Contribution of brain dopamine, serotonin and opioid receptors in the mechanisms of neuroimmunomodulation: Evidence from pharmacological analysis

International Immunopharmacology

Volumn 12, Issue 4, 2012, Pages 618-625

  Idova, Galina V ^a   Alperina, Elizaveta L ^a   Cheido, Margarita A ^a  

^a INSTITUTE OF PHYSIOLOGY   (Russian Federation)

Author keywords

Dopamine; Immunomodulation; Neuromediator receptors; Opioids; Psychoemotional state; Serotonin

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 5,9 DIETHYL 2 (3 FURYLMETHYL) 2' HYDROXY 6,7 BENZOMORPHAN; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; AMFEBUTAMONE; APOMORPHINE; CYPROHEPTADINE; DOPAMINE RECEPTOR; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; HALOPERIDOL; IPSAPIRONE; KETANSERIN; LEUCINE ENKEPHALIN[2 DEXTRO SERINE 6 THREONINE]; LYSERGIDE; N (TETRAHYDROFURFURYL)NORMETAZOCINE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; N,N DIALLYLTYROSYL 2 METHYLALANYL 2 METHYLALANYLPHENYLALANYLLEUCINE; NALOXONE; OPIATE RECEPTOR; QUINPIROLE; SEROTONIN RECEPTOR; STAT6 PROTEIN;

AGGRESSIVENESS; ANXIETY; CD8+ T LYMPHOCYTE; DEPRESSION; HUMAN; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOMODULATION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; REVIEW; SCHIZOPHRENIA; SINGLE DRUG DOSE; TUMOR GROWTH;

ANIMALS; BRAIN; HUMANS; NEUROIMMUNOMODULATION; RECEPTORS, DOPAMINE; RECEPTORS, OPIOID; RECEPTORS, SEROTONIN;

EID: 84858129053     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2012.02.010     Document Type: Review

References (127)

1. D.H. Overstreet, R.C. Commissaris, R. De La Garza, S.E. File, D.J. Knapp, and L.S. Seiden Involvement of 5-HT1A receptors in animal tests of anxiety and depression: evidence from genetic models Stress 6 2 2003 101 110 (Pubitemid 36681960)
2. Y. Goto, and A.A. Grace The dopamine system and the pathophysiology of schizophrenia: a basic science perspective Int Rev Neurobiol 78 2007 41 68
3. G. Silkis A role of opioid receptor agonists and antagonists in the treatment of Parkinson's disease Neurochemistry 24 4 2007 297 303
4. B.W. Dunlop, and C.B. Nemeroff The role of dopamine in the pathophysiology of depression Arch Gen Psychiatry 64 3 2007 327 337 (Pubitemid 46376789)
5. M. Di Forti, J.M. Lappin, and R.M. Murray Risk factors for schizophrenia - all roads lead to dopamine Eur Neuropsychopharmacol 17 2 2007 101 107
6. K.A. Miczek, J.J. Yap, and H.E. Covington Social stress, therapeutics and drug abuse: preclinical models of escalated and depressed intake Pharmacol Ther 120 2 2008 102 128
7. J.F. Randal-Thompson, K.A. Pescatore, and E.M. Unterwald A role for delta opioid receptors in the central nucleus of the amygdala in anxiety-like behaviors Psychopharmacology (Berl) 212 4 2010 585 595
8. U. Fiszer Selected aspects of immunological disorders in Parkinson's disease Neurol Neurochir Pol 38 2004 63 66
9. L. Capuron, A. Miller, and M.R. Irwin Psychoneuroimmunology of depressive disorder: mechanisms and clinical implications Psychoneuroimmunology 1 2007 509 530
10. N. Müller, and M.J. Schwarz Immune system and schizophrenia Curr Immunol Rev 3 3 2010 213 220
11. L.V. Devoino, and RYu Ilyuthchenok Influence of some drugs on the immune response. II. Effects of serotonin, 5-hydroxytryptophan, reserpine and iproniazid on delayed hypersensitivity Eur J Pharmacol 4 1968 449 456
12. L. Devoino, and G. Idova Influence of some drugs on the immune response. IV. Effect of serotonin, 5-hydroxytryptophan, iproniazid and p-chlorphenylalanine on the synthesis of IgM and IgG antibodies Eur J Pharmacol 22 1973 325 331
13. J.C. Jackson, R.J. Cross, and W.K. Markesbery Influence of serotonin on the immune response Immunology 54 1985 505 512 (Pubitemid 15132707)
14. M. Boranic, D. Pericic, M. Poljak-Blazi, V. Sverko, and T. Marotti Suppression of immune response in rats by stress and drugs interfering with metabolism of serotonin Ann N Y Acad Sci 496 1987 485 491
15. L. Devoino, E. Alperina, and G. Idova Dopaminergic stimulation of the immune reaction: interaction of serotoninergic and dopaminergic systems in neuroimmunomodulation Int J Neurosci 40 1988 271 288
16. L. Devoino, N. Morozova, and M. Cheido Participation of serotoninergic system in neuroimmunomodulation: intraimmune mechanisms and the pathways providing an inhibitory effect Int J Neurosci 40 3-4 1988 111 128
17. L. Devoino, G. Idova, E. Alperina, and M. Cheido Brain neuromediator systems in the immune response control: pharmacological analysis of pre- and postsynaptic mechanisms Brain Res 633 1994 267 274 (Pubitemid 24021270)
18. L. Devoino, E. Alperina, O. Galkina, and R. Ilyutchenok Involvement of brain dopaminergic structures in neuroimmunomodulation Int J Neurosci 91 3-4 1997 213 228 (Pubitemid 27490965)
19. Devoino LV, Idova GV, Alperina EL. Psychoneuroimmunomodulation: behavior and immunity. A role for the neuromediator pattern of the brain. Ed. "Nauka": Novosibirsk, 2009; Russian.
20. C. Delrue, B. Deleplanque, F. Rouge-Pont, S. Vitiello, and P.J. Neveu Brain monoaminergic, neuroendocrine, and immune responses to an immune challenge in relation to brain and behavioral lateralization Brain Behav Immun 8 2 1994 137 152 (Pubitemid 24197047)
21. Y. Qiu, Y. Peng, and J. Wang Immunoregulatory role of neurotransmitters Adv Neuroimmunol 6 1996 223 231 (Pubitemid 26412643)
22. S. Basu, and P.S. Dasgupta Dopamine, a neurotransmitter, influences the immune system J Neuroimmunol 102 2 2000 113 124
23. T.C. Pellegrino, and B.M. Bayer Role of central 5-HT2 receptors in fluoxetine-induced decreases in T lymphocyte activity Brain Behav Immun 16 2002 87 103 (Pubitemid 35425567)
24. P. Sacerdote, E. Limiroli, and L. Gaspani Experimental evidence for immunomodulatory effects of opioids Adv Exp Med Biol 521 2003 106 116 (Pubitemid 36535169)
25. T.B. Saurer, K.A. Carrigan, S.G. Ijames, and D.T. Lysle Suppression of natural killer cell activity by morphine is mediated by the nucleus accumbens shell J Neuroimmunol 173 2006 3 11
26. M.A. Cheido, and G.V. Idova Mu-opioidergic immunomodulation: the neurochemical basis Adv Physiol Sci 40 2 2009 12 25 [Russian]
27. C. Sarkar, B. Basu, D. Chakroborty, P.S. Dasgupta, and S. Basu The immunoregulatory role of dopamine: an update Brain Behav Immun 24 4 2010 525 528
28. P.J. Neveu Brain lateralization and immunomodulation Int J Neurosci 70 1-2 1993 135 143
29. G. Nistico, M.C. Caroleo, M. Arbitrio, and L. Pulvirenti Evidence for an involvement of dopamine D1 receptors in the limbic system in the control of immune mechanisms Neuroimmunomodulation 1 3 1994 174 180
30. C.W. Tsao, Y.S. Lin, and J.T. Cheng Effect of dopamine on immune cell proliferation in mice Life Sci 61 24 1997 361 371
31. H. Engler, R. Doenlen, C. Riether, A. Engler, M.B. Niemi, and H.O. Besedovsky Time-dependent alterations of peripheral immune parameters after nigrostriatal dopamine depletion in rat model of Parkinson's disease Brain Behav Immun 23 4 2009 518 526
32. E.L. Alperina, G.V. Idova, and L.V. Devoino A role for the hypophysis in immunomodulating influence of dopaminergic and serotoninergic systems Ross Fiziol Zh Im I M Sechenova 11 1985 1428 1431 [Russian]
33. L. Devoino, G. Idova, E. Alperina, and M. Cheido Distribution of immunocompetent cells underlying psychoneuroimmunomodulation. Brain neuromediator control mechanisms Ann N Y Acad Sci 496 1987 292 300
34. R.J. Cross, W.H. Brooks, and T.L. Roszman Modulation of T-suppressor cell activity by central nervous system catecholamine depletion J Neurosci Res 18 1987 75 81
35. C.A. Ottaway, and A.J. Husband The influence of neuroendocrine pathways on lymphocyte migration Immunol Today 5 11 1994 511 517
36. L. Devoino, M. Cheido, E. Alperina, and G. Idova Evidence for a role of dopaminergic mechanisms in the immunostimulating effect of μ-opioid receptor agonist DAGO Int J Neurosci 113 2003 1381 1394 (Pubitemid 37362679)
37. R.S. Devi, R.M. Sivaprakash, and A. Namasivayam Rat hippocampus and primary immune response Indian J Physiol Pharmacol 48 3 2004 329 336 (Pubitemid 38954954)
38. A. Nieoullon Dopamine and the regulation of cognition and attention Prog Neurobiol 67 1 2002 53 83 (Pubitemid 34786170)
39. A. Alcaro, R. Huber, and J. Panksepp Behavioral functions of the mesolimbic dopaminergic system: an affective neuroethological perspective Brain Res Rev 56 2 2007 283 321 (Pubitemid 350176598)
40. M.A. Teunis, C.J. Heijnen, A.R. Cools, and A. Kavelaars Reduced splenic natural killer cell activity in rats with a hyperreactive dopaminergic system Psychoneuroendocrinology 29 8 2004 1058 1064 (Pubitemid 38833533)
41. M. Asada, S. Ebihara, Y. Numachi, T. Okazaki, S. Yamanda, and K. Ikeda Reduced tumor growth in a mouse model of schizophrenia, lacking the dopamine transporter Int J Cancer 123 2008 511 518 (Pubitemid 351898407)
42. C. Missale, S.R. Nash, S.W. Robinson, M. Jaber, and M.G. Caron Dopamine receptors: from structure to function Physiol Rev 78 1 1998 189 225 (Pubitemid 28070979)
43. J.M. Beaulieu, and R.R. Gainetdinov The physiology, signalling, and pharmacology of dopamine receptors Pharmacol Rev 63 1 2011 182 217
44. M. Hodaie, J.S. Neimat, and A.M. Lozano The dopaminergic nigrostriatal system and Parkinson's disease: molecular events in development, disease, and cell death, and new therapeutic strategies Neurosurgery 60 1 2007 17 28 (Pubitemid 46102897)
45. L.V. Devoino, E.L. Al'perina, M.A. Cheido, and M.M. Gevorgian Changes in the immune reaction of animals under conditions of drug-induced activation and blockade of D1 dopamine receptors Exp Clin Pharmacol 67 3 2004 48 50 [Russian] (Pubitemid 38938573)
46. J.A. Levy, and G.H. Heppner Alterations of immune reactivity by haloperidol and delta-9-tetrahydrocannadinol J Immunol 3 1981 93 109 (Pubitemid 11034966)
47. G. Idova, M. Cheido, and L. Devoino Modulation of the immune response by changing neuromediator systems activity under stress Int J Immunopharmacol 19 9-10 1997 535 540 (Pubitemid 28261011)
48. L.V. Devoino, E.L. Alperina, M.M. Gevorgyan, and M.A. Cheido Involvement of dopamine D1 and D2 receptors in the rat nucleus accumbens in immunostimulation Neurosci Behav Physiol 37 2 2007 147 151 (Pubitemid 46023996)
49. P. Seeman Targeting the dopamine D2 receptor in schizophrenia Expert Opin Ther Targets 10 4 2006 515 531
50. E.L. Alperina, and M.M. Gevorgyan Functional interplay of dopamine D1 and D2 receptors in the immune response control in different psychoemotional states Exp Clin Pharmacol 73 6 2010 2 4 [Russian]
51. L. Devoino, E. Alperina, N. Kudryavtseva, and N. Popova Immune responses in male mice with aggressive and submissive behavior patterns: strain differences Brain Behav Immun 7 1993 91 96 (Pubitemid 23227065)
52. L. Devoino, E. Alperina, and T. Pavina Immunological consequences of the reversal of social status in C57BL/6J mice Brain Behav Immun 17 2003 28 34 (Pubitemid 36207599)
53. J.M. Petitto Behavioral genetics and immunity Psychoneuroimmunology 2 2001 173 186
54. V. Stefanski Social stress in laboratory rats: behavior, immune function, and tumor metastasis Physiol Behav 73 3 2001 385 391 (Pubitemid 32595714)
55. E. Merlot, E. Moze, and A. Bartolomucci The rank assessed in a food competition test influences subsequent reactivity to immune and social challenges in mice Brain Behav Immun 18 5 2004 468 475 (Pubitemid 38950842)
56. R.J. Blanchard, C.R. McKittrick, and D.C. Blanchard Animal models of social stress: effects on behavior and brain neurochemical system Physiol Behav 73 3 2001 261 271 (Pubitemid 32595699)
57. L. Devoino, E. Alperina, E. Podgornaja, R. Ilyutchenok, G. Idova, and O. Poljakov Regional changes of brain serotonin and its metabolite 5-hydroxyindolacetic acid and development of immunosuppression in submissive mice Int J Neurosci 114 2004 1049 1062 (Pubitemid 39208475)
58. N.K. Popova, V.S. Naumenko, A.S. Cybko, and D.V. Bazovkina Receptor-genes cross-talk: effect of chronic 5-HT(1A) agonist 8-hydrohy-2(di-n-propylamino) tetralin treatment on the expression of key genes in brain serotonin system and on behavior Neuroscience 169 1 2010 229 235
59. G.V. Idova, M.A. Cheido, and E.N. Zhukova Effects of activation and blockade of dopamine D(2) receptors on the immune response in mice with different types of behavior Neurosci Behav Physiol 37 7 2007 725 729 (Pubitemid 47365309)
60. M. Cheido, G. Idova, and L. Devoino Involvement of delta-opioid receptors in immunosuppression Int J Neurosci 84 1996 195 203
61. K.D. Alex, and E.A. Pehek Pharmacologic mechanisms of serotoninergic regulation of dopamine neurotransmission Pharmacol Ther 113 2 2007 296 320 (Pubitemid 46149046)
62. G. Di Giovanni, E. Esposito, and V. Di Matteo Role of serotonin in central dopamine dysfunction CNS Neurosci Ther 16 2010 179 194
63. H.S. Jørgensen Studies on the neuroendocrine role of serotonin Dan Med Bull 54 4 2007 266 288 (Pubitemid 351890220)
64. J. Borg Molecular imaging of the 5-HT(1A) receptor in relation to human cognition Behav Brain Res 195 1 2008 103 111
65. H. Jovanic, A. Perski, H. Berglund, and I. Savic Chronic stress is linked to 5-HT1A receptor changes and functional disintegration of the limbic networks Neuroimage 55 3 2011 1178 1188
66. H.Y. Meltzer, Z. Li, Y. Kaneda, and J. Ichikawa Serotonin receptors: their key role in drugs to treat schizophrenia Prog Neuropsychopharmacol Biol Psychiatry 27 7 2003 1159 1172 (Pubitemid 37464960)
67. K.E. Morrison, C.L. Swallows, and M.A. Cooper Effects of dominance status on conditioned defeat and expression of 5-HT1A and 5-HT2A receptors Physiol Behav 104 2 2011 283 290
68. M. Boldrini, M.D. Underwood, J.J. Mann, and V. Arango Serotonin-1A autoreceptor binding in the dorsal raphe nucleus of depressed suicides J Psychiatr Res 42 6 2008 433 442 (Pubitemid 351240919)
69. M. Barnes, and T. Sharp A review of central 5-HT1A receptors and their function Neuropharmacology 38 1999 1083 1152 (Pubitemid 29292403)
70. P. Celada, M. Puig, M. Amargos-Bosch, A. Adell, and F. Artigas The therapeutic role of 5-HT1A and 5-HT2A receptors in depression J Psychiatry Neurosci 29 4 2004 252 265 (Pubitemid 39185866)
71. L. Schiller, M. Donix, M. Jankel, and J. Oehler Serotonin 1A and 2A receptor densities, neurochemical and behavioural characteristics in two closely related mice strains after long-term isolation Prog Neuropsychopharmacol Biol Psychiatry 30 3 2006 492 503 [72] (Pubitemid 43841737)
72. 1A receptor activation a possible mechanism of atypical antipsychotic-induced cortical dopamine release J Neurochem 76 2001 1521 1531 (Pubitemid 32198256)
73. N.M. Richtand, J.A. Welge, A.D. Logue, P.E. Keck Jr., S.M. Strakowski, and R.K. McNamara Role of serotonin and dopamine receptor binding in antipsychotic efficacy Prog Brain Res 72 2008 155 175
74. C. Crisafulli, C. Fabbri, S. Porcelli, A. Drago, E. Spina, and D. De Ronchi Pharmacogenetics of antidepressants Front Pharmacol 2 6 2011 1 21
75. R. Mossner, and K.P. Lesche Role of serotonin in the immune system and in neuroimmune interactions Brain Behav Immun 12 4 1998 249 271 (Pubitemid 29224829)
76. G.P. Ahern 5-HT and the immune system Curr Opin Pharmacol 11 1 2011 29 33
77. J. Hennig, H. Becher, and P. Netker 5-HT agonist-induced changes in peripheral immune cells in healthy volunteers: the impact of personality Behav Brain Res 73 1-2 1996 359 363 (Pubitemid 26008810)
78. G. Idova, S. Davydova, E. Alperina, M. Cheido, and L. Devoino Serotoninergic mechanisms of immunomodulation under different psychoemotional states: I. A role of 5-HT1A receptor subtype Int J Neurosci 118 2008 1594 1608
79. S.M. Davydova, and G.V. Idova Presynaptic 5-HT1A receptors in immunomodulation Ross Fiziol Zh Im I M Sechenova 3 10 2007 1156 1162 Russian
80. J. Yamada, Y. Sugimoto, and K. Horisaka The behavioural effects of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) in mice Eur J Pharmacol 154 3 1988 299 304
81. A. Fletcher, E.A. Forster, D.J. Bill, G. Brown, I.A. Cliffe, and J.E. Hartley Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent selective and silent 5-HT1A receptor antagonist Behav Brain Res 73 1996 337 353
82. G.V. Idova, and S.M. Davydova Involvement of presynaptic 5-HT1A receptors in immunomodulation in conditions of psychoemotional tension Neurosci Behav Physiol 40 5 2010 495 499
83. G.V. Idova, D.V. Jur'ev, E.N. Zhukova, and S.M. Kuznetsova Immune response in C57BL/6J mice at different stages of depressive-like behavior under activation of pre- and postsynaptic receptors Bull Exp Biol Med 151 3 2011 331 333 [Russian]
84. S. Davydova, M. Cheido, M. Gevorgyan, and G. Idova Effects of 5-HT2A receptor stimulation and blocking on immune response Bull Exp Biol Med 150 2 2010 219 221
85. G. Pineyro, and P. Blier Autoregulation of serotonin neurons: role in antidepressant drug action Pharmacol Rev 51 3 1999 533 591 (Pubitemid 29420214)
86. G.V. Idova, and M.A. Cheido Stimulation of the immune response during blockade of serotonin receptors by cyproheptadine Bull Exp Biol Med 103 1987 440 442 [Russian]
87. M. Amargos-Bosch, A. Bortolozzi, M.V. Puig, J. Serrata, A. Adell, and P. Celada Co-expression and in vivo interaction of serotonin 1A and serotonin 2A receptors in pyramidal neurons of prefrontal cortex Cereb Cortex 14 3 2004 281 299 (Pubitemid 38252721)
88. J.G. Hensler, and K.A. Truett Effect of chronic serotonin-2 receptor agonist or antagonist administration on serotonin-1A receptor sensitivity Neuropsychopharmacology 19 5 1998 354 364 (Pubitemid 28451592)
89. G.A. Carrasco, L.D. Van de Kar, C. Jia, H. Xu, Z. Chen, and R. Chadda Single exposure to a serotonin 1A receptor agonist, (+)8-hydroxy-2-(di-n- propylamino)tetralin, produces a prolonged heterologous desensitization of serotonin 2A receptors in neuroendocrine neurons in vivo J Pharmacol Exp Ther 320 3 2007 1078 1086 (Pubitemid 46294064)
90. C.J. Reissig, J.R. Eckler, R.A. Rabin, K.C. Rice, and J.C. Winter The stimulus effects of 8-OH-DPAT: evidence for a 5-HT2A receptor-mediated component Pharmacol Biochem Behav 88 3 2008 312 317 (Pubitemid 350116258)
91. H.H. Berendsen Interactions between 5-hydroxytryptamine receptor subtypes: is a disturbed receptor balance contributing to the symptomatology of depression in humans? Pharmacol Ther 66 1995 17 37
92. P.W. Burnet, S.L. Eastwood, and P.J. Harrison 5-HT1A and 5-HT2A receptor mRNAs and binding site densities are differentially altered in schizophrenia Neuropsychopharmacology 15 5 1996 442 455 (Pubitemid 26389868)
93. 2A receptors in neuroendocrine neurons in vivo J Pharmacol Exp Ther 310 1 2004 59 66 (Pubitemid 38812695)
94. A. Coop, and K.C. Rice Role of delta-opioid receptors in biological processes Drug News Perspect 13 13 2000 481 487 (Pubitemid 32063587)
95. L.S. Pohorecky, A. Skiandos, X. Zhang, K.C. Rice, and D. Behjamin Effect of chronic social stress on delta-opioid receptor function in the rat J Pharmacol Exp Ther 290 1 1999 196 206 (Pubitemid 29302320)
96. G. Henriksen, and F. Willoch Imaging of opioid receptors in the central nervous system Brain 131 5 2008 1171 1196
97. M.A. Cheido, G.V. Idova, and L.V. Devoino The serotonin-dependent suppression of the immune response by kappa-opiate receptors Bull Exp Biol Med 9 1993 291 292 [Russian]
98. J. Kowalski Immunomodulatory action of class mu-, delta- and kappa-opioid receptor agonists in mice Neuropeptides 32 4 1998 301 306 (Pubitemid 28439216)
99. M. Dimitrijevic, S. Stanojevic, V. Kovaevi-Jovanovic, T. Miletic, V. Vuji-Redic, and E. Radulovic Modulation of humoral immune responses in the rat by centrally applied Met-Enk and opioid receptor antagonists: functional interactions of brain OP1, OP2 and OP3 receptors Immunopharmacology 49 3 2000 255 262
100. C.J. Nelson, G.M. Schneider, and D.T. Lysle Involvement of central μ- but not δ- or κ-opioid receptors in immunomodulation Brain Behav Immun 14 3 2000 170 184 (Pubitemid 32280873)
101. M.A. Cheido, and M.M. Gevorgyan Peculiarities of the distribution of cellular subpopulations in the spleen and peripheral blood of CBA mice under conditions of activation of the mu- and delta-opioid systems Immunology 5 2011 248 250 [Russian]
102. C. Gaveriaux-Ruff, F. Simonin, D. Filliol, and B.L. Kieffer Enhanced humoral response in kappa-opioid receptor knockout mice J Neuroimmunol 134 1-2 2003 72 81 (Pubitemid 36050832)
103. M.A. Cheido, and G.V. Idova Effect of opioid peptides on immunomodulation Ross Fiziol Zh Im I M Sechenova 84 4 1998 385 390 [Russian]
104. S. Matsuzaki, H. Ikeda, G. Akiyama, M. Sato, S. Moribe, and T. Suzuki Role of mu- and delta-opioid receptors in the nucleus accumbens in turning behaviour of rats Neuropharmacology 46 8 2004 1089 1096 (Pubitemid 38529932)
105. M.A. Cheido, and G.V. Idova The contribution of serotonin 1A receptors to kappa opioid immunosuppression Neurosci Behav Physiol 39 6 2009 587 590
106. M.A. Cheido, and G.V. Idova Role of serotonin receptors in the delta-opioid immunosuppression Ross Fiziol Zh Im I M Sechenova 96 12 2010 1234 1240 [Russian]
107. C.J. Fowler, and C.L. Fraser μ-, δ-, κ-Opioid receptors and their subtypes. A critical review with emphasis on radioligand binding experiments Neurochem Int 24 5 1994 401 426
108. P. Cadet Mu opiate receptor subtypes Med Sci Monit 10 6 2004 28 32
109. C. Ulens, M. Van Boven, P. Daenens, and J. Tytgat Interaction of p-fluorofentanyl on cloned human opioid receptors and exploration of the role of Trp-318 and His-319 in μ-opioid receptor selectivity J Pharmacol Exp Ther 294 3 2000 1024 1033 (Pubitemid 30666855)
110. D.D. Taub, T.K. Eisenstein, E.B. Geller, M.W. Adler, and T.J. Rogers Immunomodulatory activity of mu- and kappa-selective opioid agonists Proc Natl Acad Sci U S A 88 2 1991 360 364
111. S.V. Gein, T.A. Simonenko, and V.A. Chereshnev Effect of beta-endorphin and DAGO, a selective agonist of mu-opioid receptors, on the proliferative activity of lymphocytes Dokl Biol Sci 391 2003 289 291 [Russian]
112. I. Szabo, M. Rojavin, J.L. Bussiere, T.K. Eisenstein, M.W. Adler, and T.J. Rogers Suppression of peritoneal macrophage phagocytosis of Candida albicans by opioids J Pharmacol Exp Ther 267 2 1993 703 706 (Pubitemid 23352527)
113. N.N. Kudryavtseva, M.A. Gerris, D.F. Avgustinovich, M.V. Tenditnik, and J.M. Van Ree Modulation of anxiety-related behaviors by mu- and kappa-opioid receptor agonists depends on the social status of mice Peptides 25 8 2004 1355 1363 (Pubitemid 39193188)
114. N. Hagelberg, J.K. Kajander, K. Nagren, S. Hinkkas, J. Hietala, and H. Scheinin Mu-receptor agonism with alfentanil increases striatal dopamine D2 receptor binding in man Synapse 45 1 2002 25 30 (Pubitemid 34595060)
115. L.M. Ambrose, E.M. Unterwald, and E.J. Van Bockstaele Ultrastructural evidence for co-localization of dopamine D2 and μ-opioid receptors in the rat dorsolateral striatum Anat Rec A Discov Mol Cell Evol Biol 279A 1 2004 583 591 (Pubitemid 38879989)
116. M.A. Cheido, and G.V. Idova The differential contribution of dopamine D(1) and D(2) receptors to mu-opioidergic immunomodulation Neurosci Behav Physiol 37 7 2007 721 724 (Pubitemid 47365308)
117. L. Negri, R.L. Potenza, R. Corsi, and P. Melchiorri Evidence for two subtypes of δ opioid receptors in rat brain Eur J Pharmacol 196 1991 335 336
118. K.W. Kim, S.J. Kim, B.S. Shin, and H.J. Choi Ligand binding profiles of delta-opioid receptor in human cerebral cortex membranes: evidence of delta-opioid receptor heterogeneity Life Sci 68 14 2001 1649 1656
119. R.V. House, P.T. Thomas, and H.M. Bhargava A comparative study of immunomodulation produced by in vitro exposure to delta opioid receptor agonist peptides Peptides 17 1996 75 81 (Pubitemid 26048991)
120. M.A. Cheido, and G.V. Idova Participation of opiate delta-receptors in immunomodulation Neurosci Behav Physiol 24 6 1994 479 482
121. R.T. Rahim, J.J. Meissler Jr., A. Cowan, T.J. Rogers, E.B. Geller, and J. Gaughan Administration of mu-, kappa- or delta2-receptor agonists via osmotic minipumps suppresses murine splenic antibody responses Int J Immunopharmacol 1 11 2001 2001 2009 (Pubitemid 32835130)
122. L.E. McCarthy, J.F. Nitsche, J.E. Pintar, and T.J. Rogers The delta-opioid receptor participates in T-cell development by promoting negative selection J Neuroimmunol 153 1-2 2004 91 98 (Pubitemid 38950931)
123. F.H. Hucklebridge, B.N. Hudspith, B.N. Lydyard, and J. Brostoff Stimulation of human peripheral lymphocytes by methionine enkephalin and delta-selective opioid analogues Immunopharmacology 19 2 1990 87 91 (Pubitemid 20101557)
124. 4-10 increase mitotic activity of hepatocytes and suppress antibody production Bull Exp Biol Med 135 5 2004 505 507 [Russian]
125. J. Radulovic, and B.D. Jankovic Opposing activities of brain opioid receptors in the regulation of humoral and cell-mediated immune responses in the rat Brain Res 661 1-2 1994 189 195 (Pubitemid 24314719)
126. E.L. Morgan Regulation of human B lymphocyte activation by opioid peptide hormones. Inhibition of IgG production by opioid receptor class (mu-, kappa-, and delta) selective agonists J Neuroimmunol 65 1 1996 21 30
127. M.A. Cheido, and G.V. Idova Immune response of submissive and aggressive mice under conditions of opioid receptor activation Bull Exp Biol Med 148 6 2009 886 888 [Russian]