Fetal ethanol exposure increases ethanol intake by making it smell and taste better

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 13, 2009, Pages 5359-5364

  Youngentob, Steven L ^a   Glendinning, John I ^b  

^a SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

^b Barnard College of Columbia University   (United States)

Author keywords

Bitter; Chemosensory plasticity; Ethanol acceptability; Gustation; Olfaction

Indexed keywords

ALCOHOL; PROTEIN P30; PROTEIN P90; QUININE;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; CONTROLLED STUDY; FEMALE; NONHUMAN; OLFACTORY DISCRIMINATION; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; RAT; TASTE ACUITY;

ALCOHOL DRINKING; ANIMALS; ETHANOL; FEMALE; FETUS; MATERNAL-FETAL EXCHANGE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; SMELL; TASTE;

CANNABIS SATIVA; NICOTIANA TABACUM; RATTUS;

EID: 65249157361     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0809804106     Document Type: Article

References (48)

1. Hannigan J, Spear L, Spear N, Goodlett C (1999) Alcohol and Alcoholism: Effects on Brain Development (Erlbaum, Mahwah, NJ).
2. Alati R, et al. (2006) In utero alcohol exposure and prediction of alcohol disorders in early adulthood: A birth cohort study. Arch Gen Psych 63:1009-1016.
3. Baer JS, Sampson PD, Barr HM, Conner PD, Streissguth AP (2003) A 21-year longitudinal analysis of the effects of prenatal alcohol exposure on young adult drinking. Arch Gen Psych 60:377-386.
4. Molina JC, Spear NE, Spear LP, Mennella JA, LewisMJ (2007) Alcohol and development: Beyond fetal alcohol syndrome. Dev Psychobiol 49:227-242.
5. Spear NE, Molina JC (2005) Fetal or infantile exposure to ethanol promotes ethanol ingestion in adolescence and adulthood. Alcoholism Clin Exp Res 29:909-929.
6. Schaal B, Orgeur P (1992) Olfaction in utero: Can the rodent model be generalized? Q J Exp Psychol B 44:245-278.
7. SchaalB, MarlierL, SoussignanR(2000) Human fetuses learn odors from their pregnant mother's diet. Chem Senses 25:729-737.
8. Faas AE, Sponton ED, Moya PR, Molina JC (2000) Differential responsiveness to alcohol odor in human neonates: Effects of maternal consumption during gestation. Alcohol 22:7-17.
9. Hill DL (2004) Neural plasticity in the gustatory system. Nutr Rev 62:S208-S217.
10. Warren RP, PfaffmanC(1959) Early experience and taste aversion. J Comp Physiol Psych 52:263-266.
11. London RM, Snowdon CT, Smithana JM (1979) Early experience with sour and bitter solutions increases subsequent ingestion. Phyiol Behav 22:1149-1155.
12. Harder DB, Maggio JC, Whitney G (1989) Assessing gustatory detection capabilities using preference procedures. Chem Senses 14:547-564.
13. Sclafani A (2006) Enhanced sucrose and polycose preference in sweet "sensitive" (C57BL/6J) and "subsensitive" (129P3/J) mice after experience with these saccharides. Phyiol Behav 87:745-756.
14. Di Lorenzo PM, Kiefer SW, Rice AG, Garcia J (1986) Neural and behavioral responsivity to ethyl alcohol as a tastant. Alcohol 3:55-61.
15. Kiefer SW, Mahadevan RS (1993) The taste of alcohol for rats as revealed by aversion generalization tests. Chem Senses 18:509-522.
16. Youngentob SL, et al. (2007) Experience-induced fetal plasticity: The effect of gestational ethanol exposure on the behavioral and neurophysiologic olfactory response to ethanol odor in early postnatal and adult rats. Behav Neurosci 121:1293-1305.
17. Youngentob SL, Molina JC, Spear NE, Youngentob LM (2007) The effect of gestational ethanol exposure on voluntary ethanol intake in early postnatal and adult rats. Behav Neurosci 121:1306-1315.
18. Eade AM, et al. (2009) Fetal ethanol-induced olfactory plasticity: The effect of adolescent ethanol re-exposure on the behavioral response to ethanol odor. Behav Brain Func 5:3.
19. Middleton FA, Carrierfenster K, Mooney SM, Youngentob SL (2009) Experienceinduced fetal plasticity: Gestational ethanol exposure alters the behavioral response to ethanol odor and the expression of neurotransmission genes in the olfactory bulb of adolescent rats. Brain Res 1252:105-116.
20. Chotro MG, Arias C (2003) Prenatal exposure to ethanol increases ethanol consumption: A conditioned response? Alcohol 30:19-28.
21. Honey PL, Galef BG, Jr (2003) Ethanol consumption by rat dams during gestation, lactation, and weaning increases ethanol consumptionby their adolescent young. Dev Psychobiol 42:252-260.
22. Bartoshuk LM, et al. (1993) PROP supertasters and the perception of ethyl alcohol. Chem Senses 18:526-527.
23. Mattes RD, DiMeglioD (2001) Ethanol perception and ingestion. Physiol Behav 72:217-229.
24. Youngentob SL (2005) A method for the rapid automated assessment of olfactory function. Chem Senses 30:219-229.
25. Youngentob SL, Mozell MM, Sheehe PR, Hornung DE (1987) A quantitative analysis of sniffing strategies in rats performing odor detection tasks. Physiol Behav 41:59-69.
26. Bachmanov AA, et al. (2003) Chemosensory factors influencing alcohol perception, preferences, and consumption. Alcoholism Clin Exp Res 27:220-231.
27. Gonzales RA, PeoC, LivdahlT, KennedyLM(2008) Experience-induced changesinsugar taste discrimination. Chem Senses 33:173-179.
28. Myers KP, SclafaniA(2006) Developmentoflearnedflavor preferences. Dev Psychobiol 48:380-388.
29. Semke E, Distel H, Hudson R (1995) Specific enhancement of olfactory receptor sensitivity associated with fetal learning of food odors in the rabbit. Naturwissenschaften 82:148-149.
30. Sullivan RM, LeonM(1986) Early olfactory learning inducesanenhanced olfactory bulb response in young rats. Brain Res 392:278-282.
31. Youngentob SL, Kent PF (1995) Enhancement of odorant-induced mucosal activity patterns in rats trained on an odorant identification task. Brain Res 670:82-88.
32. Green BG (1988) Spatial and temporal factors in the perception ofethanol irritation on the tongue. Percept Psychophys 44:108-116.
33. Zellner DA, Berridge KC, Grill HJ, Ternes JW (1985) Rats learn to like the taste of morphine. Behav Neurosci 99:290-300.
34. Moskowitz HR (1972) Subjective ideals and sensory optimization in evaluating perceptual dimensions in food. J Appl Psychol 56:60-66.
35. McBurney DH, Bartoshuk LM (1973) Interactions between stimuli with different taste qualities. Physiol Behav 10:1101-1106.
36. Laing DG, Panhuber H (1980) Olfactory sensitivity of rats reared in an odorous or deodorized environment. Physiol Behav 25:555-558.
37. Chotro MG, Kraebel KS, McKinzie DL, Molina JC Spear N (1996) Prenatal and postnatal ethanol exposure influences preweanling rats' behavioral and autonomic responding to ethanol odor. Alcohol 13:377-385.
38. Barron S, Riley EP (1992) The effects of prenatal alcohol exposure on behavioral and neuroanatomical components of olfaction. Neurotoxicol Teratol 14:291-297.
39. Youngentob SL, Schwob JE, Sheehe PR, Youngentob LM (1997) Odorant threshold following methyl bromide-induced lesions of the olfactory epithelium. Physiol Behav 62:1241-1252.
40. Slotnick B, Bodyak N (2002) Odor discrimination and odor quality perception in rats with disruption of connections between the olfactory epithelium and olfactory bulbs. J Neurosci 22:4205-4216.
41. Mooney SM, Miller MW (2007) Time-specific effects of ethanol exposure on cranial nerve nuclei: Gastrulation and neuronogenesis. Exp Neurol 205:56-63.
42. Trevisani M, et al. (2002) Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1. Nat Neurosci 5:546-551.
43. Ellingson JM, Silbaugh BC, Brasser SM (2009) Reduced oral ethanol avoidance in mice lacking transient receptor potential channel vanilloid receptor 1. Behav Genet 39:62-72.
44. Prescott J, Swain-Campbell N (2000) Responses to repeated oral irritation by capsaicin, cinnamaldehyde, and ethanol in PROP tasters and nontasters. Chem Senses 25:239-246.
45. Gesteland RC, Yancey RA, Farbman AI (1982) Development of olfactory receptor neuron selectivity in the rat fetus. Neuroscience 7:3127-3136.
46. Farbman AI (1991) in Smell and Taste in Health and Disease, ed Getchell TV (Raven, New York), pp 19-33.
47. Spector AC, Grill HJ, Norgren R (1993) Concentration-dependent lickingof sucrose and sodium chloride in rats with parabrachial gustatory lesions. Physiol Behav 53:277-283.
48. Glendinning JI, Gresack J, Spector AC (2002) A high-throughput screening procedure for identifying mice with aberrant taste and oromotor function. Chem Senses 27:461-474.