New amphiphilic and pH-sensitive hydrogel for controlled release of a model poorly water-soluble drug

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 73, Issue 3, 2009, Pages 345-350

  Colinet, I ^a   Dulong, V ^a   Mocanu, G ^b   Picton, L ^a   Le Cerf, D ^a  

^a UNIVERSITÉ DE ROUEN   (France)

^b PETRU PONI INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Romania)

Author keywords

Alginate g PCL; Amphiphilic; Controlled release; Hydrogels; pH sensitive

Indexed keywords

ALGINIC ACID; CALCIUM ION; POLYCAPROLACTONE; THEOPHYLLINE; WATER;

ARTICLE; BIOCOMPATIBILITY; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CROSS LINKING; DEGRADATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; HYDROGEL; HYDROPHOBICITY; IN VIVO STUDY; INTESTINE FLUID; ION EXCHANGE; MOLECULAR INTERACTION; PH; SIMULATION; STOMACH JUICE; TABLET DISINTEGRATION;

ALGINATES; CALCIUM; CHEMISTRY, PHARMACEUTICAL; CROSS-LINKING REAGENTS; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; GLUCURONIC ACID; HEXURONIC ACIDS; HYDROGELS; HYDROGEN-ION CONCENTRATION; POLYESTERS; SOLUBILITY; THEOPHYLLINE;

EID: 70350378864     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2009.07.008     Document Type: Article

References (37)

1. Anton N., Benoit J.P., and Saulnier P. Design and production of nanoparticles formulated from nano-emulsion. J. Control. Release 128 (2008) 185-199
2. Mocanu G., Mihaï D., Le Cerf D., Picton L., and Muller G. Synthesis of new associative gel microsphere from carboxymethyl pullulan and their interactions with lysozyme. Eur. Polym. J. 40 2 (2003) 283-289
3. Jones M.C., and Leroux J.C. Polymeric micelles - a new generation of colloidal drug carriers. Eur. J. Pharm. Biopharm. 48 2 (1999) 101-111
4. Henni-Silhadi W., Deyme M., Boissonnade M.M., Appel M., Le Cerf D., Picton L., and Rosilio V. Enhancement of the solubility and efficacy of poorly water-soluble drugs by hydrophobically-modified polysaccharide derivatives. Pharm. Res. 24 12 (2007) 2317-2326
5. Peppas N.A., Bures P., Leobandung W., and Ichikawa H. Hydrogels in pharmaceutical formulations. Eur. J. Pharm. Biopharm. 50 1 (2000) 27-46
6. Mocanu G., Mihaï D., Picton L., Le Cerf D., and Muller G. Associative polysaccharides gels and their interactions with biological active substance. J. Control. Release 83 (2002) 41-51
7. Peppas N.A. Hydrogels and drug delivery. Curr. Opin. Coll. Inter. Sci. 2 (1997) 531-537
8. Gupta P., Vermani K., and Garg S. Hydrogels: from controlled release to pH-responsive drug delivery. Research Focus 10 (2002) 569-579
9. Colinet I., Picton L., Muller G., and Le Cerf D. pH-dependent stability of scleroglucan borate gels. Carbohydr. Polym. 69 1 (2007) 65-71
10. Sant V.P., Smith D., and Leroux J.C. Novel pH-sensitive supramolecular assemblies for oral delivery of poorly water soluble drugs: preparation and characterization. J. Control. Release 97 (2004) 301-312
11. Inoue T., Chen G., Nakamae K., and Hoffman A.S. A hydrophobically-modified bioadhesive polyelectrolyte hydrogel for drug delivery. J. Control. Release 49 (1997) 167-176
12. Siegel R.A., Falamarzian M., Firestone B.A., and Moxley B.C. pH-controlled release from hydrophobic/polyelectrolyte copolymer hydrogels. J. Control. Release 8 (1988) 179-182
13. Coviello T., Matricardi P., Marianecci C., and Alhaique F. Polysaccharide hydrogels for modified release formulation. J. Control. Release 119 (2007) 5-24
14. Morris E.R. Molecular interactions in polysaccharide gelation. Brit. Polym. J. 18 (1986) 14-21
15. Shiraishi S., Imai T., and Otagiri M. Controlled-release preparation of indomethacin using calcium alginate gel. Biol. Pharm. Bull. 16 (1993) 1164-1168
16. Rousseau I., Le Cerf D., Picton L., Argillier J.F., and Muller G. Entrapment and release of sodium polystyrene sulfonate (SPS) from calcium alginate gel beads. Eur. Polym. J. 40 (2004) 2709-2715
17. Wittaya-Areekul S., Kruenate J., and Prahsarn C. Preparation and in vitro evaluation of mucoadhesive properties of alginate/chitosan microparticles containing prednisolone. Int. J. Pharm. 312 1-2 (2006) 113-118
18. Chen S.C., Wu Y.C., Mi F.L., Lin Y.H., Yu L.C., and Sung H.W. A novel pH-sensitive hydrogel composed of N,O-carboxymethyl chitosan and alginate cross-linked by genipin for protein drug delivery. J. Control. Release 96 (2004) 285-300
19. 2+ ions. React. Funct. Polym. 59 (2004) 129-140
20. George M., and Abraham T.E. Polyionic hydrocolloids for the intestinal delivery of protein drugs: Alginate and chitosan - a review. J. Control. Release 114 (2006) 1-14
21. Colinet I., Dulong V., Hamaide T., Le Cerf D., and Picton L. New amphiphilic modified polysaccharides with original solution behaviour in salt media. Carbohydr. Polym. 75 (2009) 454-462
22. Colinet I., Dulong V., Hamaide T., Le Cerf D., and Picton L. Unusual rheological properties of a new associative polysaccharide in salt media. Carbohydr. Polym. 77 (2009) 743-749
23. Shantha K.L., and Harding D.R.K. Preparation and in vitro evaluation of poly(N-vinyl-2-pyrrolidone-polyethylene glycol diacrylate)-chitosan interpolymeric pH-responsive hydrogels for oral drug delivery. Int. J. Pharm. 207 (2000) 65-70
24. Miyazaki Y., Onuki Y., Yakou S., and Takayama K. Effect of temperature-increase rate on drug release characteristics of dextran microspheres prepared by emulsion solvent evaporation process. Int. J. Pharm. 324 (2006) 144-151
25. .
26. 13C NMR and molecular modeling studies of alginic acid binding with alkaline earth and lanthanide metal ions. Inorg. Chim. Acta 256 (1997) 69-75
27. Sinquin A., Hubert P., and Dellacherie E. Amphiphilic derivatives of alginate: evidence for intra- and intermolecular hydrophobic associations in aqueous solution. Langmuir 9 (1993) 3334-3337
28. Skjåk-Bræk G., Grasdalen H., and Smidsrød O. Inhomogeneous polysaccharide ionic gels. Carbohydr. Polym. 10 (1989) 31-54
29. Rastello De Boisseson M., Leonard M., Hubert P., Marchal P., Stequert A., Castel C., Favre E., and Dellacherie E. Physical alginate hydrogels based on hydrophobic or dual hydrophobic/ionic interactions: Bead formation, structure and stability. J. Coll. Inter. Sci. 273 (2004) 131-139
30. Krishnaiah Y.S.R., Satyanarayana S., Rama Prasad Y.V., and Narasimha Rao S. Gamma scintigraphic studies on guar gum matrix tablets for colonic drug delivery in healthy human volunteers. J. Control. Release 55 (1998) 245-252
31. Liu L.S., Liu S.Q., Steven Y.N., Froix M., Ohno T., and Heller J.J. Controlled release of interleukin-2 for tumour immunotherapy using alginate/chitosan porous microspheres. J. Control. Release 43 (1997) 65-74
32. Dainty A.L., Goulding K.H., Robinson P.K., Simpkins I., and Trevan M.D. Stability of alginate-immobilized algal cells. Biotech. Bioeng. 28 (1986) 209-216
33. Miyazaki S., Kubo W., and Attwood D. Oral sustained delivery of theophylline using in situ gelation of sodium alginate. J. Control. Release 27 (2000) 275-280
34. Liu J., Lin S., Li L., and Liu E. Release of theophylline from polymer blend hydrogels. Int. J. Pharm. 298 (2005) 117-125
35. Coviello T., Alhaique F., Parisi C., Matricardi P., Bocchinfuso G., and Grassi M. A new polysaccharide gel matrix for drug delivery: preparation and mechanical properties. J. Control. Release 102 3 (2005) 643-656
36. Rokhade A.P., Shelke N.B., Patil S.A., and Aminabhavi T.M. Novel interpenetrating polymer network microspheres of chitosan and methylcellulose for controlled release of theophylline. Carbohyd. Polym. 69 (2007) 678-687
37. Coviello T., Grassi M., Lapasin R., Marino A., and Alhaique F. Scleroglucan/borax: characterization of a novel hydrogel system suitable for drug delivery. Biomaterials 24 (2003) 2789-2798