Can a chronic dental infection be considered a cause of cardiovascular disease? A review of the literature

International Journal of Cardiology

Volumn 148, Issue 1, 2011, Pages 4-10

  Cotti, Elisabetta ^a   Dessì, Cristina ^a   Piras, Alessandra ^a   Mercuro, Giuseppe ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

Apical periodontitis; Cardiovascular disease; Periodontal disease

Indexed keywords

ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CYTOKINE RELEASE; DENTAL HEALTH; DISEASE ASSOCIATION; ENDODONTICS; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; ISCHEMIC HEART DISEASE; MEDLINE; NONHUMAN; PATHOGENESIS; PERIODONTAL DISEASE; PORPHYROMONAS GINGIVALIS; PRIORITY JOURNAL; REVIEW; SYSTEMATIC REVIEW; TOOTH EXTRACTION; TOOTH INFECTION; TOOTH PERIAPICAL DISEASE;

ANIMALS; CARDIOVASCULAR DISEASES; CHRONIC DISEASE; HUMANS; PERIAPICAL PERIODONTITIS; PERIODONTAL DISEASES; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TOOTH DISEASES;

EID: 79952818489     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2010.08.011     Document Type: Review

References (60)

1. Hegele RA. The pathogenesis of atherosclerosis. Clin Chim Acta 1996;246:21-38. (Pubitemid 26096380)
2. Stöllberger C, Finsterer J. Role of infectious and immune factors in coronary and cerebrovascular arteriosclerosis. Clin Diagn Lab Immunol 2002;9(2):207-15. (Pubitemid 34226008)
3. Naoum JJ, Chai H, Lin PH, Lumsden AB, Yao Q, Chen C. Lymphotoxin-a and cardiovascular disease: clinical association and pathogenic mechanisms. Med Sci Monit 2006;12(7):RA121-4.
4. Abbas M, Bignamini V, Corea F. Effects of chronic microbial infection on atherosclerosis. Atherosclerosis 2006;187:439-40. (Pubitemid 43963032)
5. Epstein SE, Zhou YF, Zhu J. Infection and atherosclerosis. Emerging mechanistic paradigms. Circulation 1999;100:20-8.
6. Patel P, Mendall MA, Carrington D, et al. Association of Helicobacter pylori and Chlamydia pneumoniae infections with coronary heart disease and cardiovascular risk factors. BMJ 1995;311:711-4.
7. Martin-de-Argila C, Boixeda D, Canton R, Gisbert JP, Fuertes A. High seroprevalence of Helicobacter pylori infection in coronary heart disease. Lancet 1995;346:310.
8. Cook PJ, Honeybourne D, Lip GYH, Beevers DG, Wise R, Davies P. Chlamydia pneumoniae antibody titers are significantly associated with acute stroke and transient cerebral ischemia: the West Birmingham Stroke Project. Stroke 1998;29:404-10. (Pubitemid 28086683)
9. Beck JD, Pankow J, Tyroler HA, Offenbacher S. Dental infections and atherosclerosis. Am Heart J 1999;138:528-33.
10. Niedzielska I, Janic T, Cierpka S, Świȩtochowska E. The effect of chronic periodontitis on the development of atherosclerosis: review of the literature. Med Sci Monit 2008;14(7):103-6.
11. Armitage GC. Development of a classification system for periodontal diseases and conditions. Ann Periodontol 1999;4:1.
12. Carranza's: Clinical Periodontology. Elsevier ed10th edition. St. Louis: Missouri; 2006.
13. Metzger Z, Abramovitz I. Periapical Lesions of Endodontic Origin. In: Ingle JI, Bakland LK, Baumgartner JC, editors. Ingle's Endodontics. 6th edition. Hamilton Ontario BC: Decker Inc; 2008. p. 494-519.
14. Sundqvist G. Ecology of the root canal flora. J Endod 1992;18:427-30.
15. Noiri Y, Li L, Ebisu S. The localization of periodontal-disease associated bacteria in human periodontal pockets. J Dent Res 2001;80:1930-4. (Pubitemid 33038063)
16. Barkhordar RA, Hayashi C, Hussain MZ. Detection of interleukin-6 in human dental pulp and periapical lesion. Endod Dent Traumotol 1999;15:26-7.
17. Gamonal J, Acevedo A, Bascones A, Jorge O, Silva A. Levels of interleukin-1 beta, -8, and -10 and Rantes in gingival crevicular fluid and cell population in adult periodontitis patiens and the effect of periodontal treatment. J Periodontol 2000;71:1535-45.
18. Thoden van Velzen SK, Abraham-Inpijn L,MoorerWR. Plaque and systemic disease: a reappraisal of the focal infection concept. J Clin Periodontol 1984;11:209-20.
19. De Stefano F, Anda RF, Kahn HS, Williamson DF, Russell CM. Dental disease and risk of coronary heart disease and mortality. Br Med J 1993;306:688-91. (Pubitemid 23070231)
20. Bochniak M, Sadlak-Nowicka J. Periodontitis and cardiovascular disease: literature review. Przegl Lek 2004;61(5):519-22.
21. Slots J. Subgingival microflora and periodontal disease. J Clin Periodontol 1979;6:351-82. (Pubitemid 10191677)
22. Slots J. Actinobacillus actinomycetemcomitans and Porphromonas gingivalis in human periodontal disease: Occurrence and treatment. Periodontology 2000 1999;20:82-121.
23. Mattila K, Nieminen MS, Valtonen VV, et al. Association between dental health and acute myocardial infarction. Br Med J 1989;298:779-82.
24. Beck JD, Garcia R, Heiss G, Vokonas P, Offenbacher S. Periodontal disease and cardiovascular disease. J Periodontol 1996;67:1123-37. (Pubitemid 126613093)
25. Joshipura KJ, Rimm EB, Douglass CV, Trichopoulos D, Ascherio A, Willett WC. Poor oral health and coronary heart disease. J Dent Res 1996;75:1631-6. (Pubitemid 32763637)
26. Grau AJ, Buggle F, Siegler C. Association between acute cerebrovascular ischaemia and chronic and recurrent infection. Stroke 1997;28:1724-9. (Pubitemid 27391439)
27. Jansson L, Lavstedt S, Frithiof S, Theobald H. Relationship between oral health and mortality in cardiovascular diseases. J Clin Periodontol 2001;28:762-8. (Pubitemid 33761317)
28. Herzberg M, Meyer MV. Effects of oral flora on platelets: possible consequences in cardiovascular disease. J Periodontol 1996;67(Suppl):1138.
29. Deshpande RG, Khan MB, Genco CA. Invasion of aortic and heart endothelial cells by Porphyromonas gingivalis. Infect Immun 1998;66:5337.
30. Haraszthy V, Zambon J, Trevisan M. Identification of periodontal pathogens in atheromatous plaques. J Periodontol 2000;71:1554-60.
31. Kuramitsu HK, Qi M, Kang I, Chen W. Role of periodontal bacteria in cardiovascular diseases. Ann Periodontol 2001;6:41-7.
32. Beck JD, Elter JR, Heiss G, Couper D, Mauriello SM, Offenbacher S. Relationship of periodontal disease to carotid artery intima-media wall thickness: the atherosclerosis risk in communities (ARIC) study. Arterioscler Thromb Vasc Biol 2001;21:1816-22. (Pubitemid 34219786)
33. Persson RE, Hollender LG, Powell VL, et al. Assessment of periodontal conditions and systemic disease in older subjects. II. Focus on cardiovascular diseases. J Clin Periodontol 2002;29:803-10. (Pubitemid 41697795)
34. Stelzel M, Caurads G, Pankuweit S. Detection of Porphyromonas gingivalis DNA in aortic tissue by PCR. J Periodontol 2002;73:868.
35. D'Aiuto F, Ready D, Tonetti M. Periodontal disease and C-reactive protein-associated cardiovascular risk. J Periodontal Res 2004;4:236-41. (Pubitemid 38969606)
36. Cavrini F, Sambri V, Moter A, et al. Molecular detection of Treponema denticola and Porphyromonas gingivalis in carotid and aortic atheromatous claque by FISH: report of two cases. J Med Microbiol 2005;54:93-5.
37. Nair PRN. Pathogenesis of apical periodontitis and the causes of endodontic failures. Crit Rev Oral Biol Med 2004;15-6:348-81.
38. Baumgartner JC, Siqueira JR, Sedgley CM, Kishen A. Microbiology of Endodontic Disease. In: Ingle JI, Bakland LK, Baumgartner JC, editors. Ingle's Endodontics. 6th edition. Hamilton Ontario: BC Decker Inc; 2008. p. 221-308.
39. Caplan DJ, Pankow J, Cai J, Offenbacher S, Beck J. Endodontic infection and coronary heart disease in the ARIC study. Presented at the IADR/AADR/CADR 80th General Session, San Diego, California, March 6-9, 2002 [abstract #3528].
40. Caplan DJ, Chasen JB, Krall EA, et al. Lesions of endodontic origin and risk of coronary heart disease. J Dent Res 2006;85(11):996-1000. (Pubitemid 44706655)
41. Debelian GJ, Olsen I, Tronstad L. Systemic diseases caused by oral microorganisms. Endod Dent Traumatol 1994;10:57-65.
42. American Association of Endodontists. Oral disease and systemic health: what is the connection? Endodontics: colleagues for excellence 2000;2:1-4.
43. Debelian GJ, Olsen I, Tronstad L. Bacteremia in conjunction with endodontic therapy. Endod Dent Traumatol 1995;11:142-9.
44. Savarrio L, McKenzie D, Riggio M, et al. Detection of bacteremias during nonsurgical root canal treatment. J Dent 2005;33:293-303. (Pubitemid 40386851)
45. Heimdahl A, Hall G, Hedelberg M, Sandberg H. Detection and quantitation by lysisfiltration of bacteremia after different oral surgical procedures. J Clin Microbiol 1990;28:2205-9. (Pubitemid 20299108)
46. Pallasch TJ. Antibiotic prophylaxis. Endod Top 2003;4:46-59.
47. Frisk F, Hakeberg M, Ahlqwist M, Bengtsson C. Endodontic variables and coronary heart disease. Acta Odontol Scand 2003;61:257.
48. Caplan DJ. Epidemiologic issues in studies of association between apical periodontitis and systemic health. Endod Top 2004;8:15-35.
49. Baumgartner JC. Microbiologic and pathologic aspects of endodontics. Curr Opin Dent 1991;1:737-43.
50. Sundqvist G. Ecology of the root canal flora. J Endod 1992;18:427-30.
51. Miller GA, DeMayo T, Hutter JW. Production of interleukin-1 by polymorphonuclear leukocytes resident in periradicular tissue. J Endod 1996;22:346-51. (Pubitemid 126730468)
52. Kuo ML, Lamster IB, Hasselgren G. Host mediators in endodontic exudates. I. Indicators of inflammation and humoral immunity. J Endod 1998;24:598-603.
53. Marton I, Kiss C, Balla G, Szabo T, Karmazsin L. Acute phase proteins in patients with chronic periapical granuloma before and after surgical treatment. Oral Microbiol Immunol 1988;3:95-6.
54. Marton IJ, Kiss C. Influence of surgical treatment of periapical lesions on serum and blood levels of inflammatory mediators. Int Endod J 1992;25:229-33.
55. Joshipura KJ, Pitiphat W, Hung H, Willett WC, Coldtiz GA, Douglass CW. Pulpal inflammation and incidence of coronary heart disease. J Endod 2006 Feb;32:99-103. (Pubitemid 43309635)
56. Frisk F, Hakeberg M. A 24-year follow-up of root filled teeth and periapical health amongst middle aged and elderly women in Göteborg, Sweden. Int Endod J 2005 Apr;38(4):246-54. (Pubitemid 40522589)
57. Frisk F, Hakeberg M. Socioeconomic risk indicators for apical periodontitis. Acta Odontol Scand 2006 April;64(2):123-8.
58. Frisk F. Epidemiological Aspects on Apical Periodontitis. Studies based on the Prospective Population Study of Women in Göteborg and the Population Study on Oral Health in Jönköping, Sweden. Department of Endodontology/Oral Diagnosis Institute of Odontology, The Sahlgrenska Academy, Göteborg University; 2007.
59. Caplan DJ, Pankow S, Cai J, Offenbacher S, Beck JD. The relationship between self-reported history of endodontic therapy and coronary heart disease in the atherosclerosis risk in communities study. J Am Dent Assoc 2009;140:1004-12.
60. Coats AJ. Ethical authorship and publishing. Int J Cardiol 2009;131:149-50.