The human gastric cancer-associated DNA polymerase β variant D160N is a mutator that induces cellular transformation

DNA Repair

Volumn 11, Issue 4, 2012, Pages 381-390

  Donigan, Katherine A ^a   Hile, Suzanne E ^b   Eckert, Kristin A ^b   Sweasy, Joann B ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PENN STATE CANCER INSTITUTE   (United States)

Author keywords

Base excision repair; Cancer; Polymerase beta

Indexed keywords

DNA DIRECTED DNA POLYMERASE BETA;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CELL TRANSFORMATION; CONTROLLED STUDY; GENE EXPRESSION; GENE MUTATION; GENOMIC INSTABILITY; HUMAN; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; STOMACH CANCER; TUMOR GROWTH;

AMINO ACID SUBSTITUTION; ANIMALS; BASE SEQUENCE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; DNA; DNA LIGASES; DNA POLYMERASE BETA; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOMIC INSTABILITY; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; NEOPLASM INVASIVENESS; PHENOTYPE; STOMACH NEOPLASMS;

EID: 84859006366     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2012.01.004     Document Type: Article

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