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Volumn 46, Issue 1, 2012, Pages 68-74

Pituitary adenylate cyclase-activating polypeptide causes increased tyrosine phosphorylation of focal adhesion kinase and paxillin

Author keywords

FAK; Lung cancer; PACAP; Paxillin; Signal transduction; Tyrosine phosphorylation

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOCHALASIN D; FOCAL ADHESION KINASE; GENISTEIN; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE 27; PAXILLIN; PHOSPHATIDYLINOSITOL; PHOSPHOLIPASE C; PROTEIN TYROSINE KINASE; TYROSINE; VASOACTIVE INTESTINAL POLYPEPTIDE;

EID: 84858866010     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-011-9639-7     Document Type: Article
Times cited : (5)

References (51)
  • 2
    • 0026593319 scopus 로고
    • Pituitary adenylate cyclase activating polypeptide (PACAP): Discovery and current status of research
    • Arimura A (1992) Pituitary adenylate cyclase activating polypeptide (PACAP): discovery and current status of research. Regul Pept 37:287-303
    • (1992) Regul Pept , vol.37 , pp. 287-303
    • Arimura, A.1
  • 3
    • 0030793696 scopus 로고    scopus 로고
    • Adhesion of fibroblasts to fibronectin stimulates both serine and tyrosine phosphorylation of paxillin
    • Bellis SL, Perotta JA, Curtis MS, Turner CE (1997) Adhesion of fibroblasts to fibronectin stimulates both serine and tyrosine phosphorylation of paxillin. Biochem J 325:375-381 (Pubitemid 27338716)
    • (1997) Biochemical Journal , vol.325 , Issue.2 , pp. 375-381
    • Bellis, S.L.1    Perrotta, J.A.2    Curtis, M.S.3    Turner, C.E.4
  • 4
    • 0029961485 scopus 로고    scopus 로고
    • Genistein-stimulated adherence of prostate cancer cells is associated with the binding of focal adhesion kinase to beta-1-integrin
    • DOI 10.1007/BF00123398
    • Bergan R, Kyle E, Nguyen P, Trepel J, Neckers L (1996) Genistein-stimulated adherence of prostate cancer cells is associated with the binding of focal adhesion kinase to beta-1-integrin. Clin Exp Metastasis 14:389-398 (Pubitemid 26363213)
    • (1996) Clinical and Experimental Metastasis , vol.14 , Issue.4 , pp. 389-398
    • Bergan, R.1    Kyle, E.2    Nguyen, P.3    Trepel, J.4    Ingui, C.5    Neckers, L.6
  • 5
    • 0026445719 scopus 로고
    • Tyrosine phosphorylation of paxillin and p125FAK accompanies cell adhesion to extracellular matrix: A role in cytoskeletal assembly
    • Burridge K, Turner CE, Romer LH (1992) Tyrosine phosphorylation of paxillin and p125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly. J Cell Biol 119:893-903
    • (1992) J Cell Biol , vol.119 , pp. 893-903
    • Burridge, K.1    Turner, C.E.2    Romer, L.H.3
  • 7
    • 0032509565 scopus 로고    scopus 로고
    • Identification of p130(Cas) as a mediator of focal adhesion kinase- promoted cell migration
    • DOI 10.1083/jcb.140.1.211
    • Cary LS, Han DC, Poite TR, Hanks SK, Fuan JL (1998) Identification of p130Cas as a mediator of focal adhesion kinase-prompted cell migration. J Cell Biol 140:211-221 (Pubitemid 28070908)
    • (1998) Journal of Cell Biology , vol.140 , Issue.1 , pp. 211-221
    • Cary, L.A.1    Han, D.C.2    Polte, T.R.3    Hanks, S.K.4    Guan, J.-L.5
  • 8
    • 0029995797 scopus 로고    scopus 로고
    • Rho-stimulated contractility drives the formation of stress fibers and focal adhesions
    • Chrzanowski-Wodnick M, Burridge K (1996) Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. J Cell Biol 133:1403-1415
    • (1996) J Cell Biol , vol.133 , pp. 1403-1415
    • Chrzanowski-Wodnick, M.1    Burridge, K.2
  • 9
    • 0023427610 scopus 로고
    • Effects of cytochalasin and phalloidin on actin
    • Cooper JA (1987) Effects of cytochalasin and phalloidin on actin. J Cell Biol 105:1473-1478
    • (1987) J Cell Biol , vol.105 , pp. 1473-1478
    • Cooper, J.A.1
  • 10
    • 0030055986 scopus 로고    scopus 로고
    • PACAP stimulates c-fos mRNAs in small cell lung cancer cells
    • DOI 10.1016/0024-3205(96)00299-8
    • Draoui M, Hida T, Birrer M, Zia F, Moody TW (1996) PACAP stimulates c-fos mRNAs in small cell lung cancer cells. Life Sci 59(4):307-313 (Pubitemid 26232868)
    • (1996) Life Sciences , vol.59 , Issue.4 , pp. 307-313
    • Draoui, M.1    Hida, T.2    Jakowlew, S.3    Birrer, M.4    Zia, F.5    Moody, T.W.6
  • 11
    • 27344431757 scopus 로고    scopus 로고
    • The neuropeptide pituitary adenylate cyclase activating protein is a physiological activator of human monocytes
    • DOI 10.1016/j.cellsig.2005.03.027, PII S0898656805000781
    • El Zein N, Corazza F, Sariban E (2006) The neuropeptide pituitary adenylate cyclase activating protein is a physiological activator of human monocytes. Cell Signal 18:162-173 (Pubitemid 41527160)
    • (2006) Cellular Signalling , vol.18 , Issue.2 , pp. 162-173
    • El, Z.N.1    Corazza, F.2    Sariban, E.3
  • 12
    • 73849117889 scopus 로고    scopus 로고
    • PACAP induces signaling and stimulation of 5-hydroxytryptamine release and growth in neuroendocrine tumor cells
    • Germano PM, Lieu SN, Xue J, Cooke HJ, Christoff GL, Ly Y, Pisegna JR (2009) PACAP induces signaling and stimulation of 5-hydroxytryptamine release and growth in neuroendocrine tumor cells. J Mol Neurosci 39(3):391-401
    • (2009) J Mol Neurosci , vol.39 , Issue.3 , pp. 391-401
    • Germano, P.M.1    Lieu, S.N.2    Xue, J.3    Cooke, H.J.4    Christoff, G.L.5    Ly, Y.6    Pisegna, J.R.7
  • 13
    • 0026674919 scopus 로고
    • Focal adhesion protein-tyrosine phosphorylation in response to cell attachment to fibronectin
    • Hanks SK, Calab MD, Harper MC, Patel SK (1992) Focal adhesion protein-tyrosine phosphorylation in response to cell attachment to fibronectin. Proc Natl Acad Sci USA 89:8487-8491
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 8487-8491
    • Hanks, S.K.1    Calab, M.D.2    Harper, M.C.3    Patel, S.K.4
  • 14
    • 0029955660 scopus 로고    scopus 로고
    • An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase
    • Hildebrand JD, Taylor JM, Parsons JT (1996) An SH3 domain containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase. Mol Cell Biol 16:3169-3178 (Pubitemid 26163383)
    • (1996) Molecular and Cellular Biology , vol.16 , Issue.6 , pp. 3169-3178
    • Hildebrand, J.D.1    Taylor, J.M.2    Thomas, P.J.3
  • 15
    • 0026511295 scopus 로고
    • Functional expression and tissue distribuiton of a novel receptor for vasoactive intestinal polypeptide
    • Ishihara T, Shigemoto R, Mori K, Takahashi K, Nagata S (1992) Functional expression and tissue distribuiton of a novel receptor for vasoactive intestinal polypeptide. Neuron 8:811-819
    • (1992) Neuron , vol.8 , pp. 811-819
    • Ishihara, T.1    Shigemoto, R.2    Mori, K.3    Takahashi, K.4    Nagata, S.5
  • 16
    • 0033852788 scopus 로고    scopus 로고
    • Adhesion-linked kinases in cancer; emphasis on Src, focal adhesion kinase and PI 3-kinase
    • DOI 10.1016/S0959-8049(00)00153-2, PII S0959804900001532
    • Jones RJ, Brunton VG, Frame MC (2000) Adhesion-linked kinases in cancer: emphasis on Src, focal adhesion kinase and PI 3-kinase. Eur J Cancer 36:1595-1606 (Pubitemid 30616364)
    • (2000) European Journal of Cancer , vol.36 , Issue.13 , pp. 1595-1606
    • Jones, R.J.1    Brunton, V.G.2    Frame, M.C.3
  • 17
    • 0022551233 scopus 로고
    • Secretin/VIP stimulated secretion of bombesin-like peptides from human small cell lung cancer
    • Korman LY, Carney DN, Citron ML, Moody TW (1986) Secretin/VIP stimulated secretion of bombesin-like peptides from human small cell lung cancer. Cancer Res 46:1214-1218
    • (1986) Cancer Res , vol.46 , pp. 1214-1218
    • Korman, L.Y.1    Carney, D.N.2    Citron, M.L.3    Moody, T.W.4
  • 18
    • 0025649568 scopus 로고
    • Vasoactive intestinal polypeptide binds with high affinity to non-small cell lung cancer cells and elevates cAMP levels
    • Lee M, Jensen RT, Bepler G, Korman LY, Moody TW (1990) Vasoactive intestinal polypeptide binds with high affinity to non-small cell lung cancer cells and elevates cAMP levels. Peptides 11:1205-1210
    • (1990) Peptides , vol.11 , pp. 1205-1210
    • Lee, M.1    Jensen, R.T.2    Bepler, G.3    Korman, L.Y.4    Moody, T.W.5
  • 19
    • 0037088607 scopus 로고    scopus 로고
    • Activation of Trk neurotrophin receptor signaling by pituitary adenylate cyclase-activating polypeptides
    • DOI 10.1074/jbc.M107421200
    • Lee FS, Rajagopal R, Kim AH, Chang PC, Shao MV (2002) Activation of Trk neurotropin receptor signaling by pituitary adenylate cyclase-activating polypeptide. J Biol Chem 277:9096-9102 (Pubitemid 34952985)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.11 , pp. 9096-9102
    • Lee, F.S.1    Rajagopal, R.2    Kim, A.H.3    Chang, P.C.4    Chao, M.V.5
  • 21
    • 0035834881 scopus 로고    scopus 로고
    • Bombesin and gastrin releasing peptide increase tyrosine phosphorylation of focal adhesion kinase and paxillin in non-small cell lung cancer cells
    • Leyton J, Garcia L, Jensen RT, Moody TW (2001) Bombesin and gastrin releasing peptide increase tyrosine phosphorylation of focal adhesion kinase and paxillin in non-small cell lung cancer cells. Cancer Lett 162:87-95
    • (2001) Cancer Lett , vol.162 , pp. 87-95
    • Leyton, J.1    Garcia, L.2    Jensen, R.T.3    Moody, T.W.4
  • 22
    • 0037053099 scopus 로고    scopus 로고
    • Neurotensin causes tyrosine phosphorylation of focal adhesion kinase in lung cancer cells
    • DOI 10.1016/S0014-2999(02)01539-X, PII S001429990201539X
    • Leyton J, Garcia-Marin L, Jensen RT, Moody TW (2002) Neurotensin causes tyrosine phosphorylation of focal adhesion kinase in non-small cell lung cancer cells. Eur J Pharmacol 442:179-186 (Pubitemid 34626192)
    • (2002) European Journal of Pharmacology , vol.442 , Issue.3 , pp. 179-186
    • Leyton, J.1    Garcia-Marin, L.2    Jensen, R.T.3    Moody, T.W.4
  • 23
    • 0027332401 scopus 로고
    • The VIP2 receptor molecular characterization of a cDNA encoding a novel receptor for vasoactive intestinal peptide
    • Lutz EM, Sheward WJ, West KM, Morrow JA, Harmar AJ (1993) The VIP2 receptor molecular characterization of a cDNA encoding a novel receptor for vasoactive intestinal peptide. FEBS Lett 334:3-8
    • (1993) FEBS Lett , vol.334 , pp. 3-8
    • Lutz, E.M.1    Sheward, W.J.2    West, K.M.3    Morrow, J.A.4    Harmar, A.J.5
  • 25
    • 77951223899 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways
    • May V, Lutz E, MacKenzie C, Schutz K, Dozark K, Braas KM (2010) Pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways. J Biol Chem 285:9749-9761
    • (2010) J Biol Chem , vol.285 , pp. 9749-9761
    • May, V.1    Lutz, E.2    MacKenzie, C.3    Schutz, K.4    Dozark, K.5    Braas, K.M.6
  • 26
    • 84882889571 scopus 로고    scopus 로고
    • VIP and PACAP as autocrine growth factors in breast and lung cancer
    • Kastin, A. (ed), Elsevier Press
    • Moody TW, Jensen RT (2006) VIP and PACAP as autocrine growth factors in breast and lung cancer. "Handbook of Biologically active peptides," Kastin, A. (ed), Elsevier Press, 493-498
    • (2006) Handbook of Biologically Active Peptides , pp. 493-498
    • Moody, T.W.1    Jensen, R.T.2
  • 27
    • 0019812866 scopus 로고
    • High levels of intracellular bombesin characterize human small-cell lung carcinoma
    • Moody TW, Pert CB, Gazdar AF, Carney DN, Minna JD (1981) High levels of intracellular bombesin characterize human small-cell lung carcinoma. Science 214:1246-1248 (Pubitemid 12167331)
    • (1981) Science , vol.214 , Issue.4526 , pp. 1246-1248
    • Moody, T.W.1    Pert, C.B.2    Gazdar, A.F.3
  • 29
    • 0027531971 scopus 로고
    • Pituitary adenylate cyclase activating polypeptide receptors are present on small cell lung cancer cells
    • Moody TW, Zia F, Makheja A (1993b) Pituitary adenylate cyclase activating polypeptide receptors are present on small cell lung cancer cells. Peptides 14(2):241-246
    • (1993) Peptides , vol.14 , Issue.2 , pp. 241-246
    • Moody, T.W.1    Zia, F.2    Makheja, A.3
  • 31
    • 0037135257 scopus 로고    scopus 로고
    • VIP-ellipticine derivatives inhibit the growth of breast cancer cells
    • DOI 10.1016/S0024-3205(02)01741-1, PII S0024320502017411
    • Moody TW, Czerwinski G, Tarasova NI, Michejda CJ (2002a) VIP-ellipticine derivatives inhibit the growth of breast cancer cells. Life Sci 19:1005-1014 (Pubitemid 34667106)
    • (2002) Life Sciences , vol.71 , Issue.9 , pp. 1005-1014
    • Moody, T.W.1    Czerwinski, G.2    Tarasova, N.I.3    Michejda, C.J.4
  • 32
    • 0037111308 scopus 로고    scopus 로고
    • PACAP-27 tyrosine phosphorylates mitogen activated protein kinase and increases VEGF mRNAs in human lung cancer cells
    • DOI 10.1016/S0167-0115(02)00196-9, PII S0167011502001969
    • Moody TW, Leyton J, Casibang M, Pisegna J, Jensen RT (2002b) PACAP-27 tyrosine phosphorylates mitogen activated protein kinase and increases VEGF mRNAs in human lung cancer cells. Regul Pept 109:135-140 (Pubitemid 35292404)
    • (2002) Regulatory Peptides , vol.109 , Issue.1-3 , pp. 135-140
    • Moody, T.W.1    Leyton, J.2    Casibang, M.3    Pisegna, J.4    Jensen, R.T.5
  • 33
  • 34
    • 0037258822 scopus 로고    scopus 로고
    • VIP as a trophic factor in the CNS and cancer cells
    • DOI 10.1016/S0196-9781(02)00290-5
    • Moody TW, Hill JM, Jensen RT (2003b) VIP as a trophic factor in the CNS and cancer cells. Peptides 24:163-177 (Pubitemid 36165188)
    • (2003) Peptides , vol.24 , Issue.1 , pp. 163-177
    • Moody, T.W.1    Hill, J.M.2    Jensen, R.T.3
  • 35
    • 34047166458 scopus 로고    scopus 로고
    • The requirement of Ras and Rap1 for the activation of ERKs by cAMP, PACAP, and KCl in cerebellar granule cells
    • DOI 10.1111/j.1471-4159.2006.04390.x
    • Obara Y, Horgan AM, Stork PJS (2007) The requirement of Ras and Rap1 for the activation of ERKs by cAMP, PACAP and KCl in cerebellar granule cells. J Neurochem 101:470-482 (Pubitemid 46525282)
    • (2007) Journal of Neurochemistry , vol.101 , Issue.2 , pp. 470-482
    • Obara, Y.1    Horgan, A.M.2    Stork, P.J.S.3
  • 38
    • 0030035113 scopus 로고    scopus 로고
    • Cloning and characterization of the signal transduction of four splice variants of the human pituitary adenylate cyclase activating polypeptide receptor. Evidence for dual coupling to adenylate cyclase and phospholipase C
    • DOI 10.1074/jbc.271.29.17267
    • Pisegna JR, Wank SA (1996) Cloning and characterization of the signal transduction of four splice variants of the human pituitary adenylate cyclase activating polypeptide receptor. Evidence for dual coupling to adenylate cyclase and phospholipase C. J Biol Chem 271:17267-17274 (Pubitemid 26244284)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.29 , pp. 17267-17274
    • Pisegna, J.R.1    Wank, S.A.2
  • 39
    • 18144453553 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide/pituitary adenylate cyclase-activating peptide receptor subtypes in human tumors and their tissues of origin
    • Reubi JC, Laderach U, Waser B, Gebbers JD, Robberecht P, Laissue JA (2000) Vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide receptor subtypes in human tumors and their tisssues of origin. Cancer Res 60:3105-3112 (Pubitemid 30395841)
    • (2000) Cancer Research , vol.60 , Issue.11 , pp. 3105-3112
    • Reubi, J.C.1    Laderach, U.2    Waser, B.3    Gebbers, J.-O.4    Robberecht, P.5    Laissue, J.A.6
  • 41
    • 0025732695 scopus 로고
    • Neuropeptides as cellular growth-factors: Role of multiple signaling pathways
    • Rozengurt E (1991) Neuropeptides as cellular growth-factors: role of multiple signaling pathways. Eur J Clin Invest 21:123-134
    • (1991) Eur J Clin Invest , vol.21 , pp. 123-134
    • Rozengurt, E.1
  • 43
    • 0029150292 scopus 로고
    • Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains
    • Schaller MD, Otey CA, Hildebrand JD, Parsons JT (1995) Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains. J Cell Biol 130:1181-1187
    • (1995) J Cell Biol , vol.130 , pp. 1181-1187
    • Schaller, M.D.1    Otey, C.A.2    Hildebrand, J.D.3    Parsons, J.T.4
  • 44
    • 49149129916 scopus 로고    scopus 로고
    • Gene expression-based survival prediction in lung adenocarcinoma: A multi-site blinded validation study
    • Sheddon K, Taylor JM, Enkemann SA (2008) Gene expression-based survival prediction in lung adenocarcinoma: a multi-site blinded validation study. Nat Med 14:822-827
    • (2008) Nat Med , vol.14 , pp. 822-827
    • Sheddon, K.1    Taylor, J.M.2    Enkemann, S.A.3
  • 45
    • 0013020908 scopus 로고    scopus 로고
    • The origin and function of the pituitary adenylate cyclase-activating polypeptide have different tissue distributions
    • Sherwood NM, Krueckl SL, McRory JE (2000) The origin and function of the pituitary adenylate cyclase-activating polypeptide have different tissue distributions. Endocrinology 128:3055-3065
    • (2000) Endocrinology , vol.128 , pp. 3055-3065
    • Sherwood, N.M.1    Krueckl, S.L.2    McRory, J.E.3
  • 46
    • 0027240588 scopus 로고
    • Differential signal transduction by five splice variants of the PACAP receptor
    • DOI 10.1038/365170a0
    • Spengler D, Waeber C, Pantaloni C, Holsboer F, Bockaert J, Seeburg PH, Journot L (1993) Differential signal transduction by five splice variants of the PACAP receptor. Nature 365:170-175 (Pubitemid 23282064)
    • (1993) Nature , vol.365 , Issue.6442 , pp. 170-175
    • Spengler, D.1    Waeber, C.2    Pantaloni, C.3    Holsboer, F.4    Bockaert, J.5    Seeburg, P.H.6    Journot, L.7
  • 49
    • 78650409847 scopus 로고    scopus 로고
    • Paxillin predicts survival and relapse in non-small cell lung cancer by microRNA-218 targeting
    • Wu DW, Cheng YW, Wang J, Chen CY, Lee H (2010) Paxillin predicts survival and relapse in non-small cell lung cancer by microRNA-218 targeting. Cancer Res 70:10392-10401
    • (2010) Cancer Res , vol.70 , pp. 10392-10401
    • Wu, D.W.1    Cheng, Y.W.2    Wang, J.3    Chen, C.Y.4    Lee, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.