Translocation of a bak C-Terminus mutant from cytosol to mitochondria to mediate cytochrome c release: Implications for bak and bax apoptotic function

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Ferrer, Pedro Eitz ^a,c   Frederick, Paul ^a,d   Gulbis, Jacqueline M ^a,b   Dewson, Grant ^a,b   Kluck, Ruth M ^a,b  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C; PROTEIN BAK; PROTEIN BAX; PROTEIN BID; PROTEIN MCL 1; BAK1 PROTEIN, MOUSE; BAX PROTEIN, MOUSE; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; PROTEIN BCL 2;

AMINO ACID SUBSTITUTION; ANIMAL CELL; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOSOL; EMBRYO; ENZYME RELEASE; HYDROPHOBICITY; MITOCHONDRION; MOUSE; NONHUMAN; OLIGOMERIZATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STABILITY; PROTEIN TARGETING; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; GENETICS; METABOLISM; MOUSE MUTANT; MUTATION; PHYSIOLOGY; PROTEIN TRANSPORT;

ANIMALS; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; CELL LINE, TRANSFORMED; CYTOCHROMES C; CYTOSOL; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MUTATION; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 84858590503     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031510     Document Type: Article

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