-
1
-
-
33947731008
-
Mighty Piwis defend the germline against genome intruders
-
O'Donnell KA, Boeke JD, (2007) Mighty Piwis defend the germline against genome intruders. Cell 129: 37-44.
-
(2007)
Cell
, vol.129
, pp. 37-44
-
-
O'Donnell, K.A.1
Boeke, J.D.2
-
2
-
-
34247525481
-
piRNAs in the germ line
-
Lin H, (2007) piRNAs in the germ line. Science 316: 397.
-
(2007)
Science
, vol.316
, pp. 397
-
-
Lin, H.1
-
3
-
-
34249805994
-
The coming of age for Piwi proteins
-
Seto AG, Kingston RE, Lau NC, (2007) The coming of age for Piwi proteins. Mol Cell 26: 603-609.
-
(2007)
Mol Cell
, vol.26
, pp. 603-609
-
-
Seto, A.G.1
Kingston, R.E.2
Lau, N.C.3
-
4
-
-
0035863870
-
Human CD34(+) stem cells express the hiwi gene, a human homologue of the Drosophila gene piwi
-
Sharma AK, Nelson MC, Brandt JE, Wessman M, Mahmud N, et al. (2001) Human CD34(+) stem cells express the hiwi gene, a human homologue of the Drosophila gene piwi. Blood 97: 426-434.
-
(2001)
Blood
, vol.97
, pp. 426-434
-
-
Sharma, A.K.1
Nelson, M.C.2
Brandt, J.E.3
Wessman, M.4
Mahmud, N.5
-
5
-
-
36749037521
-
The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race
-
Aravin AA, Hannon GJ, Brennecke J, (2007) The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race. Science 318: 761-764.
-
(2007)
Science
, vol.318
, pp. 761-764
-
-
Aravin, A.A.1
Hannon, G.J.2
Brennecke, J.3
-
6
-
-
33947273235
-
Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila
-
Brennecke J, Aravin AA, Stark A, Dus M, Kellis M, et al. (2007) Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell 128: 1089-1103.
-
(2007)
Cell
, vol.128
, pp. 1089-1103
-
-
Brennecke, J.1
Aravin, A.A.2
Stark, A.3
Dus, M.4
Kellis, M.5
-
7
-
-
52049098967
-
A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice
-
Aravin AA, Sachidanandam R, Bourc'his D, Schaefer C, Pezic D, et al. (2008) A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice. Mol Cell 31: 785-799.
-
(2008)
Mol Cell
, vol.31
, pp. 785-799
-
-
Aravin, A.A.1
Sachidanandam, R.2
Bourc'his, D.3
Schaefer, C.4
Pezic, D.5
-
8
-
-
33947720638
-
MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline
-
Carmell MA, Girard A, van de Kant HJ, Bourc'his D, Bestor TH, et al. (2007) MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline. Dev Cell 12: 503-514.
-
(2007)
Dev Cell
, vol.12
, pp. 503-514
-
-
Carmell, M.A.1
Girard, A.2
van de Kant, H.J.3
Bourc'his, D.4
Bestor, T.H.5
-
9
-
-
67349141725
-
Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profile
-
Reuter M, Chuma S, Tanaka T, Franz T, Stark A, et al. (2009) Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profile. Nat Struct Mol Biol 16: 639-646.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 639-646
-
-
Reuter, M.1
Chuma, S.2
Tanaka, T.3
Franz, T.4
Stark, A.5
-
10
-
-
79953089167
-
PIWI-interacting small RNAs: the vanguard of genome defence
-
Siomi MC, Sato K, Pezic D, Aravin AA, (2011) PIWI-interacting small RNAs: the vanguard of genome defence. Nat Rev Mol Cell Biol 12: 246-258.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 246-258
-
-
Siomi, M.C.1
Sato, K.2
Pezic, D.3
Aravin, A.A.4
-
11
-
-
0037030522
-
Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas
-
Qiao D, Zeeman AM, Deng W, Looijenga LH, Lin H, (2002) Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas. Oncogene 21: 3988-3999.
-
(2002)
Oncogene
, vol.21
, pp. 3988-3999
-
-
Qiao, D.1
Zeeman, A.M.2
Deng, W.3
Looijenga, L.H.4
Lin, H.5
-
12
-
-
53049109462
-
The stem cell-associated Hiwi gene in human adenocarcinoma of the pancreas: expression and risk of tumour-related death
-
Grochola LF, Greither T, Taubert H, Moller P, Knippschild U, et al. (2008) The stem cell-associated Hiwi gene in human adenocarcinoma of the pancreas: expression and risk of tumour-related death. Br J Cancer 99: 1083-1088.
-
(2008)
Br J Cancer
, vol.99
, pp. 1083-1088
-
-
Grochola, L.F.1
Greither, T.2
Taubert, H.3
Moller, P.4
Knippschild, U.5
-
13
-
-
33645226840
-
Expression of hiwi gene in human gastric cancer was associated with proliferation of cancer cells
-
Liu X, Sun Y, Guo J, Ma H, Li J, et al. (2006) Expression of hiwi gene in human gastric cancer was associated with proliferation of cancer cells. Int J Cancer 118: 1922-1929.
-
(2006)
Int J Cancer
, vol.118
, pp. 1922-1929
-
-
Liu, X.1
Sun, Y.2
Guo, J.3
Ma, H.4
Li, J.5
-
14
-
-
74049085017
-
Expression of HIWI in human esophageal squamous cell carcinoma is significantly associated with poorer prognosis
-
He W, Wang Z, Wang Q, Fan Q, Shou C, et al. (2009) Expression of HIWI in human esophageal squamous cell carcinoma is significantly associated with poorer prognosis. BMC Cancer 9: 426.
-
(2009)
BMC Cancer
, vol.9
, pp. 426
-
-
He, W.1
Wang, Z.2
Wang, Q.3
Fan, Q.4
Shou, C.5
-
15
-
-
33847044299
-
Expression of the stem cell self-renewal gene Hiwi and risk of tumour-related death in patients with soft-tissue sarcoma
-
Taubert H, Greither T, Kaushal D, Wurl P, Bache M, et al. (2007) Expression of the stem cell self-renewal gene Hiwi and risk of tumour-related death in patients with soft-tissue sarcoma. Oncogene 26: 1098-1100.
-
(2007)
Oncogene
, vol.26
, pp. 1098-1100
-
-
Taubert, H.1
Greither, T.2
Kaushal, D.3
Wurl, P.4
Bache, M.5
-
16
-
-
34248160438
-
Developmentally regulated piRNA clusters implicate MILI in transposon control
-
Aravin AA, Sachidanandam R, Girard A, Fejes-Toth K, Hannon GJ, (2007) Developmentally regulated piRNA clusters implicate MILI in transposon control. Science 316: 744-747.
-
(2007)
Science
, vol.316
, pp. 744-747
-
-
Aravin, A.A.1
Sachidanandam, R.2
Girard, A.3
Fejes-Toth, K.4
Hannon, G.J.5
-
17
-
-
70350489124
-
Characterization and comparison of the properties of sarcoma cell lines in vitro and in vivo
-
Mills J, Matos T, Charytonowicz E, Hricik T, Castillo-Martin M, et al. (2009) Characterization and comparison of the properties of sarcoma cell lines in vitro and in vivo. Hum Cell 22: 85-93.
-
(2009)
Hum Cell
, vol.22
, pp. 85-93
-
-
Mills, J.1
Matos, T.2
Charytonowicz, E.3
Hricik, T.4
Castillo-Martin, M.5
-
18
-
-
36049042525
-
Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway
-
Matushansky I, Hernando E, Socci ND, Mills JE, Matos TA, et al. (2007) Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway. J Clin Invest 117: 3248-3257.
-
(2007)
J Clin Invest
, vol.117
, pp. 3248-3257
-
-
Matushansky, I.1
Hernando, E.2
Socci, N.D.3
Mills, J.E.4
Matos, T.A.5
-
19
-
-
34249890232
-
Is Ewing's sarcoma a stem cell tumor?
-
Meltzer PS, (2007) Is Ewing's sarcoma a stem cell tumor? Cell Stem Cell 1: 13-15.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 13-15
-
-
Meltzer, P.S.1
-
20
-
-
0034084930
-
Identification of a prx1 limb enhancer
-
Martin JF, Olson EN, (2000) Identification of a prx1 limb enhancer. Genesis 26: 225-229.
-
(2000)
Genesis
, vol.26
, pp. 225-229
-
-
Martin, J.F.1
Olson, E.N.2
-
21
-
-
0036076389
-
Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer
-
Logan M, Martin JF, Nagy A, Lobe C, Olson EN, et al. (2002) Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer. Genesis 33: 77-80.
-
(2002)
Genesis
, vol.33
, pp. 77-80
-
-
Logan, M.1
Martin, J.F.2
Nagy, A.3
Lobe, C.4
Olson, E.N.5
-
22
-
-
0037298161
-
Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouse
-
Lane N, Dean W, Erhardt S, Hajkova P, Surani A, et al. (2003) Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouse. Genesis 35: 88-93.
-
(2003)
Genesis
, vol.35
, pp. 88-93
-
-
Lane, N.1
Dean, W.2
Erhardt, S.3
Hajkova, P.4
Surani, A.5
-
23
-
-
42049099673
-
A developmental model of sarcomagenesis defines a differentiation-based classification for liposarcomas
-
Matushansky I, Hernando E, Socci ND, Matos T, Mills J, et al. (2008) A developmental model of sarcomagenesis defines a differentiation-based classification for liposarcomas. Am J Pathol 172: 1069-1080.
-
(2008)
Am J Pathol
, vol.172
, pp. 1069-1080
-
-
Matushansky, I.1
Hernando, E.2
Socci, N.D.3
Matos, T.4
Mills, J.5
-
24
-
-
0036844418
-
Primary adult soft tissue sarcoma: time-dependent influence of prognostic variables
-
Stojadinovic A, Leung DH, Allen P, Lewis JJ, Jaques DP, et al. (2002) Primary adult soft tissue sarcoma: time-dependent influence of prognostic variables. J Clin Oncol 20: 4344-4352.
-
(2002)
J Clin Oncol
, vol.20
, pp. 4344-4352
-
-
Stojadinovic, A.1
Leung, D.H.2
Allen, P.3
Lewis, J.J.4
Jaques, D.P.5
-
25
-
-
70349985246
-
Targeted mutation of p53 and Rb in mesenchymal cells of the limb bud produces sarcomas in mice
-
Lin PP, Pandey MK, Jin F, Raymond AK, Akiyama H, et al. (2009) Targeted mutation of p53 and Rb in mesenchymal cells of the limb bud produces sarcomas in mice. Carcinogenesis 30: 1789-1795.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1789-1795
-
-
Lin, P.P.1
Pandey, M.K.2
Jin, F.3
Raymond, A.K.4
Akiyama, H.5
-
26
-
-
79951818091
-
Chromatin structure predicts epigenetic therapy responsiveness in sarcoma
-
Mills J, Hricik T, Siddiqi S, Matushansky I, (2011) Chromatin structure predicts epigenetic therapy responsiveness in sarcoma. Mol Cancer Ther 10: 313-324.
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 313-324
-
-
Mills, J.1
Hricik, T.2
Siddiqi, S.3
Matushansky, I.4
-
27
-
-
33846115005
-
CancerGenes: a gene selection resource for cancer genome projects
-
Higgins ME, Claremont M, Major JE, Sander C, Lash AE, (2007) CancerGenes: a gene selection resource for cancer genome projects. Nucleic Acids Res 35: D721-726.
-
(2007)
Nucleic Acids Res
, vol.35
-
-
Higgins, M.E.1
Claremont, M.2
Major, J.E.3
Sander, C.4
Lash, A.E.5
-
28
-
-
33751363185
-
Aberrant expression of the Rb pathway proteins in soft tissue sarcomas
-
Sabah M, Cummins R, Leader M, Kay E, (2006) Aberrant expression of the Rb pathway proteins in soft tissue sarcomas. Appl Immunohistochem Mol Morphol 14: 397-403.
-
(2006)
Appl Immunohistochem Mol Morphol
, vol.14
, pp. 397-403
-
-
Sabah, M.1
Cummins, R.2
Leader, M.3
Kay, E.4
-
29
-
-
74249101368
-
Cytoplasmic compartmentalization of the fetal piRNA pathway in mice
-
Aravin AA, van der Heijden GW, Castaneda J, Vagin VV, Hannon GJ, et al. (2009) Cytoplasmic compartmentalization of the fetal piRNA pathway in mice. PLoS Genet 5: e1000764.
-
(2009)
PLoS Genet
, vol.5
-
-
Aravin, A.A.1
van der Heijden, G.W.2
Castaneda, J.3
Vagin, V.V.4
Hannon, G.J.5
-
30
-
-
0036083480
-
miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis
-
Deng W, Lin H, (2002) miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis. Dev Cell 2: 819-830.
-
(2002)
Dev Cell
, vol.2
, pp. 819-830
-
-
Deng, W.1
Lin, H.2
-
31
-
-
33748602389
-
MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis
-
Grivna ST, Pyhtila B, Lin H, (2006) MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis. Proc Natl Acad Sci U S A 103: 13415-13420.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 13415-13420
-
-
Grivna, S.T.1
Pyhtila, B.2
Lin, H.3
-
32
-
-
78049232764
-
Aberrant silencing of cancer-related genes by CpG hypermethylation occurs independently of their spatial organization in the nucleus
-
Easwaran HP, Van Neste L, Cope L, Sen S, Mohammad HP, et al. (2010) Aberrant silencing of cancer-related genes by CpG hypermethylation occurs independently of their spatial organization in the nucleus. Cancer Res 70: 8015-8024.
-
(2010)
Cancer Res
, vol.70
, pp. 8015-8024
-
-
Easwaran, H.P.1
van Neste, L.2
Cope, L.3
Sen, S.4
Mohammad, H.P.5
-
33
-
-
34547765951
-
Action at a distance: epigenetic silencing of large chromosomal regions in carcinogenesis
-
Clark SJ, (2007) Action at a distance: epigenetic silencing of large chromosomal regions in carcinogenesis. Hum Mol Genet 16 Spec No 1: R88-95.
-
(2007)
Hum Mol Genet
, vol.16 Spec
-
-
Clark, S.J.1
-
34
-
-
66349118913
-
Rapid repetitive element-mediated expansion of piRNA clusters in mammalian evolution
-
Assis R, Kondrashov AS, (2009) Rapid repetitive element-mediated expansion of piRNA clusters in mammalian evolution. Proc Natl Acad Sci U S A 106: 7079-7082.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 7079-7082
-
-
Assis, R.1
Kondrashov, A.S.2
-
35
-
-
34250199035
-
The induction of H3K9 methylation by PIWIL4 at the p16Ink4a locus
-
Sugimoto K, Kage H, Aki N, Sano A, Kitagawa H, et al. (2007) The induction of H3K9 methylation by PIWIL4 at the p16Ink4a locus. Biochem Biophys Res Commun 359: 497-502.
-
(2007)
Biochem Biophys Res Commun
, vol.359
, pp. 497-502
-
-
Sugimoto, K.1
Kage, H.2
Aki, N.3
Sano, A.4
Kitagawa, H.5
-
36
-
-
77954661906
-
DNA hypomethylation in cancer cells
-
Ehrlich M, (2009) DNA hypomethylation in cancer cells. Epigenomics 1: 239-259.
-
(2009)
Epigenomics
, vol.1
, pp. 239-259
-
-
Ehrlich, M.1
-
37
-
-
79959853446
-
Dissecting DNA hypermethylation in cancer
-
Estecio MR, Issa JP, (2011) Dissecting DNA hypermethylation in cancer. FEBS Lett 585: 2078-2086.
-
(2011)
FEBS Lett
, vol.585
, pp. 2078-2086
-
-
Estecio, M.R.1
Issa, J.P.2
|