Secretome of human bronchial epithelial cells in response to the fungal pathogen Aspergillus fumigatus analyzed by differential in-gel electrophoresis

Journal of Infectious Diseases

Volumn 205, Issue 7, 2012, Pages 1163-1172

  Fekkar, A ^a,b,c   Balloy, V ^a,d   Pionneau, C ^b   Marinach Patrice, C ^a   Chignard, M ^a,d   Mazier, D ^a,b,c  

^a INSERM   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^d INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN B; INTERLEUKIN 8; LYSOSOME ENZYME; MITOGEN ACTIVATED PROTEIN KINASE P38; N ACETYL BETA GLUCOSAMINIDASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEINASE; THIOREDOXIN;

APOPTOSIS; ARTICLE; ASPERGILLOSIS; BRONCHUS MUCOSA; CELL ACTIVITY; CELL CULTURE; CELL DEATH; CELL INTERACTION; CELLULAR IMMUNITY; COCULTURE; CONTROLLED STUDY; DEFENSE MECHANISM; DEGRANULATION; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME RELEASE; EPITHELIUM CELL; FUNGUS GROWTH; GEL ELECTROPHORESIS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOBLOTTING; INFECTION RESISTANCE; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEOMICS; SUPERNATANT;

ASPERGILLUS FUMIGATUS; CELL LINE; COCULTURE TECHNIQUES; CULTURE MEDIA; ELECTROPHORESIS; EPITHELIAL CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; PROTEINS; PROTEOME; RESPIRATORY MUCOSA;

EID: 84858214763     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jis031     Document Type: Article

References (37)

1. Schaffner A, Douglas H, Braude A. Selective protection against conidia by mononuclear and against mycelia by polymorphonuclear phagocytes in resistance to Aspergillus: observations on these two lines of defense in vivo and in vitro with human and mouse phagocytes. J Clin Invest 1982; 69:617-31. (Pubitemid 12184959)
2. Waldorf AR, Levitz SM, Diamond RD. In vivo bronchoalveolar macrophage defense against Rhizopus oryzae and Aspergillus fumigatus. J Infect Dis 1984; 150:752-60. (Pubitemid 15200085)
3. Diamond RD, Clark RA. Damage to Aspergillus fumigatus and Rhizopus oryzae hyphae by oxidative and nonoxidative microbicidal products of human neutrophils in vitro. Infect Immun 1982; 38:487-95. (Pubitemid 12002663)
4. Stevens DA, Moss RB, Kurup VP, et al. Allergic bronchopulmonary aspergillosis in cystic fibrosis-state of the art: Cystic Fibrosis Foundation Consensus Conference. Clin Infect Dis 2003; 37(Suppl 3):S225-64. (Pubitemid 37260463)
5. Denning DW, Riniotis K, Dobrashian R, Sambatakou H. Chronic cavitary and fibrosing pulmonary and pleural aspergillosis: case series, proposed nomenclature change, and review. Clin Infect Dis 2003; 37(Suppl 3):S265-80. (Pubitemid 37260464)
6. Takizawa H. Bronchial epithelial cells in allergic reactions. Curr Drug Targets Inflamm Allergy 2005; 4:305-11. (Pubitemid 40873116)
7. Paris S, Boisvieux-Ulrich E, Crestani B, et al. Internalization of Aspergillus fumigatus conidia by epithelial and endothelial cells. Infect Immun 1997; 65:1510-4. (Pubitemid 27146645)
8. Balloy V, Chignard M. The innate immune response to Aspergillus fumigatus. Microbes Infect 2009; 11:919-27.
9. Tomee JF, Wierenga AT, Hiemstra PS, Kauffman HK. Proteases from Aspergillus fumigatus induce release of proinflammatory cytokines and cell detachment in airway epithelial cell lines. J Infect Dis 1997; 176:300-3. (Pubitemid 27272890)
10. Zhang Z, Liu R, Noordhoek JA, Kauffman HF. Interaction of airway epithelial cells (A549) with spores and mycelium of Aspergillus fumigatus. J Infect 2005; 51:375-82. (Pubitemid 43008961)
11. Balloy V, Sallenave JM, Wu Y, et al. Aspergillus fumigatus-induced interleukin-8 synthesis by respiratory epithelial cells is controlled by the phosphatidylinositol 3-kinase, p38 MAPK, and ERK1/2 pathways and not by the toll-like receptor-MyD88 pathway. J Biol Chem 2008; 283:30513-21.
12. Botterel F, Gross K, Ibrahim-Granet O, et al. Phagocytosis of Aspergillus fumigatus conidia by primary nasal epithelial cells in vitro. BMC Microbiol 2008; 8:97.
13. Blott EJ, Griffiths GM. Secretory lysosomes. Nat Rev Mol Cell Biol 2002; 3:122-31.
14. Perrot A, Pionneau C, Nadaud S, et al. A unique proteomic profile upon surface IgM ligation in unmutated chronic lymphocytic leukemia. Blood 2011; 118(4):e1-15.
15. Urb M, Pouliot P, Gravelat FN, Olivier M, Sheppard DC. Aspergillus fumigatus induces immunoglobulin E-independent mast cell degranulation. J Infect Dis 2009; 200:464-72.
16. Docherty K, Hutton JC, Steiner DF. Cathepsin B-related proteases in the insulin secretory granule. J Biol Chem 1984; 259:6041-4. (Pubitemid 14106305)
17. Sloane BF, Moin K, Sameni M, Tait LR, Rozhin J, Ziegler G. Membrane association of cathepsin B can be induced by transfection of human breast epithelial cells with c-Ha-ras oncogene. J Cell Sci 1994; 107:373-84. (Pubitemid 24072871)
18. San Segundo B, Chan SJ, Steiner DF. Identification of cDNA clones encoding a precursor of rat liver cathepsin B. Proc Natl Acad Sci U S A 1985; 82:2320-4. (Pubitemid 15064479)
19. Johansson AC, Appelqvist H, Nilsson C, Kagedal K, Roberg K, Ollinger K. Regulation of apoptosis-associated lysosomal membrane permeabilization. Apoptosis 2010; 15:527-40.
20. Kroemer G, Galluzzi L, Vandenabeele P, et al. Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ 2009; 16:3-11.
21. Jiang H, Zhu YS, Xu H, Sun Y, Li QF. Inflammatory stimulation and hypoxia cooperatively activate HIF-1{alpha} in bronchial epithelial cells: involvement of PI3K and NF-{kappa}B. Am J Physiol Lung Cell Mol Physiol 2010; 298:L660-9.
22. Kinnula VL, Yankaskas JR, Chang L, et al. Primary and immortalized (BEAS 2B) human bronchial epithelial cells have significant antioxidative capacity in vitro. Am J Respir Cell Mol Biol 1994; 11:568-76.
23. Atsuta J, Plitt J, Bochner BS, Schleimer RP. Inhibition of VCAM-1 expression in human bronchial epithelial cells by glucocorticoids. Am J Respir Cell Mol Biol 1999; 20:643-50. (Pubitemid 129495652)
24. Wasylnka JA, Moore MM. Uptake of Aspergillus fumigatus conidia by phagocytic and nonphagocytic cells in vitro: quantitation using strains expressing green fluorescent protein. Infect Immun 2002; 70:3156-63. (Pubitemid 34564179)
25. Hohl TM, Van Epps HL, Rivera A, et al. Aspergillus fumigatus triggers inflammatory responses by stage-specific beta-glucan display. PLoS Pathog 2005; 1:e30.
26. Koo IC, Ohol YM, Wu P, Morisaki JH, Cox JS, Brown EJ. Role for lysosomal enzyme beta-hexosaminidase in the control of mycobacteria infection. Proc Natl Acad Sci U S A 2008; 105:710-5. (Pubitemid 351171773)
27. Lew DB, Chodimella V, Murlas CG. Guinea pig ozone-induced airway hyperreactivity is associated with increased N-acetyl-beta-D-glucosaminidase activity in bronchoalveolar lavage fluid. Lung 1990; 168:273-83. (Pubitemid 20364627)
28. Boya P, Gonzalez-Polo RA, Poncet D, et al. Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine. Oncogene 2003; 22:3927-36. (Pubitemid 36819666)
29. Rommelaere G, Michel S, Mercy L, et al. Hypersensitivity of mtDNA-depleted cells to staurosporine-induced apoptosis: the roles of Bcl-2 downregulation and cathepsin B. Am J Physiol Cell Physiol 2011; 300(5):C1090-106.
30. Linebaugh BE, Sameni M, Day NA, Sloane BF, Keppler D. Exocytosis of active cathepsin B enzyme activity at pH 7.0, inhibition and molecular mass. Eur J Biochem 1999; 264:100-9. (Pubitemid 29385872)
31. Martin SL, Moffitt KL, McDowell A, et al. Association of airway cathepsin B and S with inflammation in cystic fibrosis. Pediatr Pulmonol 2010; 45:860-8.
32. Mahavadi P, Korfei M, Henneke I, et al. Epithelial stress and apoptosis underlie Hermansky-Pudlak syndrome-associated interstitial pneumonia. Am J Respir Crit Care Med 2010; 182:207-19.
33. Gomez P, Hackett TL, Moore MM, Knight DA, Tebbutt SJ. Functional genomics of human bronchial epithelial cells directly interacting with conidia of Aspergillus fumigatus. BMC Genomics 2010; 11:358.
34. Nakamura H. Thioredoxin as a key molecule in redox signaling. Antioxid Redox Signal 2004; 6:15-7. (Pubitemid 38063972)
35. Sato A, Hoshino Y, Hara T, et al. Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysema in mice. J Pharmacol Exp Ther 2008; 325:380-8. (Pubitemid 351574797)
36. Kaimul Ahsan M, Nakamura H, Tanito M, Yamada K, Utsumi H, Yodoi J. Thioredoxin-1 suppresses lung injury and apoptosis induced by diesel exhaust particles (DEP) by scavenging reactive oxygen species and by inhibiting DEP-induced downregulation of Akt. Free Radic Biol Med 2005; 39:1549-59. (Pubitemid 41642586)
37. Saitoh M, Nishitoh H, Fujii M, et al. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J 1998; 17:2596-606. (Pubitemid 28221195)