Secretion of IL-1β triggered by dynasore in murine peritoneal macrophages

Innate Immunity

Volumn 18, Issue 2, 2012, Pages 241-249

  Seil, Michèle ^a   El Ouaaliti, Malika ^a   Dehaye, Jean Paul ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

inflammasome; interleukin 1 ; ivermectin; P2X 7 KO mice; Purinergic receptors

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIPARASITIC AGENT; CALCIUM; DYNAMIN; DYNASORE; GUANOSINE TRIPHOSPHATASE; INTERLEUKIN 1BETA; IVERMECTIN; POTASSIUM; PURINERGIC P2X4 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; CELL VIABILITY; CYTOKINE RELEASE; DRUG POTENTIATION; ENZYME INHIBITION; INTERNALIZATION; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PROTEIN LOCALIZATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; CASPASE 1; CELLS, CULTURED; COLORING AGENTS; HYDRAZONES; INTERLEUKIN-1BETA; L-LACTATE DEHYDROGENASE; MACROPHAGES, PERITONEAL; MALE; MICE; MICE, KNOCKOUT; POTASSIUM; RECEPTORS, PURINERGIC P2X4; RECEPTORS, PURINERGIC P2X7; TETRAZOLIUM SALTS; THIAZOLES;

MURINAE; MUS;

EID: 84858378920     PISSN: 17534259     EISSN: 17534267     Source Type: Journal    
DOI: 10.1177/1753425911399478     Document Type: Article

References (36)

1. Surprenant A, North RA. Signaling at purinergic P2X receptors. Annu Rev Physiol. 2009 ; 71: 333-359
2. Roberts JA, Vial C, Digby HR, et al. Molecular properties of P2X receptors. Pflugers Arch. 2006 ; 452: 486-500 (Pubitemid 44015086)
3. Kim M, Jiang LH, Wilson HL, North RA, Surprenant A. Proteomic and functional evidence for a P2X7 receptor signalling complex. EMBO J. 2001 ; 20: 6347-6358 (Pubitemid 33078708)
4. Donnelly-Roberts DL, Namovic MT, Han P, Jarvis MF. Mammalian P2X7 receptor pharmacology: comparison of recombinant mouse, rat and human P2X7 receptors. Br J Pharmacol. 2009 ; 157: 1203-1214
5. Novak I, Jans IM, Wohlfahrt L. Effect of P2X7 receptor knockout on exocrine secretion of pancreas, salivary glands and lacrimal glands. J Physiol. 2010 ; 588: 3615-3627
6. North RA. Molecular physiology of P2X receptors. Physiol Rev. 2002 ; 82: 1013-1067
7. Dubyak GR. Go it alone no more-P2X7 joins the society of heteromeric ATP-gated receptor channels. Mol Pharmacol. 2007 ; 72: 1402-1405 (Pubitemid 350146076)
8. Qureshi OS, Paramasivam A, Yu JC, Murrell-Lagnado RD. Regulation of P2X4 receptors by lysosomal targeting, glycan protection and exocytosis. J Cell Sci. 2007 ; 120: 3838-3849 (Pubitemid 350187365)
9. Royle SJ, Bobanović LK, Murrell-Lagnado RD. Identification of a non-canonical tyrosine-based endocytic motif in an ionotropic receptor. J Biol Chem. 2002 ; 277: 35378-35385
10. Traub LM. Tickets to ride: selecting cargo for clathrin-regulated internalization. Nat Rev Mol Cell Biol. 2009 ; 10: 583-596
11. Mettlen M, Pucadyil T, Ramachandran R, Schmid SL. Dissecting dynamin's role in clathrin-mediated endocytosis. Biochem Soc Trans. 2009 ; 37: 1022-1026
12. Bobanovic LK, Royle SJ, Murrell-Lagnado RD. P2X receptor trafficking in neurons is subunit specific. J Neurosci. 2002 ; 22: 4814-4824 (Pubitemid 37465596)
13. Brown DA, Yule DI. Protein kinase A regulation of P2X4 receptors: requirement for a specific motif in the C-terminus. Biochim Biophys Acta. 2010 ; 1803: 275-287
14. Carroll RC, Beattie EC, Xia H, et al. Dynamin-dependent endocytosis of ionotropic glutamate receptors. Proc Natl Acad Sci USA. 1999 ; 96: 14112-14117
15. Macia E, Ehrlich M, Massol R, Boucrot E, Brunner C, Kirchhausen T. Dynasore, a cell permeable inhibitor of dynamin. Dev Cell. 2006 ; 10: 839-850 (Pubitemid 43779110)
16. Nankoe SR, Sever S. Dynasore puts a new spin on dynamin: a surprising dual role during vesicle formation. Trends Cell Biol. 2006 ; 16: 607-609 (Pubitemid 44809886)
17. Boumechache M, Masin M, Edwardson JM, Górecki DC, Murrell-Lagnado R. Analysis of assembly and trafficking of native P2X4 and P2X7 receptor complexes in rodent immune cells. J Biol Chem. 2009 ; 284: 13446-13454
18. Solle M, Labasi J, Perregaux G, et al. Altered cytokine production in mice lacking P2X7 receptors. J Biol Chem. 2001 ; 276: 125-132 (Pubitemid 32050297)
19. Seil M, Kabré E, Nagant C, et al. Regulation by CRAMP of the responses of murine peritoneal macrophages to extracellular ATP. Biochim Biophys Acta. 2010 ; 1798: 569-578
20. Pochet S, Garcia-Marcos M, Seil M, Otto A, Marino A, Dehaye JP. Contribution of two ionotropic purinergic receptors to ATP responses in submandibular gland ductal cells. Cell Signal. 2007 ; 19: 2155-2164 (Pubitemid 47353818)
21. McCarron RM, Goroff DK, Luhr JE, Murphy MA, Herscowitz HB. Methods for the collection of peritoneal and alveolar macrophages. Methods Enzymol. 1984 ; 108: 274-284 (Pubitemid 15215631)
22. Grynkiewicz G, Poenie M, Tsien RY. A new generation of calcium indicators with greatly improved fluorescence properties. J Biol Chem. 1985 ; 260: 3440-3450 (Pubitemid 15114340)
23. Denizot F, Lang R. Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J Immunol Methods. 1986 ; 89: 271-277 (Pubitemid 16080782)
24. Khakh BS, Proctor WR, Dunwiddie TV, Labarca C, Lester HA. Allosteric control of gating and kinetics at P2X4 receptor channels. J Neurosci. 1999 ; 19: 7289-7299 (Pubitemid 29404585)
25. Arlehamn CS, Pétrilli V, Gross O, Tschopp J, Evans TJ. The role of potassium in inflammasome activation by bacteria. J Biol Chem. 2010 ; 285: 10508-10518
26. Kawate T, Michel JC, Birdsong WT, Gouaux E. Crystal structure of the ATP-gated P2X4 ion channel in the closed state. Nature. 2009 ; 460: 592-598
27. Ulmann L, Hirbec H, Rassendren F. P2X4 receptors mediate PGE2 release by tissue-resident macrophages and initiate inflammatory pain. EMBO J. 2010 ; 29: 2290-2300
28. Seil M, El Ouaaliti M, Fontanils U, Gorronzo Extebarria I, Pochet S, Dal Moro G, Marino A, Dehaye J-P. Ivermectin-dependent release of IL-1beta in response to ATP by peritoneal macrophages from P2X7-KO mice. Purinergic Signal. 2011 ; 6: 405-416
29. Stokes L, Surprenant A. Dynamic regulation of the P2X4 receptor in alveolar macrophages by phagocytosis and classical activation. Eur J Immunol. 2009 ; 39: 986-995
30. Toulmé E, Soto F, Garret M, Boué-Grabot E. Functional properties of internalization-deficient P2X4 receptors reveal a novel mechanism of ligand-gated channel facilitation by ivermectin. Mol Pharmacol. 2006 ; 69: 576-587 (Pubitemid 43121955)
31. Asatryan L, Popova M, Perkins D, Trudell JR, Alkana RL, Davies DL. Ivermectin antagonizes ethanol inhibition in purinergic P2X4 receptors. J Pharmacol Exp Ther. 2010 ; 334: 720-728
32. Silberberg SD, Swartz KJ. Ivermectin interaction with transmembrane helices reveals widespread rearrangements during opening of P2X receptor channels. Neuron. 2007 ; 54: 263-274 (Pubitemid 46561201)
33. Marina-García N, Franchi L, Kim YG, et al. Clathrin- and dynamin-dependent endocytic pathway regulates muramyl dipeptide internalization and NOD2 activation. J Immunol. 2009 ; 182: 4321-4327
34. Stewart CR, Stuart LM, Wilkinson K, et al. CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer. Nat Immunol. 2010 ; 11: 155-161
35. Hibino H, Inanobe A, Furutani K, Murakami S, Findlay I, Kurachi Y. Inwardly rectifying potassium channels: their structure, function, and physiological roles. Physiol Rev. 2010 ; 90: 291-366
36. Chung CL, Sheu JR, Liu HE, et al. Dynasore, a dynamin inhibitor, induces PAI-1 expression in MeT-5A human pleural mesothelial cells. Am J Respir Cell Mol Biol. 2009 ; 40: 692-700