Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2

Journal of Medicinal Chemistry

Volumn 51, Issue 15, 2008, Pages 4708-4714

  Oslund, Rob C ^a   Cermak, Nathan ^a   Gelb, Michael H ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (1 BENZYL 4 METHOXY 1H 6,7 BENZOINDOL 2 YL) ETHANOL; 1 BENZYL 2 ACETYL 4 METHOXY 6,7 BENZOINDOLE; 1 BENZYL 2 CARBOMETHOXY 4 METHOXY 6,7 BENZOINDOLE; 1 BENZYL 2 CARBOXYLIC ACID 4 MTHOXY 6,7 BENZOINDOLE; 1 BENZYL 2 ETHYL 4 METHOXY 1H 6,7 BENZOINDOLE; 2 (3 (2 AMINO 2 OXOACETYL) 1 BENZYL 2 ETHYL 1H 6,7 BENZOINDOL 4 YLOXY)ACETIC ACID; METHYL 2 (1 BENZYL 2 ETHYL 1H 6,7 BENZOINDOL 4 YLOXY)ACETATE; METHYL 2 (3 (2 AMINO 2 OXOACETYL) 1 BENZYL 2 ETHYL 1H 6,7 BENZOINDOL 4 YLOXY)ACETATE; PHOSPHOLIPASE A2 INHIBITOR; UNCLASSIFIED DRUG; VARESPLADIB;

ARTICLE; CRYSTAL STRUCTURE; DRUG POTENCY; MOUSE; NONHUMAN;

ANIMALS; ENZYME INHIBITORS; HUMANS; INDOLES; INDOLIZIDINES; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PHOSPHOLIPASES A2, SECRETORY; SENSITIVITY AND SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 49449096539     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm800422v     Document Type: Article

References (25)

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