Low dose of propranolol down-modulates bone resorption by inhibiting inflammation and osteoclast differentiation

British Journal of Pharmacology

Volumn 165, Issue 7, 2012, Pages 2140-2151

  Rodrigues, W F ^a   Madeira, M F M ^b   Da Silva, T A ^b   Clemente Napimoga, J T ^c   Miguel, C B ^d   Dias Da Silva, V J ^d   Barbosa Neto, O ^d   Lopes, A H ^a   Napimoga, M H ^a,e  

^a UNIVERSITY OF UBERABA   (Brazil)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^c UNIVERSITY OF CAMPINAS   (Brazil)

^d FEDERAL UNIVERSITY OF TRIÂNGULO MINEIRO   (Brazil)

^e SÃO LEOPOLDO MANDIC INSTITUTE AND RESEARCH CENTER   (Brazil)

Author keywords

blocker; bone; inflammation; periodontal disease; propranolol

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; CARBOXY TERMINAL TELOPEPTIDE; CATHEPSIN K; GELATINASE B; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PROPRANOLOL; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFAT1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFICACY; ENZYME INHIBITION; ENZYME REPRESSION; HEART CATHETERIZATION; HEMODYNAMICS; IN VITRO STUDY; LOW DRUG DOSE; MALE; MODULATION; NONHUMAN; OSTEOCLASTOGENESIS; OSTEOLYSIS; PERIODONTITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; TREATMENT RESPONSE;

ACID PHOSPHATASE; ALVEOLAR BONE LOSS; ANIMALS; BONE RESORPTION; CATHEPSIN K; CELL DIFFERENTIATION; CELL LINE; COLLAGEN TYPE I; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; GINGIVA; HEMODYNAMICS; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1BETA; ISOENZYMES; MALE; MATRIX METALLOPROTEINASE 9; MICE; NFATC TRANSCRIPTION FACTORS; OSTEOCLASTS; PEPTIDES; PROPRANOLOL; RANK LIGAND; RATS; RATS, WISTAR; RNA, MESSENGER; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84858213536     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01686.x     Document Type: Article

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