Establishment of myelinating schwann cells and barrier integrity between central and peripheral nervous systems depend on Sox10

GLIA

Volumn 60, Issue 5, 2012, Pages 806-819

  Fröb, Franziska ^a   Bremer, Magdalena ^a   Finzsch, Markus ^a   Kichko, Tatjana ^a   Reeh, Peter ^a   Tamm, Ernst R ^b   Charnay, Patrick ^c   Wegner, Michael ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

^c ECOLE NORMALE SUPÉRIEURE   (France)

Author keywords

Boundary cap cells; CMT; Glia; HMG; Krox20; Peripheral neuropathy; Sry; Transcriptional control

Indexed keywords

CRE RECOMBINASE; KROX20 PROTEIN; OCTAMER TRANSCRIPTION FACTOR 6; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; TRANSCRIPTION FACTOR SOX10; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; CELL POPULATION; CELL PROLIFERATION; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CONDUCTANCE; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; GENE DELETION; GENE EXPRESSION; MOUSE; MYELIN SHEATH; MYELINATION; NERVE CELL DIFFERENTIATION; NONHUMAN; OLIGODENDROGLIA; PERIPHERAL NERVE; PERIPHERAL NERVOUS SYSTEM; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; SCHWANN CELL; STEM CELL;

ANIMALS; BLOOD-BRAIN BARRIER; CENTRAL NERVOUS SYSTEM; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MYELIN SHEATH; PERIPHERAL NERVOUS SYSTEM; PERIPHERAL NERVOUS SYSTEM DISEASES; SCHWANN CELLS; SCIATIC NERVE; SOXE TRANSCRIPTION FACTORS;

EID: 84858077773     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22310     Document Type: Article

References (45)

1. Aquino JB, Hjerling-Leffler J, Koltzenburg M, Edlund T, Villar MJ, Ernfors P. 2006. In vitro and in vivo differentiation of boundary cap neural crest stem cells into mature Schwann cells. Exp Neurol 198: 438-449.
2. Bermingham JR, Scherer SS, O'Connell S, Arroyo E, Kalla KA, Powell FL, Rosenfeld MG. 1996. Tst-1/Oct-6/SCIP regulates a unique step in peripheral myelination and is required for normal respiration. Genes Dev 10: 1751-1762.
3. Bondurand N, Girard M, Pingault V, Lemort N, Dubourg O, Goossens M. 2001. Human Connexin 32, a gap junction protein altered in the X-linked form of Charcot-Marie-Tooth disease, is directly regulated by the transcription factor SOX10. Hum Mol Genet 10: 2783-2795.
4. Bowles J, Schepers G, Koopman P. 2000. Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators. Dev Biol 227: 239-255.
5. Bremer M, Fröb F, Kichko T, Reeh P, Tamm ER, Suter U, Wegner M. 2011. Sox10 is required for Schwann cell homeostasis and myelin maintenance in the adult peripheral nerve. Glia 59: 1022-1032.
6. Britsch S, Goerich DE, Riethmacher D, Peirano RI, Rossner M, Nave KA, Birchmeier C, Wegner M. 2001. The transcription factor Sox10 is a key regulator of peripheral glial development. Genes Dev 15: 66-78.
7. Chomette D, Frain M, Cereghini S, Charnay P, Ghislain J. 2006. Krox20 hindbrain cis-regulatory landscape: Interplay between multiple long-range initiation and autoregulatory elements. Development 133: 1253-1262.
8. Coulpier F, Decker L, Funalot B, Vallat JM, Garcia-Bragado F, Charnay P, Topilko P. 2010. CNS/PNS boundary transgression by central glia in the absence of Schwann cells or Krox20/Egr2 function. J Neurosci 30: 5958-5967.
9. Desmazieres A, Decker L, Vallat JM, Charnay P, Gilardi-Hebenstreit P. 2008. Disruption of Krox20-Nab interaction in the mouse leads to peripheral neuropathy with biphasic evolution. J Neurosci 28: 5891-5900.
10. Finzsch M, Schreiner S, Kichko T, Reeh P, Tamm ER, Bosl MR, Meijer D, Wegner M. 2010. Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage. J Cell Biol 189: 701-712.
11. Finzsch M, Stolt CC, Lommes P, Wegner M. 2008. Sox9 and Sox10 influence survival and migration of oligodendrocyte precursors in the spinal cord by regulating PDGF receptor {alpha} expression. Development 135: 637-646.
12. Ghislain J, Charnay P. 2006. Control of myelination in Schwann cells: A Krox20 cis-regulatory element integrates Oct6, Brn2 and Sox10 activities. Embo Rep 7: 52-58.
13. Ghislain J, Desmarquet-Trin-Dinh C, Gilardi-Hebenstreit P, Charnay P, Frain M. 2003. Neural crest patterning: Autoregulatory and crest-specific elements co-operate for Krox20 transcriptional control. Development 130: 941-953.
14. Guth SIE, Wegner M. 2008. Having it both ways: Sox protein function between conservation and innovation. Cell Mol Life Sci 65: 3000-3018.
15. Herbarth B, Pingault V, Bondurand N, Kuhlbrodt K, Hermans-Borgmeyer I, Puliti A, Lemort N, Goossens M, Wegner M. 1998. Mutation of the Sry-related Sox10 gene in Dominant megacolon, a mouse model for human Hirschsprung disease. Proc Natl Acad Sci USA 95: 5161-5165.
16. Hjerling-Leffler J, Marmigere F, Heglind M, Cederberg A, Koltzenburg M, Enerback S, Ernfors P. 2005. The boundary cap: A source of neural crest stem cells that generate multiple sensory neuron subtypes. Development 132: 2623-2632.
17. Jaegle M, Ghazvini M, Mandemakers W, Piirsoo M, Driegen S, Levavasseur F, Raghoenath S, Grosveld F, Meijer D. 2003. The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development. Genes Dev 17: 1380-1391.
18. Jaegle M, Mandemakers W, Broos L, Zwart R, Karis A, Visser P, Grosveld F, Meijer D. 1996. The POU factor Oct-6 and Schwann cell differentiation. Science 273: 507-510.
19. Jagalur NB, Ghazvini M, Mandemakers W, Driegen S, Maas A, Jones EA, Jaegle M, Grosveld F, Svaren J, Meijer D. 2011. Functional dissection of the Oct6 Schwann cell enhancer reveals an essential role for dimeric Sox10 binding. J Neurosci 31: 8585-8594.
20. Jessen KR, Mirsky R. 2005. The origin and development of glial cells in peripheral nerves. Nat Rev Neurosci 6: 671-682.
21. Jones EA, Jang SW, Mager GM, Chang LW, Srinivasan R, Gokey NG, Ward RM, Nagarajan R, Svaren J. 2007. Interactions of Sox10 and Egr2 in myelin gene regulation. Neuron Glia Biol 3: 377-387.
22. Jones EA, Lopez-Anido C, Srinivasan R, Krueger C, Chang LW, Nagarajan R, Svaren J. 2011. Regulation of the PMP22 Gene through an Intronic Enhancer. J Neurosci 31: 4242-4250.
23. Joseph NM, Mukouyama YS, Mosher JT, Jaegle M, Crone SA, Dormand EL, Lee KF, Meijer D, Anderson DJ, Morrison SJ. 2004. Neural crest stem cells undergo multilineage differentiation in developing peripheral nerves to generate endoneurial fibroblasts in addition to Schwann cells. Development 131: 5599-5612.
24. Kapur RP. 1999. Early death of neural crest cells is responsible for total enteric aganglionosis in Sox10(Dom)/Sox10(Dom) mouse embryos. Pediatr Dev Pathol 2: 559-569.
25. Kim J, Lo L, Dormand E, Anderson DJ. 2003. SOX10 maintains multipotency and inhibits neuronal differentiation of neural crest stem cells. Neuron 38: 17-31.
26. Kucenas S, Wang WD, Knapik EW, Appel B. 2009. A selective glial barrier at motor axon exit points prevents oligodendrocyte migration from the spinal cord. J Neurosci 29: 15187-15194.
27. Kuhlbrodt K, Herbarth B, Sock E, Hermans-Borgmeyer I, Wegner M. 1998. Sox10, a novel transcriptional modulator in glial cells. J Neurosci 18: 237-250.
28. LeBlanc SE, Ward RM, Svaren J. 2007. Neuropathy-associated Egr2 mutants disrupt cooperative activation of myelin protein zero by Egr2 and Sox10. Mol Cell Biol 27: 3521-3529.
29. Maka M, Stolt CC, Wegner M. 2005. Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect. Dev Biol 277: 155-169.
30. Maro GS, Vermeren M, Voiculescu O, Melton L, Cohen J, Charnay P, Topilko P. 2004. Neural crest boundary cap cells constitute a source of neuronal and glial cells of the PNS. Nat Neurosci 7: 930-938.
31. Paratore C, Goerich DE, Suter U, Wegner M, Sommer L. 2001. Survival and glial fate acquisition of neural crest cells are regulated by an interplay between the transcription factor Sox10 and extrinsic combinatorial signaling. Development 128: 3949-3961.
32. Peirano RI, Goerich DE, Riethmacher D, Wegner M. 2000. Protein zero expression is regulated by the glial transcription factor Sox10. Mol Cell Biol 20: 3198-3209.
33. Reiprich S, Kriesch J, Schreiner S, Wegner M. 2010. Activation of Krox20 gene expression by Sox10 in myelinating Schwann cells. J Neurochem 112: 744-754.
34. Ryu EJ, Wang JY, Le N, Baloh RH, Gustin JA, Schmidt RE, Milbrandt J. 2007. Misexpression of Pou3f1 results in peripheral nerve hypomyelination and axonal loss. J Neurosci 27: 11552-11559.
35. Sock E, Enderich J, Rosenfeld MG, Wegner M. 1996. Identification of the nuclear localization signal of the POU domain protein Tst-1/Oct6. J Biol Chem 271: 17512-17518.
36. Sonnenberg-Riethmacher E, Miehe M, Stolt CC, Goerich DE, Wegner M, Riethmacher D. 2001. Development and degeneration of dorsal root ganglia in the absence of the HMG-domain transcription factor Sox10. Mech Dev 109: 253-265.
37. Southard-Smith EM, Kos L, Pavan WJ. 1998. Sox10 mutation disrupts neural crest development in Dom Hirschsprung mouse model. Nat Genet 18: 60-64.
38. Srinivas S, Watanabe T, Lin CS, William CM, Tanabe Y, Jessell TM, Costantini F. 2001. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol 1: 4.
39. Stolt CC, Rehberg S, Ader M, Lommes P, Riethmacher D, Schachner M, Bartsch U, Wegner M. 2002. Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10. Genes Dev 16: 165-170.
40. Svaren J, Meijer D. 2008. The molecular machinery of myelin gene transcription in Schwann cells. Glia 56: 1541-1551.
41. Topilko P, Schneider MS, Levi G, Baron VEA, Chennoufi AB, Seitanidou T, Babinet C, Charnay P. 1994. Krox-20 controls myelination in the peripheral nervous system. Nature 371: 796-799.
42. Vermeren M, Maro GS, Bron R, McGonnell IM, Charnay P, Topilko P, Cohen J. 2003. Integrity of developing spinal motor columns is regulated by neural crest derivatives at motor exit points. Neuron 37: 403-415.
43. Voiculescu O, Charnay P, Schneider-Maunoury S. 2000. Expression pattern of a Krox-20/Cre knock-in allele in the developing hindbrain, bones, and peripheral nervous system. Genesis 26: 123-126.
44. Wegner M. 2010. All purpose Sox: The many roles of Sox proteins in gene expression. Int J Biochem Cell Biol 42: 381-390.
45. Wegner M, Stolt CC. 2005. From stem cells to neurons and glia: A Soxist's view of neural development. Trends Neurosci 28: 583-588.