Transcriptional responses of zebrafish embryos exposed to potential sonic hedgehog pathway interfering compounds deviate from expression profiles of cyclopamine

Reproductive Toxicology

Volumn 33, Issue 2, 2012, Pages 254-263

  Büttner, Anita ^a   Busch, Wibke ^b   Klüver, Nils ^b   Giannis, Athanassios ^a   Scholz, Stefan ^b  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

Author keywords

Cyclopamine; GANT 61; Hedgehog; Hspb11; SANT 2; Zebrafish

Indexed keywords

CYCLOPAMINE; GLI ANTAGONIST 61; PROTEIN INHIBITOR; SMOOTHENED ANTAGONIST 2; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYCLOPIA; DEVELOPMENTAL DISORDER; DOWN REGULATION; EMBRYO; EMBRYO DEATH; EMBRYOTOXICITY; GENE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REPRESSION; GENETIC TRANSCRIPTION; HSPB11 GENE; LC 50; MICROARRAY ANALYSIS; NONHUMAN; PHENOTYPE; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; ZEBRA FISH;

ANIMALS; BENZAMIDES; BENZIMIDAZOLES; EMBRYO, NONMAMMALIAN; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEDGEHOG PROTEINS; PYRIDINES; PYRIMIDINES; TRANSCRIPTION, GENETIC; VERATRUM ALKALOIDS; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO RERIO; ERINACEIDAE;

EID: 84858621540     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2011.12.010     Document Type: Article

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