Antifungal miconazole induces cardiotoxicity via inhibition of APE/Ref-1-related pathway in rat neonatal cardiomyocytes

Toxicological Sciences

Volumn 126, Issue 2, 2012, Pages 298-305

  Won, Kyung Jong ^a   Lin, Hai Yue ^a   Jung, Soohyun ^a   Cho, Soo Min ^b   Shin, Ho Chul ^b   Bae, Young Min ^a   Lee, Seung Hyun ^a   Kim, Hyun Jung ^a   Jeon, Byeong Hwa ^c   Kim, Bokyung ^a  

^a Konkuk University School of Medicine   (South Korea)

^b Konkuk University   (South Korea)

^c Chungnam National University   (South Korea)

Author keywords

Antifungal miconazole; APE Ref 1; Cardiotoxicity; DNA microarray

Indexed keywords

DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; MICONAZOLE; OXYGEN; REACTIVE OXYGEN METABOLITE; REDOX EFFECTOR FACTOR 1; SUPEROXIDE; TRANSCRIPTOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CARDIOTOXICITY; CONTROLLED STUDY; DNA MICROARRAY; GENE OVEREXPRESSION; GENETIC ANALYSIS; GENETIC TRANSFECTION; HEART MUSCLE CELL; HOMEOSTASIS; NEWBORN; NONHUMAN; OXIDATIVE STRESS; RAT; RECEPTOR DOWN REGULATION; UPREGULATION;

RATTUS;

EID: 84859029065     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr347     Document Type: Article

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