메뉴 건너뛰기




Volumn 35, Issue 8, 2012, Pages 921-928

Overnight glucose infusion suppresses renal ammoniagenesis and reduces hyperammonaemia induced by a simulated bleed in cirrhotic patients

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMMONIA; GLUCAGON; GLUCOSE; GLUTAMINE; HEMOGLOBIN; INSULIN; PLACEBO;

EID: 84858800749     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2012.05044.x     Document Type: Article
Times cited : (7)

References (50)
  • 3
    • 4544261930 scopus 로고    scopus 로고
    • Improved survival after variceal bleeding in patients with cirrhosis over the past two decades
    • Carbonell N, Pauwels A, Serfaty L, Fourdan O, Levy VG, Poupon R,. Improved survival after variceal bleeding in patients with cirrhosis over the past two decades. Hepatology 2004; 40: 652-9.
    • (2004) Hepatology , vol.40 , pp. 652-659
    • Carbonell, N.1    Pauwels, A.2    Serfaty, L.3    Fourdan, O.4    Levy, V.G.5    Poupon, R.6
  • 4
    • 0029829650 scopus 로고    scopus 로고
    • Systemic antibiotic prophylaxis after gastrointestinal hemorrhage in cirrhotic patients with a high risk of infection
    • Pauwels A, Mostefa-Kara N, Debenes B, Degoutte E, Levy VG,. Systemic antibiotic prophylaxis after gastrointestinal hemorrhage in cirrhotic patients with a high risk of infection. Hepatology 1996; 24: 802-6.
    • (1996) Hepatology , vol.24 , pp. 802-806
    • Pauwels, A.1    Mostefa-Kara, N.2    Debenes, B.3    Degoutte, E.4    Levy, V.G.5
  • 5
    • 0030879021 scopus 로고    scopus 로고
    • Treatment of hepatic encephalopathy
    • Riordan SM, Williams R,. Treatment of hepatic encephalopathy. N Engl J Med 1997; 337: 473-9.
    • (1997) N Engl J Med , vol.337 , pp. 473-479
    • Riordan, S.M.1    Williams, R.2
  • 6
    • 0037386224 scopus 로고    scopus 로고
    • Induced hyperammonemia alters neuropsychology, brain MR spectroscopy and magnetization transfer in cirrhosis
    • Balata S, Olde Damink SW, Ferguson K, et al,. Induced hyperammonemia alters neuropsychology, brain MR spectroscopy and magnetization transfer in cirrhosis. Hepatology 2003; 37: 931-9.
    • (2003) Hepatology , vol.37 , pp. 931-939
    • Balata, S.1    Olde Damink, S.W.2    Ferguson, K.3
  • 7
    • 0032993931 scopus 로고    scopus 로고
    • Upper gastrointestinal bleeding: An ammoniagenic and catabolic event due to the total absence of isoleucine in the haemoglobin molecule
    • Olde Damink SW, Dejong CH, Deutz NE, van Berlo CL, Soeters PB,. Upper gastrointestinal bleeding: an ammoniagenic and catabolic event due to the total absence of isoleucine in the haemoglobin molecule. Med Hypotheses 1999; 52: 515-9.
    • (1999) Med Hypotheses , vol.52 , pp. 515-519
    • Olde Damink, S.W.1    Dejong, C.H.2    Deutz, N.E.3    Van Berlo, C.L.4    Soeters, P.B.5
  • 8
    • 0037904292 scopus 로고    scopus 로고
    • The kidney plays a major role in the hyperammonemia seen after simulated or actual GI bleeding in patients with cirrhosis
    • Olde Damink SW, Jalan R, Deutz NE, et al,. The kidney plays a major role in the hyperammonemia seen after simulated or actual GI bleeding in patients with cirrhosis. Hepatology 2003; 37: 1277-85.
    • (2003) Hepatology , vol.37 , pp. 1277-1285
    • Olde Damink, S.W.1    Jalan, R.2    Deutz, N.E.3
  • 10
    • 0032953971 scopus 로고    scopus 로고
    • Contributions of net hepatic glycogenolysis and gluconeogenesis to glucose production in cirrhosis
    • Petersen KF, Krssak M, Navarro V, et al,. Contributions of net hepatic glycogenolysis and gluconeogenesis to glucose production in cirrhosis. Am J Physiol 1999; 276: E529-35.
    • (1999) Am J Physiol , vol.276
    • Petersen, K.F.1    Krssak, M.2    Navarro, V.3
  • 12
    • 53349142351 scopus 로고    scopus 로고
    • Regulation of hepatic glucose production and the role of gluconeogenesis in humans: Is the rate of gluconeogenesis constant?
    • Nuttall FQ, Ngo A, Gannon MC,. Regulation of hepatic glucose production and the role of gluconeogenesis in humans: is the rate of gluconeogenesis constant? Diabetes Metab Res Rev 2008; 24: 438-58.
    • (2008) Diabetes Metab Res Rev , vol.24 , pp. 438-458
    • Nuttall, F.Q.1    Ngo, A.2    Gannon, M.C.3
  • 13
    • 0014153060 scopus 로고
    • Carbohydrate metabolism of the perfused rat liver
    • Ross BD, Hems R, Freedland RA, Krebs HA,. Carbohydrate metabolism of the perfused rat liver. Biochem J 1967; 105: 869-75.
    • (1967) Biochem J , vol.105 , pp. 869-875
    • Ross, B.D.1    Hems, R.2    Freedland, R.A.3    Krebs, H.A.4
  • 14
    • 0034822681 scopus 로고    scopus 로고
    • Evidence for altered hepatic gluconeogenesis in patients with cirrhosis using in vivo 31-phosphorus magnetic resonance spectroscopy
    • Changani KK, Jalan R, Cox IJ, et al,. Evidence for altered hepatic gluconeogenesis in patients with cirrhosis using in vivo 31-phosphorus magnetic resonance spectroscopy. Gut 2001; 49: 557-64.
    • (2001) Gut , vol.49 , pp. 557-564
    • Changani, K.K.1    Jalan, R.2    Cox, I.J.3
  • 15
    • 76249133903 scopus 로고    scopus 로고
    • Role of the kidney in normal glucose homeostasis and in the hyperglycaemia of diabetes mellitus: Therapeutic implications
    • Gerich JE,. Role of the kidney in normal glucose homeostasis and in the hyperglycaemia of diabetes mellitus: therapeutic implications. Diabet Med 2010; 27: 136-42.
    • (2010) Diabet Med , vol.27 , pp. 136-142
    • Gerich, J.E.1
  • 16
    • 0021940398 scopus 로고
    • Elevated plasma ammonia level in hepatic cirrhosis: Role of glucagon
    • Kabadi UM, Eisenstein AB, Konda J,. Elevated plasma ammonia level in hepatic cirrhosis: role of glucagon. Gastroenterology 1985; 88: 750-6.
    • (1985) Gastroenterology , vol.88 , pp. 750-756
    • Kabadi, U.M.1    Eisenstein, A.B.2    Konda, J.3
  • 19
    • 0016916438 scopus 로고
    • Prediction of creatinine clearance from serum creatinine
    • Cockcroft DW, Gault MH,. Prediction of creatinine clearance from serum creatinine. Nephron Physiol 1976; 16: 31-41.
    • (1976) Nephron Physiol , vol.16 , pp. 31-41
    • Cockcroft, D.W.1    Gault, M.H.2
  • 20
    • 0032832015 scopus 로고    scopus 로고
    • Diagnostic criteria for diabetes mellitus and other categories of glucose intolerance: 1997 criteria by the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (ADA), 1998 WHO consultation criteria, and 1985 WHO criteria. World Health Organization
    • Puavilai G, Chanprasertyotin S, Sriphrapradaeng A,. Diagnostic criteria for diabetes mellitus and other categories of glucose intolerance: 1997 criteria by the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (ADA), 1998 WHO consultation criteria, and 1985 WHO criteria. World Health Organization. Diabetes Res Clin Pract 1999; 44: 21-6.
    • (1999) Diabetes Res Clin Pract , vol.44 , pp. 21-26
    • Puavilai, G.1    Chanprasertyotin, S.2    Sriphrapradaeng, A.3
  • 21
    • 9544229663 scopus 로고
    • The structure of human hemoglobin. I. The separation of the alpha and beta chains and their amino acid composition
    • Hill RJ, Konigsberg W, Guidotti G, Craig LC,. The structure of human hemoglobin. I. The separation of the alpha and beta chains and their amino acid composition. J Biol Chem 1962; 237: 1549-54.
    • (1962) J Biol Chem , vol.237 , pp. 1549-1554
    • Hill, R.J.1    Konigsberg, W.2    Guidotti, G.3    Craig, L.C.4
  • 22
    • 0037367837 scopus 로고    scopus 로고
    • Oral amino acid load mimicking hemoglobin results in reduced regional cerebral perfusion and deterioration in memory tests in patients with cirrhosis of the liver
    • Jalan R, Olde Damink SW, Lui HF, et al,. Oral amino acid load mimicking hemoglobin results in reduced regional cerebral perfusion and deterioration in memory tests in patients with cirrhosis of the liver. Metab Brain Dis 2003; 18: 37-49.
    • (2003) Metab Brain Dis , vol.18 , pp. 37-49
    • Jalan, R.1    Olde Damink, S.W.2    Lui, H.F.3
  • 23
    • 0027138879 scopus 로고
    • Renal ammonia and glutamine metabolism during liver insufficiency-induced hyperammonemia in the rat
    • Dejong CH, Deutz NE, Soeters PB,. Renal ammonia and glutamine metabolism during liver insufficiency-induced hyperammonemia in the rat. J Clin Invest 1993; 92: 2834-40.
    • (1993) J Clin Invest , vol.92 , pp. 2834-2840
    • Dejong, C.H.1    Deutz, N.E.2    Soeters, P.B.3
  • 24
    • 0026592309 scopus 로고
    • Altered glutamine metabolism in rat portal drained viscera and hindquarter during hyperammonemia
    • Dejong CH, Kampman MT, Deutz NE, Soeters PB,. Altered glutamine metabolism in rat portal drained viscera and hindquarter during hyperammonemia. Gastroenterology 1992; 102: 936-48.
    • (1992) Gastroenterology , vol.102 , pp. 936-948
    • Dejong, C.H.1    Kampman, M.T.2    Deutz, N.E.3    Soeters, P.B.4
  • 25
    • 0019408539 scopus 로고
    • Hepatic, gut, and renal substrate flux rates in patients with hepatic cirrhosis
    • Owen OE, Reichle FA, Mozzoli MA, et al,. Hepatic, gut, and renal substrate flux rates in patients with hepatic cirrhosis. J Clin Invest 1981; 68: 240-52.
    • (1981) J Clin Invest , vol.68 , pp. 240-252
    • Owen, O.E.1    Reichle, F.A.2    Mozzoli, M.A.3
  • 26
    • 0029834745 scopus 로고    scopus 로고
    • Simultaneous measurement of metabolic flux in portally-drained viscera, liver, spleen, kidney and hindquarter in the conscious pig
    • Ten Have GA, Bost MC, Suyk-Wierts JC, van den Bogaard AE, Deutz NE,. Simultaneous measurement of metabolic flux in portally-drained viscera, liver, spleen, kidney and hindquarter in the conscious pig. Lab Anim 1996; 30: 347-58.
    • (1996) Lab Anim , vol.30 , pp. 347-358
    • Ten Have, G.A.1    Bost, M.C.2    Suyk-Wierts, J.C.3    Van Den Bogaard, A.E.4    Deutz, N.E.5
  • 27
    • 0034071025 scopus 로고    scopus 로고
    • Post-feeding hyperammonaemia in patients with transjugular intrahepatic portosystemic shunt and liver cirrhosis: Role of small intestinal ammonia release and route of nutrient administration
    • Plauth M, Roske AE, Romaniuk P, Roth E, Ziebig R, Lochs H,. Post-feeding hyperammonaemia in patients with transjugular intrahepatic portosystemic shunt and liver cirrhosis: role of small intestinal ammonia release and route of nutrient administration. Gut 2000; 46: 849-55.
    • (2000) Gut , vol.46 , pp. 849-855
    • Plauth, M.1    Roske, A.E.2    Romaniuk, P.3    Roth, E.4    Ziebig, R.5    Lochs, H.6
  • 28
    • 0016405651 scopus 로고
    • Hyperglucagonemia in Laennec's cirrhosis. The role of portal-systemic shunting
    • Sherwin R, Joshi P, Hendler R, Felig P, Conn HO,. Hyperglucagonemia in Laennec's cirrhosis. The role of portal-systemic shunting. N Engl J Med 1974; 290: 239-42.
    • (1974) N Engl J Med , vol.290 , pp. 239-242
    • Sherwin, R.1    Joshi, P.2    Hendler, R.3    Felig, P.4    Conn, H.O.5
  • 29
    • 0042787673 scopus 로고    scopus 로고
    • Reduced hepatic glycogen stores in patients with liver cirrhosis
    • Krahenbuhl L, Lang C, Ludes S, et al,. Reduced hepatic glycogen stores in patients with liver cirrhosis. Liver Int 2003; 23: 101-9.
    • (2003) Liver Int , vol.23 , pp. 101-109
    • Krahenbuhl, L.1    Lang, C.2    Ludes, S.3
  • 30
    • 0021030005 scopus 로고
    • Nature and quantity of fuels consumed in patients with alcoholic cirrhosis
    • Owen OE, Trapp VE, Reichard GA Jr, et al,. Nature and quantity of fuels consumed in patients with alcoholic cirrhosis. J Clin Invest 1983; 72: 1821-32.
    • (1983) J Clin Invest , vol.72 , pp. 1821-1832
    • Owen, O.E.1    Trapp, V.E.2    Reichard Jr., G.A.3
  • 31
    • 0027154934 scopus 로고
    • Nocturnal oral glucose supplementation. The effects on protein metabolism in cirrhotic patients and in healthy controls
    • Zillikens MC, van den Berg JW, Wattimena JL, Rietveld T, Swart GR,. Nocturnal oral glucose supplementation. The effects on protein metabolism in cirrhotic patients and in healthy controls. J Hepatol 1993; 17: 377-83.
    • (1993) J Hepatol , vol.17 , pp. 377-383
    • Zillikens, M.C.1    Van Den Berg, J.W.2    Wattimena, J.L.3    Rietveld, T.4    Swart, G.R.5
  • 32
    • 0016157329 scopus 로고
    • Blood ammonia levels in advanced cirrhosis during therapeutic elevation of the insulin: Glucagon ratio
    • Walker C, Peterson W Jr, Unger R,. Blood ammonia levels in advanced cirrhosis during therapeutic elevation of the insulin: glucagon ratio. N Engl J Med 1974; 291: 168-71.
    • (1974) N Engl J Med , vol.291 , pp. 168-171
    • Walker, C.1    Peterson, Jr.W.2    Unger, R.3
  • 33
    • 0014468317 scopus 로고
    • Lack of correlation between blood glucose and ammonia concentrations
    • Conn HO, Elkington SG,. Lack of correlation between blood glucose and ammonia concentrations. Am J Med Sci 1969; 257: 132-9.
    • (1969) Am J Med Sci , vol.257 , pp. 132-139
    • Conn, H.O.1    Elkington, S.G.2
  • 34
    • 0017913167 scopus 로고
    • The effect of glucose oral administration on hyperammonemia in cirrhotics
    • Schlienger JL, Imler M,. The effect of glucose oral administration on hyperammonemia in cirrhotics. Clin Chim Acta 1978; 82: 61-7.
    • (1978) Clin Chim Acta , vol.82 , pp. 61-67
    • Schlienger, J.L.1    Imler, M.2
  • 36
    • 0015307951 scopus 로고
    • Glucose and ammonia relationships
    • Gips CH, Que GS,. Glucose and ammonia relationships. Clin Chim Acta 1972; 37: 295-7.
    • (1972) Clin Chim Acta , vol.37 , pp. 295-297
    • Gips, C.H.1    Que, G.S.2
  • 37
    • 0023226495 scopus 로고
    • The association of hepatic glycogen depletion with hyperammonemia in cirrhosis
    • Kabadi UM,. The association of hepatic glycogen depletion with hyperammonemia in cirrhosis. Hepatology 1987; 7: 821-4.
    • (1987) Hepatology , vol.7 , pp. 821-824
    • Kabadi, U.M.1
  • 38
    • 33745765238 scopus 로고    scopus 로고
    • Kidney plays a major role in ammonia homeostasis after portasystemic shunting in patients with cirrhosis
    • Olde Damink SW, Dejong CH, Deutz NE, et al., Kidney plays a major role in ammonia homeostasis after portasystemic shunting in patients with cirrhosis. Am J Physiol Gastrointest Liver Physiol 2006; 291: G189-94.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.291
    • Olde Damink, S.W.1    Dejong, C.H.2    Deutz, N.E.3
  • 40
    • 44949237199 scopus 로고    scopus 로고
    • Role of angiotensin II in the enhancement of ammonia production and secretion by the proximal tubule in metabolic acidosis
    • Nagami GT,. Role of angiotensin II in the enhancement of ammonia production and secretion by the proximal tubule in metabolic acidosis. Am J Physiol Renal Physiol 2008; 294: F874-80.
    • (2008) Am J Physiol Renal Physiol , vol.294
    • Nagami, G.T.1
  • 41
    • 0034121345 scopus 로고    scopus 로고
    • Sodium handling in patients with well compensated cirrhosis is dependent on the severity of liver disease and portal pressure
    • Jalan R, Hayes PC,. Sodium handling in patients with well compensated cirrhosis is dependent on the severity of liver disease and portal pressure. Gut 2000; 46: 527-33.
    • (2000) Gut , vol.46 , pp. 527-533
    • Jalan, R.1    Hayes, P.C.2
  • 44
    • 0026572095 scopus 로고
    • Effect of angiotensin II on ammonia production and secretion by mouse proximal tubules perfused in vitro
    • Nagami GT,. Effect of angiotensin II on ammonia production and secretion by mouse proximal tubules perfused in vitro. J Clin Invest 1992; 89: 925-31.
    • (1992) J Clin Invest , vol.89 , pp. 925-931
    • Nagami, G.T.1
  • 45
    • 0028877784 scopus 로고
    • Effect of luminal angiotensin II on ammonia production and secretion by mouse proximal tubules
    • Nagami GT,. Effect of luminal angiotensin II on ammonia production and secretion by mouse proximal tubules. Am J Physiol 1995; 269: F86-92.
    • (1995) Am J Physiol , vol.269
    • Nagami, G.T.1
  • 46
    • 0031720736 scopus 로고    scopus 로고
    • Effects of glucagon on renal and hepatic glutamine gluconeogenesis in normal postabsorptive humans
    • Stumvoll M, Meyer C, Kreider M, Perriello G, Gerich J,. Effects of glucagon on renal and hepatic glutamine gluconeogenesis in normal postabsorptive humans. Metabolism 1998; 47: 1227-32.
    • (1998) Metabolism , vol.47 , pp. 1227-1232
    • Stumvoll, M.1    Meyer, C.2    Kreider, M.3    Perriello, G.4    Gerich, J.5
  • 47
    • 3042661013 scopus 로고    scopus 로고
    • Effects of hyperglycemia, glucagon, and epinephrine on renal glucose release in the conscious dog
    • Gustavson SM, Chu C, Nishizawa M, et al., Effects of hyperglycemia, glucagon, and epinephrine on renal glucose release in the conscious dog. Metabolism 2004; 53: 933-41.
    • (2004) Metabolism , vol.53 , pp. 933-941
    • Gustavson, S.M.1    Chu, C.2    Nishizawa, M.3
  • 48
    • 0014939327 scopus 로고
    • Gluconeogenesis in the isolated perfused rat kidney
    • Bowman RH,. Gluconeogenesis in the isolated perfused rat kidney. J Biol Chem 1970; 245: 1604-12.
    • (1970) J Biol Chem , vol.245 , pp. 1604-1612
    • Bowman, R.H.1
  • 49
    • 0018243738 scopus 로고
    • Distribution along the rat nephron of three enzymes of gluconeogenesis in acidosis and starvation
    • Burch HB, Narins RG, Chu C, et al,. Distribution along the rat nephron of three enzymes of gluconeogenesis in acidosis and starvation. Am J Physiol 1978; 235: F246-53.
    • (1978) Am J Physiol , vol.235
    • Burch, H.B.1    Narins, R.G.2    Chu, C.3
  • 50
    • 0019542316 scopus 로고
    • Sites of hormone action in the mammalian nephron
    • Morel F,. Sites of hormone action in the mammalian nephron. Am J Physiol 1981; 240: F159-64.
    • (1981) Am J Physiol , vol.240
    • Morel, F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.