Comparison of silk-elastinlike protein polymer hydrogel and poloxamer in matrix-mediated gene delivery

International Journal of Pharmaceutics

Volumn 427, Issue 1, 2012, Pages 97-104

  Price, Robert ^a   Gustafson, Joshua ^a,b   Greish, Khaled ^a,d   Cappello, Joseph ^a   McGill, Lawrence ^c   Ghandehari, Hamidreza ^a,b  

^a UNIVERSITY OF UTAH   (United States)

^b University of Utah   (United States)

^c ARUP LABORATORIES   (United States)

^d UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Gene delivery; Head and neck cancer; Poloxomers; Protein polymers; Silk elastinlike polymers

Indexed keywords

COPOLYMER; ELASTIN; POLOXAMER; VIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; BODY WEIGHT; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG ABSORPTION; DRUG EFFICACY; DRUG SAFETY; ENCAPSULATION; FEMALE; GENE EXPRESSION; HEAD AND NECK CARCINOMA; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HYDROGEL; IMMUNOCOMPETENCE; INJECTION SITE INFLAMMATION; LEUKOCYTOSIS; MOUSE; NONHUMAN; POLYMER DIRECTED ENZYME PRODRUG THERAPY; PRIORITY JOURNAL; SILK; SURVIVAL; TUMOR VOLUME; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; VIRUS GENE;

ADENOVIRIDAE; ANIMALS; BLOOD CHEMICAL ANALYSIS; ELASTIN; FEMALE; GANCICLOVIR; GENE THERAPY; GENE TRANSFER TECHNIQUES; HEAD AND NECK NEOPLASMS; HUMANS; HYDROGEL; MICE; MICE, NUDE; POLOXAMER; PRODRUGS; PROTEINS; SILK; TREATMENT OUTCOME; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84858634572     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.09.037     Document Type: Article

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