Effect of glutamine on water and sodium absorption in human jejunum at baseline and during PGE1-induced secretion

Journal of Applied Physiology

Volumn 98, Issue 6, 2005, Pages 2163-2168

  Coëffier, Moïse ^a   Hecketsweiler, Bernadette ^a   Hecketsweiler, Philippe ^a   Déchelotte, Pierre ^a  

^a Faculté de Médecine Pharmacie   (France)

Author keywords

Amino acids; Oral rehydration solution; Prostaglandins; Secretory diarrhea

Indexed keywords

ALANINE; BIOCHEMICAL MARKER; GLUCOSE; GLUTAMINE; MACROGOL 4000; MANNITOL; ORAL REHYDRATION SOLUTION; PROSTAGLANDIN E1; SODIUM; SODIUM CHLORIDE; WATER;

ADULT; ARTICLE; DIARRHEA; DISEASE SIMULATION; EVALUATION; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; NUTRITIONAL SUPPORT; ORAL REHYDRATION THERAPY; PRIORITY JOURNAL; SECRETORY DIARRHEA; SMALL INTESTINE ABSORPTION; SODIUM ABSORPTION; STEADY STATE; TUBE; WATER ABSORPTION;

ADSORPTION; ADULT; ALANINE; ALPROSTADIL; BASAL METABOLISM; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLUCOSE; GLUTAMINE; HUMANS; JEJUNUM; MALE; SODIUM; WATER;

EID: 19444381100     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00761.2004     Document Type: Article

References (42)

1. Abely M, Dallet P, Boisset M, and Desjeux JF. Effect of cholera toxin on glutamine metabolism and transport in rabbit ileum. Am J Physiol Gastrointest Liver Physiol 278: G789-G796, 2000.
2. Argenzio RA, Rhoads JM, Armstrong M, and Gomez G. Glutamine stimulates prostaglandin-sensitive Na(+)-H+ exchange in experimental porcine cryptosporidiosis. Gastroenterology 106: 1418-1428, 1994.
3. Armstrong WA. Cellular mechanisms of ion transport in the small intestine. In: Physiology of the Gastrointestinal Tract, edited by Johnson LR. New York: Raven, 1987, p. 1251-1265.
4. Banwell JG, Pierce NF, Mitra RC, Birgham K, Caranasos G, and Keimowitz R. Intestinal fluid and electrolyte transport in human cholera. J Clin Invest 49: 183-195, 1970.
5. Blikslager A, Hunt E, Guerrant R, Rhoads M, and Argenzio R. Glutamine transporter in crypts compensates for loss of villus absorption in bovine cryptosporidiosis. Am J Physiol Gastrointest Liver Physiol 281: G645-G653, 2001.
6. Bradford NM and McGivan JD. The transport of alanine and glutamine into isolated rat intestinal epithelial cells. Biochim Biophys Acta 689: 55-62, 1982.
7. Carneiro-Filho BA, Bushen OY, Brito GA, Lima A, and Guerrant R. Glutamine analogues as adjunctive therapy for infectious diarrhea. Curr Infect Dis Rep 5: 114-119, 2003.
8. Carpenter CC, Sack RB, Feeley JC, and Steenberg R. Site and characteristics of electrolyte loss and effect of intraluminal glucose in experimental canine cholera. J Clin Invest 47: 1210-1220, 1968.
9. Coëffier M, Claeyssens S, Hecketsweiler B, Lavoinne A, Ducrotté P, and Déchelotte P. Enteral non-essential amino acids stimulate protein synthesis and glutamine decreases ubiquitin mRNA level in human duodenal mucosa. Am J Physiol Gastrointest Liver Physiol 285: G266-G273, 2003.
10. Cole J, Blikslager A, Hunt E, Gookin J, and Argenzio R. Cyclooxygenase blockade and exogenous glutamine enhance sodium absorption in infected bovine ileum. Am J Physiol Gastrointest Liver Physiol 284: G516-G524, 2003.
11. Daniel H. Molecular and integrative physiology of intestinal peptide transport. Annu Rev Physiol 66: 361-384, 2004.
12. Déchelotte P, Darmaun D, Rongier M, Hecketsweiler B, Rigal O, and Desjeux JF. Absorption and metabolic effects of enterally administered glutamine in humans. Am J Physiol Gastrointest Liver Physiol 260: G677-G682, 1991.
13. Déchelotte P, Darmaun D, Rongier M, and Desjeux JF. Glutamine transport in isolated rabbit ileal epithelium. Gastroenterol Clin Biol 13: 816-821, 1989.
14. Fordtran JS. Stimulation of active and passive sodium absorption by sugars in the human jejunum. J Clin Invest 55: 728-737, 1975.
15. Hellier MD, Thirumalai C, and Holdsworth CD. The effect of amino acids and dipeptides on sodium and water absorption in man. Gut 14: 41-45, 1973.
16. Hunt JB, Thillainayagam AV, Carnaby S, Fairclough P, Clark M, and Farthing MJG. Absorption of a hypotonic oral rehydration solution in a human model of cholera. Gut 35: 211-214, 1994.
17. Hunt JB, Thillainayagam AV, Salim A, Carnaby S, Elliott EJ, and Farthing MJG. Water and solute absorption from a new hypotonic oral rehydration solution: evaluation in human and animal models. Gut 33: 1652-1659, 1992.
18. Hyden SA. A turbidimetric method for the determination of higher polyethylene glycols in biological materials. K Lantbr-Hogsk Annlr 22: 139-145, 1956.
19. Islam S, Mahalanabis D, Chowdhury AK, Wahed M, and Rahman AS. Glutamine is superior to glucose in stimulating water and electrolyte absorption across rabbit ileum. Dig Dis Sci 42: 420-423, 1997.
20. Kaunitz JD, Gunther R, and Wright EM. Involvement of multiple sodium ions in intestinal D-glucose transport. Proc Natl Acad Sci USA 79: 2315-2318, 1982.
21. 14C-L-glycine) absorption during cholera. Am J Gastroenterol 81: 536-539, 1986.
22. Krejs G, Fordtran J, Fahrenkrug J, Schaffalitzky de Muckadell O, Fischer J, Humphrey C, O'Dorisio T, Said S, Walch JH, and Shulkes AA. Effect of VIP infusion on water and ion transport in the human jejunum. Gastroenterology 78: 722-727, 1980.
23. Levine SA, Nath SK, Tse CM, Yun C, and Donowitz M. L-Glutamine in intestinal sodium absorption: lessons for physiology, pathobiology, and therapy for diarrhea. Gastroenterology 106: 1698-1702, 1994.
24. Lima AA, Carvalho GH, Figueiredo AA, Gifoni A, Soares A, Silva E, and Guerrant R. Effects of an alanyl-glutamine-based oral rehydration and nutrition therapy solution on electrolyte and water absorption in a rat model of secretory diarrhea induced by cholera toxin. Nutrition 18: 458-462, 2002.
25. Mahalanabis D. Current status of oral rehydration as a strategy for the control of diarrhoeal diseases. Indian J Med Res 104: 115-124, 1996.
26. Matuchansky C and Bernier JJ. Effect of prostaglandin E 1 on glucose, water, and electrolyte absorption in the human jejunum. Gastroenterology 64: 1111-1118, 1973.
27. Modigliani R, Rambaud JC, and Bernier JJ. The method of intraluminal perfusion of the human small intestine. II. Absorption studies in health. Digestion 9: 264-290, 1973.
28. Nalin DR, Cash RA, Rahman M, and Yunus M. Effect of glycine and glucose on sodium and water adsorption in patients with cholera. Gut 11: 768-772, 1970.
29. 14C]glutamine fluxes across rabbit ileum in experimental bacterial diarrhea. Am J Physiol Gastrointest Liver Physiol 262: G312-G318, 1992.
30. +-glucose cotransport in an epithelial secretory cell line sensitive to cholera toxin. Am J Physiol Gastrointest Liver Physiol 256: G335-G341, 1989.
31. Ray E, Avissar N, and Sax H. Growth factor regulation of enterocyte nutrient transport during intestinal adaptation. Am J Surg 183: 361-371, 2002.
32. + exchange in porcine jejunal enterocytes. Am J Physiol Gastrointest Liver Physiol 266: G828-G838, 1994.
33. Rhoads JM, Keku EO, Quinn J, Woosely J, and Lecce JG. L-glutamine stimulates jejunal sodium and chloride absorption in pig rotavirus enteritis. Gastroenterology 100: 683-691, 1991.
34. Rhoads M. Glutamine signaling in intestinal cells. JPEN J Parenter Enteral Nutr 23: S38-S40, 1999.
35. Ribeiro HJ, Ribeiro T, Mattos A, Palmeira C, Fernandez D, Sant'ana I, Rodrigues I, Hendicho T, and Fontaine O. Treatment of acute diarrhea with oral rehydration solutions containing glutamine. J Am Coll Nutr 13: 251-255, 1994.
36. Said HM, Van Voorhis K, Ghishan FK, Abumurad N, Nylander W, and Redha R. Transport characteristics of glutamine in human intestinal brush-border membrane vesicles. Am J Physiol Gastrointest Liver Physiol 256: G240-G245, 1989.
37. Silva AC, Santos-Neto MS, Soares AM, Fonteles M, Guerrant R, and Lima A. Efficacy of a glutamine-based oral rehydration solution on the electrolyte and water absorption in a rabbit model of secretory diarrhea induced by cholera toxin. J Pediatr Gastroenterol Nutr 26: 513-519, 1998.
38. 1: a dose-response study. Br J Clin Pharmacol 31: 433-437, 1991.
39. Souba WW. Nutritional support. N Engl J Med 336: 41-48, 1997.
40. Thillainayagam AV, Hunt JB, and Farthing MJG. Enhancing clinical efficacy of oral rehydration therapy: is low osmolality the key? Gastroenterology 114: 197-210, 1998.
41. Van Loon FP, Banik AK, Nath SK, Patra F, Wahed M, Darmaun D, Desjeux JF, and Mahalanabis D. The effect of L-glutamine on salt and water absorption: a jejunal perfusion study in cholera in humans. Eur J Gastroenterol Hepatol 8: 443-448, 1996.
42. Vidon N, Hecketsweiler P, Cortot A, and Bernier JJ. Study of the absorption of a elemental nutritive solution administered by continuous jejunal perfusion. Influence of flow rate and concentration on water-electrolyte movements. Gastroenterol Clin Biol 3: 257-266, 1979.