Transferrin conjugation confers mucosal molecular targeting to a model HIV-1 trimeric gp140 vaccine antigen

Journal of Controlled Release

Volumn 158, Issue 2, 2012, Pages 240-249

  Mann, J F S ^a,b   Stieh, D ^a   Klein, K ^a,b   De Stegmann, D S Miranda ^a   Cranage, M P ^a   Shattock, R J ^a,b   McKay, P F ^a,b  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Immunogenicity; Mucosal; Targeting; Transcytosis; Vaccine delivery

Indexed keywords

IMMUNOGENICITY; MUCOSAL; TARGETING; TRANSCYTOSIS; VACCINE DELIVERY;

ANTIGENS; PATHOGENS; VACCINES;

ORGANIC POLYMERS;

CD71 ANTIGEN; GLYCOPROTEIN GP 140; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TRANSFERRIN; TRANSFERRIN GLYCOPROTEIN GP 140 CONJUGATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG TARGETING; FEMALE; FEMALE GENITAL SYSTEM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN TISSUE; IMMUNOGENICITY; IMMUNOMODULATION; MOUSE; NONHUMAN; NOSE MUCOSA; PRIORITY JOURNAL; RECEPTOR AFFINITY; SINGLE DRUG DOSE; STROMA; VACCINATION;

ADMINISTRATION, INTRANASAL; ADMINISTRATION, INTRAVAGINAL; AIDS VACCINES; ANIMALS; ANTIGENS, VIRAL; CERVIX UTERI; ENV GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; FEMALE; HIV-1; HUMANS; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; MICE; MICE, INBRED BALB C; MUCOUS MEMBRANE; TRANSFERRIN; VAGINA;

EID: 84858700210     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.11.009     Document Type: Article

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