The induction of H3K9 methylation by PIWIL4 at the p16Ink4a locus

Biochemical and Biophysical Research Communications

Volumn 359, Issue 3, 2007, Pages 497-502

  Sugimoto, Keiki ^a   Kage, Hidenori ^a   Aki, Naomi ^a   Sano, Atsushi ^a   Kitagawa, Hiroshi ^a   Nagase, Takahide ^a   Yatomi, Yutaka ^a   Ohishi, Nobuya ^a   Takai, Daiya ^a  

^a UNIVERSITY OF TOKYO HOSPITAL   (Japan)

Author keywords

Epigenetics; Histone methylation; p16Ink4a; PIWI

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 2A; HISTONE H3; HYBRID PROTEIN; LYSINE; PIWI LIKE 4 PROTEIN; PROTEIN; PROTEIN P16INK4A; UNCLASSIFIED DRUG;

ARTICLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; HUMAN; HUMAN CELL; METHYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SOMATIC CELL; TRANSIENT TRANSFECTION;

CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P16; GENE EXPRESSION REGULATION; HISTONES; HUMANS; LYSINE; METHYLATION; PROTEINS;

EID: 34250199035     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.05.136     Document Type: Article

References (27)

1. Issa J.P. CpG-island methylation in aging and cancer. Curr. Top. Microbiol. Immunol. 249 (2000) 101-118
2. Jones P.A., and Baylin S.B. The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3 (2002) 415-428
3. Klose R.J., and Bird A.P. Genomic DNA methylation: the mark and its mediators. Trends Biochem. Sci. 31 (2006) 89-97
4. Ting A.H., Schuebel K.E., Herman J.G., and Baylin S.B. Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation. Nat. Genet. 37 (2005) 906-910
5. Tahbaz N., Kolb F.A., Zhang H., Jaronczyk K., Filipowicz W., and Hobman T.C. Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer. EMBO Rep. 5 (2004) 189-194
6. Janowski B.A., Huffman K.E., Schwartz J.C., Ram R., Nordsell R., Shames D.S., Minna J.D., and Corey D.R. Involvement of AGO1 and AGO2 in mammalian transcriptional silencing. Nat. Struct. Mol. Biol. 13 (2006) 787-792
7. Kim D.H., Villeneuve L.M., Morris K.V., and Rossi J.J. Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells. Nat. Struct. Mol. Biol. 13 (2006) 793-797
8. Doi N., Zenno S., Ueda R., Ohki-Hamazaki H., Ui-Tei K., and Saigo K. Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors. Curr. Biol. 13 (2003) 41-46
9. Liu J., Carmell M.A., Rivas F.V., Marsden C.G., Thomson J.M., Song J.J., Hammond S.M., Joshua-Tor L., and Hannon G.J. Argonaute2 is the catalytic engine of mammalian RNAi. Science 305 (2004) 1437-1441
10. Cox D.N., Chao A., Baker J., Chang L., Qiao D., and Lin H. A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal. Genes Dev. 12 (1998) 3715-3727
11. Lin H., and Spradling A.C. A novel group of pumilio mutations affects the asymmetric division of germline stem cells in the Drosophila ovary. Development 124 (1997) 2463-2476
12. Vagin V.V., Sigova A., Li C., Seitz H., Gvozdev V., and Zamore P.D. A distinct small RNA pathway silences selfish genetic elements in the germline. Science 313 (2006) 320-324
13. Aravin A., Gaidatzis D., Pfeffer S., Lagos-Quintana M., Landgraf P., Iovino N., Morris P., Brownstein M.J., Kuramochi-Miyagawa S., Nakano T., Chien M., Russo J.J., Ju J., Sheridan R., Sander C., Zavolan M., and Tuschl T. A novel class of small RNAs bind to MILI protein in mouse testes. Nature 442 (2006) 203-207
14. Girard A., Sachidanandam R., Hannon G.J., and Carmell M.A. A germline-specific class of small RNAs binds mammalian Piwi proteins. Nature 442 (2006) 199-202
15. Grivna S.T., Beyret E., Wang Z., and Lin H. A novel class of small RNAs in mouse spermatogenic cells. Genes Dev. 20 (2006) 1709-1714
16. Lau N.C., Seto A.G., Kim J., Kuramochi-Miyagawa S., Nakano T., Bartel D.P., and Kingston R.E. Characterization of the piRNA complex from rat testes. Science 313 (2006) 363-367
17. Qiao D., Zeeman A.M., Deng W., Looijenga L.H., and Lin H. Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas. Oncogene 21 (2002) 3988-3999
18. Sasaki T., Shiohama A., Minoshima S., and Shimizu N. Identification of eight members of the Argonaute family in the human genome small star, filled. Genomics 82 (2003) 323-330
19. Reik W., Dean W., and Walter J. Epigenetic reprogramming in mammalian development. Science 293 (2001) 1089-1093
20. Nair R., Carter P., and Rost B. NLSdb: database of nuclear localization signals. Nucleic Acids Res. 31 (2003) 397-399
21. Kutay U., and Guttinger S. Leucine-rich nuclear-export signals: born to be weak. Trends Cell Biol. 15 (2005) 121-124
22. Liu J., Valencia-Sanchez M.A., Hannon G.J., and Parker R. MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nat. Cell Biol. 7 (2005) 719-723
23. Sen G.L., and Blau H.M. Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies. Nat. Cell Biol. 7 (2005) 633-636
24. Gil J., and Peters G. Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all. Nat. Rev. Mol. Cell Biol. 7 (2006) 667-677
25. Schmid C.W. Does SINE evolution preclude Alu function?. Nucleic Acids Res. 26 (1998) 4541-4550
26. Sano A., Kage H., Sugimoto K., Kitagawa H., Aki N., Goto A., Fukayama M., Nakajima J., Takamoto S., Nagase T., Yatomi Y., Ohishi N., and Takai D. A second-generation profiling system for quantitative methylation analysis of multiple gene promoters: application to lung cancer. Oncogene (2007)
27. Carmell M.A., Girard A., van de Kant H.J., Bourc'his D., Bestor T.H., de Rooij D.G., and Hannon G.J. MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline. Dev. Cell 12 (2007) 503-514