No effect of protein coingestion on exogenous glucose oxidation during exercise

Medicine and Science in Sports and Exercise

Volumn 44, Issue 4, 2012, Pages 701-708

  Rowlands, David Stephen ^a   Wadsworth, Daniel P ^a  

^a MASSEY UNIVERSITY   (New Zealand)

Author keywords

endurance exercise; glucose oxidation; gut comfort; Stable isotope

Indexed keywords

GLUCOSE; LACTIC ACID;

ADULT; ARTICLE; ATHLETIC PERFORMANCE; BICYCLE; BLOOD; CARBOHYDRATE DIET; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; ENDURANCE; GLUCOSE BLOOD LEVEL; HUMAN; MALE; METABOLISM; OXYGEN CONSUMPTION; PHYSIOLOGY; PROTEIN INTAKE; PSYCHOLOGICAL ASPECT; RANDOMIZED CONTROLLED TRIAL;

ADULT; ATHLETIC PERFORMANCE; BICYCLING; BLOOD GLUCOSE; CROSS-OVER STUDIES; DIETARY CARBOHYDRATES; DIETARY PROTEINS; GLUCOSE; HUMANS; LACTIC ACID; MALE; OXYGEN CONSUMPTION; PHYSICAL ENDURANCE;

EID: 84858700309     PISSN: 01959131     EISSN: 15300315     Source Type: Journal    
DOI: 10.1249/MSS.0b013e318237e7c5     Document Type: Article

References (38)

1. Betts JA, Williams C, Boobis L, Tsintzas K. Increased carbohydrate oxidation after ingesting carbohydrate with added protein. Med Sci Sports Exerc. 2008;40(5):903-12.
2. Blomstrand E, Ek S, Newsholme EA. Influence of ingesting a solution of branched-chain amino acids on plasma and muscle concentrations of amino acids during prolonged submaximal exercise. Nutrition. 1996;12(7-8):485-90. (Pubitemid 26299986)
3. Blomstrand E, Eliasson J, Karlsson HKR, Kohnke R. Branchedchain amino acids activate key enzymes in protein synthesis after physical exercise. J Nutr. 2006;136(1):269-73S.
4. Blomstrand E, Hassme?n P, Ekblom B, Newsholme E. Administration of branched-chain amino acids during sustained exercise-effects on performance and on plasma concentration of some amino acids. Eur J Appl Physiol. 1991;63(2):83-8.
5. Boirie Y, Dangin M, Gachon P, Vasson MP, Maubois JL, Beaufrère B. Slow and fast dietary proteins differently modulate postprandial protein accretion. Proc Nat Acad Sci USA. 1997; 94(26):14930-5. (Pubitemid 28041477)
6. Breen L, Tipton KD, Jeukendrup AE. No effect of carbohydrateprotein on cycling performance and indices of recovery. Med Sci Sports Exerc. 2010;42(6):1140-8.
7. Brouns F, Kovacs E. Functional drinks for athletes. Trends Food Sci Technol. 1997;8(12):414-21. (Pubitemid 28051986)
8. Coeffier M, Hecketsweiler B, Hecketsweiler P, Dechelotte P. Effect of glutamine on water and sodium absorption in human jejunum at baseline and during PGE1-induced secretion. J Appl Physiol. 2005;98(6):2163-8. (Pubitemid 40726911)
9. Craig H. Isotopic standards for carbon and oxygen and correction factors. Geochem Cosmochim Acta. 1957;12:133-49.
10. Ferguson-Stegall L, McCleave EL, Ding Z, et al. The effect of a low carbohydrate beverage with added protein on cycling endurance performance in trained athletes. J Str Cond Res. 2010;24(10): 2577-86.
11. Hopkins WG, Marshall SW, Batterham AM, Hanin J. Progressive statistics for studies in sports medicine and exercise science. Med Sci Sports Exerc. 2009;41(1):3-13.
12. Ivy JL, Res PT, Sprauge RC,Widzer MO. Effect of a carbohydrate-protein supplement on endurance performance during exercise of varying intensity. Int J Sport Nutr Exerc Metabol. 2003;13:382-95. (Pubitemid 37108369)
13. Jeukendrup A, Wallis G. Measurement of substrate oxidation during exercise by means of gas exchange measurements. Int J Sports Med. 2005;26(1 suppl):S1-10.
14. Jeukendrup AE. Carbohydrate intake during exercise and performance. Nutrition. 2004;20(7-8):669-77. (Pubitemid 38798084)
15. Koopman R, Wagenmakers AJM, Manders RJF, et al. Combined ingestion of protein and free leucine with carbohydrate increases postexercise muscle protein synthesis in vivo in male subjects. Am J Physiol Endocrinol Metabol. 2005;288(4):E645-53. (Pubitemid 40397198)
16. Leiper JB. Intestinal water absorption-implications for the formulation of rehydration solutions. Int J Sports Med. 1998;19:S129-32.
17. Lillioja S, Bogardus C, Mott DM, Kennedy AL, Knowler WC, Howard BV. Relationship between insulin-mediated glucose disposal and lipid metabolism in man. J Clin Invest. 1985;75:1106-15. (Pubitemid 15087134)
18. Martínez-Lagunas V, Ding Z, Bernard JR, Wang B, Ivy JL. Added protein maintains efficacy of a low-carbohydrate sports drink. J Str Cond Res. 2010;24(1):48-59.
19. Mittleman KD, Ricci MR, Bailey SP. Branched-chain amino acids prolong exercise during heat stress in men and women. Med Sci Sports Exerc. 1998;30(1):83-91. (Pubitemid 28071387)
20. Murray R, Bartoli W, Stofan J, Horn M, Eddy D. A comparison of the gastric emptying characteristics of selected sports drinks. Int J Sport Nutr Exerc Metabol. 1999;9(3):263-74. (Pubitemid 29440100)
21. O'Brien WJ, Rowlands DS. Fructose-maltodextrin ratio in a carbohydrate-electrolyte solution differentially affects exogenous carbohydrate oxidation rate, gut comfort, and performance. Am J Physiol Gastro Liver Physiol. 2011;300(1):G181-9.
22. Osterberg KL, Zachwieja JJ, Smith JW. Carbohydrate and carbohydrate+ protein for cycling time-trial performance. J Sports Sci. 2008;26(3):227-33. (Pubitemid 350302167)
23. Pallikarakis N, Sphiris N, Lefebvre P. Influence of the bicarbonate pool of the occurrence of 13CO2 in exhaled air. Eur J Appl Physiol. 1991;63:179-83.
24. Robert JJ, Koziet J, Chauvet D, Darmaun D, Desjeux JF, Young VR. Use of 13C labelled glucose for estimating glucose oxidation: some design considerations. J Appl Physiol. 1987;63:1725-32. (Pubitemid 18016390)
25. Rowlands DS, Rössler K, Thorp RM, et al. Effect of dietary protein content during recovery from high-intensity cycling on subsequent performance and markers of stress, inflammation, and muscle damage in well-trained men. Appl Physiol Nutr Metab. 2008;33:39-51.
26. Rowlands DS, Thorburn MS, Thorp RM, Rossi A, Clarke J. Can the addition of L-arginine or L-glutamine to exercise energy-hydration beverages facilitate glucose and fluid delivery? Physiologist. 2008; 51(6):56 No. 22.3.
27. Saunders MJ, Kane MD, Todd MK. Effects of a carbohydrateprotein beverage on cycling endurance and muscle damage. Med Sci Sports Exerc. 2004;36(7):1233-8. (Pubitemid 38879001)
28. Saunders MJ, Luden ND, Todd MK. Postexercise carbohydrate-protein- antioxidant ingestion decreases plasma creatine kinase and muscle soreness. Int J Sport Nutr Exerc Metabol. 2007;17: 109-23. (Pubitemid 47124237)
29. Saunders MJ, Moore RW, Kies AK, Luden ND, Pratt CA. Carbohydrate and protein hydrolysate coingestion's improvement of late-exercise time-trial performance. Int J Sport Nutr Exerc Metabol. 2009;19(2):136-49.
30. Smith JW, Zachwieja JJ, Peronnet F, et al. Fuel selection and cycling endurance performance with ingestion of [13C]glucose: evidence for a carbohydrate dose response. J Appl Physiol. 2010; 108(6):1520-9.
31. Spiller GA, Jenson CD, Patterson TS, Chuck CS, Whittam JH, Scala J. Effect of protein dose on serum glucose and insulin response to sugars. Am J Clin Nutr. 1987;46:474-80. (Pubitemid 18003385)
32. Stearns RL, Emmanuel H, Volek JS, Casa DJ. Effects of ingesting protein in combination with carbohydrate during exercise on endurance performance: a systematic review with meta-analysis. J Strength Cond Res. 2010;24(8):2192-202.
33. Thorburn MS, Vistisen B, Thorp RM, et al. Attenuated gastric tolerance but no benefit to performance with adaptation to octanoaterich esterified oils in well-trained male cyclists. J Appl Physiol. 2006; 1001:1733-43. (Pubitemid 44904496)
34. Toone RJ, Betts JA. Isocaloric carbohydrate versus carbohydrate-protein ingestion and cycling time-trial performance. Int J Sport Nutr Exerc Metabol. 2010;20(1):34-43.
35. Valentine RJ, Saunders MJ, Todd MK, St Laurent T. Influence of carbohydrate-protein beverage on cycling endurance and indices of muscle disruption. Int J Sport Nutr Exerc Metab. 2008;18(4):363-78.
36. Van Essen M, Gibala MJ. Failure of protein to improve time trial performance when added to a sports drink. Med Sci Sports Exerc. 2006;38(8):1476-83. (Pubitemid 44215757)
37. van Hall G, Raaymakers JSH, Saris WHM, Wagenmakers AJM. Ingestion of branched-chain amino acids and tryptophan during sustained exercise in man: failure to affect performance. J Physiol. 1995;486:789-94.
38. Wapnir R, Wingertzahn M, Teichberg S. L-Arginine in low concentration improves rat intestinal water and sodium absorption from oral rehydration solutions. Gut. 1997;40(5):602-7. (Pubitemid 27278326)