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Volumn 435, Issue 2, 1999, Pages 121-128

Functional mutation of DNA polymerase β found in human gastric cancer - Inability of the base excision repair in vitro

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE BETA;

EID: 0032748078     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0921-8777(99)00036-1     Document Type: Article
Times cited : (66)

References (37)
  • 1
    • 0029943449 scopus 로고    scopus 로고
    • Mismatch repair in replication fidelity, genetic recombination, and cancer biology
    • Modrich P., Lahue R. Mismatch repair in replication fidelity, genetic recombination, and cancer biology. Annu. Rev. Biochem. 65:1996;101-133.
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 101-133
    • Modrich, P.1    Lahue, R.2
  • 2
    • 0027278557 scopus 로고
    • Instability and decay of the primary structure of DNA
    • see comments
    • Lindahl T. Instability and decay of the primary structure of DNA. Nature. 362:1993;709-715. see comments.
    • (1993) Nature , vol.362 , pp. 709-715
    • Lindahl, T.1
  • 3
    • 0029892791 scopus 로고    scopus 로고
    • DNA repair in eukaryotes
    • Wood R.D. DNA repair in eukaryotes. Annu. Rev. Biochem. 65:1996;135-167.
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 135-167
    • Wood, R.D.1
  • 4
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt M.S., Bennett W.P., Hollstein M., Harris C.C. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res. 54:1994;4855-4878.
    • (1994) Cancer Res. , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 5
    • 0025314841 scopus 로고
    • Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of GT mispairs in nuclear extracts from human cells
    • Wiebauer K., Jiricny J. Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of GT mispairs in nuclear extracts from human cells. Proc. Natl. Acad. Sci. U.S.A. 87:1990;5842-5845.
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 5842-5845
    • Wiebauer, K.1    Jiricny, J.2
  • 6
    • 0030030379 scopus 로고    scopus 로고
    • Requirement of mammalian DNA polymerase-beta in base-excision repair
    • published errata appear in Nature 1996 Feb 29; 379 (6568) 848 and 1996 Oct 3; 383 (6599) 457
    • Sobol R.W., Horton J.K., Kuhn R., Gu H., Singhal R.K., Prasad R., Rajewsky K., Wilson S.H. Requirement of mammalian DNA polymerase-beta in base-excision repair. Nature. 379:1996;183-186. published errata appear in Nature 1996 Feb 29; 379 (6568) 848 and 1996 Oct 3; 383 (6599) 457.
    • (1996) Nature , vol.379 , pp. 183-186
    • Sobol, R.W.1    Horton, J.K.2    Kuhn, R.3    Gu, H.4    Singhal, R.K.5    Prasad, R.6    Rajewsky, K.7    Wilson, S.H.8
  • 7
    • 0025826051 scopus 로고
    • Eukaryotic DNA polymerases
    • Wang T.S. Eukaryotic DNA polymerases. Annu. Rev. Biochem. 60:1991;513-552.
    • (1991) Annu. Rev. Biochem. , vol.60 , pp. 513-552
    • Wang, T.S.1
  • 8
    • 0023699975 scopus 로고
    • Characterization of DNA polymerase beta mRNA: Cell-cycle and growth response in cultured human cells
    • Zmudzka B.Z., Fornace A., Collins J., Wilson S.H. Characterization of DNA polymerase beta mRNA: cell-cycle and growth response in cultured human cells. Nucleic Acids Res. 16:1988;9587-9596.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 9587-9596
    • Zmudzka, B.Z.1    Fornace, A.2    Collins, J.3    Wilson, S.H.4
  • 9
    • 0025088519 scopus 로고
    • Studies of the domain structure of mammalian DNA polymerase beta. Identification of a discrete template binding domain
    • Kumar A., Widen S.G., Williams K.R., Kedar P., Karpel R.L., Wilson S.H. Studies of the domain structure of mammalian DNA polymerase beta. Identification of a discrete template binding domain. J. Biol. Chem. 265:1990;2124-2131.
    • (1990) J. Biol. Chem. , vol.265 , pp. 2124-2131
    • Kumar, A.1    Widen, S.G.2    Williams, K.R.3    Kedar, P.4    Karpel, R.L.5    Wilson, S.H.6
  • 10
    • 0025333457 scopus 로고
    • Identification and properties of the catalytic domain of mammalian DNA polymerase beta
    • Kumar A., Abbotts J., Karawya E.M., Wilson S.H. Identification and properties of the catalytic domain of mammalian DNA polymerase beta. Biochemistry. 29:1990;7156-7159.
    • (1990) Biochemistry , vol.29 , pp. 7156-7159
    • Kumar, A.1    Abbotts, J.2    Karawya, E.M.3    Wilson, S.H.4
  • 11
    • 0029028964 scopus 로고
    • Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair
    • Matsumoto Y., Kim K. Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair. Science. 269:1995;699-702.
    • (1995) Science , vol.269 , pp. 699-702
    • Matsumoto, Y.1    Kim, K.2
  • 12
    • 0026541430 scopus 로고
    • Mammalian DNA polymerase beta can substitute for DNA polymerase I during DNA replication in Escherichia coli
    • Sweasy J.B., Loeb L.A. Mammalian DNA polymerase beta can substitute for DNA polymerase I during DNA replication in Escherichia coli. J. Biol. Chem. 267:1992;1407-1410.
    • (1992) J. Biol. Chem. , vol.267 , pp. 1407-1410
    • Sweasy, J.B.1    Loeb, L.A.2
  • 13
    • 0028218705 scopus 로고
    • Enhanced repair of a cisplatin-damaged reporter chloramphenicol-O-acetyltransferase gene and altered activities of DNA polymerases alpha and beta, and DNA ligase in cells of a human malignant glioma following in vivo cisplatin therapy
    • Ali O.F., Berger M.S., Rairkar A., Stein D.E. Enhanced repair of a cisplatin-damaged reporter chloramphenicol-O-acetyltransferase gene and altered activities of DNA polymerases alpha and beta, and DNA ligase in cells of a human malignant glioma following in vivo cisplatin therapy. J. Cell Biochem. 54:1994;11-19.
    • (1994) J. Cell Biochem. , vol.54 , pp. 11-19
    • Ali, O.F.1    Berger, M.S.2    Rairkar, A.3    Stein, D.E.4
  • 15
    • 0028059099 scopus 로고
    • Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
    • see comments
    • Gu H., Marth J.D., Orban P.C., Mossmann H., Rajewsky K. Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science. 265:1994;103-106. see comments.
    • (1994) Science , vol.265 , pp. 103-106
    • Gu, H.1    Marth, J.D.2    Orban, P.C.3    Mossmann, H.4    Rajewsky, K.5
  • 16
    • 0028966181 scopus 로고
    • DNA polymerase beta conducts the gap-filling step in uracil-initiated base excision repair in a bovine testis nuclear extract
    • Singhal R.K., Prasad R., Wilson S.H. DNA polymerase beta conducts the gap-filling step in uracil-initiated base excision repair in a bovine testis nuclear extract. J. Biol. Chem. 270:1995;949-957.
    • (1995) J. Biol. Chem. , vol.270 , pp. 949-957
    • Singhal, R.K.1    Prasad, R.2    Wilson, S.H.3
  • 17
    • 0032100860 scopus 로고    scopus 로고
    • Mammalian base excision repair and DNA polymerase beta
    • Wilson S.H. Mammalian base excision repair and DNA polymerase beta. Mutat. Res. 407:1998;203-215.
    • (1998) Mutat. Res. , vol.407 , pp. 203-215
    • Wilson, S.H.1
  • 18
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 22
    • 0023850352 scopus 로고
    • SR alpha promoter: An efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat
    • Takebe Y., Seiki M., Fujisawa J., Hoy P., Yokota K., Arai K., Yoshida M., Arai N. SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat. Mol. Cell Biol. 8:1988;466-472.
    • (1988) Mol. Cell Biol. , vol.8 , pp. 466-472
    • Takebe, Y.1    Seiki, M.2    Fujisawa, J.3    Hoy, P.4    Yokota, K.5    Arai, K.6    Yoshida, M.7    Arai, N.8
  • 23
    • 0025807794 scopus 로고
    • Mammalian beta-polymerase promoter: Large-scale purification and properties of ATF/CREB palindrome binding protein from bovine testes
    • Widen S.G., Wilson S.H. Mammalian beta-polymerase promoter: large-scale purification and properties of ATF/CREB palindrome binding protein from bovine testes. Biochemistry. 30:1991;6296-6305.
    • (1991) Biochemistry , vol.30 , pp. 6296-6305
    • Widen, S.G.1    Wilson, S.H.2
  • 25
    • 0025868854 scopus 로고
    • Monoclonal antibodies recognizing amino-terminal and carboxy-terminal regions of human aldolase A: Probes to detect conformational changes of the enzyme
    • Kitajima Y., Matsuhashi S., Nishida H., Takasaki Y., Takahashi I., Hisatsugu T., Hori K. Monoclonal antibodies recognizing amino-terminal and carboxy-terminal regions of human aldolase A: probes to detect conformational changes of the enzyme. J. Biochem. (Tokyo). 109:1991;544-550.
    • (1991) J. Biochem. (Tokyo) , vol.109 , pp. 544-550
    • Kitajima, Y.1    Matsuhashi, S.2    Nishida, H.3    Takasaki, Y.4    Takahashi, I.5    Hisatsugu, T.6    Hori, K.7
  • 26
    • 0028136070 scopus 로고
    • Crystal structure of rat DNA polymerase beta: Evidence for a common polymerase mechanism
    • Sawaya M.R., Pelletier H., Kumar A., Wilson S.H., Kraut J. Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanism. Science. 264:1994;1930-1935.
    • (1994) Science , vol.264 , pp. 1930-1935
    • Sawaya, M.R.1    Pelletier, H.2    Kumar, A.3    Wilson, S.H.4    Kraut, J.5
  • 27
    • 0032485858 scopus 로고    scopus 로고
    • Catalytic center of DNA polymerase beta for excision of deoxyribose phosphate groups
    • Matsumoto Y., Kim K., Katz D.S., Feng J.A. Catalytic center of DNA polymerase beta for excision of deoxyribose phosphate groups. Biochemistry. 37:1998;6456-6464.
    • (1998) Biochemistry , vol.37 , pp. 6456-6464
    • Matsumoto, Y.1    Kim, K.2    Katz, D.S.3    Feng, J.A.4
  • 28
    • 0028787049 scopus 로고
    • Structure-function analysis of the mammalian DNA polymerase beta active site: Role of aspartic acid 256, arginine 254, and arginine 258 in nucleotidyl transfer
    • Menge K.L., Hostomsky Z., Nodes B.R., Hudson G.O., Rahmati S., Moomaw E.W., Almassy R.J., Hostomska Z. Structure-function analysis of the mammalian DNA polymerase beta active site: role of aspartic acid 256, arginine 254, and arginine 258 in nucleotidyl transfer. Biochemistry. 34:1995;15934-15942.
    • (1995) Biochemistry , vol.34 , pp. 15934-15942
    • Menge, K.L.1    Hostomsky, Z.2    Nodes, B.R.3    Hudson, G.O.4    Rahmati, S.5    Moomaw, E.W.6    Almassy, R.J.7    Hostomska, Z.8
  • 29
    • 0025836159 scopus 로고
    • Aspartic acid residues at positions 190 and 192 of rat DNA polymerase beta are involved in primer binding
    • Date T., Yamamoto S., Tanihara K., Nishimoto Y., Matsukage A. Aspartic acid residues at positions 190 and 192 of rat DNA polymerase beta are involved in primer binding. Biochemistry. 30:1991;5286-5292.
    • (1991) Biochemistry , vol.30 , pp. 5286-5292
    • Date, T.1    Yamamoto, S.2    Tanihara, K.3    Nishimoto, Y.4    Matsukage, A.5
  • 30
    • 0028049441 scopus 로고
    • Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP
    • see comments
    • Pelletier H., Sawaya M.R., Kumar A., Wilson S.H., Kraut J. Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP. Science. 264:1994;1891-1903. see comments.
    • (1994) Science , vol.264 , pp. 1891-1903
    • Pelletier, H.1    Sawaya, M.R.2    Kumar, A.3    Wilson, S.H.4    Kraut, J.5
  • 32
    • 0029064878 scopus 로고
    • Characterization of DNA polymerase beta mutants with amino acid substitutions located in the C-terminal portion of the enzyme
    • Sweasy J.B., Yoon M.S. Characterization of DNA polymerase beta mutants with amino acid substitutions located in the C-terminal portion of the enzyme. Mol. Gen. Genet. 248:1995;217-224.
    • (1995) Mol. Gen. Genet. , vol.248 , pp. 217-224
    • Sweasy, J.B.1    Yoon, M.S.2
  • 33
    • 0032562169 scopus 로고    scopus 로고
    • The mutator form of polymerase beta with amino acid substitution at tyrosine 265 in the hinge region displays an increase in both base substitution and frame shift errors
    • Opresko P.L., Sweasy J.B., Eckert K.A. The mutator form of polymerase beta with amino acid substitution at tyrosine 265 in the hinge region displays an increase in both base substitution and frame shift errors. Biochemistry. 37:1998;2111-2119.
    • (1998) Biochemistry , vol.37 , pp. 2111-2119
    • Opresko, P.L.1    Sweasy, J.B.2    Eckert, K.A.3
  • 34
    • 0032080334 scopus 로고    scopus 로고
    • Functional analysis of the amino-terminal 8-kDa domain of DNA polymerase beta as revealed by site-directed mutagenesis. DNA binding and 5′-deoxyribose phosphate lyase activities
    • Prasad R., Beard W.A., Chyan J.Y., Maciejewski M.W., Mullen G.P., Wilson S.H. Functional analysis of the amino-terminal 8-kDa domain of DNA polymerase beta as revealed by site-directed mutagenesis. DNA binding and 5′-deoxyribose phosphate lyase activities. J. Biol. Chem. 273:1998;11121-11126.
    • (1998) J. Biol. Chem. , vol.273 , pp. 11121-11126
    • Prasad, R.1    Beard, W.A.2    Chyan, J.Y.3    Maciejewski, M.W.4    Mullen, G.P.5    Wilson, S.H.6
  • 35
    • 0030930760 scopus 로고    scopus 로고
    • Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: Evidence for an induced fit mechanism
    • Sawaya M.R., Prasad R., Wilson S.H., Kraut J., Pelletier H. Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism. Biochemistry. 36:1997;11205-11215.
    • (1997) Biochemistry , vol.36 , pp. 11205-11215
    • Sawaya, M.R.1    Prasad, R.2    Wilson, S.H.3    Kraut, J.4    Pelletier, H.5
  • 36
    • 0026671855 scopus 로고
    • DNA polymerase beta mutations in human colorectal cancer
    • Wang L., Patel U., Ghosh L., Banerjee S. DNA polymerase beta mutations in human colorectal cancer. Cancer Res. 52:1992;4824-4827.
    • (1992) Cancer Res. , vol.52 , pp. 4824-4827
    • Wang, L.1    Patel, U.2    Ghosh, L.3    Banerjee, S.4
  • 37
    • 0030885254 scopus 로고    scopus 로고
    • A variant of DNA polymerase beta acts as a dominant negative mutant
    • Bhattacharyya N., Banerjee S. A variant of DNA polymerase beta acts as a dominant negative mutant. Proc. Natl. Acad. Sci. U.S.A. 94:1997;10324-10329.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 10324-10329
    • Bhattacharyya, N.1    Banerjee, S.2


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