldt, M.1
  • 24
    • 0031795412 scopus 로고    scopus 로고
    • Effects of aging on cardiac output, regional blood flow, and body composition in Fischer-344 rats
    • Delp MD, Evans MV, Duan C: Effects of aging on cardiac output, regional blood flow, and body composition in Fischer-344 rats. J Appl Physiol 1998; 85:1813-1822
    • (1998) J Appl Physiol , vol.85 , pp. 1813-1822
    • Delp, M.D.1    Evans, M.V.2    Duan, C.3
  • 25
    • 0027957198 scopus 로고
    • Early predictors of postinjury multiple organ failure
    • Sauaia A, Moore FA, Moore EE, et al: Early predictors of postinjury multiple organ failure. Arch Surg 1994; 129:39-45
    • (1994) Arch Surg , vol.129 , pp. 39-45
    • Sauaia, A.1    Moore, F.A.2    Moore, E.E.3
  • 26
    • 0030957958 scopus 로고    scopus 로고
    • Decreased expression of murine PPARγ in adipose tissue during endotoxemia
    • Hill MR, Young MD, McCurdy CM, et al: Decreased expression of murine PPARγ in adipose tissue during endotoxemia. Endocrinology 1997; 138:3073-3076
    • (1997) Endocrinology , vol.138 , pp. 3073-3076
    • Hill, M.R.1    Young, M.D.2    McCurdy, C.M.3
  • 27
    • 0942287345 scopus 로고    scopus 로고
    • Altered expression of nuclear hormone receptors and coactivators in mouse heart during the acute-phase response
    • Feingold K, Kim MS, Shigenaga J, et al: Altered expression of nuclear hormone receptors and coactivators in mouse heart during the acute-phase response. Am J Physiol Endocrinol Metab 2004; 286:E201-E207
    • (2004) Am J Physiol Endocrinol Metab , vol.286
    • Feingold, K.1    Kim, M.S.2    Shigenaga, J.3
  • 28
    • 33745632762 scopus 로고    scopus 로고
    • The antiinflammatory effect of curcumin in an experimental model of sepsis is mediated by up-regulation of peroxisome proliferator-activated receptor-γ
    • Siddiqui AM, Cui X, Wu R, et al: The antiinflammatory effect of curcumin in an experimental model of sepsis is mediated by up-regulation of peroxisome proliferator-activated receptor-γ. Crit Care Med 2006; 34:1874-1882
    • (2006) Crit Care Med , vol.34 , pp. 1874-1882
    • Siddiqui, A.M.1    Cui, X.2    Wu, R.3
  • 29
    • 33845312275 scopus 로고    scopus 로고
    • Downregu-lation of hepatic cytochrome P-450 isoforms and PPAR-γ: Their role in hepatic injury and proinflammatory responses in a double-hit model of hemorrhage and sepsis
    • Higuchi S, Wu R, Zhou M, et al: Downregu-lation of hepatic cytochrome P-450 isoforms and PPAR-γ: Their role in hepatic injury and proinflammatory responses in a double-hit model of hemorrhage and sepsis. J Surg Res 2007; 137:46-52
    • (2007) J Surg Res , vol.137 , pp. 46-52
    • Higuchi, S.1    Wu, R.2    Zhou, M.3
  • 30
    • 1242283852 scopus 로고    scopus 로고
    • Endogenous ligands of PPAR-γ reduce the liver injury in haemorrhagic shock
    • Collin M, Abdelrahman M, Thiemermann C: Endogenous ligands of PPAR-γ reduce the liver injury in haemorrhagic shock. Eur J Pharmacol 2004; 486:233-235
    • (2004) Eur J Pharmacol , vol.486 , pp. 233-235
    • Collin, M.1    Abdelrahman, M.2    Thiemermann, C.3
  • 32
    • 54549123726 scopus 로고    scopus 로고
    • Ciglitazone ameliorates lung inflammation by modulating the IKK/NF-κB pathway following hemorrhagic shock
    • Chima R, Hake P, Mangeshkar P, et al: Ciglitazone ameliorates lung inflammation by modulating the IKK/NF-κB pathway following hemorrhagic shock. Crit Care Med 2008; 36:2849-2857
    • (2008) Crit Care Med , vol.36 , pp. 2849-2857
    • Chima, R.1    Hake, P.2    Mangeshkar, P.3
  • 33
    • 0036088799 scopus 로고    scopus 로고
    • Ethyl pyruvate modulates inflammatory gene expression in mice subjected to hemorrhagic shock
    • Yang R, Gallo DJ, Baust JJ, et al: Ethyl pyruvate modulates inflammatory gene expression in mice subjected to hemorrhagic shock. Am J Physiol Gastrointest Liver Physiol 2002; 283:G212-G221
    • (2002) Am J Physiol Gastrointest Liver Physiol , vol.283
    • Yang, R.1    Gallo, D.J.2    Baust, J.J.3
  • 34
    • 17744399022 scopus 로고    scopus 로고
    • Calpain inhibitor I reduces the activation of nuclear factor-κB and organ injury/dysfunction in hemorrhagic shock
    • McDonald MC, Mota-Filipe H, Paul A, et al: Calpain inhibitor I reduces the activation of nuclear factor-κB and organ injury/dysfunction in hemorrhagic shock. FASEB J 2001; 15:171-186
    • (2001) FASEB J , vol.15 , pp. 171-186
    • McDonald, M.C.1    Mota-Filipe, H.2    Paul, A.3
  • 35
    • 85031352470 scopus 로고    scopus 로고
    • Zingarelli B, Hake PW, Burroughs T, et al: Parthenolide, an inhibitor of NF-κB, reduces the inflammatory response in hemorrhagic shock in the rat. In: Proceedings of The Sixth World Congress on Trauma, Shock, Inflammation and Sepsis - Pathophysiology, Immune Consequences and Therapy. Bologna, Italy, Medimond S.r.L, 2004, pp 193-198
    • Zingarelli B, Hake PW, Burroughs T, et al: Parthenolide, an inhibitor of NF-κB, reduces the inflammatory response in hemorrhagic shock in the rat. In: Proceedings of The Sixth World Congress on Trauma, Shock, Inflammation and Sepsis - Pathophysiology, Immune Consequences and Therapy. Bologna, Italy, Medimond S.r.L, 2004, pp 193-198
  • 36
    • 33746685009 scopus 로고    scopus 로고
    • Synergistic effect of peroxisome proliferator activated receptor-γ and liver X receptor-α in the regulation of inflammation in macrophages
    • Piraino G, Cook JA, O'Connor M, et al: Synergistic effect of peroxisome proliferator activated receptor-γ and liver X receptor-α in the regulation of inflammation in macrophages. Shock 2006; 26:146-153
    • (2006) Shock , vol.26 , pp. 146-153
    • Piraino, G.1    Cook, J.A.2    O'Connor, M.3
  • 37
    • 34249723602 scopus 로고    scopus 로고
    • Vascular smooth muscle and endothelial functions in aging
    • Yildiz O: Vascular smooth muscle and endothelial functions in aging. Ann NY Acad Sci 2007; 1100:353-360
    • (2007) Ann NY Acad Sci , vol.1100 , pp. 353-360
    • Yildiz, O.1
  • 38
    • 0037007075 scopus 로고    scopus 로고
    • Endothelial cell senescence in human atherosclerosis: Role of telomere in endothelial dysfunction
    • Minamino T, Miyauchi H, Yoshida T, et al: Endothelial cell senescence in human atherosclerosis: Role of telomere in endothelial dysfunction. Circulation 2002; 105: 1541-1544
    • (2002) Circulation , vol.105 , pp. 1541-1544
    • Minamino, T.1    Miyauchi, H.2    Yoshida, T.3
  • 39
    • 3242724976 scopus 로고    scopus 로고
    • The proinflammatory phenotype of senescent cells: The p53-mediated ICAM-1 expression
    • Kletsas D, Pratsinis H, Mariatos G, et al: The proinflammatory phenotype of senescent cells: The p53-mediated ICAM-1 expression. Ann NY Acad Sci 2004; 1019:330-332
    • (2004) Ann NY Acad Sci , vol.1019 , pp. 330-332
    • Kletsas, D.1    Pratsinis, H.2    Mariatos, G.3
  • 40
    • 0036021816 scopus 로고    scopus 로고
    • Time course of lung ischemia-reperfusion-induced ICAM-1 expression and its role in ischemia-reperfu-sion lung injury
    • Lu YT, Chen PG, Liu SF: Time course of lung ischemia-reperfusion-induced ICAM-1 expression and its role in ischemia-reperfu-sion lung injury. J Appl Physiol 2002; 93: 620-628
    • (2002) J Appl Physiol , vol.93 , pp. 620-628
    • Lu, Y.T.1    Chen, P.G.2    Liu, S.F.3
  • 41
    • 39049102441 scopus 로고    scopus 로고
    • Mechanical ventilation and hemorrhagic shock-resuscitation interact to increase inflammatory cytokine release in rats
    • Bouadma L, Dreyfuss D, Ricard JD, et al: Mechanical ventilation and hemorrhagic shock-resuscitation interact to increase inflammatory cytokine release in rats. Crit Care Med 2007; 35:2601-2606
    • (2007) Crit Care Med , vol.35 , pp. 2601-2606
    • Bouadma, L.1    Dreyfuss, D.2    Ricard, J.D.3
  • 42
    • 20044385081 scopus 로고    scopus 로고
    • In vivo gene silencing (with siRNA) of pulmonary expression of MIP-2 versus KC results in divergent effects on hemorrhage-induced, neutrophil-mediated septic acute lung injury
    • Lomas-Neira JL, Chung CS, Wesche DE, et al: In vivo gene silencing (with siRNA) of pulmonary expression of MIP-2 versus KC results in divergent effects on hemorrhage-induced, neutrophil-mediated septic acute lung injury. J Leukoc Biol 2005; 77: 846-853
    • (2005) J Leukoc Biol , vol.77 , pp. 846-853
    • Lomas-Neira, J.L.1    Chung, C.S.2    Wesche, D.E.3
  • 43
    • 0028101410 scopus 로고
    • Long-term impaired neutrophil migration in mice overexpressing human interleukin-8
    • Simonet WS, Hughes TM, Nguyen HQ, et al: Long-term impaired neutrophil migration in mice overexpressing human interleukin-8. J Clin Invest 1994; 94:1310-1319
    • (1994) J Clin Invest , vol.94 , pp. 1310-1319
    • Simonet, W.S.1    Hughes, T.M.2    Nguyen, H.Q.3
  • 44
    • 0141958059 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 (MCP-1) and macrophage infiltration into the skin after burn injury in aged mice
    • Shallo H, Plackett TP, Heinrich SA, et al: Monocyte chemoattractant protein-1 (MCP-1) and macrophage infiltration into the skin after burn injury in aged mice. Bums 2003; 29: 641-647
    • (2003) Bums , vol.29 , pp. 641-647
    • Shallo, H.1    Plackett, T.P.2    Heinrich, S.A.3
  • 45
    • 0038303680 scopus 로고    scopus 로고
    • Oxygen supply modulates MCP-1 release in monocytes from young and aged rats: Decrease of MCP-1 transcription and translation is age-related
    • Reale M, Di Giulio C, Cacchio M, et al: Oxygen supply modulates MCP-1 release in monocytes from young and aged rats: Decrease of MCP-1 transcription and translation is age-related. Mol Cell Biochem 2003; 248:1-6
    • (2003) Mol Cell Biochem , vol.248 , pp. 1-6
    • Reale, M.1    Di Giulio, C.2    Cacchio, M.3
  • 46
    • 0035885357 scopus 로고    scopus 로고
    • Different IL-8 production by T and NK lymphocytes in elderly subjects
    • Mariani E, Pulsatelli L, Meneghetti A, et al: Different IL-8 production by T and NK lymphocytes in elderly subjects. Mech Ageing Dev 2001; 122:1383-1395
    • (2001) Mech Ageing Dev , vol.122 , pp. 1383-1395
    • Mariani, E.1    Pulsatelli, L.2    Meneghetti, A.3
  • 47
    • 0032812761 scopus 로고    scopus 로고
    • Transcriptional regulation of the heat shock protein genes by STAT family transcription factors
    • Stephanou A, Latchman DS: Transcriptional regulation of the heat shock protein genes by STAT family transcription factors. Gene Expr 1999; 7:311-319
    • (1999) Gene Expr , vol.7 , pp. 311-319
    • Stephanou, A.1    Latchman, D.S.2
  • 48
    • 0032608038 scopus 로고    scopus 로고
    • Heat shock proteins: Facts, thoughts, and dreams
    • De Maio A: Heat shock proteins: Facts, thoughts, and dreams. Shock 1999; 11:1-12
    • (1999) Shock , vol.11 , pp. 1-12
    • De Maio, A.1
  • 49
    • 0024359486 scopus 로고
    • Attenuated induction of heat shock gene expression in aging diploid fibroblasts
    • Liu AY, Lin Z, Choi HS, et al: Attenuated induction of heat shock gene expression in aging diploid fibroblasts. J Biol Chem 1989; 264:12037-12045
    • (1989) J Biol Chem , vol.264 , pp. 12037-12045
    • Liu, A.Y.1    Lin, Z.2    Choi, H.S.3
  • 51
    • 0029750727 scopus 로고    scopus 로고
    • with antiviral activity. J Biol Chem 1996; 271:32192-32196
    • with antiviral activity. J Biol Chem 1996; 271:32192-32196
  • 52
    • 33847093475 scopus 로고    scopus 로고
    • Thiazolidinedione class of peroxisome proliferator-activated receptor γ agonists prevents neuronal damage, motor dysfunction, myelin loss, neuropathic pain, and inflammation after spinal cord injury in adult rats
    • Park SW, Yi JH, Miranpuri G, et al: Thiazolidinedione class of peroxisome proliferator-activated receptor γ agonists prevents neuronal damage, motor dysfunction, myelin loss, neuropathic pain, and inflammation after spinal cord injury in adult rats. J Pharmacol Exp Ther 2007; 320:1002-1012
    • (2007) J Pharmacol Exp Ther , vol.320 , pp. 1002-1012
    • Park, S.W.1    Yi, J.H.2    Miranpuri, G.3
  • 53
    • 29544435794 scopus 로고    scopus 로고
    • Pioglitazone, a specific ligand of peroxisome proliferator-activated receptor-γ, protects pancreas against acute cerulein-induced pancreatitis
    • Konturek PC, Dembinski A, Warzecha Z, et al: Pioglitazone, a specific ligand of peroxisome proliferator-activated receptor-γ, protects pancreas against acute cerulein-induced pancreatitis. World J Gastroenterol 2005; 11:6322-6329
    • (2005) World J Gastroenterol , vol.11 , pp. 6322-6329
    • Konturek, P.C.1    Dembinski, A.2    Warzecha, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.