Characterization and comparison of the properties of sarcoma cell lines in vitro and in vivo

Human Cell

Volumn 22, Issue 4, 2009, Pages 85-93

  Mills, Joslyn ^a   Matos, Tulio ^a   Charytonowicz, Elizabeth ^a   Hricik, Todd ^a   Castillo Martin, Mireia ^a   Remotti, Fabrizio ^a   Lee, Francis Y ^a   Matushansky, Igor ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Cell line; Properties; Sarcoma

Indexed keywords

KI 67 ANTIGEN; PROTEIN KINASE B; PROTEIN P53;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INVASION; CARCINOGENICITY; CONTROLLED STUDY; FUNCTIONAL GENOMICS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SARCOMA CELL; SCID MOUSE; TUMOR CELL LINE; TUMOR XENOGRAFT;

ANIMALS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; KI-67 ANTIGEN; MICE; MICE, INBRED NOD; MICE, SCID; NEOPLASM INVASIVENESS; NEOPLASM TRANSPLANTATION; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SARCOMA; TRANSPLANTATION, HETEROLOGOUS; TUMOR SUPPRESSOR PROTEIN P53;

MUS;

EID: 70350489124     PISSN: 09147470     EISSN: 17490774     Source Type: Journal    
DOI: 10.1111/j.1749-0774.2009.00073.x     Document Type: Article

References (20)

1. Li WW, Takahashi N, Jhanwar S et al. Sensitivity of soft tissue sarcoma cell lines to chemotherapeutic agents: identification of ecteinascidin-743 as a potent cytotoxic agent. Clin Cancer Res 2001 7 : 2908 2911.
2. Leu KM, Ostruszka LJ, Shewach D et al. Laboratory and clinical evidence of synergistic cytotoxicity of sequential treatment with gemcitabine followed by docetaxel in the treatment of sarcoma. J Clin Oncol 2004 22 : 1706 1712.
3. Grosso F, Jones RL, Demetri GD et al. Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: a retrospective study. Lancet Oncol 2007 8 : 595 602.
4. Maki RG, Wathen JK, Patel SR et al. Randomized phase II study of gemcitabine and docetaxel compared with gemcitabine alone in patients with metastatic soft tissue sarcomas: results of sarcoma alliance for research through collaboration study 002 corrected. J Clin Oncol 2007 25 : 2755 2763.
5. Maki RG. Gemcitabine and docetaxel in metastatic sarcoma: past, present, and future. Oncologist 2007 12 : 999 1006.
6. Matushansky I, Maki RG. Mechanisms of sarcomagenesis. Hematol Oncol Clin North Am 2005 19 : 427 449, v.
7. Verweij J, Casali PG, Zalcberg J et al. Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial. Lancet 2004 364 : 1127 1134.
8. Ando T, Ichikawa J, Okamoto A, Tasaka K, Nakao A, Hamada Y. Gemcitabine inhibits viability, growth, and metastasis of osteosarcoma cell lines. J Orthop Res 2005 23 : 964 969.
9. Graat HC, Witlox MA, Schagen FH et al. Different susceptibility of osteosarcoma cell lines and primary cells to treatment with oncolytic adenovirus and doxorubicin or cisplatin. Br J Cancer 2006 94 : 1837 1844.
10. Walters DK, Muff R, Langsam B, Gruber P, Born W, Fuchs B. Taurolidine: a novel anti-neoplastic agent induces apoptosis of osteosarcoma cell lines. Investig New Drugs 2007 25 : 305 312.
11. Moneo V, Serelde BG, Fominaya J et al. Extreme sensitivity to Yondelis (Trabectedin, ET-743) in low passaged sarcoma cell lines correlates with mutated p53. J Cell Biochem 2007 100 : 339 348.
12. Matushansky I, Hernando E, Socci ND et al. Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway. J Clin Invest 2007 117 : 3248 3257.
13. Chambers JM. Linear models. In : Chambers SJM, Hastie TJ, eds. Statistical Models. Pacific Grove, California : Wadsworth & Brooks/Cole, 1992 96 138.
14. Hastie TJ, Pregibon D. Generalized linear models. In : Chambers SJM, Hastie TJ, eds. Statistical Models. Pacific Grove, California : Wadsworth & Brooks/Cole, 1992 196 246.
15. Wilkinson GN, Rogers CE. Symbolic descriptions of factorial models for analysis of variance. Appl Stat 1973 22 : 392 399.
16. Heslin MJ, Cordon-Cardo C, Lewis JJ, Woodruff JM, Brennan MF. Ki-67 detected by MIB-1 predicts distant metastasis and tumor mortality in primary, high grade extremity soft tissue sarcoma. Cancer 1998 83 : 490 497.
17. Leach FS, Tokino T, Meltzer P et al. p53 Mutation and MDM2 amplification in human soft tissue sarcomas. Cancer Res 1993 53 : 2231 2234.
18. Latres E, Drobnjak M, Pollack D et al. Chromosome 17 abnormalities and TP53 mutations in adult soft tissue sarcomas. Am J Pathol 1994 145 : 345 355. (Pubitemid 24245835)
19. Hernando E, Charytonowicz E, Dudas ME et al. The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas. Nature Med 2007 13 : 748 753.
20. Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000 100 : 57 70.