메뉴 건너뛰기




Volumn 18, Issue SUPPL. 1, 2012, Pages

Genetic reduction of the E3 ubiquitin ligase element, SKP1A and environmental manipulation to emulate cardinal features of Parkinson's disease

Author keywords

Disease model; Dopaminergic markers; SCF E3 complex; Short hairpin RNA lentiviruses; Sporadic Parkinson's disease

Indexed keywords

ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE ISOENZYME 1; DOPAMINE; LENTIVIRUS VECTOR; SHORT HAIRPIN RNA; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

EID: 84858667409     PISSN: 13538020     EISSN: 18735126     Source Type: Journal    
DOI: 10.1016/s1353-8020(11)70055-4     Document Type: Article
Times cited : (10)

References (20)
  • 1
    • 79953839752 scopus 로고    scopus 로고
    • Gene-environment interactions: key to unraveling themystery of Parkinson's disease
    • Gao HM, Hong JS. Gene-environment interactions: key to unraveling themystery of Parkinson's disease. Progr Neurobiol 2011;94:1-19.
    • (2011) Progr Neurobiol , vol.94 , pp. 1-19
    • Gao, H.M.1    Hong, J.S.2
  • 2
    • 77956226230 scopus 로고    scopus 로고
    • Gene-environment interactions in Parkinson's disease and other forms of parkinsonism
    • Vance JM, Ali S, Bradley WG, Singer C, Di Monte DA. Gene-environment interactions in Parkinson's disease and other forms of parkinsonism. Neurotoxicology 2010;31:598-602.
    • (2010) Neurotoxicology , vol.31 , pp. 598-602
    • Vance, J.M.1    Ali, S.2    Bradley, W.G.3    Singer, C.4    Di Monte, D.A.5
  • 3
  • 4
    • 42149180679 scopus 로고    scopus 로고
    • Polymorphism in environment responsive genes and association with Parkinson disease
    • Singh M, Khan AJ, Shah PP, Shukla R, Khanna VK, Parmar D. Polymorphism in environment responsive genes and association with Parkinson disease. Mol Cell Biochem 2008;312:131-8.
    • (2008) Mol Cell Biochem , vol.312 , pp. 131-138
    • Singh, M.1    Khan, A.J.2    Shah, P.P.3    Shukla, R.4    Khanna, V.K.5    Parmar, D.6
  • 5
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: mechanisms and models
    • Dauer W, Przedborski S. Parkinson's disease: mechanisms and models. Neuron 2003;39:889-909.
    • (2003) Neuron , vol.39 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 7
    • 57649155208 scopus 로고    scopus 로고
    • Oxidative stress in Parkinson's disease: a mechanism of pathogenic and therapeutic significance
    • Zhou C, Huang Y, Przedborski S. Oxidative stress in Parkinson's disease: a mechanism of pathogenic and therapeutic significance. Ann NY Acad Sci 2008;1147:93-104.
    • (2008) Ann NY Acad Sci , vol.1147 , pp. 93-104
    • Zhou, C.1    Huang, Y.2    Przedborski, S.3
  • 8
    • 79953048063 scopus 로고    scopus 로고
    • Biomarkers for prediction and targeted prevention of Alzheimer's and Parkinson's diseases: evaluation of drug clinical efficacy
    • Mandel S, Morelli M, Halperin I, Korczyn AD. Biomarkers for prediction and targeted prevention of Alzheimer's and Parkinson's diseases: evaluation of drug clinical efficacy. EPMA J 2010;1(2):273-92.
    • (2010) EPMA J , vol.1 , Issue.2 , pp. 273-292
    • Mandel, S.1    Morelli, M.2    Halperin, I.3    Korczyn, A.D.4
  • 9
    • 19944428747 scopus 로고    scopus 로고
    • Gene expression profiling of parkinsonian substantia nigra pars compacta; alterations in ubiquitin-proteasome, heat shock protein, iron and oxidative stress regulated proteins, cell adhesion/cellular matrix and vesicle trafficking genes
    • Grunblatt E, Mandel S, Jacob-Hirsch J, Zeligson S, Amariglo N, Rechavi G, et al. Gene expression profiling of parkinsonian substantia nigra pars compacta; alterations in ubiquitin-proteasome, heat shock protein, iron and oxidative stress regulated proteins, cell adhesion/cellular matrix and vesicle trafficking genes. J Neural Transm 2004;111:1543-73.
    • (2004) J Neural Transm , vol.111 , pp. 1543-1573
    • Grunblatt, E.1    Mandel, S.2    Jacob-Hirsch, J.3    Zeligson, S.4    Amariglo, N.5    Rechavi, G.6
  • 10
    • 38949125133 scopus 로고    scopus 로고
    • Gene and protein signatures in sporadic Parkinson's disease and a novel genetic model of PD
    • Mandel SA, Fishman T, Youdim MB. Gene and protein signatures in sporadic Parkinson's disease and a novel genetic model of PD. Parkinsonism Relat Disord 2007;13(Suppl 3):S242-7.
    • (2007) Parkinsonism Relat Disord , vol.13 , Issue.SUPPL. 3
    • Mandel, S.A.1    Fishman, T.2    Youdim, M.B.3
  • 11
    • 70450280570 scopus 로고    scopus 로고
    • A sporadic Parkinson's disease model via silencing of the ubiquitin-proteasome/E3-ligase component
    • Fishman-Jacob T, Reznichenko L, Youdim MB, Mandel SA. A sporadic Parkinson's disease model via silencing of the ubiquitin-proteasome/E3-ligase component, SKP1A. J Biol Chem 2009;284(47):32835-45.
    • (2009) SKP1A. J Biol Chem , vol.284 , Issue.47 , pp. 32835-32845
    • Fishman-Jacob, T.1    Reznichenko, L.2    Youdim, M.B.3    Mandel, S.A.4
  • 12
    • 18344391432 scopus 로고    scopus 로고
    • Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex
    • Zheng N, Schulman BA, Song L, Miller JJ, Jeffrey PD, Wang P, et al. Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature 2002;416: 703-9.
    • (2002) Nature , vol.416 , pp. 703-709
    • Zheng, N.1    Schulman, B.A.2    Song, L.3    Miller, J.J.4    Jeffrey, P.D.5    Wang, P.6
  • 13
    • 59649088353 scopus 로고    scopus 로고
    • Correia Guedes L, et al. FBXO7 mutations cause autosomal recessive, early-onset parkinsonianpyramidal syndrome
    • Di Fonzo A, Dekker MC, Montagna P, Baruzzi A, Yonova EH, Correia Guedes L, et al. FBXO7 mutations cause autosomal recessive, early-onset parkinsonianpyramidal syndrome. Neurology 2009;72:240-5.
    • (2009) Neurology , vol.72 , pp. 240-245
    • Di Fonzo, A.1    Dekker, M.C.2    Montagna, P.3    Baruzzi, A.4    Yonova, E.H.5
  • 14
    • 34248359919 scopus 로고    scopus 로고
    • Selective cochlear degeneration in mice lacking the F-box protein, Fbx2, a glycoproteinspecific ubiquitin ligase subunit
    • Nelson RF, Glenn KA, Zhang Y, Wen H, Knutson T, Gouvion CM, et al. Selective cochlear degeneration in mice lacking the F-box protein, Fbx2, a glycoproteinspecific ubiquitin ligase subunit. J Neurosci 2007;27:5163-71.
    • (2007) J Neurosci , vol.27 , pp. 5163-5171
    • Nelson, R.F.1    Glenn, K.A.2    Zhang, Y.3    Wen, H.4    Knutson, T.5    Gouvion, C.M.6
  • 15
    • 0037378026 scopus 로고    scopus 로고
    • Oxidative stress in Parkinson's disease
    • discussion:S-8
    • Jenner P. Oxidative stress in Parkinson's disease. Ann Neurol 2003;53(Suppl 3): S26-36; discussion
    • (2003) Ann Neurol , vol.53 , Issue.SUPPL. 3
    • Jenner, P.1
  • 16
    • 0037361388 scopus 로고    scopus 로고
    • Molecular mechanisms of selective dopaminergic neuronal death in Parkinson's disease
    • Barzilai A, Melamed E. Molecular mechanisms of selective dopaminergic neuronal death in Parkinson's disease. Trends Mol Med 2003;9:126-32.
    • (2003) Trends Mol Med , vol.9 , pp. 126-132
    • Barzilai, A.1    Melamed, E.2
  • 17
    • 76749132743 scopus 로고    scopus 로고
    • Silencing/overexpressing selected genes as a model of sporadic Parkinson's disease
    • Fishman-Jacob T, Youdim MB, Mandel SA. Silencing/overexpressing selected genes as a model of sporadic Parkinson's disease. Neurodegener Dis 2010;7: 108-11.
    • (2010) Neurodegener Dis , vol.7 , pp. 108-111
    • Fishman-Jacob, T.1    Youdim, M.B.2    Mandel, S.A.3
  • 19
    • 34548400209 scopus 로고    scopus 로고
    • Model fusion, the next phase in developing animal models for Parkinson's disease
    • Manning-Bog AB, Langston JW. Model fusion, the next phase in developing animal models for Parkinson's disease. Neurotox Res 2007;11:219-40.
    • (2007) Neurotox Res , vol.11 , pp. 219-240
    • Manning-Bog, A.B.1    Langston, J.W.2
  • 20
    • 58149149970 scopus 로고    scopus 로고
    • Parkin deficiency increases vulnerability to inflammation-related nigral degeneration
    • Frank-Cannon TC, Tran T, Ruhn KA, Martinez TN, Hong J, Marvin M, et al. Parkin deficiency increases vulnerability to inflammation-related nigral degeneration. J Neurosci 2008;28:10825-34.
    • (2008) J Neurosci , vol.28 , pp. 10825-10834
    • Frank-Cannon, T.C.1    Tran, T.2    Ruhn, K.A.3    Martinez, T.N.4    Hong, J.5    Marvin, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.