Blockade of sympathetic β-receptors inhibits Porphyromonas gingivalis-induced alveolar bone loss in an experimental rat periodontitis model

Archives of Oral Biology

Volumn 55, Issue 7, 2010, Pages 502-508

  Okada, Yuka ^a   Hamada, Nobushiro ^a   Kim, Yul ^a   Takahashi, Yusuke ^a   Sasaguri, Kenichi ^a   Ozono, Satoru ^a   Sato, Sadao ^a  

^a KANAGAWA DENTAL COLLEGE   (Japan)

Author keywords

Blocker; Alveolar bone loss; Porphyromonas gingivalis; Sympathetic nervous system

Indexed keywords

PORPHYROMONAS GINGIVALIS; RATTUS;

ACID PHOSPHATASE; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BIOLOGICAL MARKER; COLORING AGENT; DIAGNOSTIC AGENT; FLUORESCENT DYE; ISOENZYME; PROPRANOLOL; TARTRATE-RESISTANT ACID PHOSPHATASE;

ADRENERGIC SYSTEM; ALVEOLAR BONE LOSS; ANIMAL; ARTICLE; BACTEROIDACEAE INFECTION; BODY WEIGHT; CELL DIFFERENTIATION; DISEASE MODEL; DRUG EFFECT; JAW; MALE; MICROBIOLOGY; ORGAN SIZE; OSTEOCLAST; PATHOLOGY; PERIODONTITIS; PHYSIOLOGY; PORPHYROMONAS GINGIVALIS; RAT; SPLEEN; SPRAGUE DAWLEY RAT; THYMUS;

ACID PHOSPHATASE; ADRENERGIC BETA-ANTAGONISTS; ALVEOLAR BONE LOSS; ALVEOLAR PROCESS; ANIMALS; BACTEROIDACEAE INFECTIONS; BIOLOGICAL MARKERS; BODY WEIGHT; CELL DIFFERENTIATION; COLORING AGENTS; DISEASE MODELS, ANIMAL; FLUORESCENT DYES; ISOENZYMES; MALE; ORGAN SIZE; OSTEOCLASTS; PERIODONTITIS; PORPHYROMONAS GINGIVALIS; PROPRANOLOL; RATS; RATS, SPRAGUE-DAWLEY; SPLEEN; SYMPATHETIC NERVOUS SYSTEM; THYMUS GLAND;

EID: 77955428595     PISSN: 00039969     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.archoralbio.2010.04.002     Document Type: Article

References (32)

1. T. Breivik, P.S. Thrane, P. Gjermo, and P.K. Opstad Glucocorticoid receptor antagonist RU 486 treatment reduces periodontitis in Fischer 344 rats J Periodontal Res 35 5 2000 285 290
2. T. Breivik, Y. Gundersen, F. Fonnum, P. Vaagenes, and P.K. Opstad Chronic glycine treatment inhibits ligature-induced periodontal disease in Wistar rats J Periodontal Res 40 1 2005 43 47 (Pubitemid 40186625)
3. R.J. Lamont, and H.F. Jenkinson Life below the gum line: pathogenic mechanisms of Porphyromonas gingivalis Microbiol Mol Biol Rev 62 4 1998 1244 1263
4. R.J. Genco Current view of risk factors for periodontal diseases J Periodontol 67 10 1996 1041 1049
5. I.J. Singh, M.S. Herskovits, D.J. Chiego Jr., and R.M. Klein Modulation of osteoblastic activity by sensory and autonomic innervation of bone Prog Clin Biol Res 101 1982 535 551
6. S.R. Haug, and K.J. Heyeraas Modulation of dental inflammation by the sympathetic nervous system J Dent Res 85 6 2006 488 495
7. T. Breivik, P.S. Thrane, R. Murison, and P. Gjermo Emotional stress effects on immunity, gingivitis and periodontitis Eur J Oral Sci 104 4 1996 327 334
8. M. Ladizesky, M.A. Lama, E.J. Roldán, R.A. Cutrera, V. Boggio, and M.J. Giglio Effect of unilateral superior cervical ganglionectomy on mandibular bone in rats Neuro Endocrinol Lett 24 5 2003 314 320
9. M.G. Ladizesky, R.A. Cutrera, V. Boggio, C. Mautalen, and D.P. Cardinali Effect of unilateral superior cervical ganglionectomy on bone mineral content and density of rat's mandible J Auton Nerv Syst 78 2-3 2000 113 116
10. A. Togari Adrenergic regulation of bone metabolism: possible involvement of sympathetic innervation of osteoblastic and osteoclastic cells Microsc Res Technol 58 2 2002 77 84
11. N.R. Hall, and A.L. Goldstein Endocrine regulation of host immunity R.L. Fenichel, M.A. Chirogos, Immune modulation agents and their mechanisms 1984 Marcel Dekker New York 533 563
12. V.K. Singh, R.P. Warren, R.D. White, and S.J.C. Leu Corticotropin- releasing factor induced stimulation of immune functions Ann NY Acad Sci 594 1990 416 419
13. P.W. Mantyh Substance P and the inflammatory and immune response Ann NY Acad Sci 632 1991 263 271
14. A. Bletsa, K.J. Heyeraas, S.R. Haug, and E. Berggreen IL-1 alpha and TNF-alpha expression in rat periapical lesions and dental pulp after unilateral sympathectomy Neuroimmunomodulation 11 6 2004 376 384
15. R.J. Genco, A.W. Ho, S.G. Grossi, R.G. Dunford, and L.A. Tedesco Relationship of stress, distress and inadequate coping behaviors to periodontal disease J Periodontol 70 7 1999 711 723
16. D.D. Pierroz, M.L. Bouxsein, R. Rizzoli, and S.L. Ferrari Combined treatment with a beta-blocker and intermittent PTH improves bone mass and microarchitecture in ovariectomized mice Bone 39 2 2006 260 267
17. I.R. Reid, J. Lucas, D. Wattie, A. Horne, M. Bolland, and G.D. Gamble A.B. Grey Effects of a beta-blocker on bone turnover in normal postmenopausal women: a randomized controlled trial J Clin Endocrinol Metab 90 9 2005 5212 5216
18. L.F. Valdivia, D. Centurión, M. Perusquía, U. Arulmani, P.R. Saxena, and C.M. Villalón Pharmacological analysis of the mechanisms involved in the tachycardic and vasopressor responses to the antimigraine agent, isometheptene, in pithed rats Life Sci 74 26 2004 3223 3234
19. K. Nakajima, N. Hamada, Y. Takahashi, K. Sasaguri, K. Tsukinoki, and T. Umemoto Restraint stress enhances alveolar bone loss in an experimental rat model J Periodontal Res 41 6 2006 527 534
20. N. Hamada, K. Watanabe, T. Tahara, K. Nakazawa, I. Ishida, Y. Shibata H. Yoshie, and T. Umemoto The r40-kDa outer membrane protein human monoclonal antibody protects against Porphyromonas gingivalis-induced bone loss in rats J Periodontol 78 5 2007 933 939
21. A. De Luigi, L. Terreni, M. Sironi, and M.G. De Simoni The sympathetic nervous system tonically inhibits peripheral interleukin-1beta and interleukin-6 induction by central lipopolysaccharide Neuroscience 83 4 1998 1245 1250
22. S. Takeda, F. Elefteriou, R. Levasseur, X. Liu, L. Zhao, and K.L. Parker P. Ducy Leptin regulates bone formation via the sympathetic nervous system Cell 111 3 2002 305 317
23. A. Togari, and M. Arai Pharmacological topics of bone metabolism: the physiological function of the sympathetic nervous system in modulating bone resorption J Pharmacol Sci 106 4 2008 542 546
24. Y. Kim, N. Hamada, Y. Takahashi, K. Sasaguri, K. Tsukinoki, and M. Onozuka Cervical sympathectomy causes alveolar bone loss in an experimental rat model J Periodont Res 44 6 2009 695 703
25. A.C. O'Connell, B.C. Van Wuyckhuyse, S.K. Pearson, and W.H. Bowen The effect of propranolol on salivary gland function and dental caries development in young and aged rats Arch Oral Biol 38 10 1993 853 861
26. F. Elefteriou, J.D. Ahn, S. Takeda, M. Starbuck, X. Yang, X. Liu W.G. Richards, M. Noda, and C. Vaisse Leptin regulation of bone resorption by the sympathetic nervous system and CART Nature 434 7032 2005 514 520
27. S. Turker, V. Karatosun, and I. Gunal Beta-blockers increase bone mineral density Clin Orthop Relat Res 443 2006 73 74
28. M. Dimitrijević, A. Rauki, K. Radojević, D. Kosec, S. Stanojević, and I. Pilipović β-Adrenoceptor blockade ameliorates the clinical course of experimental allergic encephalomyelitis and diminishes its aggravation in adrenalectomized rats Eur J Pharmacol 577 1-3 2007 170 182
29. Y.D. Bai, F.S. Yang, K. Xuan, Y.X. Bai, and B.L. Wu Inhibition of RANK/RANKL signal transduction pathway: a promising approach for osteoporosis treatment Med Hypotheses 71 2 2008 256 258
30. S. Cohen, and G.M. Williamson Stress and infectious disease in humans Psychol Bull 109 1 1991 5 24
31. J.F. Sheridan, C. Dobbs, D. Brown, and B. Zwilling Psychoneuroimmunology: stress effects on pathogenesis and immunity during infection Clin Microbiol Rev 7 2 1994 200 212
32. J.E. Blalock The syntax of immune-neuroendocrine communication Immunol Today 15 11 1994 504 511