Recruitment of T cells to the lung in response to antigen challenge

Journal of Allergy and Clinical Immunology

Volumn 106, Issue 5 SUPPL., 2000, Pages

  Hamid, Qutayba A ^a   Cameron, Lisa A ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Asthma; Cytokines; Recruitment; T cells

Indexed keywords

ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ASTHMA; HUMAN; LUNG LAVAGE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE;

EID: 0033711943     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1067/mai.2000.110161     Document Type: Article

References (71)

1. Allergen-specific production of interferon-gamma by peripheral blood mononuclear cells and CD8 T cells in allergic disease and following immunotherapy
2. The pathology of asthma, with special reference to changes in the bronchial mucosa
3. Identification of T lymphocytes, macrophages, and activated eosinophils in the bronchial mucosa in intrinsic asthma: Relationship to symptoms and bronchial responsiveness
4. Inflammation of small airways in asthma
5. Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma
6. Increases in activated T lymphocytes, eosinophils, and cytokine mRNA expression for interleukin-5 and granulocyte/macrophage colony-stimulating factor in bronchial biopsies after allergen inhalation challenge in atopic asthmatics
7. Changes in T-lymphocyte subpopulations after antigenic bronchial provocation in asthmatics
8. Local allergen challenge and bronchoalveolar lavage of allergic asthmatic lungs: Description of the model and local airway inflammation
9. Dynamic T-cell changes in peripheral blood and bronchoalveolar lavage after antigen bronchoprovocation in asthmatics
10. Bronchial biopsy evidence for leukocyte infiltration and upregulation of leukocyte-endothelial, cell adhesion molecules 6 hours after local allergen challenge of sensitized asthmatic airways
11. Early changes in T lymphocytes recovered by bronchoalveolar lavage after local allergen challenge of asthmatic airways
12. Inflammatory and T-cell profile of asthmatic airways 6 hours after local allergen provocation
13. Cellular and mediator responses twenty-four hours after local endobronchial allergen challenge of asthmatic airways
14. Cloning T cells from sites of allergic inflammation
15. Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma
16. Predominant T(H)2-like bronchoalveolar T-lymphocyte population in atopic asthma
17. Relationships among numbers of bronchoalveolar lavage cells expressing messenger ribonucleic acid for cytokines, asthma symptoms, and airway methacholine responsiveness in atopic asthma
18. Expression of IL-12 and IL-13 mRNA in asthma and their modulation in response to steroid therapy
19. Cytokine mRNA expression in asthma is not restricted to the large airways
20. Phenotype of cells positive for interleukin-4 and interleukin-5 mRNA in allergic tissue reactions
21. Expression of IL-4, Cepsilon RNA, and Iepsilon RNA in the nasal mucosa of patients with seasonal rhinitis: Effect of topical corticosteroids
22. Interleukin-13 expression in the nasal mucosa of perennial allergic rhinitis
23. Differential in situ cytokine gene expression in acute versus chronic atopic dermatitis
24. Cytokine messenger RNA expression for IL-3, IL4, IL-5, and granulocyte/macrophage-colony-stimulating factor in the nasal mucosa after local allergen provocation: Relationship to tissue eosinophilia
25. Expression of epsilon germ-line gene transcripts and mRNA for the epsilon heavy chain of IgE in nasal B cells and the effects of topical corticosteroid
26. IL-13 m, RNA and immunoreactivity in allergen-induced rhinitis: Comparison with IL-4 expression and modulation by topical glucocorticold therapy
27. Increased interleukin-10 messenger RNA expression in atopic allergy and asthma
28. IL-13 expression at the sites of allergen challenge in patients with asthma
29. Late response to allergen is associated with increased concentrations of tumor necrosis factor-alpha and IL-5 in induced sputum
30. Kinetics of cell infiltration and cytokine messenger RNA expression after intradermal challenge with allergen and tuberculin in the same atopic individuals
31. T cells are the principal source of interleukin-5 mRNA in allergen-induced rhinitis
32. T lymphocytes and mast cells express messenger RNA for interleukin-4 in the nasal mucosa in allergen-induced rhinitis
33. Expression of IL-4 and IL-5 mRNA and protein product by CD4+ and CD8+ T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics
34. Activated mast cells produce interleukin 13
35. Identification of messenger RNA for IL-4 in human eosinophils with granule localization and release of the translated product
36. Prednisolone treatment in asthma: Reduction in the numbers of eosinophils, T cells, tryptase-only positive mast cells, and modulation of IL-4, IL-5, and interferon-gamma cytokine gene expression within the bronchial mucosa
37. Topical glucocorticosteroid (fluticasone propionate) inhibits cells expressing cytokine mRNA for interleukin-4 in the nasal mucosa in allergen-induced rhinitis
38. Chemoattractant lymphokines specific for the helper/inducer T-lymphocyte subset
39. CD4-mediated stimulation of human eosinophils: Lymphocyte chemoattractant factor and other CD4-binding ligands elicit eosinophil migration
40. Increased expression of interleukin-16 in bronchial mucosa of subjects with atopic asthma
41. Expression of IL-16 in allergen-induced late-phase nasal responses and relation to topical glucocorticosteroid treatment
42. + T-cell infiltration with increased IL- 16 gene expression in atopic dermatitis
43. IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothellum: Association with expression of VCAM-1
44. IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells
45. Effect of interleukin-2 on the airway response to antigen in the rat
46. Depletion of OX-8 lymphocytes from the blood and airways using monoclonal antibodies enhances the late airway response in rats
47. Effects of W3/25 monoclonal antibody on pulmonary inflammation and the late airway response (LR) in Brown-Norway (BN) rats
48. + T cells in brown Norway rats
49. Adoptively transferred late allergic airway responses are associated with Th2-type cytokines in the rat
50. Adoptively transferred late allergic response is inhibited by IL-4, but not IL-5, antisense oligonucleotide
51. CD4 T-lymphocyte activation in acute severe asthma: Relationship to disease severity and atopic status
52. Evidence for major basic protein immunoreactivity and interleukin 5 gene activation during the late phase response in explanted airways
53. Local cytokine messenger ribonucleic acid expression and in vitro allergic late phase responses in Brown-Norway rats
54. Cytokine expression after the topical administration of substance P to human nasal mucosa: The role of substance P in nasal allergy
55. Evidence for local eosinophil differentiation within allergic nasal mucosa: Inhibition with soluble IL-5 receptor
56. Local synthesis of ε germline gene transcripts, IL-4 and IL-13 in allergic nasal mucosa after ex vivo allergen exposure
57. IL-4 plays a dominant role in the differential development of Tho into Th1 and Th2 cells
58. IL-4 is an essential factor for the IgE synthesis induced in vitro by human T cell clones and their supernatants
59. Shifts in interleukin-4 and interferon-gamma production by T cells of patients with elevated serum IgE levels and the modulatory effects of these lymphokines on spontaneous IgE synthesis
60. The role of lymphocytes in allergic disease
61. Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE production
62. Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells
63. Human interleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: Comparison and interaction with IL-1, IL-3, IL-6, and GMCSF
64. Modulation of growth and differentiation of eosinophils from human peripheral blood CD34+ cells by IL5 and other growth factors
65. IL-5 but not interferon-gamma (IFN-gamma) inhibits eosinophil apoptosis by up-regulation of bcl-2 expression
66. Allergen-induced increases in IL-5 receptor alpha-subunit expression on bone marrow-derived CD34+ cells from asthmatic subjects: A novel marker of progenitor cell commitment towards eosinophilic differentiation
67. Upregulation of the transcription factor GATA-3 in upper airway mucosa after in vivo and in vitro allergen challenge
68. GM-CSF, IL-8, IL-1R, TNF-alpha R, and HLA-DR in nasal epithelial cells in allergic rhinitis
69. Mechanisms of allergic pulmonary eosinophiha in the mouse
70. Allergen-induced increase in bone marrow progenitors in airway hyperresponsive dogs: Regulation by a serum hemopoietic factor
71. Interleukin-5 expression in the bone marrow of sensitized Balb/c mice after allergen challenge