Influence of Solute Charge and Hydrophobicity on Partitioning and Diffusion in a Genetically Engineered Silk-Elastin-Like Protein Polymer Hydrogel

Macromolecular Bioscience

Volumn 10, Issue 10, 2010, Pages 1235-1247

  Dinerman, Adam A ^a,b   Cappello, Joseph ^d   El Sayed, Mohamed ^a,c   Hoag, Stephen W ^a   Ghandehari, Hamidreza ^a,e  

^a UNIVERSITY OF MARYLAND   (United States)

^b CENTOCOR INC   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

^d Protein Polymer Technologies Inc   (United States)

^e UNIVERSITY OF UTAH   (United States)

Author keywords

Dendrimers; Diffusion; Drug delivery; Genetically engineered polymers; Hydrogels

Indexed keywords

CROSS-LINKED NETWORKS; DIFFUSION PROPERTIES; ELASTIN-LIKE PROTEINS; FLUORESCENT DYES; GENETICALLY ENGINEERED POLYMERS; RELEASE BEHAVIORS;

DENDRIMERS; DIFFUSION; DRUG DELIVERY; GENETIC ENGINEERING; GLYCOPROTEINS; HYDROPHOBICITY; PROBES; SCALES (WEIGHING INSTRUMENTS); SILK;

HYDROGELS;

AMINE; DENDRIMER; ELASTIN; FLUORESCEIN ISOTHIOCYANATE; FLUORESCENT DYE; POLYMER;

ARTICLE; DIFFUSION; ELECTRICITY; GENETIC ENGINEERING; HYDROGEL; HYDROPHOBICITY; PHASE PARTITIONING; PROTEIN POLYMERIZATION; SILK; SOLUTE; SURFACE CHARGE;

AMINO ACID SEQUENCE; BIOCOMPATIBLE MATERIALS; DENDRIMERS; DIFFUSION; ELASTIN; FLUORESCENT DYES; GENETIC ENGINEERING; HYDROGELS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MATERIALS TESTING; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; POLYMERS; SILK; SOLUTIONS;

EID: 78349293855     PISSN: 16165187     EISSN: 16165195     Source Type: Journal    
DOI: 10.1002/mabi.201000061     Document Type: Article

References (23)

1. J. Cappello, J. W. Crissman, M. Crissman, F. A. Ferrari, G. Textor, O. Wallis, J. R. Whitledge, X. Zhou, D. Burman, L. Aukerman, E. R. Stedronsky, J. Controlled Release 1998, 53, 105.
2. R. A. McMillan, V. P. Conticello, Macromolecules 2000, 33, 4809.
3. W. A. Petka, J. L. Harden, K. P. McGrath, D. Wirtz, D. A. Tirrell, Science 1998, 281, 389.
4. J. Lee, C. W. Macosko, D. W. Urry, Macromolecules 2001, 34, 4114.
5. D. W. Urry, C. M. Harris, C. X. Luan, C. Luan, "Controlled Drug Delivery-Strategies and Challenges", American Chemical Society, Washington 1997, p. 405.
6. M. Haider, Z. Megeed, H. Ghandehari, J. Controlled Release 2004, 95, 1.
7. Z. Megeed, J. Cappello, H. Ghandehari, Adv. Drug Delivery Rev. 2002, 54, 1075.
8. A. A. Dinerman, J. Cappello, H. Ghandehari, S. W. Hoag, Biomaterials 2002, 23, 4203.
9. A. A. Dinerman, J. Cappello, H. Ghandehari, S. W. Hoag, J. Controlled Release 2002, 82, 277.
10. Z. Megeed, J. Cappello, H. Ghandehari, Pharm. Res. 2002, 19, 954.
11. D. A. Tomalia, A. M. Naylor, W. A. Goddard, Angew. Chem. Int. Ed. Engl. 1990, 29, 138.
12. M. El-Sayed, M. F. Kiani, M. D. Naimark, A. H. Hikal, H. Ghandehari, Pharm. Res. 2001, 18, 23.
13. J. C. Fu, C. Hagemeir, D. L. Moyer, E. W. Ng, J. Biomed. Mater. Res. 1976, 10, 743.
14. J. Siepmann, A. Ainaoui, J. M. Vergnaud, R. Bodmeier, J. Pharm. Sci. 1998, 87, 827.
15. P. L. Ritger, N. A. Peppas, J. Controlled Release 1987, 5, 37.
16. M. P. Singh, J. A. Lumpkin, J. Rosenblatt, J. Controlled Release 1995, 35, 165.
17. L. E. Weaver, G. Carta, Biotechnol. Prog. 1996, 12, 342.
18. H. Komiyama, J. M. Smith, AIChE J. 1974, 20, 728.
19. R. Dandu, H. Ghandehari, Prog. Polym. Sci. 2007, 32, 1008.
20. J. Gustafson, K. Greish, J. Frandsen, J. Cappello, H. Ghandehari, J. Controlled Release 2009, 140, 256.
21. M. Haider, J. Cappello, H. Ghandehari, K. W. Leong, Pharm. Res. 2008, 25, 692.
22. M. Araie, D. Maurice, Exp. Eye Res. 1987, 44, 73.
23. W. M. Saltzman, M. L. Radomsky, K. J. Whaley, R. A. Cone, Biophys. J. 1994, 66, 508.