Fetal ethanol exposure attenuates aversive oral effects of TrpV1, but not TrpA1 agonists in rats

Experimental Biology and Medicine

Volumn 237, Issue 3, 2012, Pages 236-240

  Glendinning, John I ^a   Simons, Yael M ^a   Youngentob, Lisa ^b,c   Youngentob, Steven L ^b,c  

^a Program on US Russia Relations at Columbia s Harriman Institute   (United States)

^b State University of New York Upstate Medical University: College of Medicine   (United States)

^c Developmental Exposure Alcohol Research Center   (United States)

Author keywords

Ethanol; Fetal exposure; Oral irritation; Plasticity; Rats; TrpA1; TrpV1

Indexed keywords

ALCOHOL; ALLYL ISOTHIOCYANATE; CAPSAICIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; VANILLOID RECEPTOR 1;

ADOLESCENT; ARTICLE; AVERSIVE BEHAVIOR; BURNING SENSATION; CONTROLLED STUDY; DIET; FEMALE; LICKING; NONHUMAN; PRENATAL EXPOSURE; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; RAT; TRIGEMINAL NUCLEUS;

ALCOHOLISM; ANIMALS; CAPSAICIN; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ETHANOL; FEMALE; IRRITANTS; MUSTARD PLANT; PLANT OILS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, LONG-EVANS; TRIGEMINAL NERVE; TRPC CATION CHANNELS; TRPV CATION CHANNELS;

RATTUS;

EID: 84858763060     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1258/ebm.2011.011345     Document Type: Article

References (33)

1. Baer JS, Sampson PD, Barr HM, Connor PD, Streissguth AP. A 21-year longitudinal analysis of the effects of prenatal alcohol exposure on young adult drinking. Arch Gen Psychiatry 2003;60:377-85
2. Youngentob SL, Kent PF, Sheehe PR, Molina JC, Spear NE, Youngentob LM. Experience-induced fetal plasticity: the effect of gestational ethanol exposure on the behavioral and neurophysiologic olfactory response to ethanol odor in early postnatal and adult rats. Behav Neuorsci 2007;121:1293-305
3. Youngentob SL, Glendinning JI. Fetal ethanol exposure increases ethanol intake by making it smell and taste better. Proc Natl Acad Sci USA 2009;106:5359-64
4. Green BG. The sensitivity of the tongue to ethanol. Ann N Y Acad Sci 1987;510:315-7
5. Hellekant G. The effect of ethyl alcohol on non-gustatory receptors of the tongue of the cat. Acta Physiol Scand 1965;65:243-50
6. Simon SA, Sostman AL. Electrophysiological responses to nonelectrolytes in lingual nerve of rat and in lingual epithelia of dog. Arch Oral Biol 1991;36:805-13
7. Danilova V, Hellekant G. Oral sensation of ethanol in a primate model III: responses in the lingual branch of the trigeminal nerve of Macaca mulatta. Alcohol 2002;26:3-16
8. Trevisani M, Smart D, Gunthorpe MJ, Tognetto M, Barbieri M, Campi B, Amadesi S, Gray J, Jerman JC, Brough SJ, Owen D, Smith GD, Randall AD, Harrison S, Bianchi A, Davis JB, Geppetti P. Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1. Nature 2002;5:546-51
9. Blednov YA, Harris RA. Deletion of vanilloid receptor (TRPV1) in mice alters behavioral effects of ethanol. Neuropharmacol 2009;56:814-20
10. Bang S, Kim KY, Yoo S, Kim YG, Hwang SW. Transient receptor potential A1 mediates acetaldehyde-evoked pain sensation. Eur J Neurosci 2007;26:2516-23
11. Szeto HH. Maternal-fetal pharmacokinetics and fetal dose response relationships. Ann N Y Acad Sci 1989;562:42-55
12. Abel EL. Fetal Alcohol Syndrome and Fetal Alcohol Effects. New York: Plenum Press, 1984
13. Molina JC, Chotro MG. Association between chemosensory stimuli and cesarean delivery in rat fetuses: neonatal presentation of similar stimuli increases motor activity. Behav Neural Biol 1991;55:42-60
14. Dillon TE, Saldanha J, Giger R, Verhaagen J, Rochlin MW. Sema3A regulates the timing of target contact by cranial sensory axons. J Comp Neurol 2004;470:13-24
15. Jordt S-E, Bautista DM, Chuang H, McKenny DD, Zygmunt PM, Högestätt ED, Meng ID, Julius D. Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature 2004;427:260-265
16. Bautista DM, Jordt S-E, Nikai T, Tsuruda PR, Read AJ, Poblete J, Yamoah EN, Basbaum AI, Julius D. TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents. Cell 2006;124:1269-82
17. Ohta T, Imagawa T, Ito S. Novel agonistic action of mustard oil on recombinant and endogenous porcine transient receptor potential V1 (pTRPV1) channels. Biochem Pharmacol 2007;73:1646-56
18. Everaerts W, Gees M, Alpizar YA, Farre R, Leten C, Apetrei A, Dewachter I, van Leuven F, Vennekens R, De Ridder D, Nilius B. The capsaicin receptor TRPV1 is a crucial mediator of the noxious effects of mustard oil. Curr Biol 2011;21:316-21
19. Mori N, Kawabata F, Matsumura S, Hosokawa H, Kobayashi S, Inoue K, Fushiki T. Intragastric administration of allyl isothiocyanate increases carbohydrate oxidation via TRPV1 but not TRPA1 in mice. Am J Physiol 2011;300:R1494-505
20. Kobayashi K, Fukuoka T, Obata K, Yamanaka H, Dai Y, Tokunaga A, Noguchi K. Distinct expression of TRPM8, TRPA1, and TRPV1 mRNAs in rat primary afferent neurons with A/C-fibers and colocalization with Trk receptors. J Comp Neurol 2005;493:596-606
21. Bautista DM, Movahed P, Hinman A, Axelsson HE, Sterner O, Högestätt ED, Julius D, Jordt S-E, Zygmunt PM. Pungent products from garlic activate the sensory ion channel TRPA1. Proc Natl Acad Sci USA 2005;102:12248-52
22. Simons CT, Carstens MI, E. C. Oral irritation by mustard oil: self-desensitization and cross-desensitization with capsaicin. Chem Senses 2003;28:459-65
23. Andrade EL, Ferreira J, André E, Calixto JB. Contractile mechanisms coupled to TRPA1 receptor activation in rat urinary bladder. Biochem Pharmacol 2006;72:104-14
24. Talavera K, Gees M, Karashima Y, Meseguer VM, Vanoirbeek JAJ, Damann N, Everaerts W, Benoit M, Janssens A, Vennekens R, Viana F, Nemery B, Nilius B, Voets T. Nicotine activates the chemosensory cation channel TRPA1. Nature 2009;12:1293-300
25. Miller MW. Development of the Central Nervous System. Effects of Alcohol and Opiates. New York: Wiley-Liss, 1992
26. Spear NE, Molina JC. Fetal or infantile exposure to ethanol promotes ethanol ingestion in adolescence and adulthood. Alcohol Clin Exp Res 2005;29:909-29
27. Molina JC, Spear NE, Spear LP, Mennella JA, Lewis MJ. Alcohol and development: beyond fetal alcohol syndrome. Dev Psychobiol 2007;49:227-42
28. Glendinning JI, Gresack J, Spector AC. A high-throughput screening procedure for identifying mice with aberrant taste and oromotor function. Chem Senses 2002;27:461-74
29. Chotro MG, Arias C. Prenatal exposure to ethanol increases ethanol consumption: a conditioned response? Alcohol 2003;30:19-28
30. Bachmanov AA, Kiefer SW, Molina JC, Tordoff MG, Duffy VB, Bartoshuk LM, Mennella JA. Chemosensory factors influencing alcohol perception, preferences, and consumption. Alcohol Clin Exp Res 2003;27:220-31
31. Szallasi A, Cortright DN, Blum CA, Eid SR. The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept. Nat Rev Drug Discov 2007;6:357-72
32. Chung M-K, Lee J, Duraes G, Ro JY. Lipopolysaccharide-induced pulpitis up-regulates TRPV1 in trigeminal ganglia. J Dent Res 2011;90:1103-07
33. Zhu W, Oxford GS. Differential gene expression of neonatal and adult DRG neurons correlates with the differential sensitization of TRPV1 responses to nerve growth factor. Neurosci Lett 2011;500:192-6