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Volumn 10, Issue 3, 2012, Pages 299-305

Can an immune-regulatory vaccine prevent HIV infection?

Author keywords

HIV; immune regulation; T cells; vaccine

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS VACCINE; RECOMBINANT INTERLEUKIN 10;

EID: 84858215945     PISSN: 14787210     EISSN: 17448336     Source Type: Journal    
DOI: 10.1586/eri.11.178     Document Type: Review
Times cited : (6)

References (62)
  • 1
    • 41149096579 scopus 로고    scopus 로고
    • T-cell quality in memory and protection: Implications for vaccine design
    • DOI 10.1038/nri2274, PII NRI2274
    • Seder RA, Darrah PA, Roederer M. T-cell quality in memory and protection: implications for vaccine design. Nat. Rev. Immunol. 8(4), 247-258 (2008). (Pubitemid 351432801)
    • (2008) Nature Reviews Immunology , vol.8 , Issue.4 , pp. 247-258
    • Seder, R.A.1    Darrah, P.A.2    Roederer, M.3
  • 2
    • 50449090525 scopus 로고    scopus 로고
    • An HIV vaccine -challenges and prospects
    • Johnston MI, Fauci AS. An HIV vaccine -challenges and prospects. N. Engl. J. Med. 359(9), 888-890 (2008).
    • (2008) N. Engl. J. Med. , vol.359 , Issue.9 , pp. 888-890
    • Johnston, M.I.1    Fauci, A.S.2
  • 3
    • 69149083668 scopus 로고    scopus 로고
    • Neutralizing antibodies generated during natural HIV-1 infection: Good news for an HIV-1 vaccine?
    • Stamatatos L, Morris L, Burton DR, Mascola JR. Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine? Nat. Med. 15(8), 866-870 (2009).
    • (2009) Nat Med. , vol.15 , Issue.8 , pp. 866-870
    • Stamatatos, L.1    Morris, L.2    Burton, D.R.3    Mascola, J.R.4
  • 4
    • 77953543379 scopus 로고    scopus 로고
    • Rational antibody-based HIV-1 vaccine design: Current approaches and future directions
    • Walker LM, Burton DR. Rational antibody-based HIV-1 vaccine design: current approaches and future directions. Curr. Opin. Immunol. 22(3), 358-366 (2010).
    • (2010) Curr. Opin. Immunol. , vol.22 , Issue.3 , pp. 358-366
    • Walker, L.M.1    Burton, D.R.2
  • 5
    • 56649105122 scopus 로고    scopus 로고
    • Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the step study): A double-blind, randomised, placebo-controlled, test-of-concept trial
    • Buchbinder SP, Mehrotra DV, Duerr A et al. Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the step study): a double-blind, randomised, placebo-controlled, test-of-concept trial. Lancet 372(9653), 1881-1893 (2008).
    • (2008) Lancet , vol.372 , Issue.9653 , pp. 1881-1893
    • Buchbinder, S.P.1    Mehrotra, D.V.2    Duerr, A.3
  • 6
    • 35748968205 scopus 로고    scopus 로고
    • HIV vaccine failure prompts Merck to halt trial
    • HIV vaccine failure prompts Merck to halt trial. Nature 449 (2007).
    • (2007) Nature , vol.449
  • 7
    • 73349094086 scopus 로고    scopus 로고
    • Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand
    • Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S et al. Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N. Engl. J. Med. 361(23), 2209-2220 (2009).
    • (2009) N. Engl. J. Med. , vol.361 , Issue.23 , pp. 2209-2220
    • Rerks-Ngarm, S.1    Pitisuttithum, P.2    Nitayaphan, S.3
  • 9
    • 79951816846 scopus 로고    scopus 로고
    • A DNA vaccine encoding multiple HIV CD4 epitopes elicits vigorous polyfunctional, long-lived CD4+ and CD8+ T cell responses
    • Rosa DS, Ribeiro SP, Almeida RR et al. A DNA vaccine encoding multiple HIV CD4 epitopes elicits vigorous polyfunctional, long-lived CD4+ and CD8+ T cell responses. PLoS One 6(2), e16921 (2011).
    • (2011) PLoS One , vol.6 , Issue.2
    • Rosa, D.S.1    Ribeiro, S.P.2    Almeida, R.R.3
  • 13
    • 0037105617 scopus 로고    scopus 로고
    • CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load
    • Sousa AE, Carneiro J, Meier-Schellersheim M, Grossman Z, Victorino RM. CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load. J. Immunol. 169(6), 3400-3406 (2002). (Pubitemid 35013190)
    • (2002) Journal of Immunology , vol.169 , Issue.6 , pp. 3400-3406
    • Sousa, A.E.1    Carneiro, J.2    Meier-Schellersheim, M.3    Grossman, Z.4    Victorino, R.M.M.5
  • 14
    • 67650655984 scopus 로고    scopus 로고
    • Interleukin-10 promoter polymorphisms influence HIV-1 susceptibility and primary HIV-1 pathogenesis
    • Naicker DD, Werner L, Kormuth E et al. Interleukin-10 promoter polymorphisms influence HIV-1 susceptibility and primary HIV-1 pathogenesis. J. Infect. Dis. 200(3), 448-452 (2009).
    • (2009) J. Infect. Dis. , vol.200 , Issue.3 , pp. 448-452
    • Naicker, D.D.1    Werner, L.2    Kormuth, E.3
  • 16
    • 79957618772 scopus 로고    scopus 로고
    • Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine
    • Hansen SG, Ford JC, Lewis MS et al. Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine. Nature 473(7348), 523-527 (2011).
    • (2011) Nature , vol.473 , Issue.7348 , pp. 523-527
    • Hansen, S.G.1    Ford, J.C.2    Lewis, M.S.3
  • 17
    • 67449101823 scopus 로고    scopus 로고
    • Vaccine-induced cellular responses control simian immunodeficiency virus replication after heterologous challenge
    • Wilson NA, Keele BF, Reed JS et al. Vaccine-induced cellular responses control simian immunodeficiency virus replication after heterologous challenge. J. Virol. 83(13), 6508-6521 (2009).
    • (2009) J. Virol. , vol.83 , Issue.13 , pp. 6508-6521
    • Wilson, N.A.1    Keele, B.F.2    Reed, J.S.3
  • 18
    • 64949118709 scopus 로고    scopus 로고
    • Passive immunization with human neutralizing monoclonal antibodies against HIV-1 in macaque models: Experimental approaches
    • xiv
    • Ruprecht RM. Passive immunization with human neutralizing monoclonal antibodies against HIV-1 in macaque models: experimental approaches. Methods Mol. Biol. 525, 559-566, xiv (2009).
    • (2009) Methods Mol. Biol. , vol.525 , pp. 559-566
    • Ruprecht, R.M.1
  • 19
    • 56649114351 scopus 로고    scopus 로고
    • HIV-1 vaccine-induced immunity in the test-of-concept Step Study: A case-cohort analysis
    • McElrath MJ, De Rosa SC, Moodie Z et al. HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis. Lancet 372(9653), 1894-1905 (2008).
    • (2008) Lancet , vol.372 , Issue.9653 , pp. 1894-1905
    • McElrath, M.J.1    De Rosa, S.C.2    Moodie, Z.3
  • 20
    • 79952335046 scopus 로고    scopus 로고
    • Plasma levels of soluble CD14 independently predict mortality in HIV infection
    • Sandler NG, Wand H, Roque A et al. Plasma levels of soluble CD14 independently predict mortality in HIV infection. J. Infect. Dis. 203(6), 780-790 (2011).
    • (2011) J. Infect. Dis. , vol.203 , Issue.6 , pp. 780-790
    • Sandler, N.G.1    Wand, H.2    Roque, A.3
  • 21
    • 35748939690 scopus 로고    scopus 로고
    • HIV disease progression: Immune activation, microbes, and a leaky gut
    • Douek D. HIV disease progression: immune activation, microbes, and a leaky gut. Top HIV Med. 15(4), 114-117 (2007).
    • (2007) Top HIV Med. , vol.15 , Issue.4 , pp. 114-117
    • Douek, D.1
  • 22
    • 77952742298 scopus 로고    scopus 로고
    • Effects of thymic selection of the T-cell repertoire on HLA Class 1-associated control of HIV infection
    • Kosmrlj A, Read EL, Qi Y et al. Effects of thymic selection of the T-cell repertoire on HLA Class 1-associated control of HIV infection. Nature 465(7296), 350-354 (2010).
    • (2010) Nature , vol.465 , Issue.7296 , pp. 350-354
    • Kosmrlj, A.1    Read, E.L.2    Qi, Y.3
  • 23
    • 33645057209 scopus 로고    scopus 로고
    • Suppressed cellular alloimmune responses in HIV-exposed seronegative female sex workers
    • Jennes W, Evertse D, Borget MY et al. Suppressed cellular alloimmune responses in HIV-exposed seronegative female sex workers. Clin. Exp. Immunol. 143(3), 435-444 (2006).
    • (2006) Clin. Exp. Immunol. , vol.143 , Issue.3 , pp. 435-444
    • Jennes, W.1    Evertse, D.2    Borget, M.Y.3
  • 25
    • 65649106139 scopus 로고    scopus 로고
    • Decreased immune activation in resistance to HIV-1 infection is associated with an elevated frequency of CD4(+)CD25(+)FOXP3(+) regulatory T cells
    • Card CM, McLaren PJ, Wachihi C, Kimani J, Plummer FA, Fowke KR. Decreased immune activation in resistance to HIV-1 infection is associated with an elevated frequency of CD4(+)CD25(+)FOXP3(+) regulatory T cells. J. Infect. Dis. 199(9), 1318-1322 (2009).
    • (2009) J. Infect. Dis. , vol.199 , Issue.9 , pp. 1318-1322
    • Card, C.M.1    McLaren, P.J.2    Wachihi, C.3    Kimani, J.4    Plummer, F.A.5    Fowke, K.R.6
  • 26
    • 78049448608 scopus 로고    scopus 로고
    • HIV-exposed seronegative commercial sex workers show a quiescent phenotype in the CD4+ T cell compartment and reduced expression of HIV-dependent host factors
    • McLaren PJ, Ball TB, Wachihi C et al. HIV-exposed seronegative commercial sex workers show a quiescent phenotype in the CD4+ T cell compartment and reduced expression of HIV-dependent host factors. J. Infect. Dis. 202(Suppl. 3), S339-S344 (2010).
    • (2010) J. Infect. Dis. , vol.202 , Issue.SUPPL. 3
    • McLaren, P.J.1    Ball, T.B.2    Wachihi, C.3
  • 27
    • 33746583527 scopus 로고    scopus 로고
    • Reduced CD4 T cell activation and in vitro susceptibility to HIV-1 infection in exposed uninfected Central Africans
    • Begaud E, Chartier L, Marechal V et al. Reduced CD4 T cell activation and in vitro susceptibility to HIV-1 infection in exposed uninfected Central Africans. Retrovirology 3, 35 (2006).
    • (2006) Retrovirology , vol.3 , pp. 35
    • Begaud, E.1    Chartier, L.2    Marechal, V.3
  • 29
    • 84555206609 scopus 로고    scopus 로고
    • Association of IL-10-promoter genetic variants with the rate of CD4 T-cell loss, IL-10 plasma levels, and breadth of cytotoxic T-cell lymphocyte response during chronic HIV-1 infection
    • Naicker DD, Wang B, Losina E et al. Association of IL-10-promoter genetic variants with the rate of CD4 T-cell loss, IL-10 plasma levels, and breadth of cytotoxic T-cell lymphocyte response during chronic HIV-1 infection. Clin. Infect. Dis. 54(2), 294-302 (2011).
    • (2011) Clin. Infect. Dis. , vol.54 , Issue.2 , pp. 294-302
    • Naicker, D.D.1    Wang, B.2    Losina, E.3
  • 32
    • 67349101763 scopus 로고    scopus 로고
    • Glycerol monolaurate prevents mucosal SIV transmission
    • Li Q, Estes JD, Schlievert PM et al. Glycerol monolaurate prevents mucosal SIV transmission. Nature 458(7241), 1034-1038 (2009).
    • (2009) Nature , vol.458 , Issue.7241 , pp. 1034-1038
    • Li, Q.1    Estes, J.D.2    Schlievert, P.M.3
  • 33
    • 0036786450 scopus 로고    scopus 로고
    • High levels of viral replication contrast with only transient changes in CD4(+) and CD8(+) cell numbers during the early phase of experimental infection with simian immunodeficiency virus SIVmnd-1 in Mandrillus sphinx
    • Onanga R, Kornfeld C, Pandrea I et al. High levels of viral replication contrast with only transient changes in CD4(+) and CD8(+) cell numbers during the early phase of experimental infection with simian immunodeficiency virus SIVmnd-1 in Mandrillus sphinx. J. Virol. 76(20), 10256-10263 (2002).
    • (2002) J. Virol. , vol.76 , Issue.20 , pp. 10256-10263
    • Onanga, R.1    Kornfeld, C.2    Pandrea, I.3
  • 34
    • 0037343278 scopus 로고    scopus 로고
    • Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia
    • DOI 10.1016/S1074-7613(03)00060-8
    • Silvestri G, Sodora DL, Koup RA et al. Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia. Immunity 18(3), 441-452 (2003). (Pubitemid 36351522)
    • (2003) Immunity , vol.18 , Issue.3 , pp. 441-452
    • Silvestri, G.1    Sodora, D.L.2    Koup, R.A.3    Paiardini, M.4    O'Neil, S.P.5    McClure, H.M.6    Staprans, S.I.7    Feinberg, M.B.8
  • 35
    • 2542426543 scopus 로고    scopus 로고
    • The paradox of simian immunodeficiency virus infection in sooty mangabeys: Active viral replication without disease progression
    • d505-999
    • Chakrabarti LA. The paradox of simian immunodeficiency virus infection in sooty mangabeys: active viral replication without disease progression. Front. Biosci. 9, 521-539 (2004). (Pubitemid 39043732)
    • (2004) Frontiers in Bioscience , vol.9 , pp. 521-539
    • Chakrabarti, L.A.1
  • 37
    • 72849136282 scopus 로고    scopus 로고
    • Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled Type 1 IFN response
    • Jacquelin B, Mayau V, Targat B et al. Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled Type 1 IFN response. J. Clin. Invest. 119(12), 3544-3555 (2009).
    • (2009) J. Clin. Invest. , vol.119 , Issue.12 , pp. 3544-3555
    • Jacquelin, B.1    Mayau, V.2    Targat, B.3
  • 38
    • 0037364804 scopus 로고    scopus 로고
    • Natural versus adaptive regulatory T cells
    • DOI 10.1038/nri1032
    • Bluestone JA, Abbas AK. Natural versus adaptive regulatory T cells. Nat. Rev. Immunol. 3(3), 253-257 (2003). (Pubitemid 37323210)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.3 , pp. 253-257
    • Bluestone, J.A.1    Abbas, A.K.2
  • 39
    • 34548042128 scopus 로고    scopus 로고
    • Strong HIV-1-specific T cell responses in HIV-1-exposed uninfected infants and neonates revealed after regulatory T cell removal
    • Legrand FA, Nixon DF, Loo CP et al. Strong HIV-1-specific T cell responses in HIV-1-exposed uninfected infants and neonates revealed after regulatory T cell removal. PLoS One 1, e102 (2006).
    • (2006) PLoS One , vol.1
    • Legrand, F.A.1    Nixon, D.F.2    Loo, C.P.3
  • 40
    • 50149097478 scopus 로고    scopus 로고
    • Preservation of FoxP3+ regulatory T cells in the peripheral blood of human immunodeficiency virus Type 1-infected elite suppressors correlates with low CD4+ T-cell activation
    • Chase AJ, Yang HC, Zhang H, Blankson JN, Siliciano RF. Preservation of FoxP3+ regulatory T cells in the peripheral blood of human immunodeficiency virus Type 1-infected elite suppressors correlates with low CD4+ T-cell activation. J. Virol. 82(17), 8307-8315 (2008).
    • (2008) J. Virol. , vol.82 , Issue.17 , pp. 8307-8315
    • Chase, A.J.1    Yang, H.C.2    Zhang, H.3    Blankson, J.N.4    Siliciano, R.F.5
  • 41
    • 53449092578 scopus 로고    scopus 로고
    • FoxP3+CD4+ regulatory T cells play an important role in acute HIV-1 infection in humanized Rag2-/-gC-/-mice in vivo
    • Jiang Q, Zhang L, Wang R et al. FoxP3+CD4+ regulatory T cells play an important role in acute HIV-1 infection in humanized Rag2-/-gC-/-mice in vivo. Blood 112(7), 2858-2868 (2008).
    • (2008) Blood , vol.112 , Issue.7 , pp. 2858-2868
    • Jiang, Q.1    Zhang, L.2    Wang, R.3
  • 44
    • 66949111847 scopus 로고    scopus 로고
    • The fate of human Treg cells
    • Battaglia M, Roncarolo MG. The fate of human Treg cells. Immunity 30(6), 763-765 (2009).
    • (2009) Immunity , vol.30 , Issue.6 , pp. 763-765
    • Battaglia, M.1    Roncarolo, M.G.2
  • 45
    • 79955027908 scopus 로고    scopus 로고
    • Memory CCR6+CD4+ T cells are preferential targets for productive HIV Type 1 infection regardless of their expression of integrin b7
    • Monteiro P, Gosselin A, Wacleche VS et al. Memory CCR6+CD4+ T cells are preferential targets for productive HIV Type 1 infection regardless of their expression of integrin b7. J. Immunol. 186(8), 4618-4630 (2011).
    • (2011) J. Immunol. , vol.186 , Issue.8 , pp. 4618-4630
    • Monteiro, P.1    Gosselin, A.2    Wacleche, V.S.3
  • 46
    • 45949112196 scopus 로고    scopus 로고
    • CD127 and CD25 expression defines CD4+ T cell subsets that are differentially depleted during HIV infection
    • Dunham RM, Cervasi B, Brenchley JM et al. CD127 and CD25 expression defines CD4+ T cell subsets that are differentially depleted during HIV infection. J. Immunol. 180(8), 5582-5592 (2008).
    • (2008) J. Immunol. , vol.180 , Issue.8 , pp. 5582-5592
    • Dunham, R.M.1    Cervasi, B.2    Brenchley, J.M.3
  • 47
    • 79954620910 scopus 로고    scopus 로고
    • Th17 cells express interleukin-10 receptor and are controlled by Foxp3(-) and Foxp3(+) regulatory CD4(+) T cells in an interleukin-10-dependent manner
    • Huber S, Gagliani N, Esplugues E et al. Th17 cells express interleukin-10 receptor and are controlled by Foxp3(-) and Foxp3(+) regulatory CD4(+) T cells in an interleukin-10-dependent manner. Immunity 34(4), 554-565 (2011).
    • (2011) Immunity , vol.34 , Issue.4 , pp. 554-565
    • Huber, S.1    Gagliani, N.2    Esplugues, E.3
  • 48
    • 0033731101 scopus 로고    scopus 로고
    • A multicenter, randomized, double-blind, placebo-controlled trial of recombinant human interleukin-10 in HIV-infected subjects
    • Angel JB, Jacobson MA, Skolnik PR et al. A multicenter, randomized, double-blind, placebo-controlled trial of recombinant human interleukin-10 in HIV-infected subjects. AIDS 14(16), 2503-2508 (2000).
    • (2000) AIDS , vol.14 , Issue.16 , pp. 2503-2508
    • Angel, J.B.1    Jacobson, M.A.2    Skolnik, P.R.3
  • 50
    • 38749096240 scopus 로고    scopus 로고
    • The failed HIV Merck vaccine study: A step back or a launching point for future vaccine development?
    • Sekaly RP. The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development? J. Exp. Med. 205(1), 7-12 (2008).
    • (2008) J. Exp. Med. , vol.205 , Issue.1 , pp. 7-12
    • Sekaly, R.P.1
  • 51
    • 0037339812 scopus 로고    scopus 로고
    • Regulatory dendritic cells protect mice from murine acute graft-versus-host disease and leukemia relapse
    • DOI 10.1016/S1074-7613(03)00055-4
    • Sato K, Yamashita N, Baba M, Matsuyama T. Regulatory dendritic cells protect mice from murine acute graft-versus-host disease and leukemia relapse. Immunity 18(3), 367-379 (2003). (Pubitemid 36351516)
    • (2003) Immunity , vol.18 , Issue.3 , pp. 367-379
    • Sato, K.1    Yamashita, N.2    Yamashita, N.3    Baba, M.4    Matsuyama, T.5
  • 52
    • 0012391130 scopus 로고    scopus 로고
    • Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells
    • DOI 10.1182/blood-2002-09-2712
    • Sato K, Yamashita N, Baba M, Matsuyama T. Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells. Blood 101(9), 3581-3589 (2003). (Pubitemid 36857945)
    • (2003) Blood , vol.101 , Issue.9 , pp. 3581-3589
    • Sato, K.1    Yamashita, N.2    Baba, M.3    Matsuyama, T.4
  • 55
    • 58149127260 scopus 로고    scopus 로고
    • IL-10-secreting T cells from HIV-infected pregnant women downregulate HIV-1 replication: Effect enhanced by antiretroviral treatment
    • Bento CA, Hygino J, Andrade RM et al. IL-10-secreting T cells from HIV-infected pregnant women downregulate HIV-1 replication: effect enhanced by antiretroviral treatment. AIDS 23(1), 9-18 (2009).
    • (2009) AIDS , vol.23 , Issue.1 , pp. 9-18
    • Bento, C.A.1    Hygino, J.2    Andrade, R.M.3
  • 56
    • 79956339815 scopus 로고    scopus 로고
    • Regulatory T cells control HIV replication in activated T cells through a cAMP-dependent mechanism
    • Moreno-Fernandez ME, Rueda CM, Rusie LK, Chougnet CA. Regulatory T cells control HIV replication in activated T cells through a cAMP-dependent mechanism. Blood 117(20), 5372-5380 (2011).
    • (2011) Blood , vol.117 , Issue.20 , pp. 5372-5380
    • Moreno-Fernandez, M.E.1    Rueda, C.M.2    Rusie, L.K.3    Chougnet, C.A.4
  • 57
    • 61449115882 scopus 로고    scopus 로고
    • Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection
    • Favre D, Lederer S, Kanwar B et al. Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection. PLoS Pathog. 5(2), e1000295 (2009).
    • (2009) PLoS Pathog. , vol.5 , Issue.2
    • Favre, D.1    Lederer, S.2    Kanwar, B.3
  • 58
    • 76949108202 scopus 로고    scopus 로고
    • Th17 and regulatory T cells: Implications for AIDS pathogenesis
    • Kanwar B, Favre D, McCune JM. Th17 and regulatory T cells: implications for AIDS pathogenesis. Curr. Opin. HIV AIDS 5(2), 151-157 (2010).
    • (2010) Curr. Opin. HIV AIDS , vol.5 , Issue.2 , pp. 151-157
    • Kanwar, B.1    Favre, D.2    McCune, J.M.3
  • 59
    • 10744227590 scopus 로고    scopus 로고
    • + Regulatory T Cells Control T-Cell Responses to Human Immunodeficiency Virus and Cytomegalovirus Antigens
    • DOI 10.1128/JVI.78.5.2454-2459.2004
    • Aandahl EM, Michaelsson J, Moretto WJ, Hecht FM, Nixon DF. Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens. J. Virol. 78(5), 2454-2459 (2004). (Pubitemid 38228938)
    • (2004) Journal of Virology , vol.78 , Issue.5 , pp. 2454-2459
    • Aandahl, E.M.1    Michaelsson, J.2    Moretto, W.J.3    Hecht, F.M.4    Nixon, D.F.5
  • 60
    • 8644280556 scopus 로고    scopus 로고
    • + regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients
    • DOI 10.1182/blood-2004-01-0365
    • Weiss L, Donkova-Petrini V, Caccavelli L, Balbo M, Carbonneil C, Levy Y. Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients. Blood 104(10), 3249-3256 (2004). (Pubitemid 39507143)
    • (2004) Blood , vol.104 , Issue.10 , pp. 3249-3256
    • Weiss, L.1    Donkova-Petrini, V.2    Caccavelli, L.3    Balbo, M.4    Carbonneil, C.5    Levy, Y.6
  • 61
    • 34547214205 scopus 로고    scopus 로고
    • Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans
    • DOI 10.1038/nri2138, PII NRI2138
    • Roncarolo MG, Battaglia M. Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans. Nat. Rev. Immunol. 7(8), 585-598 (2007). (Pubitemid 47123554)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.8 , pp. 585-598
    • Roncarolo, M.-G.1    Battaglia, M.2


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