Ultrasound-responsive thrombus treatment with zinc-stabilized gelatin nano-complexes of tissue-type plasminogen activator

Journal of Drug Targeting

Volumn 20, Issue 3, 2012, Pages 224-234

  Uesugi, Yoshiko ^a   Kawata, Hiroyuki ^b   Saito, Yoshihiko ^b   Tabata, Yasuhiko ^a  

^a KYOTO UNIVERSITY   (Japan)

^b NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

Gelatin; Metal ions; T PA; Thrombolytic therapy; Ultrasound

Indexed keywords

CALCIUM ACETATE; GELATIN; MAGNESIUM ACETATE; MONTEPLASE; NANOPARTICLE; ZINC ACETATE; ZINC COMPLEX;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; BLOOD CLOT LYSIS; CELL VIABILITY; CIRCULATION; COMPLEX FORMATION; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG TISSUE LEVEL; FIBRINOLYTIC THERAPY; FIBROBLAST CULTURE; MOLECULAR STABILITY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; THROMBUS; ULTRASOUND;

ANIMALS; CELL LINE; CELL SURVIVAL; DRUG CARRIERS; DRUG COMPOUNDING; ENZYME ACTIVATION; FEMALE; FIBRINOLYTIC AGENTS; FIBROBLASTS; GELATIN; HALF-LIFE; MICE; MICE, INBRED STRAINS; NANOPARTICLES; PRESERVATIVES, PHARMACEUTICAL; RECOMBINANT PROTEINS; SOUND; THROMBOLYTIC THERAPY; TISSUE PLASMINOGEN ACTIVATOR; ZINC ACETATE;

EID: 84858061189     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/1061186X.2011.633259     Document Type: Article

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