Oral irritation by mustard oil: Self-desensitization and cross-desensitization with capsaicin

Chemical Senses

Volumn 28, Issue 6, 2003, Pages 459-465

  Simons, Christopher T ^a   Carstens, Mirela Iodi ^a   Carstens, E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Mustard oil (allyl isothiocyanate); Oral irritation; Psychophysics; Tongue; Trigeminal chemoreception

Indexed keywords

ALLYL ISOTHIOCYANATE; CAPSAICIN; IRRITANT AGENT; PLANT EXTRACT; VEGETABLE OIL;

ADULT; ARTICLE; CHEMOSENSITIVITY; CONTROLLED STUDY; DESENSITIZATION; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; MOUTH MUCOSA; MUCOSA INFLAMMATION; NOCICEPTIVE STIMULATION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SENSITIZATION; SENSORY STIMULATION; SEQUENTIAL ANALYSIS; STATISTICAL SIGNIFICANCE; STIMULUS RESPONSE; TONGUE; TOXICITY TESTING; BRASSICA; DRUG ANTAGONISM; DRUG EFFECT; DRUG TOLERANCE; MIDDLE AGED; ORAL DRUG ADMINISTRATION; PSYCHOPHYSICS;

HIATUS;

ADMINISTRATION, ORAL; ADULT; CAPSAICIN; DRUG TOLERANCE; FEMALE; HUMANS; IRRITANTS; MALE; MIDDLE AGED; MUSTARD PLANT; PLANT EXTRACTS; PLANT OILS; PSYCHOPHYSICS; TONGUE;

EID: 1642572082     PISSN: 0379864X     EISSN: None     Source Type: Journal    
DOI: 10.1093/chemse/28.6.459     Document Type: Article

References (47)

1. Affeltranger, M.A., McBurney, D.H. and Balaban, C.D. (2002) Interaction of burn between capsaicin, piperine and zingerone. Chem. Senses, 27, A25.
2. Balaban, C.D., McBurney, D.H. and Stoulis, M. (1999) Time course of burn to repeated applications of capsaicin. Physiol. Behav., 66, 109-112.
3. Bereiter, D.A. and Benetti, A.P. (1996) Excitatory amino release within spinal trigeminal nucleus after mustard oil injection into the temporomandibular joint region of the rat. Pain, 67, 451-459.
4. Bi, J., Ennis, D.M. and O'Mahony, M. (1995) How to estimate and use the variance of d' from difference tests. J. Sens. Stud., 12, 87-104.
5. Brand, G. and Jacquot, L. (2002) Sensitization and desensitization to all isothiocyanate (mustard oil) in the nasal cavity. Chem. Senses, 27, 593-598.
6. Carstens, E., Iodi Carstens, M., Dessirier, J.M., O'Mahony, M., Simons, C.T., Sudo, M. and Sudo S. (2002) It hurts so good: oral irritation by spices and carbonated drinks and the underlying neural mechanisms. Food Qual. Pref., 13, 431-443.
7. Caterina, M.J., Schumacher, M.A., Tominaga, M., Rosen, T.A., Levine, J.D. and Julius, D. (1997) The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature, 389, 816-824.
8. Cliff, M.A. and Green, B.G. (1994) Sensory irritation and coolness produced by menthol: evidence for selective desensitization of irritation. Physiol. Behav, 56, 1021-1029.
9. Dessirier, J.M., O'Mahony, M. and Carstens, E. (1997) Oral irritant effects of nicotine: psychophysical evidence for decreased sensation following repeated application and lack of cross-desensitization to capsaicin. Chem. Senses, 22, 483-492.
10. Dessirier, J.M., Nguyen, N., Sieffermann, J.M., Carstens, E. and O'Mahony, M. (1999) Oral irritant properties of piperine and nicotine: psychophysical evidence for asymmetrical desensitization effects. Chem Senses, 24, 405-413.
11. Dessirier, J.M., O'Mahony, M., Iodi-Carstens, M. and Carstens, E. (2000a) Sensory properties of citric acid: psychophysical evidence for sensitization, self-desensitization, cross-desensitization and cross-stimulus-induced recovery following capsaicin. Chem. Senses, 25, 769-780.
12. Dessirier, J.M., Simons, C.T., Carstens, M.I., O'Mahony, M. and Carstens, E. (2000b) Psychophysical and neurobiological evidence that the oral sensation elicited by carbonated water is of chemogenic origin. Chem. Senses, 25, 277-284.
13. Dessirier, J.M., O'Mahony, M. and Carstens, E. (2001a) Oral irritant properties of menthol: sensitizing and desensitizing effects of repeated application and cross-desensitization to nicotine. Physiol. Behav., 73, 25-36.
14. Dessirier, J.M., O'Mahony, M., Iodi-Carstens, M., Yao, E. and Carstens, E. (2001b) Oral irritation by sodium chloride: sensitization, self-desensitization, and cross-sensitization to capsaicin. Physiol. Behav., 72, 317-324.
15. Docherty, R.J., Yeats, J.C., Bevan, S. and Boddeke, H.W. (1996) Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats. Pflugers Arch., 431, 828-837.
16. Dux, M., Jancso, G., Sann, H. and Pierau, F.K. (1996) Inhibition of the neurogenic inflammatory response by lidocaine in rat skin. Inflamm. Res. 1996, 45, 10-13.
17. Ennis, D.M. (1993) The power of sensory discrimination methods. J. Sens. Stud. 8, 353-370.
18. Fiorentino, P.M., Cairns, B.E. and Hu, J.W. (1999) Development of inflammation after application of mustard oil or glutamate to the rat temporomandibular joint. Arch. Oral Biol., 44, 27-32.
19. Green, B.G. (1989) Capsaicin sensitization and desensitization on the tongue produced by brief exposures to a low concentration. Neurosci. Lett., 107, 173-178.
20. Green, B.G. (1991) Capsaicin cross-desensitization on the tongue: psycophysical evidence that oral chemical irritation is mediated by more than one sensory pathway. Chem. Senses, 16, 675-689.
21. Green, B.G. (1996) Rapid recovery from capsaicin desensitization during recurrent stimulation. Pain, 68, 245-253.
22. Green, B.G. and Rentmeister-Bryant, H. (1998) Temporal characteristics of capsaicin desensitization and stimulus-induced recovery in the oral cavity. Physiol. Behav., 65, 141-149.
23. Handwerker, H.O., Anton, F., Kocher, L. and Reeh, P.W. (1987) Nociceptor functions in intact skin and in neurogenic or non-neurogenic inflammation. Acta Physiol. Hung., 69, 333-342.
24. Handwerker, H.O., Forster, C. and Kirchhoff, C. (1991) Discharge patterns of human C-fibers induced by itching and burning stimuli. J. Neurophysiol., 66, 307-315.
25. Haas, D.A., Nakanishi, O., MacMillan, R.E., Jordan, R.C., and Hu, J.W. (1992) Development of an orofacial model of acute inflammation in the rat. Arch. Oral Biol., 37, 417-422.
26. Inoue, H., Asaka, T., Nagata, N. and Koshihara, Y. (1997) Mechanism of mustard oil-induced skin inflammation in mice. Eur. J. Pharmacol., 333, 231-240.
27. Kim, K.-O. and O'Mahony, M. (1998) A new approach to category scales of intensity I. Traditional versus rank-rating. J. Sens. Stud., 13, 241-249.
28. Koltzenburg, G. Lundberg, L.E.R., and Torebjörk, H.E. (1992) Dynamic and static components of mechniacal hyperalgesia in human hairy skin. Pain, 51, 207-219.
29. Kress, M. and Reeh, P.W. (1996) Transduction mechanisms in nociceptors - Chemical excitation and sensitization in nociceptors. In Cervero, F., Belmonte, C. (eds) Neurobiology of Nociceptors. Oxford University Press, Oxford, pp. 258-297.
30. LaMotte, R.H., Thalhammer, J.G. and Torebjörk, H.E. (1982) Peripheral neuronal mechanisms of cutaneous hyperalgesia following mild injury by heat. J. Neurosci., 2, 756-781.
31. Liu, L. and Simon, S.A. (1996a) Similarities and differences in the currents activated by capsaicin, piperine, and zingerone in rat trigeminal ganglion cells. J. Neurophysiol., 76, 1858-1869.
32. 2+ dependence in rat trigeminal ganglion cells. J. Neurophysiol., 75, 1503-1514.
33. Liu, L., Oortgiesen, M., Li, L. and Simon, S.A. (2001) Capsaicin inhibits activation of voltage-gated sodium currents in capsaicin-sensitive trigeminal ganglion neurons. J. Neurophysiol., 85, 745-758.
34. Lippe, I.T., Stabentheiner, A. and Holzer, P. (1993a) Participation of nitric oxide in the mustard oil-induced neurogenic inflammation of the rat paw skin. Eur J. Pharmacol., 232, 113-120.
35. Lippe, I.T., Stabentheiner, A. and Holzer, P. (1993b) Role of nitric oxide in the vasodilator but not exudative component of mustard oil-induced inflammation in rat skin. Agents Actions, 38, C22-C24.
36. Margerl, W., Gramer, G. and Handwerker, H.O. (1990) Sensations and local inflammatory responses induced by application of carbachol, dopamine, 5-HT histamine and mustard oil to the skin of humans. Pflugers Arch. 415, 107.
37. McBurney, D.H., Balaban, C.D., Christopher, D.E. and Harvey, C. (1997) Adaptation to capsaicin within and across days. Physiol. Behav., 61, 181-190.
38. McBurney, D.H., Balaban, C.D., Popp, J.R. and Rosenkranz, J.E. (2001) Adaptation to capsaicin burn: effects of concentration and individual differences. Physiol. Behav., 72, 205-216.
39. McKemy, D.D., Neuhausser, W.M. and Julius, D. (2002) Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature, 416, 52-58.
40. Piper, A.S., Yeats, J.C., Bevan, S. and Docherty, R.J. (1999) A study of the voltage dependence of capsaicin-activated membrane currents in rat sensory neurones before and after acute desensitization, J. Physiol., 518, 721-733.
41. Prescott, J. and Stevenson, R.J. (1996) Desensitization to oral zingerone irritation: effects of stimulus parameters. Physiol. Behav, 60, 1473-1480.
42. Prescott, J. (1999) The generalizability of capsaicin sensitization and desensitization. Physiol. Behav., 66, 741-749.
43. Stevens, D.A. and Lawless, H.T. (1987) Enhancement of responses to sequential presentation of oral chemical irritants. Physiol. Behav., 39, 63-65.
44. Su, X., Wachtel, R.E. and Gebhart, G.F (1999) Capsaicin sensitivity and voltage-gated sodium currents in colon sensory neurons from rat dorsal root ganglia. Am. J. Physiol., 277, G1180-G1188.
45. Torebjörk, H.E., Lundeburg, L.E. and LaMotte, R.H. (1992) Central changes in processing of mechnoreceptive input in capsaicin-induced secondary hyperalgesia in humans. J. Physiol., 448, 765-780.
46. Treede, R.D., Meyer, R.A., Raja, S.N. and Campbell, J.N. (1995) Evidence ffor two different heat transduction mechanisms in nociceptive afferents innervating monkey skin. J. Physiol., 483, 747-758.
47. Yu, X.M., Sessle, B.J., Haas, D.A., Izzo, A., Vernon, H. and Hu, J.W. (1996) Involvement of NMDA receptor mechanisms in jaw electromyographic activity and plasma extravasation induced by inflammatory irritant application to temporomandibular joint region of rats. Pain, 68, 169-178.