Production of cytokine and chemokines by human mononuclear cells and whole blood cells after infection with Trypanosoma cruzi;Produção de citocinas e quimiocinas por células mononucleares e células do sangue total humano após infecção com Trypanosoma cruzi

Revista da Sociedade Brasileira de Medicina Tropical

Volumn 45, Issue 1, 2012, Pages 45-50

  Rezende Oliveira, Karine ^a   Sarmento, Ronaldo Rodrigues ^b   Junior, Virmondes Rodrigues ^c  

^a Faculdade de Medicina Veterinária   (Brazil)

^b FEDERAL UNIVERSITY OF PARAÍBA   (Brazil)

^c FEDERAL UNIVERSITY OF TRIÂNGULO MINEIRO   (Brazil)

Author keywords

Chemokines; Cytokines; Innate immunity; Trypanosoma cruzi

Indexed keywords

CXCL3 CHEMOKINE; CXCL9 CHEMOKINE; INTERLEUKIN 10; INTERLEUKIN 12; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRITE; PARASITE ANTIGEN; RANTES; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ADAPTIVE IMMUNITY; ADULT; ARTICLE; CELL STIMULATION; CHAGAS DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HOST PARASITE INTERACTION; HUMAN; HUMAN CELL; IMMUNOREGULATION; INNATE IMMUNITY; LEUKOCYTE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; TH1 CELL; TRYPANOSOMA CRUZI; TRYPOMASTIGOTE;

ADOLESCENT; ADULT; ANIMALS; BLOOD CELLS; CERCOPITHECUS AETHIOPS; CHAGAS DISEASE; CHEMOKINES; CYTOKINES; ENZYME-LINKED IMMUNOSPOT ASSAY; HUMANS; IMMUNITY, INNATE; LEUKOCYTES, MONONUCLEAR; NITRITES; TRYPANOSOMA CRUZI; VERO CELLS; YOUNG ADULT;

TRYPANOSOMA CRUZI;

EID: 84858126305     PISSN: 00378682     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0037-86822012000100009     Document Type: Article

References (39)

1. Kirchhoff LV, Weiss LM, Wittner M, Tanowitz HB. Parasitic diseases of the heart. Front Biosci 1998; 9:706-723.
2. World Health Organization. New global effort to eliminate Chagas disease. Weekly Epidemiol Rec 2007; 82:259-260.
3. Muñoz-Fernandez MA, Fernandez, MA, Fresno M. Synergism between tumor necrosis factor-alpha and interferon-gamma on macrophage activation for the killing of intracellular Trypanosoma cruzi through a nitric oxide-dependent mechanism. Eur J Immunol 1992; 22:301-307.
4. Campos MAS, Almeida IC, Takeuchi O, Akira S, Valente EP, Procópio DO, et al. Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite. J Immunol 2001; 167:416-423.
5. Van Voorhis WC. Coculture of human peripheral blood mononuclear cells with Trypanosoma cruzi leads to proliferation of lymphocytes and cytokine production. J Immunol 1992; 148:239-248.
6. Melo RCN, Machado CRS. Trypanosoma cruzi: peripheral blood monocytes and heart macrophages in the resistance to acute experimental infections in rats. Exp Parasitol 2001; 95:15-23.
7. Silva JS, Aliberti JCS, Martins GA, Souza MA, Souto JT, Pádua MA. The role of IL-12 in experimental Trypanosoma cruzi infection. Braz J Med Biol Res 1998; 31:111-115.
8. Melo RC, Fabrino DL, D'Avila H, Teixeira HC, Ferreira AP. Production of hydrogen peroxide by peripheral blood monocytes and specific macrophages during experimental infection with Trypanosoma cruzi in vivo. Cell Biol Int 2003; 27:853-861.
9. Kopp E, Medzhitov R. Recognition of microbial infection by Toll-like receptors. Curr Opin Immunol 2003; 15:396-401.
10. Netea MG, Van der Meer JW, Kullberg BJ. Toll-like receptors as an escape mechanism from the host defense. Trends Microbiol 2004; 12:484-488.
11. Flandin JF, Chano F, Descoteaux A. RNA interference reveals a role for TLR2 and TLR3 in the recognition of Leishmania donovani promastigotes by interferon- gamma-primed macrophages. Eur J Immunol 2006; 36:411-420.
12. Ropert C, Gazzinelli RT. Regulatory role of Toll-like receptor 2 during infection with Trypanosoma cruzi. J Endotoxin Res 2004; 10:425-430.
13. Silva JS, Machado FS, Martins GA. The role of nitric oxide in the pathogenesis of Chagas disease. Front Biosci 2003; 1:314-325.
14. Golgher D, Gazzinelli RT. Innate and acquired immunity in the pathogenesis of Chagas disease. Autoimmunity 2004; 37:399-409.
15. Green LC, Tannenbaum SR, Goldman P. Nitrate synthesis in the germ-free and conventional rat. Science 1981; 212:56-58.
16. Hunter CA, Ellis-Neyes LA, Slifer T, Kanaly S, Grünig G, Fort M, et al. IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruzi. J Immunol 1997; 158:3311-3316.
17. Aliberti JCS, Cardoso MAG, Martins GA, Gazzinelli RT, Vieira LQ, Silva JS. Interleukin-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes. Infect Immun 1996; 64:1961-1967.
18. Silva, JS, Vespa, GNR, Cardoso, MAG, Aliberti, JCS, Cunha, FQ. Tumor necrosis factor alpha mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected gamma interferon-activated macrophages. Infect Immun 1995; 63:4862-67.
19. Talvani A, Ribeiro CS, Aliberti JCS, Michailowsky V, Santos PVA, Murta SMF, et al. Kinetics of cytokine gene expression in experimental chagasic cardiomyopathy: tissue parasitism and endogenous IFN-g as important determinants of chemokine mRNA expression during infection with Trypanosoma cruzi. Microbes Infect 2000; 2:851-866.
20. Baggiolini M, Loetscher P. Chemokines in inflammation and immunity. Immunol Today 2000; 21:418-420.
21. Guiñazú N, Pellegrini A, Carrera EA, Aoki MP, Cabanillas AM, Gìronés N, et al. Immunisation with a major Trypanosoma cruzi antigen promotes pro- inflammatory cytokines, nitric oxide production and increases TLR2 expression. Int J Parasitol 2007; 37:1243-1254.
22. Coelho PS, Klein A, Talvani A, Coutinho SF, Takeuchi O, Akira S, et al. Glycosylphosphatidylinositol-anchored mucin-like glycoproteins isolated from Trypanosoma cruzi trypomastigotes induced in vivo leukocyte recruitment dependent on MCP-1 production by IFN-g-primed-macrophages. J Leuk Biol 2002; 71:837-844.
23. Vitelli-Avelar DM, Sathler-Avelar R, Teixeira-Carvalho A, Pinto Dias JE, Gontijo D, Faria AM, et al. Strategy to assess the overall cytokine profile of circulating leukocytes and its association with distinct clinical forms of human Chagas disease. Scand J Immunol 2008; 68:516-525.
24. Campos MA, Gazzinelli RT. Trypanosoma cruzi and its components as exogenous mediators of inflammation recognized through Toll-like receptors. Mediators Inflamm 2004; 13:139-143.
25. Willment JA, Brown GD. C-type lectin receptors in antifungal immunity. Trends Microbiol 2008; 16:27-32.
26. Gazzinelli RT, Oswald IP, Hieny S, James SL, Sher A. The microbicidal activity of interferon g-treated macrophages against Trypanosoma cruzi involves an L-arginine- dependent, nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-b. Eur J Immunol 1992; 22:2501-2506.
27. Abrahamsohn IA. Cytokines in innate and acquired immunity to Trypanosoma cruzi infection. Braz J Med Biol Res 1998; 31:117-121.
28. Biswas SK, Sodhi A, Paul S. Regulation of nitric oxide production by murine peritoneal macrophages treated in vitro with chemokine monocyte chemoattractant protein 1. Nitric Oxide 2001; 5:566-579.
29. Reed SG, Browneell C E, Russo DM, Silva JS, Grabstein KH, Morrissey PJ. IL-10 mediates susceptibility to Trypanosoma cruzi infection. J Immunol 1994; 153:3135-3140.
30. Abrahamsohn IA, Coffman RL. Trypanosoma cruzi: IL-10, TNF, IFN-gamma, and IL-12 regulate innate and acquired immunity to infection. Exp Parasitol 1996; 84:231-244.
31. Villalta F, Zhang Y, Bibb KE, Kappes JC, Lima MF. The cysteine-cysteine family of chemokines RANTES, MIP-1 alpha and MIP-1 beta induce trypanocidal activity in human macrophage via nitric oxide. Infect Immun 1998; 66:4690-4695.
32. Aliberti JCS, Machado FS, Gazzinelli RT, Teixeira MM, Silva JS. Platelet-activating factor induces nitric oxide synthesis in Trypanosoma cruzi- infected macrophages and mediate resistance to parasite infection in mice. Infect Immun 1999; 67:2810-2814.
33. Lima ES, Andrade ZA, Andrade SG. TNF-alpha is expressed at sites of parasite and tissue destruction in the spleen of mice acutely infected with Trypanosoma cruzi. Int J Exp Pathol 2001; 82:327-336.
34. Aliberti JCS, Machado FS, Souto JT, Campanelli AP, Teixeira MM, Gazzinelli RT, et al. b-Chemokines enhance parasite uptake and promote nitric oxide-dependent microbiostatic activity in murine inflammatory macrophages infected with Trypanosoma cruzi. Infect Immun 1999; 67:4819-4826.
35. Sallusto F, Lenig D, Mackay CR, Lanzavecchia A. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med 1998; 16:875-883.
36. Teixeira MM, Gazzinelli RT, Silva JS. Chemokines, inflammation and Trypanosoma cruzi infection. Trends Parasitol 2002; 18:262-265.
37. Aliberti JCS, Machado FS, Souto JT, Campanelli AP, Teixeira MM, Gazzinelli RT, et al. b-chemokines enhance parasite uptake and promote nitric oxide-dependent microbistatic activity in murine inflammatory macrophages infected with Trypanosoma cruzi. Infect Immun 1999; 67:4819-4826.
38. Teixeira MM, Gazzinelli RT, Silva JS. Chemokines, inflammation and Trypanosoma cruzi infection. Trends Parasitol 2002; 18:262-265.
39. Hardison JL, Wrightsman RA, Carpenter PM, Lane TE, Manning JE. The chemokines CXCL9 and CXCL10 promote a protective immune response but do not contribute to cardiac inflammation following infection with Trypanosoma cruzi. Infect Immun 2006; 74:125-134.