Secreted phospholipase A 2 group IIA is a neurotoxin released by stimulated human glial cells

Molecular and Cellular Neuroscience

Volumn 49, Issue 4, 2012, Pages 430-438

  Villanueva, Erika B ^a   Little, Jonathan P ^a   Lambeau, Gérard ^b   Klegeris, Andis ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Alzheimer's disease; Astrocytes; Microglia; Neurodegeneration; Neuroinflammation; Neuroprotection

Indexed keywords

MESSENGER RNA; NEUROTOXIN; SECRETED PHOSPHOLIPASE A2 GROUP IIA; UNCLASSIFIED DRUG;

ARTICLE; ASTROCYTE; CELL STIMULATION; CYTOTOXICITY; DEGENERATIVE DISEASE; ENZYME ACTIVITY; ENZYME RELEASE; GLIA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MONOCYTE MACROPHAGE PRECURSOR CELL; NERVOUS SYSTEM INFLAMMATION; NEUROBLASTOMA CELL; NEUROPROTECTION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SUPERNATANT;

CELL SURVIVAL; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; GROUP II PHOSPHOLIPASES A2; HUMANS; INFLAMMATION; NEUROGLIA; NEURONS; NEUROTOXINS; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84858717087     PISSN: 10447431     EISSN: 10959327     Source Type: Journal    
DOI: 10.1016/j.mcn.2012.02.006     Document Type: Article

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