Differential mRNA expression of acetylcholinesterase in the central nervous system of rats with acute and chronic exposure of sarin & physostigmine

Journal of Applied Toxicology

Volumn 29, Issue 5, 2009, Pages 386-394

  Bansal, Iti ^a   Waghmare, C K ^a   Anand, T ^a   Gupta, A K ^a   Bhattacharya, B K ^a  

^a DEFENCE RESEARCH AND DEVELOPMENT ESTABLISHMENT   (India)

Author keywords

Acetylcholinesterase; mRNA expression; Nerve agent; Organophosphates; Physostigmine; Sarin

Indexed keywords

ACETYLCHOLINESTERASE; BUTYLCHOLINESTERASE; ISOENZYME; MESSENGER RNA; PHYSOSTIGMINE; SARIN; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CHOLINERGIC TRANSMISSION; CHRONIC TOXICITY; CONTROLLED STUDY; DRUG EXPOSURE; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME INHIBITION; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; LD 50; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; WISTAR RAT;

ACETYLCHOLINESTERASE; ACUTE TOXICITY TESTS; ANIMALS; BRAIN; BUTYRYLCHOLINESTERASE; CHEMICAL WARFARE AGENTS; CHOLINESTERASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION; INJECTIONS, INTRAMUSCULAR; INJECTIONS, SUBCUTANEOUS; LETHAL DOSE 50; PHYSOSTIGMINE; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SARIN; TIME FACTORS; TOXICITY TESTS, CHRONIC;

RATTUS;

EID: 67651173003     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1424     Document Type: Article

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