Disruption of Krox20-Nab interaction in the mouse leads to peripheral neuropathy with biphasic evolution

Journal of Neuroscience

Volumn 28, Issue 23, 2008, Pages 5891-5900

  Desmazières, Anne ^a,b   Decker, Laurence ^a,b   Vallat, Jean Michel ^c   Charnay, Patrick ^a,b   Gilardi Hebenstreit, Pascale ^a,b  

^a INSERM   (France)

^b ECOLE NORMALE SUPÉRIEURE   (France)

^c DUPUYTREN UNIVERSITY HOSPITAL   (France)

Author keywords

Animal model; Charcot Marie Tooth disease; Cranial ganglia; Hindbrain segmentation; Myelin; Transcription factor

Indexed keywords

KROX20 PROTEIN; MUTANT PROTEIN; MYELIN; NAB PROTEIN; PROTEIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; EARLY GROWTH RESPONSE FACTOR 2; NAB1 PROTEIN, MOUSE; NAB2 PROTEIN, MOUSE; REPRESSOR PROTEIN; TUMOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; DEMYELINATION; DISEASE SEVERITY; FEMALE; GENE EXPRESSION REGULATION; GENE MUTATION; GENE TARGETING; GERM LINE; HOMOZYGOSITY; HYPOMYELINATION; MALE; MOUSE; MYELINATION; NONHUMAN; PARALYSIS; PERIPHERAL NEUROPATHY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; SCHWANN CELL; AMINO ACID SUBSTITUTION; ANIMAL; CELL CULTURE; CELL STRAIN COS1; CERCOPITHECUS; COMPARATIVE STUDY; GENETICS; METABOLISM; MOUSE MUTANT; MYELINATED NERVE; PATHOLOGY; PHYSIOLOGY; PROTEIN BINDING; TIME;

AMINO ACID SUBSTITUTION; ANIMALS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; EARLY GROWTH RESPONSE PROTEIN 2; FEMALE; MALE; MICE; MICE, MUTANT STRAINS; NEOPLASM PROTEINS; NERVE FIBERS, MYELINATED; PERIPHERAL NERVOUS SYSTEM DISEASES; PROTEIN BINDING; REPRESSOR PROTEINS; TIME FACTORS;

EID: 44949186681     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5187-07.2008     Document Type: Article

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