Cationic solid-lipid nanoparticles can efficiently bind and transfect plasmid DNA

Journal of Controlled Release

Volumn 77, Issue 3, 2001, Pages 345-355

  Olbrich, Carsten ^a   Bakowsky, Udo ^b   Lehr, Claus Michael ^c   Müller, Rainer H ^a   Kneuer, Carsten ^c  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

^c SAARLAND UNIVERSITY   (Germany)

Author keywords

Atomic force microscopy; Gene therapy; Nanoparticles; Nonviral DNA vectors; Solid lipid nanoparticles

Indexed keywords

CATION; CETYLPYRIDINIUM SALT; CHLOROQUINE; DRUG CARRIER; GALACTOSIDASE; GLYCEROL BEHENATE; LACTATE DEHYDROGENASE; LIPID; PARAFFIN; PLASMID DNA; POLYSORBATE 80; SOLID LIPID NANOPARTICLE; SORBITAN TRIOLEATE;

AGAR GEL ELECTROPHORESIS; ANIMAL CELL; ARTICLE; ATOMIC FORCE MICROSCOPY; CELL STRAIN COS1; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOMEGALOVIRUS; CYTOTOXICITY; DNA BINDING; DNA TRANSFECTION; DRUG EFFICACY; ENZYME ASSAY; ENZYME RELEASE; GENE TARGETING; IMAGE ANALYSIS; IN VITRO STUDY; LD 50; MOLECULAR SIZE; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; ZETA POTENTIAL;

ANIMALS; BINDING SITES; CATIONS; CELL SURVIVAL; CETYLPYRIDINIUM; CHLOROQUINE; COS CELLS; DNA, SUPERHELICAL; LIPID METABOLISM; LIPIDS; MACROMOLECULAR SUBSTANCES; MICROSCOPY, ATOMIC FORCE; MICROSPHERES; PARAFFIN; PLASMIDS; SURFACE-ACTIVE AGENTS; TRANSFECTION;

EID: 0035856764     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(01)00506-5     Document Type: Article

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