Competition between pentoses and glucose during uptake and catabolism in recombinant Saccharomyces cerevisiae

Biotechnology for Biofuels

Volumn 5, Issue , 2012, Pages

  Subtil, Thorsten ^a   Boles, Eckhard ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

Arabinose; Ethanol; Fermentation; Glucose; Hexokinase; Lignocellulose; Pentose; Saccharomyces; Xylose; Yeast

Indexed keywords

ARABINOSE; HEXOKINASES; LIGNOCELLULOSE; PENTOSE; SACCHAROMYCES;

ETHANOL; FERMENTATION; MALTOSE; METABOLISM; XYLOSE; YEAST;

GLUCOSE;

BIOLOGICAL UPTAKE; CATABOLISM; CELLULOSE; ENZYME ACTIVITY; ETHANOL; FERMENTATION; GLUCOSE; INHIBITION; YEAST;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 84858262547     PISSN: 17546834     EISSN: None     Source Type: Journal    
DOI: 10.1186/1754-6834-5-14     Document Type: Article

References (62)

1. Xylose Fermentation by Saccharomyces cerevisia. Kötter P, Ciriacy M, Appl Microbiol Biotechnol 1993 38 776 783 10.1007/BF00167144
2. Ethanol production from xylose by recombinant Saccharomyces cerevisia expressing protein-engineered NADH-preferring xylose reductase from Pichia stipiti. Watanabe S, Abu Saleh A, Pack SP, Annaluru N, Kodaki T, Makino K, Microbiology 2007 153 3044 3054 10.1099/mic.0.2007/007856-0 17768247 (Pubitemid 47517065)
3. Ethanol production from xylose by recombinant Saccharomyces cerevisia expressing protein engineered NADP + -dependent xylitol dehydrogenase. Watanabe S, Saleh AA, Pack SP, Annaluru N, Kodaki T, Makino K, J Biotechnol 2007 130 316 319 10.1016/j.jbiotec.2007.04.019 17555838 (Pubitemid 46920539)
4. Efficient bioethanol production from xylose by recombinant Saccharomyces cerevisia requires high activity of xylose reductase and moderate xylulokinase activity. Matsushika A, Sawayama S, J Biosci Bioeng 2008 106 306 309 10.1263/jbb.106.306 18930011
5. High-level functional expression of a fungal xylose isomerase: the key to efficient ethanolic fermentation of xylose by Saccharomyces cerevisia? Kuyper M, Harhangi HR, Stave AK, Winkler AA, Jetten MS, de Laat WT, den Ridder JJ, Op den Camp HJ, van Dijken JP, Pronk JT, FEMS Yeast Res 2003 4 69 78 10.1016/S1567-1356(03)00141-7 14554198 (Pubitemid 38367533)
6. Functional expression of a bacterial xylose isomerase in Saccharomyces cerevisia. Brat D, Boles E, Wiedemann B, Appl Environ Microbiol 2009 75 2304 2311 10.1128/AEM.02522-08 19218403
7. Xylose isomerase from polycentric fungus Orpinomyce: gene sequencing, cloning, and expression in Saccharomyces cerevisia for bioconversion of xylose to ethanol. Madhavan A, Tamalampudi S, Ushida K, Kanai D, Katahira S, Srivastava A, Fukuda H, Bisaria VS, Kondo A, Appl Microbiol Biotechnol 2009 82 1067 1078 10.1007/s00253-008-1794-6 19050860
8. Isolation of xylose isomerases by sequence- and function-based screening from a soil metagenomic library. Parachin NS, Gorwa-Grauslund MF, Biotechnol Biofuels 2011 4 9 10.1186/1754-6834-4-9 21545702
9. The missing link in the fungal L-arabinose catabolic pathway, identification of the L-xylulose reductase gene. Richard P, Putkonen M, Vaananen R, Londesborough J, Penttila M, Biochemistry 2002 41 6432 6437 10.1021/bi025529i 12009906 (Pubitemid 34526009)
10. A modified Saccharomyces cerevisia strain that consumes L-Arabinose and produces ethanol. Becker J, Boles E, Appl Environ Microbiol 2003 69 4144 4150 10.1128/AEM.69.7.4144-4150.2003 12839792 (Pubitemid 36873782)
11. Codon-optimized bacterial genes improve L-Arabinose fermentation in recombinant Saccharomyces cerevisia. Wiedemann B, Boles E, Appl Environ Microbiol 2008 74 2043 2050 10.1128/AEM.02395-07 18263741 (Pubitemid 351522057)
12. Characterization of the effectiveness of hexose transporters for transporting xylose during glucose and xylose co-fermentation by a recombinant Saccharomyce yeast. Sedlak M, Ho NW, Yeast 2004 21 671 684 10.1002/yea.1060 15197732 (Pubitemid 38868185)
13. Metabolic engineering of a xylose-isomerase-expressing Saccharomyces cerevisia strain for rapid anaerobic xylose fermentation. Kuyper M, Hartog MM, Toirkens MJ, Almering MJ, Winkler AA, van Dijken JP, Pronk JT, FEMS Yeast Res 2005 5 399 409 10.1016/j.femsyr.2004.09.010 15691745 (Pubitemid 40192529)
14. Characterization of the xylose-transporting properties of yeast hexose transporters and their influence on xylose utilization. Hamacher T, Becker J, Gardonyi M, Hahn-Hagerdal B, Boles E, Microbiology 2002 148 2783 2788 12213924
15. Comparison of heterologous xylose transporters in recombinant Saccharomyces cerevisia. Runquist D, Hahn-Hagerdal B, Radstrom P, Biotechnol Biofuels 2010 3 5 10.1186/1754-6834-3-5 20236521
16. Xylose transport studies with xylose-utilizing Saccharomyces cerevisia strains expressing heterologous and homologous permeases. Saloheimo A, Rauta J, Stasyk OV, Sibirny AA, Penttila M, Ruohonen L, Appl Microbiol Biotechnol 2007 74 1041 1052 10.1007/s00253-006-0747-1 17180689 (Pubitemid 46434755)
17. Expression of a heterologous xylose transporter in a Saccharomyces cerevisia strain engineered to utilize xylose improves aerobic xylose consumption. Hector RE, Qureshi N, Hughes SR, Cotta MA, Appl Microbiol Biotechnol 2008 80 675 684 10.1007/s00253-008-1583-2 18629494
18. Two glucose/xylose transporter genes from the yeast Candida intermedi: first molecular characterization of a yeast xylose-H + symporter. Leandro MJ, Goncalves P, Spencer-Martins I, Biochem J 2006 395 543 549 10.1042/BJ20051465 16402921
19. Improvement of ethanol productivity during xylose and glucose co-fermentation by xylose-assimilating S. cerevisia via expression of glucose transporter Sut1. Katahira S, Ito M, Takema H, Fujita Y, Tanino T, Tanaka T, Fukuda H, Kondo A, Enzyme Microb Technol 2008 43 115 119 10.1016/j.enzmictec. 2008.03.001
20. Discovery and characterization of novel D-xylose-specific transporters from Neurospora crass and Pichia stipiti. Du J, Li S, Zhao H, Mol Biosyst 2010 6 2150 2156 10.1039/c0mb00007h 20714641
21. Improving L-arabinose utilization of pentose fermenting Saccharomyces cerevisia cells by heterologous expression of L-arabinose transporting sugar transporters. Subtil T, Boles E, Biotechnol Biofuels 2011 4 38 10.1186/1754-6834-4-38 21992610
22. Galactose transport in Saccharomyces cerevisia. II. Characteristics of galactose uptake and exchange in galactokinaseless cells. Kou SC, Christensen MS, Cirillo VP, J Bacteriol 1970 103 671 678 5474882
23. Isolation and Characterization of a Maltose Transport Mutant in the Yeast Saccharomyces cerevisia. Goldenthal MJ, Cohen JD, Marmur J, Curr Genet 1983 7 195 199 10.1007/BF00434890
24. Structure of the multigene family of MAL loci in Saccharomyce. Chow TH, Sollitti P, Marmur J, Mol Gen Genet 1989 217 60 69 10.1007/BF00330943 2549370 (Pubitemid 19155283)
25. Molecular and industrial aspects of glucose isomerase. Bhosale SH, Rao MB, Deshpande VV, Microbiol Rev 1996 60 280 300 8801434 (Pubitemid 26170908)
26. Hxt-carrier-mediated glucose efflux upon exposure of Saccharomyces cerevisia to excess maltose. Jansen ML, De Winde JH, Pronk JT, Appl Environ Microbiol 2002 68 4259 4265 10.1128/AEM.68.9.4259-4265.2002 12200274 (Pubitemid 34988104)
27. High-affinity glucose uptake in Saccharomycs cerevisiae is not dependent on the presence of glucose-phosphorylating enzymes. Smits HP, Smits GJ, Postma PW, Walsh MC, van Dam K, Yeast 1996 12 439 447 10.1002/(SICI)1097-0061(199604) 12:5<439::AID-YEA925>3.0.CO;2-W 8740417 (Pubitemid 26157850)
28. Functional studies of yeast glucokinase. Clifton D, Walsh RB, Fraenkel DG, J Bacteriol 1993 175 3289 3294 8501032 (Pubitemid 23163370)
29. Yeast hexokinase mutants. Gancedo JM, Clifton D, Fraenkel DG, J Biol Chem 1977 252 4443 4444 326775 (Pubitemid 8155958)
30. Physiological role of glucose-phosphorylating enzymes in Saccharomyces cerevisia. Lobo Z, Maitra PK, Arch Biochem Biophys 1977 182 639 645 10.1016/0003-9861(77)90544-6 332086 (Pubitemid 8161072)
31. Transcriptional regulation of the Saccharomyces cerevisia HXK1, HXK2 and GLK1 genes. Herrero P, Galindez J, Ruiz N, Martinez-Campa C, Moreno F, Yeast 1995 11 137 144 10.1002/yea.320110205 7732723
32. A new efficient gene disruption cassette for repeated use in budding yeast. Guldener U, Heck S, Fielder T, Beinhauer J, Hegemann JH, Nucleic Acids Res 1996 24 2519 2524 10.1093/nar/24.13.2519 8692690 (Pubitemid 26237149)
33. Structure and function of enzymes of the Leloir pathway for galactose metabolism. Holden HM, Rayment I, Thoden JB, J Biol Chem 2003 278 43885 43888 10.1074/jbc.R300025200 12923184 (Pubitemid 37377125)
34. Kinetic characterization of individual hexose transporters of Saccharomyces cerevisia and their relation to the triggering mechanisms of glucose repression. Reifenberger E, Boles E, Ciriacy M, Eur J Biochem 1997 245 324 333 10.1111/j.1432-1033.1997.00324.x 9151960 (Pubitemid 27171254)
35. Metabolism of 2-deoxy-D glucose by Baker's yeast. IV. Incorporation of 2-deoxy-D-glucose into cell wall mannan. Biely P, Kratky Z, Bauer S, Biochim Biophys Acta 1972 255 631 639 10.1016/0005-2736(72)90166-6 4550701
36. Metabolic Studies with 2-Deoxyhexoses.2. Mechanisms of Inhibition of Growth + Fermentation in Bakers Yeast. Heredia CF, Delafuente G, Sols A, Biochimica Et Biophysica Acta 1964 86 216 223 10.1016/0304-4165(64)90045-5 14167419
37. Molecular characterization of a gene that confers 2-deoxyglucose resistance in yeast. Sanz P, Randez-Gil F, Prieto JA, Yeast 1994 10 1195 1202 10.1002/yea.320100907 7754708 (Pubitemid 24290795)
38. Evolutionary engineering of mixed-sugar utilization by a xylose-fermenting Saccharomyces cerevisia strain. Kuyper M, Toirkens MJ, Diderich JA, Winkler AA, van Dijken JP, Pronk JT, FEMS Yeast Res 2005 5 925 934 10.1016/j.femsyr.2005.04.004 15949975 (Pubitemid 40941017)
39. Fermentation of mixed glucose-xylose substrates by engineered strains of Saccharomyces cerevisia: role of the coenzyme specificity of xylose reductase, and effect of glucose on xylose utilization. Krahulec S, Petschacher B, Wallner M, Longus K, Klimacek M, Nidetzky B, Microb Cell Fact 2010 9 16 10.1186/1475-2859-9-16 20219100
40. Alcoholic fermentation of xylose and mixed sugars using recombinant Saccharomyces cerevisia engineered for xylose utilization. Madhavan A, Tamalampudi S, Srivastava A, Fukuda H, Bisaria V, Kondo A, Appl Microbiol Biotechnol 2009 82 1037 1047 10.1007/s00253-008-1818-2 19125247
41. Fungal BLAST and Model Organism BLASTP Best Hits: new comparison resources at the Saccharomyce Genome Database (SGD). Balakrishnan R, Christie KR, Costanzo MC, Dolinski K, Dwight SS, Engel SR, Fisk DG, Hirschman JE, Hong EL, Nash R, et al. Nucleic Acids Res 2005 33 374 D377 15608219
42. Global analysis of protein expression in yeast. Ghaemmaghami S, Huh WK, Bower K, Howson RW, Belle A, Dephoure N, O'Shea EK, Weissman JS, Nature 2003 425 737 741 10.1038/nature02046 14562106 (Pubitemid 37314318)
43. Conditions with high intracellular glucose inhibit sensing through glucose sensor Snf3 in Saccharomyces cerevisia. Karhumaa K, Wu B, Kielland-Brandt MC, J Cell Biochem 2010 110 920 925 10.1002/jcb.22605 20564191
44. Catabolite inactivation of the galactose transporter in the yeast Saccharomyces cerevisia: ubiquitination, endocytosis, and degradation in the vacuole. Horak J, Wolf DH, J Bacteriol 1997 179 1541 1549 9045811 (Pubitemid 27100440)
45. Selective uptake of cytosolic, peroxisomal, and plasma membrane proteins into the yeast lysosome for degradation. Chiang HL, Schekman R, Hamamoto S, J Biol Chem 1996 271 9934 9941 10.1074/jbc.271.17.9934 8626630 (Pubitemid 26131546)
46. Inactivation of the galactose transport system in Saccharomyces cerevisia. DeJuan C, Lagunas R, FEBS Lett 1986 207 258 261 10.1016/0014-5793(86) 81500-9 3533630 (Pubitemid 17176187)
47. The HTR1 gene is a dominant negative mutant allele of MTH1 and blocks Snf3- and Rgt2-dependent glucose signaling in yeast. Schulte F, Wieczorke R, Hollenberg CP, Boles E, J Bacteriol 2000 182 540 542 10.1128/JB.182.2.540-542. 2000 10629208 (Pubitemid 30030146)
48. Function and regulation of yeast hexose transporters. zcan S, Johnston M, Microbiol Mol Biol Rev 1999 63 554 569 10477308 (Pubitemid 29422782)
49. Metabolic flux analysis of xylose metabolism in recombinant Saccharomyces cerevisia using continuous culture. Pitkänen JP, Aristidou A, Salusjarvi L, Ruohonen L, Penttila M, Metab Eng 2003 5 16 31 10.1016/S1096-7176(02)00012-5 12749841 (Pubitemid 36599677)
50. Prefermentation improves xylose utilization in simultaneous saccharification and co-fermentation of pretreated spruce. Bertilsson M, Olofsson K, Liden G, Biotechnol Biofuels 2009 2 8 10.1186/1754-6834-2-8 19356227
51. Improving simultaneous saccharification and co-fermentation of pretreated wheat straw using both enzyme and substrate feeding. Olofsson K, Palmqvist B, Liden G, Biotechnology for Biofuels 2010 3 17 20678195
52. Role of xylose transporters in xylitol production from engineered Escherichia col. Khankal R, Chin JW, Cirino PC, J Biotechnol 2008 134 246 252 10.1016/j.jbiotec.2008.02.003 18359531
53. Engineering Escherichia col for xylitol production from glucose-xylose mixtures. Cirino PC, Chin JW, Ingram LO, Biotechnol Bioeng 2006 95 1167 1176 10.1002/bit.21082 16838379 (Pubitemid 44901332)
54. Engineered Saccharomyces cerevisia capable of simultaneous cellobiose and xylose fermentation. Ha SJ, Galazka JM, Kim SR, Choi JH, Yang X, Seo JH, Glass NL, Cate JH, Jin YS, Proc Natl Acad Sci USA 2011 108 504 509 10.1073/pnas.1010456108 21187422
55. Evolutionary engineering of industrially important microbial phenotypes. Sauer U, Adv Biochem Eng Biotechnol 2001 73 129 169 11816810
56. Procedures used in the induction of mitotic recombination and mutation in the yeast Saccharomyces cerevisia. Zimmermann FK, Mutat Res 1975 31 71 86 235086
57. High efficiency transformation of E. col by high voltage electroporation. Dower WJ, Miller JF, Ragsdale CW, Nucleic Acids Res 1988 16 6127 6145 10.1093/nar/16.13.6127 3041370
58. Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method. Gietz RD, Woods RA, Methods Enzymol 2002 350 87 96 12073338 (Pubitemid 34619485)
59. Frozen competent yeast cells that can be transformed with high efficiency using the LiAc/SS carrier DNA/PEG method. Gietz RD, Schiestl RH, Nat Protoc 2007 2 1 4 17401330 (Pubitemid 47040061)
60. Molecular cloning. A laboratory manua. Sambrook J, Russell DW, New York: Cold Spring Harbor 2001
61. Catabolite inactivation of the high-affinity hexose transporters Hxt6 and Hxt7 of Saccharomyces cerevisia occurs in the vacuole after internalization by endocytosis. Krampe S, Stamm O, Hollenberg CP, Boles E, FEBS Lett 1998 441 343 347 10.1016/S0014-5793(98)01583-X 9891967 (Pubitemid 29065311)
62. A novel signal transduction pathway in Saccharomyces cerevisia defined by Snf3-regulated expression of HXT. Liang H, Gaber RF, Mol Biol Cell 1996 7 1953 1966 8970157 (Pubitemid 26415002)