Silk-elastinlike protein polymers improve the efficacy of adenovirus thymidine kinase enzyme prodrug therapy of head and neck tumors

Journal of Gene Medicine

Volumn 12, Issue 7, 2010, Pages 572-579

  Greish, Khaled ^a   Frandsen, Jordan ^a,b   Scharff, Stephanie ^a,c   Gustafson, Joshua ^a,b   Cappello, Joseph ^d   Li, Daqing ^e   O'Malley Jr , Bert W ^e   Ghandehari, Hamidreza ^a,b  

^a UNIVERSITY OF UTAH   (United States)

^b Department of Electrical and Computer Engineering   (United States)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

^d Protein Polymer Technologies Inc   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Adenovirus; Gene therapy; Head and neck tumors; Hydrogel; Silk elastinlike polymers

Indexed keywords

ANTINEOPLASTIC AGENT; ELASTIN; LUCIFERASE; PRODRUG; SILK ELASTINLIKE PROTEIN POLYMER; THYMIDINE KINASE; UNCLASSIFIED DRUG; BIOPOLYMER; HYBRID PROTEIN; SILK-ELASTINLIKE PROTEIN 47K;

ARTICLE; BIOLUMINESCENCE; BLOOD CELL COUNT; CANCER THERAPY; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; FEMALE; GENE EXPRESSION; HEAD AND NECK CANCER; HEAD AND NECK TUMOR; HISTOLOGY; HYDROGEL; KIDNEY FUNCTION; LIVER FUNCTION; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN POLYMERIZATION; SILK; TUMOR GROWTH; TUMOR VOLUME; WEIGHT CHANGE; ADENOVIRIDAE; ANIMAL; DRUG SCREENING; GENE THERAPY; GENETICS; HEAD AND NECK NEOPLASMS; KIDNEY FUNCTION TEST; LIVER FUNCTION TEST; LUMINESCENCE; METABOLISM; THREE DIMENSIONAL IMAGING; TREATMENT OUTCOME;

ADENOVIRIDAE; ANIMALS; BIOPOLYMERS; GENE THERAPY; HEAD AND NECK NEOPLASMS; IMAGING, THREE-DIMENSIONAL; KIDNEY FUNCTION TESTS; LIVER FUNCTION TESTS; LUCIFERASES; LUMINESCENT MEASUREMENTS; MICE; MICE, NUDE; PRODRUGS; RECOMBINANT FUSION PROTEINS; THYMIDINE KINASE; TREATMENT OUTCOME; XENOGRAFT MODEL ANTITUMOR ASSAYS; GENETIC THERAPY;

ADENOVIRIDAE; MUS; MUS MUSCULUS;

EID: 77955236873     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1469     Document Type: Article

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